Most cited biochemistry, genetics and molecular biology papers
- Verified
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
Landt, S. G., Marinov, G. K., Kundaje, A., Kheradpour, P., Pauli, F., Batzoglou, S., Bernstein, B. E., Bickel, P., Brown, J. B., Cayting, P., et al. (2012) · Genome Research
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 2,033
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
The International Consortium for Blood Pressure Genome-Wide Association Studies (2011) · Nature
Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies
Cited by 2,033
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A census of human RNA-binding proteins
Gerstberger, S., Hafner, M., & Tuschl, T. (2014) · Nature Reviews Genetics
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 2,032
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Production of recombinant protein therapeutics in cultivated mammalian cells
Wurm, F. M. (2004) · Nature Biotechnology
Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability
Cited by 2,032
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Hyaluronan: its nature, distribution, functions and turnover.
Fraser, J. R. E., Laurent, T. C., & Laurent, U. B. G. (1997) · Journal of Internal Medicine
Proteoglycans and glycosaminoglycans researchHydrogels: synthesis, properties, applications
Cited by 2,031
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A tale of three next generation sequencing platforms: comparison of Ion torrent, pacific biosciences and illumina MiSeq sequencers
Quail, M., Smith, M. E., Coupland, P., Otto, T. D., Harris, S. R., Connor, T. R., Bertoni, A., Swerdlow, H. P., & Gu, Y. (2012) · BMC Genomics
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 2,031
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Targeted capture and massively parallel sequencing of 12 human exomes
Ng, S. B., Turner, E. H., Robertson, P. D., Flygare, S. D., Bigham, A. W., Lee, C., Shaffer, T., Wong, M., Bhattacharjee, A., Eichler, E. E., et al. (2009) · Nature
Genomics and Rare DiseasesGenomics and Phylogenetic Studies
Cited by 2,030
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Best practices for analysing microbiomes
Knight, R., Vrbanac, A., Taylor, B. C., Aksenov, A., Callewaert, C., Debelius, J., Gonzalez, A., Kosciolek, T., McCall, L.-I., McDonald, D., et al. (2018) · Nature Reviews Microbiology
Genomics and Phylogenetic StudiesGut microbiota and health
Cited by 2,030
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The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A.-P., et al. (2002) · Cell
Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer
Cited by 2,030
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Annexins: From Structure to Function
Gerke, V., & Moss, S. E. (2002) · Physiological Reviews
S100 Proteins and AnnexinsProtein Structure and Dynamics
Cited by 2,029
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Frequent pathway mutations of splicing machinery in myelodysplasia
Yoshida, K., Sanada, M., Shiraishi, Y., Nowak, D., Nagata, Y., Yamamoto, R., Sato, Y., Sato-Otsubo, A., Kon, A., Nagasaki, M., et al. (2011) · Nature
RNA Research and SplicingAcute Myeloid Leukemia Research
Cited by 2,029
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CRISPR–Cas9 Structures and Mechanisms
Jiang, F., & Doudna, J. A. (2017) · Annual Review of Biophysics
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 2,029
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Imaging individual mRNA molecules using multiple singly labeled probes
Raj, A., van den Bogaard, P., Rifkin, S. A., van Oudenaarden, A., & Tyagi, S. (2008) · Nature Methods
Advanced Fluorescence Microscopy TechniquesMolecular Biology Techniques and Applications
Cited by 2,028
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Photosynthesis under stressful environments: An overview
Ashraf, M., & Harris, P. J. C. (2013) · Photosynthetica
Photosynthetic Processes and MechanismsPlant Stress Responses and Tolerance
Cited by 2,028
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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
Kliewer, S. A., Lenhard, J. M., Willson, T. M., Patel, I., Morris, D. C., & Lehmann, J. M. (1995) · Cell
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 2,028
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Membrane Fusion: Grappling with SNARE and SM Proteins
Südhof, T. C., & Rothman, J. E. (2009) · Science
Cellular transport and secretionLipid Membrane Structure and Behavior
Cited by 2,027
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Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges
Fukumura, D., Kloepper, J., Amoozgar, Z., Duda, D. G., & Jain, R. K. (2018) · Nature Reviews Clinical Oncology
Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers
Cited by 2,027
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ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Jung, C. H., Jun, C. B., Ro, S.-H., Kim, Y.-M., Otto, N. M., Cao, J., Kundu, M., & Kim, D.-H. (2009) · Molecular Biology of the Cell
Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer
Cited by 2,025
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Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity
Markle, J. G. M., Frank, D. N., Mortin-Toth, S., Robertson, C. E., Feazel, L. M., Rolle-Kampczyk, U., von Bergen, M., McCoy, K. D., Macpherson, A. J., & Danska, J. S. (2013) · Science
Gut microbiota and healthDiabetes and associated disorders
Cited by 2,025
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NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Elinav, E., Strowig, T., Kau, A. L., Henao-Mejia, J., Thaiss, C. A., Booth, C. J., Peaper, D. R., Bertin, J., Eisenbarth, S. C., Gordon, J. I., et al. (2011) · Cell
Inflammasome and immune disordersInflammatory Bowel Disease
Cited by 2,024
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Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism
Zheng, P., Zeng, B., Zhou, C., Liu, M., Fang, Z., Xu, X., Zeng, L., Chen, J., Fan, S., Du, X., et al. (2016) · Molecular Psychiatry
Gut microbiota and healthTryptophan and brain disorders
Cited by 2,023
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DAMMIF , a program for rapid ab-initio shape determination in small-angle scattering
Franke, D., & Svergun, D. I. (2009) · Journal of Applied Crystallography
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 2,021
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Perk is essential for translational regulation and cell survival during the unfolded protein response
Harding, H. P., Zhang, Y., Bertolotti, A., Zeng, H., & Ron, D. (2000) · Molecular Cell
Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms
Cited by 2,021
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Activation of a metabolic gene regulatory network downstream of mTOR complex 1
Düvel, K., Yecies, J. L., Menon, S., Raman, P., Lipovsky, A. I., Souza, A. L., Triantafellow, E., Ma, Q., Gorski, R., Cleaver, S., et al. (2010) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 2,020
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