Most cited biochemistry, genetics and molecular biology papers
- Verified
New families in the classification of glycosyl hydrolases based on amino acid sequence similarities
Henrissat, B., & Bairoch, A. (1993) · Biochemical Journal
Enzyme Production and CharacterizationGenomics and Phylogenetic Studies
Cited by 1,974
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Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap
Reimand, J., Isserlin, R., Voisin, V., Kucera, M., Tannus-Lopes, C., Rostamianfar, A., Wadi, L., Meyer, M., Wong, J., Xu, C., et al. (2019) · Nature Protocols
Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies
Cited by 1,970
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YAP/TAZ at the Roots of Cancer
Zanconato, F., Cordenonsi, M., & Piccolo, S. (2016) · Cancer Cell
Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics
Cited by 1,970
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Origins and functional impact of copy number variation in the human genome
The Wellcome Trust Case Control Consortium, Conrad, D. F., Pinto, D., Redon, R., Feuk, L., Gokcumen, O., Zhang, Y., Aerts, J., Andrews, T. D., Barnes, C., et al. (2010) · Nature
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 1,970
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The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis
Yamamoto, M., Kensler, T. W., & Motohashi, H. (2018) · Physiological Reviews
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 1,968
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Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
Hwang, C., Sinskey, A. J., & Lodish, H. F. (1992) · Science
Redox biology and oxidative stressSulfur Compounds in Biology
Cited by 1,968
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The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Shah, S. P., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., et al. (2012) · Nature
Cancer Genomics and DiagnosticsBreast Cancer Treatment Studies
Cited by 1,967
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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., & Karlsson, S. (1993) · Proceedings of the National Academy of Sciences
TGF-β signaling in diseasesT-cell and B-cell Immunology
Cited by 1,967
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Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., et al. (2009) · Nature Methods
Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research
Cited by 1,967
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Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid
Breitman, T. R., Selonick, S. E., & Collins, S. J. (1980) · Proceedings of the National Academy of Sciences
Retinoids in leukemia and cellular processesAcute Myeloid Leukemia Research
Cited by 1,966
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Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype
Jaillon, O., Aury, J.-M., Brunet, F., Petit, J.-L., Stange-Thomann, N., Mauceli, E., Bouneau, L., Fischer, C., Ozouf-Costaz, C., Bernot, A., et al. (2004) · Nature
Chromosomal and Genetic VariationsGenome Rearrangement Algorithms
Cited by 1,966
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Cell cycle checkpoint signaling through the ATM and ATR kinases
Abraham, R. T. (2001) · Genes & Development
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,966
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Identification of a receptor for the morphogen retinoic acid
Giguere, V., Ong, E. S., Segui, P., & Evans, R. M. (1987) · Nature
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 1,965
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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., et al. (1995) · Science
Estrogen and related hormone effectsProtein Kinase Regulation and GTPase Signaling
Cited by 1,964
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AACR Project GENIE: Powering Precision Medicine through an International Consortium
The AACR Project GENIE Consortium, The AACR Project GENIE Consortium, André, F., Arnedos, M., Baras, A. S., Baselga, J., Bedard, P. L., Berger, M. F., Bierkens, M., Calvo, F., et al. (2017) · Cancer Discovery
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 1,964
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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.
Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell
Muscle Physiology and DisordersFOXO transcription factor regulation
Cited by 1,964
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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase
Baekkeskov, S., Aanstoot, H.-J., Christgai, S., Reetz, A., Solimena, M., Cascalho, M., Folli, F., Richter-Olesen, H., & Camilli, P.-D. (1990) · Nature
Diabetes and associated disordersAutoimmune Neurological Disorders and Treatments
Cited by 1,964
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The neuroactive potential of the human gut microbiota in quality of life and depression
Valles-Colomer, M., Falony, G., Darzi, Y., Tigchelaar, E. F., Wang, J., Tito, R. Y., Schiweck, C., Kurilshikov, A., Joossens, M., Wijmenga, C., et al. (2019) · Nature Microbiology
Gut microbiota and healthTryptophan and brain disorders
Cited by 1,963
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Stability and flexibility of epigenetic gene regulation in mammalian development
Reik, W. (2007) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,963
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Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
Kostic, A. D., Gevers, D., Pedamallu, C. S., Michaud, M., Duke, F., Earl, A. M., Ojesina, A. I., Jung, J., Bass, A. J., Tabernero, J., et al. (2012) · Genome Research
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,960
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A codon-based model of nucleotide substitution for protein-coding DNA sequences.
Goldman, N., & Yang, Z. (1994) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms
Cited by 1,960
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Exome sequencing identifies the cause of a mendelian disorder
Ng, S. B., Buckingham, K. J., Lee, C., Bigham, A. W., Tabor, H. K., Dent, K. M., Huff, C. D., Shannon, P. T., Jabs, E. W., Nickerson, D. A., et al. (2010) · Nature Genetics
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 1,957
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Roles of PPARs in health and disease
Kersten, S., Desvergne, B., & Wahli, W. (2000) · Nature
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 1,956
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The Essential Medicinal Chemistry of Curcumin
Nelson, K. M., Dahlin, J. L., Bisson, J., Graham, J., Pauli, G. F., & Walters, M. A. (2017) · Journal of Medicinal Chemistry
Curcumin's Biomedical ApplicationsBioactive natural compounds
Cited by 1,956
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