Most cited biochemistry, genetics and molecular biology papers
- Verified
Regulation of Mammalian O 2 Homeostasis by Hypoxia-Inducible Factor 1
Semenza, G. L. (1999) · Annual Review of Cell and Developmental Biology
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,914
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segrè, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, H., Grallert, H., et al. (2012) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,912
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Pleiotropy, natural selection, and the evolution of senescence
Williams, G. C. (1957) · Evolution
Evolution and Genetic DynamicsGenetics, Aging, and Longevity in Model Organisms
Cited by 1,912
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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
Inoki, K., Li, Y., Xu, T., & Guan, K.-L. (2003) · Genes & Development
PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research
Cited by 1,911
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Regulation of cellular metabolism by protein lysine acetylation
Zhao, S., Xu, W., Jiang, W., Yu, W., Lin, Y., Zhang, T., Yao, J., Zhou, L., Zeng, Y., Li, H., et al. (2010) · Science
Biochemical Acid Research StudiesCancer-related gene regulation
Cited by 1,910
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Direct observation of kinesin stepping by optical trapping interferometry
Svoboda, K., Schmidt, C. F., Schnapp, B. J., & Block, S. M. (1993) · Nature
Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications
Cited by 1,910
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Mutational Processes Molding the Genomes of 21 Breast Cancers
Nik-Zainal, S., Alexandrov, L. B., Wedge, D. C., Van Loo, P., Greenman, C. D., Raine, K., Jones, D., Hinton, J., Marshall, J., Stebbings, L. A., et al. (2012) · Cell
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 1,909
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Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D. L., Fire, A., Ruvkun, G., & Mello, C. C. (2001) · Cell
RNA Interference and Gene DeliveryPlant Molecular Biology Research
Cited by 1,908
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Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data
Gutenkunst, R. N., Hernandez, R. D., Williamson, S. H., & Bustamante, C. D. (2009) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 1,906
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r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock
Sanderson, M. J. (2003) · Bioinformatics
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 1,906
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Extensive impact of non-antibiotic drugs on human gut bacteria
Maier, L., Pruteanu, M., Kuhn, M., Zeller, G., Telzerow, A., Anderson, E. E., Brochado, A. R., Fernandez, K. C., Dose, H., Mori, H., et al. (2018) · Nature
Gut microbiota and healthAntibiotic Resistance in Bacteria
Cited by 1,905
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A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
Machiels, K., Joossens, M., Sabino, J., De Preter, V., Arijs, I., Eeckhaut, V., Ballet, V., Claes, K., Van Immerseel, F., Verbeke, K., et al. (2014) · Gut
Gut microbiota and healthInflammatory Bowel Disease
Cited by 1,904
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Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice
Devkota, S., Wang, Y., Musch, M. W., Leone, V., Fehlner-Peach, H., Nadimpalli, A., Antonopoulos, D. A., Jabri, B., & Chang, E. B. (2012) · Nature
Gut microbiota and healthInflammatory Bowel Disease
Cited by 1,904
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GEFs and GAPs: Critical Elements in the Control of Small G Proteins
Bos, J. L., Rehmann, H., & Wittinghofer, A. (2007) · Cell
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 1,903
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Improving photosynthetic efficiency for greater yield.
Zhu, X.-G., Long, S. P., & Ort, D. R. (2010) · Annual Review of Plant Biology
Photosynthetic Processes and MechanismsCrop Yield and Soil Fertility
Cited by 1,902
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Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
Tan, M., Luo, H., Lee, S., Jin, F., Yang, J. S., Montellier, E., Buchou, T., Cheng, Z., Rousseaux, S., Rajagopal, N., et al. (2011) · Cell
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,902
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RAS oncogenes: the first 30 years
Malumbres, M., & Barbacid, M. (2003) · Nature Reviews Cancer
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 1,902
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Whole-genome analyses resolve early branches in the tree of life of modern birds
Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., Ho, S. Y. W., Faircloth, B. C., Nabholz, B., Howard, J. T., et al. (2014) · Science
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 1,901
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Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S., & Hirschhorn, J. N. (2003) · Nature Genetics
Genetic Associations and EpidemiologyMeta-analysis and systematic reviews
Cited by 1,900
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The pathways of mitophagy for quality control and clearance of mitochondria
Ashrafi, G., & Schwarz, T. L. (2013) · Cell Death & Differentiation
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 1,900
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Interactions between the microbiota, immune and nervous systems in health and disease
Fung, T. C., Olson, C. A., & Hsiao, E. Y. (2017) · Nature Neuroscience
Gut microbiota and healthTryptophan and brain disorders
Cited by 1,900
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Chromatin modification and epigenetic reprogramming in mammalian development
Li, E. (2002) · Nature Reviews Genetics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,900
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Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
Baietti, M. F., Zhang, Z., Mortier, E., Melchior, A., Degeest, G., Geeraerts, A., Ivarsson, Y., Depoortere, F., Coomans, C., Vermeiren, E., et al. (2012) · Nature Cell Biology
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 1,899
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Ferroptosis is an autophagic cell death process
Gao, M., Monian, P., Pan, Q., Zhang, W., Xiang, J., & Jiang, X. (2016) · Cell Research
Ferroptosis and cancer prognosisAutophagy in Disease and Therapy
Cited by 1,899
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