Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The expanded biology of serotonin

Berger, M., Gray, J. A., & Roth, B. L. (2009) · Annual Review of Medicine

Receptor Mechanisms and SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 2,100

Ferroptosis: machinery and regulation

Chen, X., Li, J., Kang, R., Klionsky, D. J., & Tang, D. (2021) · Autophagy

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 2,099

Antioxidant enzymes and human diseases

MatÉs, J. M., Pérez-Gómez, C., & De Castro, I. N. (1999) · Clinical Biochemistry

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,099

RNA-programmed genome editing in human cells

Jinek, M., East, A., Cheng, A., Lin, S., Ma, E., & Doudna, J. (2013) · eLife

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,098

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., & Bonner, W. M. (2000) · Current Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 2,098

A TALE nuclease architecture for efficient genome editing

Miller, J. C., Tan, S., Qiao, G., Barlow, K. A., Wang, J., Xia, D. F., Meng, X., Paschon, D. E., Leung, E., Hinkley, S. J., et al. (2011) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,098

X-inactivation profile reveals extensive variability in X-linked gene expression in females

Carrel, L., & Willard, H. F. (2005) · Nature

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 2,097

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B., & Bacchetti, S. (1992) · The EMBO Journal

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,096

Ridge Regression and Other Kernels for Genomic Selection with R Package rrBLUP

Endelman, J. B. (2011) · The Plant Genome

Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals

Cited by 2,094

Rational siRNA design for RNA interference

Reynolds, A., Leake, D., Boese, Q., Scaringe, S., Marshall, W. S., & Khvorova, A. (2004) · Nature Biotechnology

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 2,094

TNF-mediated inflammatory disease

Bradley, Jr. (2008) · The Journal of Pathology

NF-κB Signaling PathwaysRheumatoid Arthritis Research and Therapies

Cited by 2,094

Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

Derrien, M., Vaughan, E. E., Plugge, C. M., & de Vos, W. M. (2004) · International Journal of Systematic and Evolutionary Microbiology

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 2,094

WNT signaling in bone homeostasis and disease: From human mutations to treatments

Baron, R., & Kneissel, M. (2013) · Nature Medicine

Wnt/β-catenin signaling in development and cancerBone health and osteoporosis research

Cited by 2,093

RNA targeting with CRISPR–Cas13

Abudayyeh, O. O., Gootenberg, J. S., Essletzbichler, P., Han, S., Joung, J., Belanto, J. J., Verdine, V., Cox, D. B. T., Kellner, M. J., Regev, A., et al. (2017) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,093

Cellular mechanisms and physiological consequences of redox-dependent signalling

Holmström, K. M., & Finkel, T. (2014) · Nature Reviews Molecular Cell Biology

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,093

Adaptation from standing genetic variation

BARRETT, R., & SCHLUTER, D. (2008) · Trends in Ecology & Evolution

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 2,091

mTOR regulation of autophagy

Jung, C. H., Ro, S.-H., Cao, J., Otto, N. M., & Kim, D.-H. (2010) · FEBS Letters

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 2,090

A Landscape of Pharmacogenomic Interactions in Cancer

Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N., Gonçalves, E., Barthorpe, S., Lightfoot, H., et al. (2016) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 2,090

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

Jessell, T. M. (2000) · Nature Reviews Genetics

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 2,089

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Dixon, S. J., Patel, D. N., Welsch, M., Skouta, R., Lee, E. D., Hayano, M., Thomas, A. G., Gleason, C. E., Tatonetti, N. P., Slusher, B. S., et al. (2014) · eLife

Ferroptosis and cancer prognosisAmino Acid Enzymes and Metabolism

Cited by 2,088

Protein degradation and protection against misfolded or damaged proteins.

Goldberg, A. L. (2003) · Nature

Ubiquitin and proteasome pathwaysHeat shock proteins research

Cited by 2,088

Systematic variation in gene expression patterns in human cancer cell lines

Ross, D. T., Scherf, U., Eisen, M. B., Perou, C. M., Rees, C., Spellman, P., Iyer, V., Jeffrey, S. S., Van de Rijn, M., Waltham, M., et al. (2000) · Nature Genetics

Gene expression and cancer classificationBreast Cancer Treatment Studies

Cited by 2,088

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

Franceschi, C., Capri, M., Monti, D., Giunta, S., Olivieri, F., Sevini, F., Panourgia, M. P., Invidia, L., Celani, L., Scurti, M., et al. (2007) · Mechanisms of Ageing and Development

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 2,087

The Mammalian Epigenome

Bernstein, B. E., Meissner, A., & Lander, E. S. (2007) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,086