Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport
Jin, Y., Song, Y., Zhu, X., Zhou, D., Chen, C., Zhang, Z., & Huang, Y. (2012) · Biomaterials
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 301
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An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
Ge, Y., Tian, T., Huang, S., Wan, F., Li, J., Li, S., Wang, X., Yang, H., Hong, L., Wu, N., et al. (2021) · Signal Transduction and Targeted Therapy
Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Cited by 300
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Prediction of Human Pharmacokinetics from Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches
Hosea, N. A., Collard, W. T., Cole, S., Maurer, T. S., Fang, R. X., Jones, H., Kakar, S. M., Nakai, Y., Smith, B. J., Webster, R., et al. (2009) · The Journal of Clinical Pharmacology
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 300
- Verified
DDT and human health
BEARD, J. (2006) · Science of The Total Environment
Pesticide Exposure and ToxicityEffects and risks of endocrine disrupting chemicals
Cited by 300
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Machine learning identifies candidates for drug repurposing in Alzheimer’s disease
Rodriguez, S., Hug, C., Todorov, P., Moret, N., Boswell, S. A., Evans, K., Zhou, G., Johnson, N. T., Hyman, B. T., Sorger, P. K., et al. (2021) · Nature Communications
Computational Drug Discovery MethodsAlzheimer's disease research and treatments
Cited by 299
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Engineering biodegradable polyester particles with specific drug targeting and drug release properties
Mohamed, F., & van der Walle, C. F. (2008) · Journal of Pharmaceutical Sciences
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 299
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Crocus sativus L. in the treatment of mild to moderate depression: a double‐blind, randomized and placebo‐controlled trial
Akhondzadeh, S., Tahmacebi‐Pour, N., Noorbala, A., Amini, H., Fallah‐Pour, H., Jamshidi, A., & Khani, M. (2005) · Phytotherapy Research
Saffron Plant Research StudiesMedicinal Plant Extracts Effects
Cited by 298
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Volume of distribution at steady state for a linear pharmacokinetic system with peripheral elimination
Berezhkovskiy, L. M. (2004) · Journal of Pharmaceutical Sciences
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 296
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Deep generative molecular design reshapes drug discovery
Zeng, X., Wang, F., Luo, Y., Kang, S.-G., Tang, J., Lightstone, F. C., Fang, E. F., Cornell, W., Nussinov, R., & Cheng, F. (2022) · Cell Reports Medicine
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 295
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Stochastic Voyages into Uncharted Chemical Space Produce a Representative Library of All Possible Drug-Like Compounds
Virshup, A. M., Contreras-García, J., Wipf, P., Yang, W., & Beratan, D. N. (2013) · Journal of the American Chemical Society
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 294
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A Comparative Study on Chemical Composition and Antioxidant Activity of Ginger ( Zingiber officinale ) and Cumin ( Cuminum cyminum )
El-Ghorab, A. H., Nauman, M., Anjum, F. M., Hussain, S., & Nadeem, M. (2010) · Journal of Agricultural and Food Chemistry
Ginger and Zingiberaceae researchEssential Oils and Antimicrobial Activity
Cited by 294
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In silico design of novel probes for the atypical opioid receptor MRGPRX2
Lansu, K., Karpiak, J., Liu, J., Huang, X.-P., McCorvy, J. D., Kroeze, W. K., Che, T., Nagase, H., Carroll, F. I., Jin, J., et al. (2017) · Nature Chemical Biology
Computational Drug Discovery MethodsReceptor Mechanisms and Signaling
Cited by 293
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Machine Learning for Drug-Target Interaction Prediction
Chen, R., Liu, X., Jin, S., Lin, J., & Liu, J. (2018) · Molecules
Computational Drug Discovery MethodsMachine Learning in Bioinformatics
Cited by 292
- Verified
Developmental cholinotoxicants: nicotine and chlorpyrifos
Slotkin, T. A. (1999) · Environmental Health Perspectives
Pesticide Exposure and ToxicityNicotinic Acetylcholine Receptors Study
Cited by 292
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SHORT COMMUNICATION: Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans
Bell, D. A., Taylor, J. A., Butler, M. A., Stephens, E. A., Wiest, J., Brubaker, L. H., Kadlubar, F. F., & Lucier, G. W. (1993) · Carcinogenesis
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 292
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A Force Field with Discrete Displaceable Waters and Desolvation Entropy for Hydrated Ligand Docking
Forli, S., & Olson, A. J. (2012) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 290
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Optimization of curcumin nanoemulsion for intranasal delivery using design of experiment and its toxicity assessment
Sood, S., Jain, K., & Gowthamarajan, K. (2014) · Colloids and Surfaces B: Biointerfaces
Advanced Drug Delivery SystemsAdvancements in Transdermal Drug Delivery
Cited by 289
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Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
Dambach, D. M., Watson, L. M., Gray, K. R., Durham, S. K., & Laskin, D. L. (2002) · Hepatology
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 289
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Quantitative Structure−Activity Relationship Modeling of Rat Acute Toxicity by Oral Exposure
Zhu, H., Martin, T. M., Ye, L., Sedykh, A., Young, D. M., & Tropsha, A. (2009) · Chemical Research in Toxicology
Computational Drug Discovery MethodsAnimal testing and alternatives
Cited by 287
- VerifiedRetracted
WITHDRAWN—a resource for withdrawn and discontinued drugs
Siramshetty, V. B., Nickel, J., Omieczynski, C., Gohlke, B.-O., Drwal, M. N., & Preissner, R. (2016) · Nucleic Acids Research
Pharmacovigilance and Adverse Drug ReactionsComputational Drug Discovery Methods
Cited by 286
- Verified
Drug repurposing: far beyond new targets for old drugs
Oprea, T. I., & Mestres, J. (2012) · The AAPS Journal
Computational Drug Discovery MethodsPharmaceutical Economics and Policy
Cited by 285
- Verified
Benchmarking AlphaFold‐enabled molecular docking predictions for antibiotic discovery
Wong, F., Krishnan, A., Zheng, E. J., Stärk, H., Manson, A. L., Earl, A. M., Jaakkola, T., & Collins, J. J. (2022) · Molecular Systems Biology
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 284
- Verified
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome
Dolphin, C. T., Janmohamed, A., Smith, R. L., Shephard, E. A., & Phillips, L. R. (1997) · Nature Genetics
Pharmacogenetics and Drug MetabolismMetabolism and Genetic Disorders
Cited by 284
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Measurement of Serum Acetaminophen–Protein Adducts in Patients With Acute Liver Failure
Davern, T. J., James, L. P., Hinson, J. A., Polson, J., Larson, A. M., Fontana, R. J., Lalani, E., Munoz, S., Shakil, A. O., & Lee, W. M. (2006) · Gastroenterology
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 284
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