Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 2,019

Ras, PI(3)K and mTOR signalling controls tumour cell growth

Shaw, R. J., & Cantley, L. C. (2006) · Nature

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,019

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

Burgess, S., Bowden, J., Fall, T., Ingelsson, E., & Thompson, S. G. (2017) · Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 2,017

PPARγ signaling and metabolism: the good, the bad and the future

Ahmadian, M., Suh, J. M., Hah, N., Liddle, C., Atkins, A. R., Downes, M., & Evans, R. M. (2013) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 2,016

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

Lavelle, A., & Sokol, H. (2020) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 2,015

Melanin pigmentation in mammalian skin and its hormonal regulation

Slominski, A., Tobin, D. J., Shibahara, S., & Wortsman, J. (2004) · Physiological Reviews

melanin and skin pigmentationMelanoma and MAPK Pathways

Cited by 2,015

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

Kato, M., Han, T. W., Xie, S., Shi, K., Du, X., Wu, L. C., Mirzaei, H., Goldsmith, E. J., Longgood, J., Pei, J., et al. (2012) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,012

The microbiome and innate immunity

Thaiss, C. A., Zmora, N., Levy, M., & Elinav, E. (2016) · Nature

Gut microbiota and healthImmune Response and Inflammation

Cited by 2,012

Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Sun, X., Ou, Z., Chen, R., Niu, X., Chen, D., Kang, R., & Tang, D. (2016) · Hepatology

Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress

Cited by 2,012

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., et al. (1996) · Nature

Advanced Glycation End Products researchAlzheimer's disease research and treatments

Cited by 2,012

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

O’Mahony, S. M., Clarke, G., Borre, Y. E., Dinan, T. G., & Cryan, J. F. (2015) · Behavioural Brain Research

Gut microbiota and healthTryptophan and brain disorders

Cited by 2,012

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Viswanathan, V. S., Ryan, M. J., Dhruv, H. D., Gill, S., Eichhoff, O. M., Seashore-Ludlow, B., Kaffenberger, S. D., Eaton, J. K., Shimada, K., Aguirre, A. J., et al. (2017) · Nature

Ferroptosis and cancer prognosisCancer, Lipids, and Metabolism

Cited by 2,011

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the “phosphocreatine circuit” for cellular energy homeostasis

Wallimann, T., Wyss, M., Brdiczka, D., Nicolay, K., & Eppenberger, H. M. (1992) · Biochemical Journal

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 2,011

From endoplasmic-reticulum stress to the inflammatory response

Zhang, K., & Kaufman, R. J. (2008) · Nature

Endoplasmic Reticulum Stress and DiseaseIon Channels and Receptors

Cited by 2,010

Evolution of genes and genomes on the Drosophila phylogeny

Drosophila 12 Genomes Consortium (2007) · Nature

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 2,010

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

Chang, T.-C., Wentzel, E. A., Kent, O. A., Ramachandran, K., Mullendore, M., Lee, K. H., Feldmann, G., Yamakuchi, M., Ferlito, M., Lowenstein, C. J., et al. (2007) · Molecular Cell

MicroRNA in disease regulationCancer-related Molecular Pathways

Cited by 2,010

PANTHER : Making genome‐scale phylogenetics accessible to all

Thomas, P. D., Ebert, D., Muruganujan, A., Mushayahama, T., Albou, L., & Mi, H. (2022) · Protein Science

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 2,010

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Gorgoulis, V. G., Vassiliou, L.-V. F., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., Venere, M., DiTullio, R. A., Kastrinakis, N. G., Levy, B., et al. (2005) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,009

Exosomes as drug delivery vehicles for Parkinson’s disease therapy

Haney, M. J., Klyachko, N. L., Zhao, Y., Gupta, R., Plotnikova, E. G., He, Z., Patel, T., Piroyan, A., Sokolsky, M., Kabanov, A. V., et al. (2015) · Journal of Controlled Release

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 2,009

Mesenchymal stem cell perspective: cell biology to clinical progress

Pittenger, M. F., Discher, D. E., Péault, B. M., Phinney, D. G., Hare, J. M., & Caplan, A. I. (2019) · npj Regenerative Medicine

Mesenchymal stem cell researchPeriodontal Regeneration and Treatments

Cited by 2,008

Structural and molecular interrogation of intact biological systems

Chung, K., Wallace, J., Kim, S.-Y., Kalyanasundaram, S., Andalman, A. S., Davidson, T. J., Mirzabekov, J. J., Zalocusky, K. A., Mattis, J., Denisin, A. K., et al. (2013) · Nature

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 2,008

The role of dynamic conformational ensembles in biomolecular recognition

Boehr, D. D., Nussinov, R., & Wright, P. E. (2009) · Nature Chemical Biology

Protein Structure and DynamicsReceptor Mechanisms and Signaling

Cited by 2,008

Formation of chromosomal domains by loop extrusion

Fudenberg, G., Imakaev, M., Lu, C., Goloborodko, A., Abdennur, N., & Mirny, L. A. (2016) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 2,003

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

Becker, A., Thakur, B. K., Weiss, J. M., Kim, H. S., Peinado, H., & Lyden, D. (2016) · Cancer Cell

Extracellular vesicles in diseaseCancer Cells and Metastasis

Cited by 2,003