Most cited biochemistry, genetics and molecular biology papers
- Verified
Adipose tissue triglyceride turnover, de novo lipogenesis, and cell proliferation in humans measured with 2 H 2 O
Strawford, A., Antelo, F., Christiansen, M., & Hellerstein, M. K. (2004) · American Journal of Physiology-Endocrinology and Metabolism
Lipid metabolism and biosynthesisAdipose Tissue and Metabolism
Cited by 364
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Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
Baryshnikova, A., Costanzo, M., Kim, Y., Ding, H., Koh, J., Toufighi, K., Youn, J.-Y., Ou, J., San Luis, B.-J., Bandyopadhyay, S., et al. (2010) · Nature Methods
Fungal and yeast genetics researchBioinformatics and Genomic Networks
Cited by 364
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Smed- β catenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration
Petersen, C. P., & Reddien, P. W. (2008) · Science
Planarian Biology and ElectrostimulationDevelopmental Biology and Gene Regulation
Cited by 364
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Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
Oldham, W. M., Clish, C. B., Yang, Y., & Loscalzo, J. (2015) · Cell Metabolism
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 364
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Role of DNA sequence in nucleosome stability and dynamics
Widom, J. (2001) · Quarterly Reviews of Biophysics
Genomics and Chromatin DynamicsDNA and Nucleic Acid Chemistry
Cited by 364
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Phosphorylation of Axin, a Wnt Signal Negative Regulator, by Glycogen Synthase Kinase-3β Regulates Its Stability
Yamamoto, H., Kishida, S., Kishida, M., Ikeda, S., Takada, S., & Kikuchi, A. (1999) · Journal of Biological Chemistry
Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease
Cited by 364
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The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation
Angers, S., Thorpe, C. J., Biechele, T. L., Goldenberg, S. J., Zheng, N., MacCoss, M. J., & Moon, R. T. (2006) · Nature Cell Biology
Wnt/β-catenin signaling in development and cancerUbiquitin and proteasome pathways
Cited by 364
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Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation
Powell, S. N., & Kachnic, L. A. (2003) · Oncogene
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 364
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Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair
Fleming, A. M., Ding, Y., & Burrows, C. J. (2017) · Proceedings of the National Academy of Sciences
DNA and Nucleic Acid ChemistryDNA Repair Mechanisms
Cited by 364
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Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding
Opie, S. R., Warrington, Agbandje-McKenna, M., Zolotukhin, S., & Muzyczka, N. (2003) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 364
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Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling
Muddashetty, R. S., Nalavadi, V. C., Gross, C., Yao, X., Xing, L., Laur, O., Warren, S. T., & Bassell, G. J. (2011) · Molecular Cell
Genetics and Neurodevelopmental DisordersMicroRNA in disease regulation
Cited by 364
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Nitric oxide-stimulated guanine nucleotide exchange on p21ras
Lander, H. M., Ogiste, J. S., Pearce, S. F. A., Levi, R., & Novogrodsky, A. (1995) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingNitric Oxide and Endothelin Effects
Cited by 364
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Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway
You, M., Yu, D.-H., & Feng, G.-S. (1999) · Molecular and Cellular Biology
Protein Tyrosine PhosphatasesCytokine Signaling Pathways and Interactions
Cited by 364
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Slug is a direct Notch target required for initiation of cardiac cushion cellularization
Niessen, K., Fu, Y., Chang, L., Hoodless, P. A., McFadden, D., & Karsan, A. (2008) · The Journal of Cell Biology
Developmental Biology and Gene RegulationCongenital heart defects research
Cited by 363
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Low Affinity Binding Site Clusters Confer Hox Specificity and Regulatory Robustness
Crocker, J., Abe, N., Rinaldi, L., McGregor, A. P., Frankel, N., Wang, S., Alsawadi, A., Valenti, P., Plaza, S., Payre, F., et al. (2015) · Cell
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 363
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Deeply conserved synteny resolves early events in vertebrate evolution
Simakov, O., Marlétaz, F., Yue, J.-X., O’Connell, B., Jenkins, J., Brandt, A., Calef, R., Tung, C.-H., Huang, T.-K., Schmutz, J., et al. (2020) · Nature Ecology & Evolution
Chromosomal and Genetic VariationsGenome Rearrangement Algorithms
Cited by 363
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Nicotine binding to brain receptors requires a strong cation–π interaction
Xiu, X., Puskar, N. L., Shanata, J. A. P., Lester, H. A., & Dougherty, D. A. (2009) · Nature
Nicotinic Acetylcholine Receptors StudyReceptor Mechanisms and Signaling
Cited by 363
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Type VIII adenylyl cyclase: a Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.
Cali, J. J., Zwaagstra, J. C., Mons, N., Cooper, D. M., & Krupinski, J. (1994) · Journal of Biological Chemistry
Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling
Cited by 363
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Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage
Kennedy, S. R., Salk, J. J., Schmitt, M. W., & Loeb, L. A. (2013) · PLoS Genetics
Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms
Cited by 363
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The effects of heavy resistance training and detraining on satellite cells in human skeletal muscles
Kadi, F., Schjerling, P., Andersen, L. L., Charifi, N., Madsen, J. L., Christensen, L. R., & Andersen, J. L. (2004) · The Journal of Physiology
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 363
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Two conserved histone demethylases regulate mitochondrial stress-induced longevity
Merkwirth, C., Jovaisaite, V., Durieux, J., Matilainen, O., Jordan, S. D., Quiros, P. M., Steffen, K. K., Williams, E. G., Mouchiroud, L., Tronnes, S. U., et al. (2016) · Cell
Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation
Cited by 363
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CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
Billon, P., Bryant, E. E., Joseph, S. A., Nambiar, T. S., Hayward, S. B., Rothstein, R., & Ciccia, A. (2017) · Molecular Cell
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 363
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Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA
Ellison, V., & Stillman, B. (2003) · PLoS Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 363
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Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
Moskvina, V, Craddock, N., Holmans, P., Nikolov, I., Pahwa, J. S., Green, E., Wellcome Trust Case Control Consortium, Owen, M. J., & O'Donovan, M. C. (2009) · Molecular Psychiatry
Genetic Associations and EpidemiologySchizophrenia research and treatment
Cited by 363
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