Most cited biochemistry, genetics and molecular biology papers
- Verified
Mammalian autophagy: core molecular machinery and signaling regulation
Yang, Z., & Klionsky, D. J. (2010) · Current Opinion in Cell Biology
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 1,956
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Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
Caplan, A. I. (2007) · Journal of Cellular Physiology
Mesenchymal stem cell researchPeriodontal Regeneration and Treatments
Cited by 1,956
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Genetic and epigenetic fine mapping of causal autoimmune disease variants
Farh, K. K.-H., Marson, A., Zhu, J., Kleinewietfeld, M., Housley, W. J., Beik, S., Shoresh, N., Whitton, H., Ryan, R. J. H., Shishkin, A. A., et al. (2015) · Nature
Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics
Cited by 1,956
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Phosphatidylinositol-3-OH kinase direct target of Ras
Rodriguez-Viciana, P., Warne, P. H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M. J., Waterfield, M. D., & Downward, J. (1994) · Nature
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer
Cited by 1,954
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Changes in the Levels of Inositol Phosphates after Agonist-Dependent Hydrolysis of Membrane Phosphoinositides
Berridge, M. J., Dawson, R. M. C., Downes, C. P., Heslop, J. P., & Irvine, R. F. (1983) · Biochemical Journal
Protein Kinase Regulation and GTPase SignalingLipid metabolism and biosynthesis
Cited by 1,954
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Lipid peroxidation and ferroptosis: The role of GSH and GPx4
Ursini, F., & Maiorino, M. (2020) · Free Radical Biology and Medicine
Ferroptosis and cancer prognosisSelenium in Biological Systems
Cited by 1,954
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ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks
Burma, S., Chen, B. P., Murphy, M., Kurimasa, A., & Chen, D. J. (2001) · Journal of Biological Chemistry
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 1,954
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Regulation of circRNA biogenesis
Chen, L.-L., & Yang, L. (2015) · RNA Biology
Circular RNAs in diseasesRNA Research and Splicing
Cited by 1,953
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FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
Mammucari, C., Milan, G., Romanello, V., Masiero, E., Rudolf, R., Del Piccolo, P., Burden, S. J., Di Lisi, R., Sandri, C., Zhao, J., et al. (2007) · Cell Metabolism
Autophagy in Disease and TherapyMuscle Physiology and Disorders
Cited by 1,953
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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
Patti, M. E., Butte, A. J., Crunkhorn, S., Cusi, K., Berria, R., Kashyap, S., Miyazaki, Y., Kohane, I., Costello, M., Saccone, R., et al. (2003) · Proceedings of the National Academy of Sciences
Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism
Cited by 1,952
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Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
Meyers, R. M., Bryan, J. G., McFarland, J. M., Weir, B. A., Sizemore, A. E., Xu, H., Dharia, N. V., Montgomery, P. G., Cowley, G. S., Pantel, S., et al. (2017) · Nature Genetics
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 1,952
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Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
Snippert, H. J., van der Flier, L. G., Sato, T., van Es, J. H., van den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., van Rheenen, J., Simons, B. D., et al. (2010) · Cell
Developmental Biology and Gene RegulationCancer Cells and Metastasis
Cited by 1,951
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Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
Giesen, C., Wang, H. A. O., Schapiro, D., Zivanovic, N., Jacobs, A., Hattendorf, B., Schüffler, P. J., Grolimund, D., Buhmann, J. M., Brandt, S., et al. (2014) · Nature Methods
Single-cell and spatial transcriptomicsMass Spectrometry Techniques and Applications
Cited by 1,951
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pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest
Hannon, G. J., & Beach, D. (1994) · Nature
TGF-β signaling in diseasesCancer-related Molecular Pathways
Cited by 1,950
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The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota
Milani, C., Duranti, S., Bottacini, F., Casey, E., Turroni, F., Mahony, J., Belzer, C., Delgado Palacio, S., Arboleya Montes, S., Mancabelli, L., et al. (2017) · Microbiology and Molecular Biology Reviews
Gut microbiota and healthInfant Nutrition and Health
Cited by 1,950
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Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.
Excoffier, L., & Slatkin, M. (1995) · Molecular Biology and Evolution
Genetic diversity and population structureForensic and Genetic Research
Cited by 1,950
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The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
Shaw, R. J., Lamia, K. A., Vasquez, D., Koo, S.-H., Bardeesy, N., DePinho, R. A., Montminy, M., & Cantley, L. C. (2005) · Science
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 1,950
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The complex role of estrogens in inflammation
Straub, R. H. (2007) · Endocrine Reviews
Estrogen and related hormone effectsInflammatory mediators and NSAID effects
Cited by 1,950
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AU-rich elements: characterization and importance in mRNA degradation
Chen, C.-Y. A., & Shyu, A.-B. (1995) · Trends in Biochemical Sciences
RNA Research and SplicingRNA regulation and disease
Cited by 1,948
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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
Dinkova-Kostova, A. T., Holtzclaw, W. D., Cole, R. N., Itoh, K., Wakabayashi, N., Katoh, Y., Yamamoto, M., & Talalay, P. (2002) · Proceedings of the National Academy of Sciences
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 1,947
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Guide to receptors and channels (GRAC), 5th edition
Alexander, S., Mathie, A., & Peters, J. (2011) · British Journal of Pharmacology
Receptor Mechanisms and SignalingIon channel regulation and function
Cited by 1,947
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Inhibitory effect of tumor cell-derived lactic acid on human T cells
Fischer, K., Hoffmann, P., Voelkl, S., Meidenbauer, N., Ammer, J., Edinger, M., Gottfried, E., Schwarz, S., Rothe, G., Hoves, S., et al. (2007) · Blood
Cancer, Hypoxia, and MetabolismImmune cells in cancer
Cited by 1,946
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Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
Atsumi, S., Hanai, T., & Liao, J. C. (2008) · Nature
Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversion
Cited by 1,945
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The FGF family: biology, pathophysiology and therapy
Beenken, A., & Mohammadi, M. (2009) · Nature Reviews Drug Discovery
Fibroblast Growth Factor ResearchConnective Tissue Growth Factor Research
Cited by 1,945
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