Check medicine papers: citations, claims and retractions

The cholinergic hypothesis of geriatric memory dysfunction

Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982) · Science

Cholinesterase and Neurodegenerative DiseasesDementia and Cognitive Impairment Research

Cited by 5,545

Cisplatin in cancer therapy: Molecular mechanisms of action

Dasari, S., & Bernard Tchounwou, P. (2014) · European Journal of Pharmacology

Metal complexes synthesis and propertiesCancer therapeutics and mechanisms

Cited by 5,537

Multidrug resistance in cancer: role of ATP–dependent transporters

Gottesman, M. M., Fojo, T., & Bates, S. E. (2002) · Nature Reviews Cancer

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 5,536

Osteoporosis Prevention, Diagnosis, and Therapy

NIH Consensus Development Panel on Osteoporosis Prevention, D. (2001) · JAMA: The Journal of the American Medical Association

Bone health and osteoporosis researchMenopause: Health Impacts and Treatments

Cited by 5,529

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

Maemondo, M., Inoue, A., Kobayashi, K., Sugawara, S., Oizumi, S., Isobe, H., Gemma, A., Harada, M., Yoshizawa, H., Kinoshita, I., et al. (2010) · New England Journal of Medicine

Lung Cancer Treatments and MutationsLung Cancer Diagnosis and Treatment

Cited by 5,525

Adipose Tissue as an Endocrine Organ

Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 5,522

Nivolumab in Previously Untreated Melanoma without BRAF Mutation

Robert, C., Long, G. V., Brady, B., Dutriaux, C., Maio, M., Mortier, L., Hassel, J. C., Rutkowski, P., McNeil, C., Kalinka-Warzocha, E., et al. (2015) · New England Journal of Medicine

Cancer Immunotherapy and BiomarkersCutaneous Melanoma Detection and Management

Cited by 5,519

Natural products as sources of new drugs over the last 25 years

Newman, D. J., & Cragg, G. M. (2007) · Journal of Natural Products

Microbial Natural Products and BiosynthesisMarine Sponges and Natural Products

Cited by 5,517

The Pathogenesis of Rheumatoid Arthritis

McInnes, I. B., & Schett, G. (2011) · New England Journal of Medicine

Rheumatoid Arthritis Research and TherapiesAutoimmune and Inflammatory Disorders Research

Cited by 5,514

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

Beckman, J. S., & Koppenol, W. H. (1996) · American Journal of Physiology-Cell Physiology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 5,513

Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration

Marshall, B., & Warren, J. R. (1984) · The Lancet

Helicobacter pylori-related gastroenterology studiesSalmonella and Campylobacter epidemiology

Cited by 5,509

Osimertinib in Untreated EGFR -Mutated Advanced Non–Small-Cell Lung Cancer

Soria, J.-C., Ohe, Y., Vansteenkiste, J., Reungwetwattana, T., Chewaskulyong, B., Lee, K. H., Dechaphunkul, A., Imamura, F., Nogami, N., Kurata, T., et al. (2018) · New England Journal of Medicine

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 5,508

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesRedox biology and oxidative stress

Cited by 5,508

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

Ridker, P. M., Cushman, M., Stampfer, M. J., Tracy, R. P., & Hennekens, C. H. (1997) · New England Journal of Medicine

Antiplatelet Therapy and Cardiovascular DiseasesLipoproteins and Cardiovascular Health

Cited by 5,504

Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

Kudo, M., Finn, R. S., Qin, S., Han, K.-H., Ikeda, K., Piscaglia, F., Baron, A., Park, J.-W., Han, G., Jassem, J., et al. (2018) · The Lancet

Hepatocellular Carcinoma Treatment and PrognosisColorectal Cancer Treatments and Studies

Cited by 5,497

Diagnosis and classification of diabetes mellitus

American Diabetes Association (2010) · Diabetes Care

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 5,491

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

Rosell, R., Carcereny, E., Gervais, R., Vergnenegre, A., Massuti, B., Felip, E., Palmero, R., Garcia-Gomez, R., Pallares, C., Sanchez, J. M., et al. (2012) · The Lancet Oncology

Lung Cancer Treatments and MutationsLung Cancer Diagnosis and Treatment

Cited by 5,489

Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment

Breivik, H., Collett, B., Ventafridda, V., Cohen, R., & Gallacher, D. (2006) · European Journal of Pain

Musculoskeletal pain and rehabilitationPain Management and Opioid Use

Cited by 5,486

Actual causes of death in the United States

McGinnis, J. M. (1993) · JAMA: The Journal of the American Medical Association

Healthcare Systems and Public HealthCardiovascular Health and Risk Factors

Cited by 5,480

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

Grasselli, G., Zangrillo, A., Zanella, A., Antonelli, M., Cabrini, L., Castelli, A., Cereda, D., Coluccello, A., Foti, G., Fumagalli, R., et al. (2020) · JAMA

COVID-19 Clinical Research StudiesRespiratory Support and Mechanisms

Cited by 5,469

Parkinson's Disease

Dauer, W., & Przedborski, S. (2003) · Neuron

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 5,469

Alzheimer's disease

Scheltens, P., De Strooper, B., Kivipelto, M., Holstege, H., Chételat, G., Teunissen, C. E., Cummings, J., & van der Flier, W. M. (2021) · The Lancet

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 5,465

Oxidative stress and diabetic complications

Giacco, F., & Brownlee, M. (2010) · Circulation Research

Nitric Oxide and Endothelin EffectsAdvanced Glycation End Products research

Cited by 5,461

Mechanisms linking obesity to insulin resistance and type 2 diabetes

Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature

Adipokines, Inflammation, and Metabolic DiseasesPancreatic function and diabetes

Cited by 5,448