Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Nauli, S. M., Alenghat, F. J., Luo, Y., Williams, E., Vassilev, P., Li, X., Elia, A. E. H., Lu, W., Brown, E. M., Quinn, S. J., et al. (2003) · Nature Genetics

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 2,057

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

Purcell, S., Cherny, S. S., & Sham, P. C. (2003) · Bioinformatics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,057

The thioredoxin antioxidant system

Lu, J., & Holmgren, A. (2014) · Free Radical Biology and Medicine

Redox biology and oxidative stressSelenium in Biological Systems

Cited by 2,055

Oxidative damage and mitochondrial decay in aging.

Shigenaga, M. K., Hagen, T. M., & Ames, B. N. (1994) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 2,055

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

Watanabe, K., Ueno, M., Kamiya, D., Nishiyama, A., Matsumura, M., Wataya, T., Takahashi, J. B., Nishikawa, S., Nishikawa, S.-I., Muguruma, K., et al. (2007) · Nature Biotechnology

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 2,055

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

Chassaing, B., Koren, O., Goodrich, J. K., Poole, A. C., Srinivasan, S., Ley, R. E., & Gewirtz, A. T. (2015) · Nature

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 2,055

Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing

Xiao, W., Adhikari, S., Dahal, U., Chen, Y.-S., Hao, Y.-J., Sun, B.-F., Sun, H.-Y., Li, A., Ping, X.-L., Lai, W.-Y., et al. (2016) · Molecular Cell

RNA Research and SplicingRNA modifications and cancer

Cited by 2,054

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Jing, X., Yang, F., Shao, C., Wei, K., Xie, M., Shen, H., & Shu, Y. (2019) · Molecular Cancer

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

Cited by 2,054

KofamKOALA: KEGG ortholog assignment based on profile HMM and adaptive score threshold

Aramaki, T., Blanc-Mathieu, R., Endo, H., Ohkubo, K., Kanehisa, M., Goto, S., & Ogata, H. (2019) · Bioinformatics

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 2,054

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Brown, E. J., Albers, M. W., Bum Shin, T., ichikawa, K., Keith, C. T., Lane, W. S., & Schreiber, S. L. (1994) · Nature

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

Cited by 2,053

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Minokoshi, Y., Kim, Y.-B., Peroni, O. D., Fryer, L. G. D., Müller, C., Carling, D., & Kahn, B. B. (2002) · Nature

Metabolism, Diabetes, and CancerRegulation of Appetite and Obesity

Cited by 2,053

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Huarte, M., Guttman, M., Feldser, D., Garber, M., Koziol, M. J., Kenzelmann-Broz, D., Khalil, A. M., Zuk, O., Amit, I., Rabani, M., et al. (2010) · Cell

Cancer-related molecular mechanisms researchCancer-related Molecular Pathways

Cited by 2,053

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

Varadi, M., Bertoni, D., Magana, P., Paramval, U., Pidruchna, I., Radhakrishnan, M., Tsenkov, M., Nair, S., Mirdita, M., Yeo, J., et al. (2024) · Nucleic Acids Research

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 2,052

Persister cells, dormancy and infectious disease

Lewis, K. (2007) · Nature Reviews Microbiology

Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing

Cited by 2,052

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell

RNA Interference and Gene DeliveryMicroRNA in disease regulation

Cited by 2,052

Normalization of RNA-seq data using factor analysis of control genes or samples

Risso, D., Ngai, J., Speed, T. P., & Dudoit, S. (2014) · Nature Biotechnology

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 2,052

Phosphorylated CREB binds specifically to the nuclear protein CBP

Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature

Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 2,052

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

Viaud, S., Saccheri, F., Mignot, G., Yamazaki, T., Daillère, R., Hannani, D., Enot, D. P., Pfirschke, C., Engblom, C., Pittet, M. J., et al. (2013) · Science

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 2,050

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

Sender, R., Fuchs, S., & Milo, R. (2016) · Cell

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 2,050

The Fibroblast Growth Factor signaling pathway

Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology

Fibroblast Growth Factor ResearchDevelopmental Biology and Gene Regulation

Cited by 2,050

Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network

Ideker, T., Thorsson, V., Ranish, J. A., Christmas, R., Buhler, J., Eng, J. K., Bumgarner, R., Goodlett, D. R., Aebersold, R., & Hood, L. (2001) · Science

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 2,050

Biclustering algorithms for biological data analysis: a survey

Madeira, S. C., & Oliveira, A. L. (2004) · IEEE/ACM Transactions on Computational Biology and Bioinformatics

Gene expression and cancer classificationAdvanced Clustering Algorithms Research

Cited by 2,049

MicroRNAs in cancer: biomarkers, functions and therapy

Hayes, J., Peruzzi, P. P., & Lawler, S. (2014) · Trends in Molecular Medicine

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 2,049

Circulating endothelial progenitor cells and cardiovascular outcomes

Werner, N., Kosiol, S., Schiegl, T., Ahlers, P., Walenta, K., Link, A., Böhm, M., & Nickenig, G. (2005) · New England Journal of Medicine

Angiogenesis and VEGF in CancerMesenchymal stem cell research

Cited by 2,048