Most cited biochemistry, genetics and molecular biology papers
- Verified
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Zhang, D.-W., Shao, J., Lin, J., Zhang, N., Lu, B.-J., Lin, S.-C., Dong, M.-Q., & Han, J. (2009) · Science
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 1,931
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Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Dao, M. C., Everard, A., Aron-Wisnewsky, J., Sokolovska, N., Prifti, E., Verger, E. O., Kayser, B. D., Levenez, F., Chilloux, J., Hoyles, L., et al. (2016) · Gut
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 1,931
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Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis
Leek, J. T., & Storey, J. D. (2007) · PLoS Genetics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 1,930
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Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
Karikó, K., Muramatsu, H., Welsh, F. A., Ludwig, J., Kato, H., Akira, S., & Weissman, D. (2008) · Molecular Therapy
RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms
Cited by 1,930
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Epigenetics and the environment: emerging patterns and implications
Feil, R., & Fraga, M. F. (2012) · Nature Reviews Genetics
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 1,929
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UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches
Suzek, B. E., Wang, Y., Huang, H., McGarvey, P. B., Wu, C. H., & the UniProt Consortium (2015) · Bioinformatics
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 1,928
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Variation in cancer risk among tissues can be explained by the number of stem cell divisions
Tomasetti, C., & Vogelstein, B. (2015) · Science
Cancer Genomics and DiagnosticsEvolution and Genetic Dynamics
Cited by 1,927
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The functions and regulation of the PTEN tumour suppressor
Song, M. S., Salmena, L., & Pandolfi, P. P. (2012) · Nature Reviews Molecular Cell Biology
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,926
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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
Chandel, N. S., Maltepe, E., Goldwasser, E., Mathieu, C. E., Simon, M. C., & Schumacker, P. T. (1998) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress
Cited by 1,926
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Ancient DNA and the rewriting of human history: be sparing with Occam’s razor
Haber, M., Mezzavilla, M., Xue, Y., & Tyler-Smith, C. (2016) · Genome Biology
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 1,924
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Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
Jia, W., Xie, G., & Jia, W. (2018) · Nature Reviews Gastroenterology & Hepatology
Gut microbiota and healthDrug Transport and Resistance Mechanisms
Cited by 1,924
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Analysis of shared heritability in common disorders of the brain
The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,924
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Ensembl 2022
Cunningham, F., Allen, J. E., Allen, J., Alvarez-Jarreta, J., Amode, M. R., Armean, I. M., Austine-Orimoloye, O., Azov, A. G., Barnes, I., Bennett, R., et al. (2022) · Nucleic Acids Research
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 1,923
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Atomic-level characterization of the structural dynamics of proteins
Shaw, D. E., Maragakis, P., Lindorff-Larsen, K., Piana, S., Dror, R. O., Eastwood, M. P., Bank, J. A., Jumper, J. M., Salmon, J. K., Shan, Y., et al. (2010) · Science
Protein Structure and DynamicsRNA and protein synthesis mechanisms
Cited by 1,923
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COSMIC: somatic cancer genetics at high-resolution
Forbes, S. A., Beare, D., Boutselakis, H., Bamford, S., Bindal, N., Tate, J., Cole, C. G., Ward, S., Dawson, E., Ponting, L., et al. (2017) · Nucleic Acids Research
Cancer Genomics and DiagnosticsGenomics and Rare Diseases
Cited by 1,922
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Polygenic prediction via Bayesian regression and continuous shrinkage priors
Ge, T., Chen, C.-Y., Ni, Y., Feng, Y.-C. A., & Smoller, J. W. (2019) · Nature Communications
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 1,922
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Mobile Elements: Drivers of Genome Evolution
Kazazian, H. H. (2004) · Science
Chromosomal and Genetic VariationsGenome Rearrangement Algorithms
Cited by 1,922
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Heritability in the genomics era — concepts and misconceptions
Visscher, P. M., Hill, W. G., & Wray, N. R. (2008) · Nature Reviews Genetics
Genetic and phenotypic traits in livestockGenetic Associations and Epidemiology
Cited by 1,921
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Broad phylogenomic sampling improves resolution of the animal tree of life
Dunn, C. W., Hejnol, A., Matus, D. Q., Pang, K., Browne, W. E., Smith, S. A., Seaver, E., Rouse, G. W., Obst, M., Edgecombe, G. D., et al. (2008) · Nature
Genomics and Phylogenetic StudiesInvertebrate Taxonomy and Ecology
Cited by 1,921
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Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Wen, L., Ley, R. E., Volchkov, P. Y., Stranges, P. B., Avanesyan, L., Stonebraker, A. C., Hu, C., Wong, F. S., Szot, G. L., Bluestone, J. A., et al. (2008) · Nature
Diabetes and associated disordersGut microbiota and health
Cited by 1,921
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Autophagy in infection, inflammation and immunity
Deretic, V., Saitoh, T., & Akira, S. (2013) · Nature Reviews Immunology
Autophagy in Disease and TherapyImmune Response and Inflammation
Cited by 1,919
- Verified
The aging process
Harman, D. (1981) · Proceedings of the National Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsAntioxidant Activity and Oxidative Stress
Cited by 1,915
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Programmed Cell Death in Animal Development and Disease
Fuchs, Y., & Steller, H. (2011) · Cell
Cell death mechanisms and regulationPhagocytosis and Immune Regulation
Cited by 1,915
- Verified
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
Zhernakova, A., Kurilshikov, A., Bonder, M. J., Tigchelaar, E. F., Schirmer, M., Vatanen, T., Mujagic, Z., Vila, A. V., Falony, G., Vieira-Silva, S., et al. (2016) · Science
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,914
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