Most cited biochemistry, genetics and molecular biology papers
- Verified
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
Müller, J., Krijgsman, O., Tsoi, J., Robert, L., Hugo, W., Song, C., Kong, X., Possik, P. A., Cornelissen-Steijger, P. D. M., Foppen, M. H. G., et al. (2014) · Nature Communications
Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations
Cited by 639
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Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes
Horwitz, M. A., & Silverstein, S. C. (1980) · Journal of Clinical Investigation
Legionella and Acanthamoeba researchMicrobial infections and disease research
Cited by 639
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Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett Syndrome
Dani, V. S., Chang, Q., Maffei, A., Turrigiano, G. G., Jaenisch, R., & Nelson, S. B. (2005) · Proceedings of the National Academy of Sciences
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 639
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Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation
Taylor, K. R., & Gallo, R. L. (2006) · The FASEB Journal
Proteoglycans and glycosaminoglycans researchWound Healing and Treatments
Cited by 639
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NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches
Sivandzade, F., Prasad, S., Bhalerao, A., & Cucullo, L. (2019) · Redox Biology
Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways
Cited by 639
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Large Scale Foundation Model on Single-cell Transcriptomics
Hao, M., Gong, J., Zeng, X., Liu, C., Guo, Y., Cheng, X., Wang, T., Ma, J., Song, L., & Zhang, X. (2023) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 639
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Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease
Torres, V. E., Chapman, A. B., Devuyst, O., Gansevoort, R. T., Perrone, R. D., Koch, G., Ouyang, J., McQuade, R. D., Blais, J. D., Czerwiec, F. S., et al. (2017) · New England Journal of Medicine
Genetic and Kidney Cyst DiseasesChronic Kidney Disease and Diabetes
Cited by 639
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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor.
Watson, P. A., Chen, Y. F., Balbas, M. D., Wongvipat, J., Socci, N. D., Viale, A., Kim, K., & Sawyers, C. L. (2010) · Proceedings of the National Academy of Sciences
Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer
Cited by 639
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Selective autophagy: ubiquitin-mediated recognition and beyond
Kraft, C., Peter, M., & Hofmann, K. (2010) · Nature Cell Biology
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 639
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Role of p53 in the Regulation of Cellular Senescence
Mijit, M., Caracciolo, V., Melillo, A., Amicarelli, F., & Giordano, A. (2020) · Biomolecules
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 639
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The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
Yuneva, M. O., Fan, T. W. M., Allen, T. D., Higashi, R. M., Ferraris, D. V., Tsukamoto, T., Matés, J. M., Alonso, F. J., Wang, C., Seo, Y., et al. (2012) · Cell Metabolism
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 639
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Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells
Mazzieri, R., Pucci, F., Moi, D., Zonari, E., Ranghetti, A., Berti, A., Politi, L. S., Gentner, B., Brown, J. L., Naldini, L., et al. (2011) · Cancer Cell
Angiogenesis and VEGF in CancerImmune cells in cancer
Cited by 639
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A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast
Laporte, J., Hu, L. J., Kretz, C., Mandel, J.-L., Kioschis, P., Coy, J. F., Klauck, S. M., Poustka, A., & Dahl, N. (1996) · Nature Genetics
Muscle Physiology and DisordersProtein Tyrosine Phosphatases
Cited by 639
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Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
Berghe, T. V., Vanlangenakker, N., Parthoens, E., Deckers, W., Devos, M., Festjens, N., Guerin, C. J., Brunk, U. T., Declercq, W., & Vandenabeele, P. (2010) · Cell Death & Differentiation
Cell death mechanisms and regulationDeath, Funerary Practices, and Mourning
Cited by 639
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Development of the gut microbiota in infancy and its impact on health in later life
Tanaka, M., & Nakayama, J. (2017) · Allergology International
Gut microbiota and healthInfant Nutrition and Health
Cited by 639
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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes
Hanna, R. N., Carlin, L. M., Hubbeling, H. G., Nackiewicz, D., Green, A. M., Punt, J. A., Geissmann, F., & Hedrick, C. C. (2011) · Nature Immunology
Nuclear Receptors and SignalingImmune cells in cancer
Cited by 639
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Identification and characterization of circular RNAs As a new class of putative biomarkers in human blood
Memczak, S., Papavasileiou, P., Peters, O., & Rajewsky, N. (2015) · PLoS ONE
Circular RNAs in diseasesRNA Research and Splicing
Cited by 639
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Neuroprotection by the Metabolic Antioxidant α-Lipoic Acid
Packer, L., Tritschler, H. J., & Wessel, K. (1997) · Free Radical Biology and Medicine
Biochemical Acid Research StudiesNeuroprotection in Cerebral Ischemia
Cited by 639
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Cobalt Inhibits the Interaction between Hypoxia-inducible Factor-α and von Hippel-Lindau Protein by Direct Binding to Hypoxia-inducible Factor-α
Yuan, Y., Hilliard, G., Ferguson, T., & Millhorn, D. E. (2003) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 638
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Bacterial charity work leads to population-wide resistance
Lee, H. H., Molla, M. N., Cantor, C. R., & Collins, J. J. (2010) · Nature
Bacterial Genetics and BiotechnologyEvolution and Genetic Dynamics
Cited by 638
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Short chain fatty acids prevent high-fat-diet-induced obesity in mice by regulating g protein-coupled receptors and gut microbiota
Lu, Y., Fan, C., Li, P., Lu, Y., Chang, X., & Qi, K. (2016) · Scientific Reports
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 638
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U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation
Kaida, D., Berg, M. G., Younis, I., Kasim, M., Singh, L. N., Wan, L., & Dreyfuss, G. (2010) · Nature
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 638
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The Key Role of Epigenetics in Human Disease Prevention and Mitigation
Feinberg, A. P. (2018) · New England Journal of Medicine
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 638
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Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
Ito, K., Yamamura, S., Essilfie-Quaye, S., Cosio, B., Ito, M., Barnes, P. J., & Adcock, I. M. (2006) · The Journal of Experimental Medicine
Histone Deacetylase Inhibitors ResearchEstrogen and related hormone effects
Cited by 638
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