Most cited biochemistry, genetics and molecular biology papers
- Verified
CRISPR-mediated adaptive immune systems in bacteria and archaea
Sorek, R., Lawrence, C. M., & Wiedenheft, B. (2013) · Annual Review of Biochemistry
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 668
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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
Lund, E. G., Guileyardo, J. M., & Russell, D. W. (1999) · Proceedings of the National Academy of Sciences
Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry
Cited by 668
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Dynamic DNA methylation: In the right place at the right time
Luo, C., Hajkova, P., & Ecker, J. R. (2018) · Science
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 668
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A Pathway for Association of Receptors, Adaptors, and Actin during Endocytic Internalization
Kaksonen, M., Sun, Y., & Drubin, D. G. (2003) · Cell
Cellular transport and secretionFungal and yeast genetics research
Cited by 668
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Polydopamine and Eumelanin: From Structure–Property Relationships to a Unified Tailoring Strategy
d’Ischia, M., Napolitano, A., Ball, V., Chen, C.-T., & Buehler, M. J. (2014) · Accounts of Chemical Research
melanin and skin pigmentationPolymer Surface Interaction Studies
Cited by 668
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Effects of Oral Insulin in Relatives of Patients With Type 1 Diabetes
The Diabetes Prevention Trial-Type 1 Study Group (2005) · Diabetes Care
Diabetes and associated disordersDiabetes Management and Research
Cited by 668
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Antibiotics and the Gut Microbiota
Modi, S. R., Collins, J. J., & Relman, D. A. (2014) · Journal of Clinical Investigation
Gut microbiota and healthAntibiotic Use and Resistance
Cited by 667
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Diversity of Human Copy Number Variation and Multicopy Genes
Sudmant, P. H., Kitzman, J. O., Antonacci, F., Alkan, C., Malig, M., Tsalenko, A., Sampas, N., Bruhn, L., Shendure, J., 1000 Genomes Project, et al. (2010) · Science
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 667
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CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
Elchuri, S., Oberley, T. D., Qi, W., Eisenstein, R. S., Jackson Roberts, L., Van Remmen, H., Epstein, C. J., & Huang, T.-T. (2005) · Oncogene
Cancer and biochemical researchRedox biology and oxidative stress
Cited by 667
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Genome flux and stasis in a five millennium transect of European prehistory
Gamba, C., Jones, E. R., Teasdale, M. D., McLaughlin, R. L., Gonzalez-Fortes, G., Mattiangeli, V., Domboróczki, L., Kővári, I., Pap, I., Anders, A., et al. (2014) · Nature Communications
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 667
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Solution structure of the integral human membrane protein VDAC-1 in detergent micelles
Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science
Protein Structure and DynamicsLipid Membrane Structure and Behavior
Cited by 667
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Lysosomal cell death at a glance
Aits, S., & Jäättelä, M. (2013) · Journal of Cell Science
Cell death mechanisms and regulationAutophagy in Disease and Therapy
Cited by 667
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Iron-sulfur proteins: ancient structures, still full of surprises
Beinert, H. (2000) · JBIC Journal of Biological Inorganic Chemistry
Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function
Cited by 667
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A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay
Girirajan, S., Rosenfeld, J. A., Cooper, G. M., Antonacci, F., Siswara, P., Itsara, A., Vives, L., Walsh, T., McCarthy, S. E., Baker, C., et al. (2010) · Nature Genetics
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 667
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Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein
Ma, W.-J., Cheng, S., Campbell, C., Wright, A., & Furneaux, H. (1996) · Journal of Biological Chemistry
RNA Research and SplicingRNA regulation and disease
Cited by 667
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Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor
Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., et al. (2012) · Cell
Cancer Genomics and DiagnosticsRenal cell carcinoma treatment
Cited by 667
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The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
Wakabayashi, J., Zhang, Z., Wakabayashi, N., Tamura, Y., Fukaya, M., Kensler, T. W., Iijima, M., & Sesaki, H. (2009) · Journal of Cell Biology
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 667
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Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse
Lane, N., Dean, W., Erhardt, S., Hajkova, P., Surani, A., Walter, J., & Reik, W. (2003) · genesis
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 667
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Genetic Control of Bone Formation
Karsenty, G., Kronenberg, H. M., & Settembre, C. (2009) · Annual Review of Cell and Developmental Biology
Bone Metabolism and DiseasesAlkaline Phosphatase Research Studies
Cited by 667
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Reverse engineering gene networks using singular value decomposition and robust regression
Yeung, M. K. S., Tegnér, J., & Collins, J. J. (2002) · Proceedings of the National Academy of Sciences
Gene Regulatory Network AnalysisGene expression and cancer classification
Cited by 667
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Activity-dependent neuronal signalling and autism spectrum disorder
Ebert, D. H., & Greenberg, M. E. (2013) · Nature
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 666
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Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb
Janssen-Heininger, Y. M. W., Poynter, M. E., & Baeuerle, P. A. (2000) · Free Radical Biology and Medicine
NF-κB Signaling PathwaysRedox biology and oxidative stress
Cited by 666
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Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor
Bowers, E. M., Yan, G., Mukherjee, C., Orry, A., Wang, L., Holbert, M. A., Crump, N. T., Hazzalin, C. A., Liszczak, G., Yuan, H., et al. (2010) · Chemistry & Biology
Histone Deacetylase Inhibitors ResearchComputational Drug Discovery Methods
Cited by 666
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Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
Ghisletti, S., Barozzi, I., Mietton, F., Polletti, S., De Santa, F., Venturini, E., Gregory, L., Lonie, L., Chew, A., Wei, C.-L., et al. (2010) · Immunity
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 666
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