Most cited biochemistry, genetics and molecular biology papers
- Verified
Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians
Ng, M. C. Y., Park, K. S., Oh, B., Tam, C. H. T., Cho, Y. M., Shin, H. D., Lam, V. K. L., Ma, R. C. W., So, W. Y., Cho, Y. S., et al. (2008) · Diabetes
Genetic Associations and EpidemiologyDiabetes and associated disorders
Cited by 362
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Neurodegenerative lysosomal disorders: A continuum from development to late age
Nixon, R. A., Yang, D.-S., & Lee, J.-H. (2008) · Autophagy
Autophagy in Disease and TherapyLysosomal Storage Disorders Research
Cited by 362
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A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., et al. (2019) · Nature Communications
Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging
Cited by 362
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Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
Gerweck, L. E., Vijayappa, S., & Kozin, S. (2006) · Molecular Cancer Therapeutics
Cancer, Hypoxia, and MetabolismDrug Transport and Resistance Mechanisms
Cited by 362
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Distinct Roles for Cellular Retinoic Acid-binding Proteins I and II in Regulating Signaling by Retinoic Acid
Dong, D., Ruuska, S. E., Levinthal, D. J., & Noy, N. (1999) · Journal of Biological Chemistry
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 362
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Diabetes Antibody Standardization Program: first assay proficiency evaluation
Bingley, P. J., Bonifacio, E., Mueller, P. W., & Laboratories, P. (2003) · Diabetes
Diabetes and associated disordersClinical Laboratory Practices and Quality Control
Cited by 362
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Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification
Roberts, P. J., Mitin, N., Keller, P. J., Chenette, E. J., Madigan, J. P., Currin, R. O., Cox, A. D., Wilson, O., Kirschmeier, P., & Der, C. J. (2008) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 362
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Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney
Melk, A., Schmidt, B. M. W., Takeuchi, O., Sawitzki, B., Rayner, D. C., & Halloran, P. F. (2004) · Kidney International
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 362
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Longer Lifespan in Male Mice Treated With a Weakly Estrogenic Agonist, an Antioxidant, an α-Glucosidase Inhibitor or a Nrf2-Inducer
Strong, R., Miller, R. A., Antebi, A., Astle, C. M., Bogue, M., Denzel, M. S., Fernandez, E., Flurkey, K., Hamilton, K. L., Lamming, D. W., et al. (2016) · Aging Cell
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 362
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Heritability and genomics of gene expression in peripheral blood
Wright, F. A., Sullivan, P. F., Brooks, A. I., Zou, F., Sun, W., Xia, K., Madar, V., Jansen, R., Chung, W., Zhou, Y.-H., et al. (2014) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 362
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The role of the mitochondrial permeability transition pore in heart disease
Halestrap, A. P., & Pasdois, P. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion
Cited by 362
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Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
Kielman, M. F., Rindapää, M., Gaspar, C., van Poppel, N., Breukel, C., van Leeuwen, S., Taketo, M. M., Roberts, S., Smits, R., & Fodde, R. (2002) · Nature Genetics
Wnt/β-catenin signaling in development and cancerPluripotent Stem Cells Research
Cited by 362
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177Lu-PSMA-617 versus a change of androgen receptor pathway inhibitor therapy for taxane-naive patients with progressive metastatic castration-resistant prostate cancer (PSMAfore): a phase 3, randomised, controlled trial
Morris, M. J., Castellano, D., Herrmann, K., de Bono, J. S., Shore, N. D., Chi, K. N., Crosby, M., Piulats, J. M., Fléchon, A., Wei, X. X., et al. (2024) · The Lancet
Prostate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and Applications
Cited by 362
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Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
Ghildiyal, M., Xu, J., Seitz, H., Weng, Z., & Zamore, P. D. (2010) · RNA
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 362
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CARNITINE METABOLISM AND ITS REGULATION IN MICROORGANISMS AND MAMMALS
Rebouche, C. J., & Seim, H. (1998) · Annual Review of Nutrition
Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism
Cited by 362
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Taxonomy and function of C1 protein kinase C homology domains
Hurley, J. H., Newton, A. C., Parker, P. J., Blumberg, P. M., & Nishizuka, Y. (1997) · Protein Science
Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics
Cited by 362
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Large-scale protein structure modeling of the Saccharomyces cerevisiae genome
Sánchez, R., & Sali, A. (1998) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 362
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Adult fragile X syndrome: Clinico-neuropathologic findings
Rudelli, R. D., Brown, W. T., Wisniewski, K., Jenkins, E. C., Laure-Kamionowska, M., Connell, F., & Wisniewski, H. M. (1985) · Acta Neuropathologica
Genetics and Neurodevelopmental DisordersDown syndrome and intellectual disability research
Cited by 362
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Cytochrome Oxidase Inhibition Induced by Acute Hydrogen Sulfide Inhalation: Correlation with Tissue Sulfide Concentrations in the Rat Brain, Liver, Lung, and Nasal Epithelium
Dorman, D. C. (2002) · Toxicological Sciences
Sulfur Compounds in BiologyPoisoning and overdose treatments
Cited by 362
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AMP-Activated Protein Kinase: An Ultrasensitive System for Monitoring Cellular Energy Charge
HARDIE, D. G., SALT, I. P., HAWLEY, S. A., & DAVIES, S. P. (1999) · Biochemical Journal
Metabolism, Diabetes, and CancerBiochemical and Molecular Research
Cited by 362
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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
Yu, C., Mannan, A. M., Yvone, G. M., Ross, K. N., Zhang, Y.-L., Marton, M. A., Taylor, B. R., Crenshaw, A., Gould, J. Z., Tamayo, P., et al. (2016) · Nature Biotechnology
Cancer Genomics and DiagnosticsComputational Drug Discovery Methods
Cited by 362
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A compendium of promoter-centered long-range chromatin interactions in the human genome
Jung, I., Schmitt, A., Diao, Y., Lee, A. J., Liu, T., Yang, D., Tan, C., Eom, J., Chan, M., Chee, S., et al. (2019) · Nature Genetics
Genomics and Chromatin DynamicsGenetic Associations and Epidemiology
Cited by 362
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Rerouting Carbon Flux to Enhance Photosynthetic Productivity
Ducat, D. C., Avelar-Rivas, J. A., Way, J. C., & Silver, P. A. (2012) · Applied and Environmental Microbiology
Microbial Metabolic Engineering and BioproductionAlgal biology and biofuel production
Cited by 362
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Individual microtubules in the axon consist of domains that differ in both composition and stability.
Baas, P. W., & Black, M. M. (1990) · The Journal of cell biology
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 362
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