Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., et al. (2010) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 1,945

Crystal structure of the ribosome at 5.5 Å resolution

Yusupov, M. M., Yusupova, G. Z., Baucom, A., Lieberman, K., Earnest, T. N., Cate, J. H. D., & Noller, H. F. (2001) · Science

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 1,944

Iron-sulfur clusters: nature's modular, multipurpose structures

Beinert, H., Holm, R. H., & Münck, E. (1997) · Science

Metalloenzymes and iron-sulfur proteinsInorganic Chemistry and Materials

Cited by 1,944

RAS Proteins and Their Regulators in Human Disease

Simanshu, D. K., Nissley, D. V., & McCormick, F. (2017) · Cell

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 1,943

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

Shackelford, D. B., & Shaw, R. J. (2009) · Nature Reviews Cancer

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 1,943

Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

Khera, A. V., Cuchel, M., de la Llera-Moya, M., Rodrigues, A., Burke, M. F., Jafri, K., French, B. C., Phillips, J. A., Mucksavage, M. L., Wilensky, R. L., et al. (2011) · New England Journal of Medicine

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 1,943

Analysis of composition of microbiomes: a novel method for studying microbial composition

Mandal, S., Van Treuren, W., White, R. A., Eggesbø, M., Knight, R., & Peddada, S. D. (2015) · Microbial Ecology in Health & Disease

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,942

Crosstalk in NF-κB Signaling Pathways

Oeckinghaus, A., Hayden, M. S., & Ghosh, S. (2011) · Nature Immunology

NF-κB Signaling PathwaysSignaling Pathways in Disease

Cited by 1,942

Structural Basis of the Drug-binding Specificity of Human Serum Albumin

Ghuman, J., Zunszain, P. A., Petitpas, I., Bhattacharya, A. A., Otagiri, M., & Curry, S. (2005) · Journal of Molecular Biology

Protein Interaction Studies and Fluorescence AnalysisProtein Structure and Dynamics

Cited by 1,941

Characterization of extracellular circulating microRNA

Turchinovich, A., Weiz, L., Langheinz, A., & Burwinkel, B. (2011) · Nucleic Acids Research

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 1,941

ROCKs: multifunctional kinases in cell behaviour

Riento, K., & Ridley, A. J. (2003) · Nature Reviews Molecular Cell Biology

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 1,941

RNAhybrid: microRNA target prediction easy, fast and flexible

Kruger, J., & Rehmsmeier, M. (2006) · Nucleic Acids Research

MicroRNA in disease regulationRNA and protein synthesis mechanisms

Cited by 1,941

Massive migration from the steppe was a source for Indo-European languages in Europe

Haak, W., Lazaridis, I., Patterson, N., Rohland, N., Mallick, S., Llamas, B., Brandt, G., Nordenfelt, S., Harney, E., Stewardson, K., et al. (2015) · Nature

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 1,940

Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,939

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A., & Connelly, P. A. (1996) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingT-cell and B-cell Immunology

Cited by 1,939

Regulation of short-chain fatty acid production

Macfarlane, S., & Macfarlane, G. T. (2003) · Proceedings of the Nutrition Society

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 1,939

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

Liu, Z.-G., Hsu, H., Goeddel, D. V., & Karin, M. (1996) · Cell

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 1,937

The 2017 international classification of the Ehlers–Danlos syndromes

Malfait, F., Francomano, C., Byers, P., Belmont, J., Berglund, B., Black, J., Bloom, L., Bowen, J. M., Brady, A. F., Burrows, N. P., et al. (2017) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics

Connective tissue disorders researchGenomics and Rare Diseases

Cited by 1,936

Suppression of Aging in Mice by the Hormone Klotho

Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science

Genetics, Aging, and Longevity in Model OrganismsParathyroid Disorders and Treatments

Cited by 1,935

JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles

Castro-Mondragon, J. A., Riudavets-Puig, R., Rauluseviciute, I., Berhanu Lemma, R., Turchi, L., Blanc-Mathieu, R., Lucas, J., Boddie, P., Khan, A., Manosalva Pérez, N., et al. (2022) · Nucleic Acids Research

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 1,935

The multifaceted contributions of mitochondria to cellular metabolism

Spinelli, J. B., & Haigis, M. C. (2018) · Nature Cell Biology

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,935

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

Kosaka, N., Iguchi, H., Yoshioka, Y., Takeshita, F., Matsuki, Y., & Ochiya, T. (2010) · Journal of Biological Chemistry

Extracellular vesicles in diseaseMicroRNA in disease regulation

Cited by 1,934

The economics of ribosome biosynthesis in yeast

Warner, J. R. (1999) · Trends in Biochemical Sciences

Fungal and yeast genetics researchRNA and protein synthesis mechanisms

Cited by 1,933

Rates of spontaneous mutation

Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics

Evolution and Genetic DynamicsChromosomal and Genetic Variations

Cited by 1,932