Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor
Huang, W., Zhang, J., Washington, M., Liu, J., Parant, J. M., Lozano, G., & Moore, D. D. (2005) · Molecular Endocrinology
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 284
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Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres
MAO, S., XU, J., CAI, C., GERMERSHAUS, O., SCHAPER, A., & KISSEL, T. (2007) · International Journal of Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 283
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Matched Molecular Pairs as a Medicinal Chemistry Tool: Miniperspective
Griffen, E., Leach, A. G., Robb, G. R., & Warner, D. J. (2011) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 282
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The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication
Rask-Andersen, M., Masuram, S., & Schiöth, H. B. (2014) · Annual Review of Pharmacology and Toxicology
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 282
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Gender-related differences in pharmacokinetics and their clinical significance
Tanaka, E. (1999) · Journal of Clinical Pharmacy and Therapeutics
Pharmacogenetics and Drug MetabolismSex and Gender in Healthcare
Cited by 281
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Phytochemistry and biological properties of glabridin
Simmler, C., Pauli, G. F., & Chen, S.-N. (2013) · Fitoterapia
Pharmacological Effects of Natural CompoundsBioactive natural compounds
Cited by 281
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Interactions Between Estrogens and Catechol Amines III. Studies on the Methylation of Catechol Estrogens, Catechol Amines and other Catechols by the Catechol-O-Methyltransferase1 of Human Liver
BALL, P., KNUPPEN, R., HAUPT, M., & BREUER, H. (1972) · The Journal of Clinical Endocrinology & Metabolism
Pharmacogenetics and Drug MetabolismEstrogen and related hormone effects
Cited by 280
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Pharos: collating protein information to shed light on the druggable genome
Nguyen, D.-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., et al. (2017) · Nucleic Acids Research
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 279
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Flip-flop Pharmacokinetics – Delivering a Reversal of Disposition: Challenges and Opportunities During Drug Development
Yáñez, J. A., Remsberg, C. M., Sayre, C. L., Forrest, M. L., & Davies, N. M. (2011) · Therapeutic Delivery
Drug Solubulity and Delivery SystemsPharmaceutical studies and practices
Cited by 279
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Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature: Toxic Effects of Nitrous Oxide Abuse
Garakani, A., Jaffe, R. J., Savla, D., Welch, A. K., Protin, C. A., Bryson, E. O., & McDowell, D. M. (2016) · The American Journal on Addictions
Forensic Toxicology and Drug AnalysisPoisoning and overdose treatments
Cited by 279
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NADPH P450 oxidoreductase: Structure, function, and pathology of diseases
Pandey, A. V., & Flück, C. E. (2013) · Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismMetabolism and Genetic Disorders
Cited by 279
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Entangled Conditional Adversarial Autoencoder for de Novo Drug Discovery
Polykovskiy, D., Zhebrak, A., Vetrov, D., Ivanenkov, Y., Aladinskiy, V., Mamoshina, P., Bozdaganyan, M., Aliper, A., Zhavoronkov, A., & Kadurin, A. (2018) · Molecular Pharmaceutics
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 278
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Molecular Docking Algorithms
Dias, R., & de Azevedo Jr., W. (2008) · Current Drug Targets
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 278
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Poly(Lactic Acid)-Based Microparticles for Drug Delivery Applications: An Overview of Recent Advances
Vlachopoulos, A., Karlioti, G., Balla, E., Daniilidis, V., Kalamas, T., Stefanidou, M., Bikiaris, N. D., Christodoulou, E., Koumentakou, I., Karavas, E., et al. (2022) · Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 277
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Central role of mitochondria in drug-induced liver injury
Pessayre, D., Fromenty, B., Berson, A., Robin, M.-A., Lettéron, P., Moreau, R., & Mansouri, A. (2012) · Drug Metabolism Reviews
Drug-Induced Hepatotoxicity and ProtectionMitochondrial Function and Pathology
Cited by 277
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Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization
Song, B. J., Veech, R. L., Park, S. S., Gelboin, H. V., & Gonzalez, F. J. (1989) · Journal of Biological Chemistry
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 277
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Chemical degradation of peptides and proteins in PLGA: A review of reactions and mechanisms
Houchin, M. L., & Topp, E. M. (2008) · Journal of Pharmaceutical Sciences
Advanced Drug Delivery Systemsbiodegradable polymer synthesis and properties
Cited by 277
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ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
Isoherranen, N., Kunze, K. L., Allen, K. E., Nelson, W. L., & Thummel, K. E. (2004) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 276
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Understanding drug‐likeness
Ursu, O., Rayan, A., Goldblum, A., & Oprea, T. I. (2011) · WIREs Computational Molecular Science
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 276
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Information Decay in Molecular Docking Screens against Holo, Apo, and Modeled Conformations of Enzymes
McGovern, S. L., & Shoichet, B. K. (2003) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 276
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Mol-CycleGAN: a generative model for molecular optimization
Maziarka, Ł., Pocha, A., Kaczmarczyk, J., Rataj, K., Danel, T., & Warchoł, M. (2020) · Journal of Cheminformatics
Computational Drug Discovery MethodsGenerative Adversarial Networks and Image Synthesis
Cited by 275
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Covalent docking of large libraries for the discovery of chemical probes
London, N., Miller, R. M., Krishnan, S., Uchida, K., Irwin, J. J., Eidam, O., Gibold, L., Cimermančič, P., Bonnet, R., Shoichet, B. K., et al. (2014) · Nature Chemical Biology
Computational Drug Discovery MethodsClick Chemistry and Applications
Cited by 274
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Post marketing surveillance of suspected adverse drug reactions through spontaneous reporting: current status, challenges and the future
Alomar, M., Tawfiq, A. M., Hassan, N., & Palaian, S. (2020) · Therapeutic Advances in Drug Safety
Pharmacovigilance and Adverse Drug ReactionsPharmaceutical industry and healthcare
Cited by 272
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Farmers' knowledge, practices and injuries associated with pesticide exposure in rural farming villages in Tanzania
Lekei, E. E., Ngowi, A. V., & London, L. (2014) · BMC Public Health
Pesticide Exposure and ToxicityAgriculture and Farm Safety
Cited by 271
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