Check pharmacology, toxicology and pharmaceutics papers: citations, claims and retractions

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis

Shih, D. M., Wang, Z., Lee, R., Meng, Y., Che, N., Charugundla, S., Qi, H., Wu, J., Pan, C., Brown, J. M., et al. (2015) · Journal of Lipid Research

Pharmacogenetics and Drug MetabolismLipid metabolism and disorders

Cited by 335

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

Michael, S. L., Pumford, N. R., Mayeux, P. R., Niesman, M. R., & Hinson, J. A. (1999) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionImmunotoxicology and immune responses

Cited by 335

Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set

Lenselink, E. B., ten Dijke, N., Bongers, B., Papadatos, G., van Vlijmen, H. W. T., Kowalczyk, W., IJzerman, A. P., & van Westen, G. J. P. (2017) · Journal of Cheminformatics

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 334

Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)

Varma, M. V., Steyn, S. J., Allerton, C., & El-Kattan, A. F. (2015) · Pharmaceutical Research

Computational Drug Discovery MethodsDrug Transport and Resistance Mechanisms

Cited by 334

Methods to Compare Dissolution Profiles and a Rationale for Wide Dissolution Specifications for Metoprolol Tartrate tablets†

Polli, J. E., Rekhi, G. S., Augsburger, L. L., & Shah, V. P. (1997) · Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsAnalytical Methods in Pharmaceuticals

Cited by 334

Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Sante du Quebec, and Endorecherche.

Turgeon, D., Carrier, J.-S., Lévesque, E., Hum, D. W., & Bélanger, A. (2001) · Endocrinology

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 333

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

Ged, C., Rouillon, J., Pichard, L., Combalbert, J., Bressot, N., Bories, P., Michel, H., Beaune, P., & Maurel, P. (1989) · British Journal of Clinical Pharmacology

Pharmacogenetics and Drug MetabolismAdrenal Hormones and Disorders

Cited by 333

The Pine River statement: human health consequences of DDT use

Eskenazi, B., Chevrier, J., Rosas, L. G., Anderson, H. A., Bornman, M. S., Bouwman, H., Chen, A., Cohn, B. A., de Jager, C., Henshel, D. S., et al. (2009) · Environmental Health Perspectives

Pesticide Exposure and ToxicityToxic Organic Pollutants Impact

Cited by 333

Dual or multi-targeting inhibitors: The next generation anticancer agents

Raghavendra, N. M., Pingili, D., Kadasi, S., Mettu, A., & Prasad, S. V. U. M. (2018) · European Journal of Medicinal Chemistry

Computational Drug Discovery MethodsHeterocyclic Compound Synthesis and Bioactivity

Cited by 333

Clinical Pharmacokinetics of Amiodarone

Latini, R., Tognoni, G., & Kates, R. E. (1984) · Clinical Pharmacokinetics

Pharmacogenetics and Drug MetabolismCardiac electrophysiology and arrhythmias

Cited by 333

The Chemical Biology of Naphthoquinones and Its Environmental Implications

Kumagai, Y., Shinkai, Y., Miura, T., & Cho, A. K. (2012) · Annual Review of Pharmacology and Toxicology

Bioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stress

Cited by 332

Effects of petrolatum on stratum corneum structure and function

Ghadially, R., Halkier-Sorensen, L., & Elias, P. M. (1992) · Journal of the American Academy of Dermatology

Advancements in Transdermal Drug DeliveryDermatology and Skin Diseases

Cited by 332

Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure

Marques, P. E., Amaral, S. S., Pires, D. A., Nogueira, L. L., Soriani, F. M., Lima, B. H. F., Lopes, G. A. O., Russo, R. C., Ávila, T. V., Melgaço, J. G., et al. (2012) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 332

Genomic organization of the human catechol O‐methyltransferase gene and its expression from two distinct promoters

TENHUNEN, J., SALMINEN, M., LUNDSTRÖM, K., KIVILUOTO, T., SAVOLAINEN, R., & ULMANEN, I. (1994) · European Journal of Biochemistry

Pharmacogenetics and Drug MetabolismGenomics and Chromatin Dynamics

Cited by 331

PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination

Garinot, M., Fiévez, V., Pourcelle, V., Stoffelbach, F., des Rieux, A., Plapied, L., Theate, I., Freichels, H., Jérôme, C., Marchand-Brynaert, J., et al. (2007) · Journal of Controlled Release

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 331

Empirical scoring functions for structure-based virtual screening: applications, critical aspects, and challenges

Guedes, I. A., Pereira, F. S. S., & Dardenne, L. E. (2018) · Frontiers in Pharmacology

Computational Drug Discovery Methodsvaccines and immunoinformatics approaches

Cited by 331

Suprachoroidal drug delivery to the back of the eye using hollow microneedles

Patel, S. R., Lin, A. S. P., Edelhauser, H. F., & Prausnitz, M. R. (2011) · Pharmaceutical Research

Advanced Drug Delivery SystemsAdvancements in Transdermal Drug Delivery

Cited by 330

A review of network-based approaches to drug repositioning

Lotfi Shahreza, M., Ghadiri, N., Mousavi, S. R., Varshosaz, J., & Green, J. R. (2018) · Briefings in Bioinformatics

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 330

Genetic susceptibility to adverse drug reactions

Pirmohamed, M., & Park, B. K. (2001) · Trends in Pharmacological Sciences

Pharmacogenetics and Drug MetabolismDrug-Induced Adverse Reactions

Cited by 328

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

Rupprecht, R., Rammes, G., Eser, D., Baghai, T. C., Schüle, C., Nothdurfter, C., Troxler, T., Gentsch, C., Kalkman, H. O., Chaperon, F., et al. (2009) · Science

Pharmacological Receptor Mechanisms and EffectsNeuroscience and Neuropharmacology Research

Cited by 328

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

Proctor, W. R., Foster, A. J., Vogt, J., Summers, C., Middleton, B., Pilling, M. A., Shienson, D., Kijanska, M., Ströbel, S., Kelm, J. M., et al. (2017) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 328

Binding MOAD (Mother Of All Databases)

Hu, L., Benson, M. L., Smith, R. D., Lerner, M. G., & Carlson, H. A. (2005) · Proteins: Structure, Function, and Bioinformatics

Computational Drug Discovery MethodsEnzyme Structure and Function

Cited by 328

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Bell, C. C., Dankers, A. C. A., Lauschke, V. M., Sison-Young, R., Jenkins, R., Rowe, C., Goldring, C. E., Park, K., Regan, S. L., Walker, T., et al. (2018) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 327

Chemokine (C‐C motif) receptor 2–positive monocytes aggravate the early phase of acetaminophen‐induced acute liver injury

Mossanen, J. C., Krenkel, O., Ergen, C., Govaere, O., Liepelt, A., Puengel, T., Heymann, F., Kalthoff, S., Lefebvre, E., Eulberg, D., et al. (2016) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 325