Most cited biochemistry, genetics and molecular biology papers
- Verified
A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic
Madsen, B. E., & Browning, S. R. (2009) · PLoS Genetics
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 1,113
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THE NOD MOUSE: A Model of Immune Dysregulation
Anderson, M. S., & Bluestone, J. A. (2005) · Annual Review of Immunology
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 1,113
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The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
Allen, I. C., Scull, M. A., Moore, C. B., Holl, E. K., McElvania-TeKippe, E., Taxman, D. J., Guthrie, E. H., Pickles, R. J., & Ting, J. P.-Y. (2009) · Immunity
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,113
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SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
Hu, J., Li, X., Coleman, K., Schroeder, A., Ma, N., Irwin, D. J., Lee, E. B., Shinohara, R. T., & Li, M. (2021) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,113
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A benchmark of batch-effect correction methods for single-cell RNA sequencing data
Tran, H. T. N., Ang, K. S., Chevrier, M., Zhang, X., Lee, N. Y. S., Goh, M., & Chen, J. (2020) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,113
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Applying systems-level spectral imaging and analysis to reveal the organelle interactome
Valm, A. M., Cohen, S., Legant, W. R., Melunis, J., Hershberg, U., Wait, E., Cohen, A. R., Davidson, M. W., Betzig, E., & Lippincott-Schwartz, J. (2017) · Nature
Cellular transport and secretionAdvanced Fluorescence Microscopy Techniques
Cited by 1,113
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Somatic mutant clones colonize the human esophagus with age
Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K., Stratton, M. R., et al. (2018) · Science
Cancer Genomics and DiagnosticsEsophageal Cancer Research and Treatment
Cited by 1,113
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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
Tsung, A., Sahai, R., Tanaka, H., Nakao, A., Fink, M. P., Lotze, M. T., Yang, H., Li, J., Tracey, K. J., Geller, D. A., et al. (2005) · The Journal of Experimental Medicine
Advanced Glycation End Products researchOrgan Transplantation Techniques and Outcomes
Cited by 1,113
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Multi-trait analysis of genome-wide association summary statistics using MTAG
23andMe Research Team, Turley, P., Social Science Genetic Association Consortium, Walters, R. K., Maghzian, O., Okbay, A., Lee, J. J., Fontana, M. A., Nguyen-Viet, T. A., Wedow, R., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,112
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The microbiome-gut-brain axis in health and disease
Dinan, T. G., & Cryan, J. F. (2017) · Gastroenterology Clinics of North America
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,111
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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
Fulco, C. P., Nasser, J., Jones, T. R., Munson, G., Bergman, D. T., Subramanian, V., Grossman, S. R., Anyoha, R., Doughty, B. R., Patwardhan, T. A., et al. (2019) · Nature Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,111
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Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,110
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Growth of Candida albicans hyphae
Sudbery, P. E. (2011) · Nature Reviews Microbiology
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 1,110
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Lipids and lipid metabolism in eukaryotic algae
Guschina, I. A., & Harwood, J. L. (2006) · Progress in Lipid Research
Lipid metabolism and biosynthesisAlgal biology and biofuel production
Cited by 1,110
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Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory Drugs
Lehmann, J. M., Lenhard, J. M., Oliver, B. B., Ringold, G. M., & Kliewer, S. A. (1997) · Journal of Biological Chemistry
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 1,110
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Nutrient-sensing mechanisms and pathways
Efeyan, A., Comb, W. C., & Sabatini, D. M. (2015) · Nature
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 1,110
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Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling
Wu, J., Minikes, A. M., Gao, M., Bian, H., Li, Y., Stockwell, B. R., Chen, Z.-N., & Jiang, X. (2019) · Nature
Ferroptosis and cancer prognosisIron Metabolism and Disorders
Cited by 1,110
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Liquid biopsy and minimal residual disease - latest advances and implications for cure
Pantel, K., & Alix-Panabières, C. (2019) · Nature Reviews Clinical Oncology
Cancer Genomics and DiagnosticsAcute Lymphoblastic Leukemia research
Cited by 1,110
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Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
Morin, R. D., O’Connor, M. D., Griffith, M., Kuchenbauer, F., Delaney, A., Prabhu, A.-L., Zhao, Y., McDonald, H., Zeng, T., Hirst, M., et al. (2008) · Genome Research
MicroRNA in disease regulationGenomics and Phylogenetic Studies
Cited by 1,110
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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
Otera, H., Wang, C., Cleland, M. M., Setoguchi, K., Yokota, S., Youle, R. J., & Mihara, K. (2010) · Journal of Cell Biology
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 1,110
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Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome
Brown, V., Jin, P., Ceman, S., Darnell, J. C., O'Donnell, W. T., Tenenbaum, S. A., Jin, X., Feng, Y., Wilkinson, K. D., Keene, J. D., et al. (2001) · Cell
Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms
Cited by 1,109
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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
Wang, S., Gao, J., Lei, Q., Rozengurt, N., Pritchard, C., Jiao, J., Thomas, G. V., Li, G., Roy-Burman, P., Nelson, P. S., et al. (2003) · Cancer Cell
Prostate Cancer Treatment and ResearchPI3K/AKT/mTOR signaling in cancer
Cited by 1,109
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Hypoxia requires Notch signaling to maintain the undifferentiated cell state
Gustafsson, M. V., Zheng, X., Pereira, T., Gradin, K., Jin, S., Lundkvist, J., Ruas, J. L., Poellinger, L., Lendahl, U., & Bondesson, M. (2005) · Developmental Cell
Developmental Biology and Gene RegulationCancer, Hypoxia, and Metabolism
Cited by 1,109
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Epigenetics and gene expression
Gibney, E. R., & Nolan, C. M. (2010) · Heredity
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,109
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