Most cited biochemistry, genetics and molecular biology papers
- Verified
Results from a phase I safety trial of hAADC gene therapy for Parkinson disease
Eberling, J. L., Jagust, W. J., Christine, C. W., Starr, P., Larson, P., Bankiewicz, K. S., & Aminoff, M. J. (2008) · Neurology
Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments
Cited by 370
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Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior
Fernández-Gonzalez, R., Moreira, P., Bilbao, A., Jiménez, A., Pérez-Crespo, M., Ramírez, M. A., De Fonseca, F. R., Pintado, B., & Gutiérrez-Adán, A. (2004) · Proceedings of the National Academy of Sciences
Genetic Syndromes and ImprintingReproductive Biology and Fertility
Cited by 370
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Defining an essential transcription factor program for naïve pluripotency
Dunn, S.-J., Martello, G., Yordanov, B., Emmott, S., & Smith, A. G. (2014) · Science
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 370
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Is β-Galactosidase Staining a Marker of Senescence in Vitro and in Vivo?
Severino, J., Allen, R. G., Balin, S., Balin, A., & Cristofalo, V. J. (2000) · Experimental Cell Research
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 370
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A meta-analysis of genome-wide association studies identifies multiple longevity genes
Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., et al. (2019) · Nature Communications
Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms
Cited by 370
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Meta‐Analysis of Gut Dysbiosis in Parkinson's Disease
Nishiwaki, H., Ito, M., Ishida, T., Hamaguchi, T., Maeda, T., Kashihara, K., Tsuboi, Y., Ueyama, J., Shimamura, T., Mori, H., et al. (2020) · Movement Disorders
Gut microbiota and healthParkinson's Disease Mechanisms and Treatments
Cited by 370
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The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)
Bhakar, A. L., Dölen, G., & Bear, M. F. (2012) · Annual Review of Neuroscience
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 370
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Caloric Restriction, the Traditional Okinawan Diet, and Healthy Aging: The Diet of the World's Longest‐Lived People and Its Potential Impact on Morbidity and Life Span
WILLCOX, B. J., WILLCOX, D. C., TODORIKI, H., FUJIYOSHI, A., YANO, K., HE, Q., CURB, J. D., & SUZUKI, M. (2007) · Annals of the New York Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health
Cited by 370
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Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior
Sathyamurthy, A., Johnson, K. R., Matson, K. J. E., Dobrott, C. I., Li, L., Ryba, A. R., Bergman, T. B., Kelly, M. C., Kelley, M. W., & Levine, A. J. (2018) · Cell Reports
Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics
Cited by 370
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Review of harmful gastrointestinal effects of carrageenan in animal experiments.
Tobacman, J. K. (2001) · Environmental Health Perspectives
Carcinogens and Genotoxicity AssessmentPolysaccharides Composition and Applications
Cited by 370
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Fine‐scaled geographical population structuring in a highly mobile marine species: the Atlantic cod
Knutsen, H., Jorde, P. E., André, C., & Stenseth, N. C. (2003) · Molecular Ecology
Genetic diversity and population structureMarine and fisheries research
Cited by 370
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MAPK Signaling Up-regulates the Activity of Hypoxia-inducible Factors by Its Effects on p300
Sang, N., Stiehl, D. P., Bohensky, J., Leshchinsky, I., Srinivas, V., & Caro, J. (2003) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismKruppel-like factors research
Cited by 370
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Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
Grundberg, E., Meduri, E., Sandling, J. K., Hedman, Å. K., Keildson, S., Buil, A., Busche, S., Yuan, W., Nisbet, J., Sekowska, M., et al. (2013) · The American Journal of Human Genetics
Epigenetics and DNA MethylationGenetic Associations and Epidemiology
Cited by 370
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Fzo1p Is a Mitochondrial Outer Membrane Protein Essential for the Biogenesis of Functional Mitochondria in Saccharomyces cerevisiae
Rapaport, D., Brunner, M., Neupert, W., & Westermann, B. (1998) · Journal of Biological Chemistry
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 370
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Characterization of Nucleotide Pools as a Function of Physiological State in Escherichia coli
Buckstein, M. H., He, J., & Rubin, H. (2008) · Journal of Bacteriology
Biochemical and Molecular ResearchBacterial Genetics and Biotechnology
Cited by 370
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TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene, MEC1
Morrow, D. M., Tagle, D. A., Shiloh, Y., Collins, F. S., & Hieter, P. (1995) · Cell
DNA Repair MechanismsFungal and yeast genetics research
Cited by 370
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The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence
DeJong, E. N., Surette, M. G., & Bowdish, D. M. E. (2020) · Cell Host & Microbe
Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms
Cited by 370
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Human Ehlers-Danlos Syndrome Type VII C and Bovine Dermatosparaxis Are Caused by Mutations in the Procollagen I N-Proteinase Gene
Colige, A., Sieron, A. L., Li, S.-W., Schwarze, U., Petty, E., Wertelecki, W., Wilcox, W., Krakow, D., Cohn, D. H., Reardon, W., et al. (1999) · The American Journal of Human Genetics
Connective tissue disorders researchProtease and Inhibitor Mechanisms
Cited by 370
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TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum
Program, N. C. S., Davis, E. E., Zhang, Q., Liu, Q., Diplas, B. H., Davey, L. M., Hartley, J., Stoetzel, C., Szymanska, K., Ramaswami, G., et al. (2011) · Nature Genetics
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 370
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Metformin suppresses diabetes-accelerated atherosclerosis via the inhibition of drp1-mediated mitochondrial fission
Wang, Q., Zhang, M., Torres, G., Wu, S., Ouyang, C., Xie, Z., & Zou, M.-H. (2017) · Diabetes
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 370
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The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos
Sommer, F., Ståhlman, M., Ilkayeva, O., Arnemo, J. M., Kindberg, J., Josefsson, J., Newgard, C. B., Fröbert, O., & Bäckhed, F. (2016) · Cell Reports
Gut microbiota and healthAnimal Nutrition and Physiology
Cited by 370
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Identifying novel constrained elements by exploiting biased substitution patterns
Garber, M., Guttman, M., Clamp, M., Zody, M. C., Friedman, N., & Xie, X. (2009) · Bioinformatics
Genomics and Phylogenetic StudiesGenomics and Chromatin Dynamics
Cited by 370
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Failure to Phosphorylate the Retinoblastoma Gene Product in Senescent Human Fibroblasts
Stein, G. H., Beeson, M., & Gordon, L. (1990) · Science
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 370
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Structure of the membrane domain of respiratory complex I
Efremov, R. G., & Sazanov, L. A. (2011) · Nature
Enzyme Structure and FunctionMitochondrial Function and Pathology
Cited by 370
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