Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The Hsp90 molecular chaperone: an open and shut case for treatment

Pearl, L. H., Prodromou, C., & Workman, P. (2008) · Biochemical Journal

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 447

Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

Kaeser, P. S., & Regehr, W. G. (2014) · Annual Review of Physiology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 447

Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage

Busino, L., Donzelli, M., Chiesa, M., Guardavaccaro, D., Ganoth, D., Valerio Dorrello, N., Hershko, A., Pagano, M., & Draetta, G. F. (2003) · Nature

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 447

Epitranscriptome sequencing technologies: decoding RNA modifications

Li, X., Xiong, X., & Yi, C. (2017) · Nature Methods

RNA modifications and cancerRNA regulation and disease

Cited by 447

Mitochondrial H + Leak and ROS Generation: An Odd Couple

Brookes, P. S. (2005) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 447

The Iron-Hydrogenase of Thermotoga maritima Utilizes Ferredoxin and NADH Synergistically: a New Perspective on Anaerobic Hydrogen Production

Schut, G. J., & Adams, M. W. W. (2009) · Journal of Bacteriology

Metalloenzymes and iron-sulfur proteinsAnaerobic Digestion and Biogas Production

Cited by 447

The hallmarks of mitochondrial dysfunction in chronic kidney disease

Galvan, D. L., Green, N. H., & Danesh, F. R. (2017) · Kidney International

Mitochondrial Function and PathologyChronic Kidney Disease and Diabetes

Cited by 447

Born to run: control of transcription elongation by RNA polymerase II

Chen, F. X., Smith, E. R., & Shilatifard, A. (2018) · Nature Reviews Molecular Cell Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 447

Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly

Li, Q., Zhou, H., Wurtele, H., Davies, B., Horazdovsky, B., Verreault, A., & Zhang, Z. (2008) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 447

Molecular Basis for Dimethylsulfoxide (DMSO) Action on Lipid Membranes

Notman, R., Noro, M., O'Malley, B., & Anwar, J. (2006) · Journal of the American Chemical Society

Lipid Membrane Structure and BehaviorSpectroscopy and Quantum Chemical Studies

Cited by 447

A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

Hyer, M. L., Milhollen, M. A., Ciavarri, J., Fleming, P., Traore, T., Sappal, D., Huck, J., Shi, J., Gavin, J., Brownell, J., et al. (2018) · Nature Medicine

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 447

Autophagy and cellular immune responses

Ma, Y., Galluzzi, L., Zitvogel, L., & Kroemer, G. (2013) · Immunity

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 447

Evolution of the Rho Family of Ras-Like GTPases in Eukaryotes

Boureux, A., Vignal, E., Faure, S., & Fort, P. (2007) · Molecular Biology and Evolution

Protein Kinase Regulation and GTPase SignalingGenomics and Phylogenetic Studies

Cited by 447

Protein export through the bacterial Sec pathway

Tsirigotaki, A., De Geyter, J., Šoštaric´, N., Economou, A., & Karamanou, S. (2017) · Nature Reviews Microbiology

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 447

Circulating MicroRNA biomarker studies: pitfalls and potential solutions

Witwer, K. W. (2015) · Clinical Chemistry

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 447

Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age

Hansford, R. G., Hogue, B. A., & Mildaziene, V. (1997) · Journal of Bioenergetics and Biomembranes

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 447

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

Kode, A., Rajendrasozhan, S., Caito, S., Yang, S.-R., Megson, I. L., & Rahman, I. (2008) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Genomics, phytochemicals, and oxidative stressSirtuins and Resveratrol in Medicine

Cited by 447

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism.

Hayashi, T., Hirshman, M. F., Fujii, N., Habinowski, S. A., Witters, L. A., & Goodyear, L. J. (2000) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 447

Architecture of the dynamic fungal cell wall

Gow, N. A. R., & Lenardon, M. D. (2023) · Nature Reviews Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 447

Comparative resistance of the 20S and 26S proteasome to oxidative stress

REINHECKEL, T., SITTE, N., ULLRICH, O., KUCKELKORN, U., DAVIES, K. J. A., & GRUNE, T. (1998) · Biochemical Journal

Ubiquitin and proteasome pathwaysRedox biology and oxidative stress

Cited by 447

The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.

Atkinson, G. C., Tenson, T., & Hauryliuk, V. (2011) · PLoS ONE

Bacterial Genetics and BiotechnologyGenomics and Phylogenetic Studies

Cited by 447

CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Klann, T. S., Black, J. B., Chellappan, M., Safi, A., Song, L., Hilton, I. B., Crawford, G. E., Reddy, T. E., & Gersbach, C. A. (2017) · Nature Biotechnology

CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics

Cited by 447

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

Koivunen, P., Hirsilä, M., Günzler, V., Kivirikko, K. I., & Myllyharju, J. (2004) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms

Cited by 447

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

Timmins, J. M., Lee, J.-Y., Boudyguina, E., Kluckman, K. D., Brunham, L. R., Mulya, A., Gebre, A. K., Coutinho, J. M., Colvin, P. L., Smith, T. L., et al. (2005) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 447