Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Pharmacokinetics and Pharmacodynamics in Clinical Use of Scopolamine
Renner, U. D., Oertel, R., & Kirch, W. (2005) · Therapeutic Drug Monitoring
Pharmacogenetics and Drug MetabolismAnesthesia and Sedative Agents
Cited by 314
- Verified
ZINC-22─A Free Multi-Billion-Scale Database of Tangible Compounds for Ligand Discovery
Tingle, B. I., Tang, K. G., Castanon, M., Gutierrez, J. J., Khurelbaatar, M., Dandarchuluun, C., Moroz, Y. S., & Irwin, J. J. (2023) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 314
- Verified
Vascular and Hepatocellular Peroxynitrite Formation during Acetaminophen Toxicity: Role of Mitochondrial Oxidant Stress
Knight, T. R. (2001) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionRedox biology and oxidative stress
Cited by 313
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The future of molecular dynamics simulations in drug discovery
Borhani, D. W., & Shaw, D. E. (2012) · Journal of Computer-Aided Molecular Design
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 313
- Verified
Oxidation of Indole by Cytochrome P450 Enzymes
Gillam, E. M. J., Notley, L. M., Cai, H., De Voss, J. J., & Guengerich, F. P. (2000) · Biochemistry
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 313
- Verified
Utilizing graph machine learning within drug discovery and development
Gaudelet, T., Day, B., Jamasb, A. R., Soman, J., Regep, C., Liu, G., Hayter, J. B. R., Vickers, R., Roberts, C., Tang, J., et al. (2021) · Briefings in Bioinformatics
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 313
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Effects of smoking on the pharmacokinetics of erlotinib
Hamilton, M., Wolf, J. L., Rusk, J., Beard, S. E., Clark, G. M., Witt, K., & Cagnoni, P. J. (2006) · Clinical Cancer Research
Pharmacogenetics and Drug MetabolismLung Cancer Treatments and Mutations
Cited by 312
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Pharmacogenetics of Warfarin Elimination and Its Clinical Implications
Takahashi, H., & Echizen, H. (2001) · Clinical Pharmacokinetics
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 312
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Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission
Kassahun, K., Pearson, P. G., Tang, W., McIntosh, I., Leung, K., Elmore, C., Dean, D., Wang, R., Doss, G., & Baillie, T. A. (2001) · Chemical Research in Toxicology
Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism
Cited by 311
- Verified
Intranasal Treatment of Central Nervous System Dysfunction in Humans
Chapman, C. D., Frey, W. H., Craft, S., Danielyan, L., Hallschmid, M., Schiöth, H. B., & Benedict, C. (2013) · Pharmaceutical Research
Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery
Cited by 310
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Progesterone and Testosterone Hydroxylation by Cytochromes P450 2C19, 2C9, and 3A4 in Human Liver Microsomes
Yamazaki, H., & Shimada, T. (1997) · Archives of Biochemistry and Biophysics
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 310
- Verified
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials
Gayvert, K. M., Madhukar, N. S., & Elemento, O. (2016) · Cell chemical biology
Computational Drug Discovery MethodsPharmacovigilance and Adverse Drug Reactions
Cited by 310
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Predicting Absolute Ligand Binding Free Energies to a Simple Model Site
Mobley, D. L., Graves, A. P., Chodera, J. D., McReynolds, A. C., Shoichet, B. K., & Dill, K. A. (2007) · Journal of Molecular Biology
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 310
- Verified
Pharmacokinetics
Fan, J., & de Lannoy, I. A. M. (2014) · Biochemical Pharmacology
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 309
- Verified
Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry
Andrade, R. J., Lucena, I. M., Kaplowitz, N., García-Muņoz, B., Borraz, Y., Pachkoria, K., García-Cortés, M., Fernández, C. M., Pelaez, G., Rodrigo, L., et al. (2006) · Hepatology
Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions
Cited by 309
- Verified
Biocompatibility and drug delivery systems
Kohane, D. S., & Langer, R. (2010) · Chem. Sci.
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 307
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Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial [ISRCTN45683816]
Akhondzadeh, S., Fallah-Pour, H., Afkham, K., Jamshidi, A.-H., & Khalighi-Cigaroudi, F. (2004) · BMC Complementary and Alternative Medicine
Saffron Plant Research StudiesMedicinal Plant Extracts Effects
Cited by 307
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Surface-Modified Nanocarriers for Nose-To-Brain Delivery: From Bioadhesion to Targeting
Sonvico, F., Clementino, A. R., Buttini, F., Colombo, G., Pescina, S., Stanisçuaski Guterres, S., Raffin Pohlmann, A., & Nicoli, S. (2018) · Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 306
- Verified
Intestinal permeability and its relevance for absorption and elimination
Lennernäs, H. (2007) · Xenobiotica
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 304
- Verified
Estimation of the increase in solubility of drugs as a function of bile salt concentration
Mithani, S. D., Bakatselou, V., TenHoor, C. N., & Dressman, J. B. (1996) · Pharmaceutical Research
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 303
- Verified
How Big Is Too Big for Cell Permeability?
Matsson, P., & Kihlberg, J. (2017) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 303
- Verified
Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes
Lang, D., Yeung, C., Peter, R., Ibarra, C., Gasser, R., Itagaki, K., Philpot, R., & Rettie, A. (1998) · Biochemical Pharmacology
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 303
- Verified
Determination of stratum corneum lipid profile by tape stripping in combination with high-performance thin-layer chromatography
Weerheim, A., & Ponec, M. (2001) · Archives of Dermatological Research
Advancements in Transdermal Drug DeliveryDermatology and Skin Diseases
Cited by 302
- Verified
Effect of smoking on caffeine clearance
Parsons, W. D., & Neims, A. H. (1978) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismCoffee research and impacts
Cited by 302
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