Most cited biochemistry, genetics and molecular biology papers
- Verified
Multiscale Modeling of Biological Functions: From Enzymes to Molecular Machines (Nobel Lecture)
Warshel, A. (2014) · Angewandte Chemie International Edition
Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions
Cited by 245
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Exosomes derived from gemcitabine-resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p
Wei, F., Ma, C., Zhou, T., Dong, X., Luo, Q., Geng, L., Ding, L., Zhang, Y., Zhang, L., Li, N., et al. (2017) · Molecular Cancer
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 245
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Major defects in neocortical GABAergic inhibitory circuits in mice lacking the fragile X mental retardation protein
Selby, L., Zhang, C., & Sun, Q.-Q. (2007) · Neuroscience Letters
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 245
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Structure of the Zebrafish Locomotor Repertoire Revealed with Unsupervised Behavioral Clustering
Marques, J. C., Lackner, S., Félix, R., & Orger, M. B. (2018) · Current Biology
Zebrafish Biomedical Research ApplicationsMotor Control and Adaptation
Cited by 245
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Stathmin: A Tubulin-Sequestering Protein Which Forms a Ternary T2S Complex with Two Tubulin Molecules
Jourdain, L., Curmi, P., Sobel, A., Pantaloni, D., & Carlier, M.-F. (1997) · Biochemistry
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 245
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Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing
Lippens, S., Kockx, M., Knaapen, M., Mortier, L., Polakowska, R., Verheyen, A., Garmyn, M., Zwijsen, A., Formstecher, P., Huylebroeck, D., et al. (2000) · Cell Death & Differentiation
Cell death mechanisms and regulationSkin and Cellular Biology Research
Cited by 245
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Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
Rask-Andersen, M., Karlsson, T., Ek, W. E., & Johansson, Å. (2019) · Nature Communications
Genetic Associations and EpidemiologyGenetics and Physical Performance
Cited by 245
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Dorsoventral Axis Formation in the Drosophila Embryo—Shaping and Transducing a Morphogen Gradient
Moussian, B., & Roth, S. (2005) · Current Biology
Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics
Cited by 245
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Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation
Maniaci, C., Hughes, S. J., Testa, A., Chen, W., Lamont, D. J., Rocha, S., Alessi, D. R., Romeo, R., & Ciulli, A. (2017) · Nature Communications
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 245
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Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
Hiller, B., Achleitner, M., Glage, S., Naumann, R., Behrendt, R., & Roers, A. (2012) · Journal of Experimental Medicine
DNA Repair MechanismsRNA regulation and disease
Cited by 245
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Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis
Lv, L., Fang, D., Shi, D., Chen, D., Yan, R., Zhu, Y., Chen, Y., Shao, L., Guo, F., Wu, W., et al. (2016) · Environmental Microbiology
Gut microbiota and healthLiver Diseases and Immunity
Cited by 245
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Connective tissue and fibroblast senescence in skin aging
Wlaschek, M., Maity, P., Makrantonaki, E., & Scharffetter-Kochanek, K. (2021) · Journal of Investigative Dermatology
Telomeres, Telomerase, and SenescenceSkin Protection and Aging
Cited by 245
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Molecular aging and rejuvenation of human muscle stem cells
Carlson, M. E., Suetta, C., Conboy, M. J., Aagaard, P., Mackey, A., Kjaer, M., & Conboy, I. (2009) · EMBO Molecular Medicine
Muscle Physiology and DisordersGenetics, Aging, and Longevity in Model Organisms
Cited by 245
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The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
Deora, V., Lee, J. D., Albornoz, E. A., McAlary, L., Jagaraj, C. J., Robertson, A. A. B., Atkin, J. D., Cooper, M. A., Schroder, K., Yerbury, J. J., et al. (2020) · Glia
Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms
Cited by 245
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Mesenchymal stromal cell apoptosis is required for their therapeutic function
Pang, S. H. M., D’Rozario, J., Mendonca, S., Bhuvan, T., Payne, N. L., Zheng, D., Hisana, A., Wallis, G., Barugahare, A., Powell, D., et al. (2021) · Nature Communications
Mesenchymal stem cell researchCell death mechanisms and regulation
Cited by 245
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Apolipoprotein E exhibits isoform‐specific promotion of lipid efflux from astrocytes and neurons in culture
Michikawa, M., Fan, Q., Isobe, I., & Yanagisawa, K. (2000) · Journal of Neurochemistry
Cholesterol and Lipid MetabolismAlzheimer's disease research and treatments
Cited by 244
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Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression
Vernimmen, D., Gobbi, M. D., Sloane‐Stanley, J. A., Wood, W. G., & Higgs, D. R. (2007) · The EMBO Journal
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 244
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Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL−/− tumors
Zimmer, M., Doucette, D., Siddiqui, N., & Iliopoulos, O. (2004) · Molecular Cancer Research
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 244
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Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway
Davidoff, A. M., Ng, C. Y. C., Zhou, J., Spence, Y., & Nathwani, A. C. (2003) · Blood
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 244
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Prospects for epigenetic epidemiology
Foley, D. L., Craig, J. M., Morley, R., Olsson, C. J., Dwyer, T., Smith, K., & Saffery, R. (2008) · American Journal of Epidemiology
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 244
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DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging
Tiwari, V., & Wilson, D. M. (2019) · The American Journal of Human Genetics
DNA Repair MechanismsGenetic factors in colorectal cancer
Cited by 244
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Targeting the neural extracellular matrix in neurological disorders
Soleman, S., Filippov, M. A., Dityatev, A., & Fawcett, J. W. (2013) · Neuroscience
Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms
Cited by 244
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Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and A β Accumulation
Jazvinšćak Jembrek, M., Hof, P. R., & Šimić, G. (2015) · Oxidative Medicine and Cellular Longevity
Sphingolipid Metabolism and SignalingAlzheimer's disease research and treatments
Cited by 244
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Human Claspin Is Required for Replication Checkpoint Control
Chini, C. C. S., & Chen, J. (2003) · Journal of Biological Chemistry
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 244
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