Check pharmacology, toxicology and pharmaceutics papers: citations, claims and retractions

Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT “pie”

Riches, Z., Stanley, E. L., Bloomer, J. C., & Coughtrie, M. W. H. (2009) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismGlutathione Transferases and Polymorphisms

Cited by 365

Performance of machine-learning scoring functions in structure-based virtual screening.

Wójcikowski, M., Ballester, P. J., & Siedlecki, P. (2017) · Scientific Reports

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 364

Bioavailability study of berberine and the enhancing effects of TPGS on intestinal absorption in rats

Chen, W., Miao, Y.-Q., Fan, D.-J., Yang, S.-S., Lin, X., Meng, L.-K., & Tang, X. (2011) · AAPS PharmSciTech

Drug Solubulity and Delivery SystemsBerberine and alkaloids research

Cited by 363

Organotypic liver culture models: meeting current challenges in toxicity testing

LeCluyse, E. L., Witek, R. P., Andersen, M. E., & Powers, M. J. (2012) · Critical Reviews in Toxicology

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 363

The National Cancer Institute ALMANAC: a comprehensive screening resource for the detection of anticancer drug pairs with enhanced therapeutic activity

Holbeck, S. L., Camalier, R., Crowell, J. A., Govindharajulu, J. P., Hollingshead, M., Anderson, L. W., Polley, E., Rubinstein, L., Srivastava, A., Wilsker, D., et al. (2017) · Cancer Research

Computational Drug Discovery MethodsCancer Cells and Metastasis

Cited by 359

Insights into Direct Nose to Brain Delivery: Current Status and Future Perspective

Mittal, D., Ali, A., Md, S., Baboota, S., Sahni, J. K., & Ali, J. (2014) · Drug Delivery

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 359

Mechanism of Action of N-Acetylcysteine in the Protection Against the Hepatotoxicity of Acetaminophen in Rats In Vivo

Lauterburg, B. H., Corcoran, G. B., & Mitchell, J. R. (1983) · Journal of Clinical Investigation

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 358

Therapeutic applications of implantable drug delivery systems

Dash, A., & Cudworth, G. (1998) · Journal of Pharmacological and Toxicological Methods

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 358

A Systematic Cheminformatics Analysis of Functional Groups Occurring in Natural Products

Ertl, P., & Schuhmann, T. (2019) · Journal of Natural Products

Computational Drug Discovery MethodsMicrobial Natural Products and Biosynthesis

Cited by 358

Target identification among known drugs by deep learning from heterogeneous networks

Zeng, X., Zhu, S., Lu, W., Liu, Z., Huang, J., Zhou, Y., Fang, J., Huang, Y., Guo, H., Li, L., et al. (2020) · Chemical Science

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 357

Machine‐learning scoring functions to improve structure‐based binding affinity prediction and virtual screening

Ain, Q. U., Aleksandrova, A., Roessler, F. D., & Ballester, P. J. (2015) · WIREs Computational Molecular Science

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 357

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

Bourganis, V., Kammona, O., Alexopoulos, A., & Kiparissides, C. (2018) · European Journal of Pharmaceutics and Biopharmaceutics

Advanced Drug Delivery SystemsBarrier Structure and Function Studies

Cited by 357

The biopharmaceutical aspects of nasal mucoadhesive drug delivery

Ugwoke, M. I., Verbeke, N., & Kinget, R. (2001) · Journal of Pharmacy and Pharmacology

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 355

Therapeutic applications of hydrogels in oral drug delivery

Sharpe, L. A., Daily, A. M., Horava, S. D., & Peppas, N. A. (2014) · Expert Opinion on Drug Delivery

Advanced Drug Delivery SystemsHydrogels: synthesis, properties, applications

Cited by 354

Deep learning in drug discovery: opportunities, challenges and future prospects

Lavecchia, A. (2019) · Drug Discovery Today

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 353

Quantitative analysis of the olfactory pathway for drug delivery to the brain

Thorne, R. G., Emory, C. R., Ala, T. A., & Frey, W. H. (1995) · Brain Research

Advanced Drug Delivery SystemsOlfactory and Sensory Function Studies

Cited by 352

Alternatives to Biological Skin in Permeation Studies: Current Trends and Possibilities

Neupane, R., Boddu, S. H. S., Renukuntla, J., Babu, R. J., & Tiwari, A. K. (2020) · Pharmaceutics

Advancements in Transdermal Drug DeliveryAdvanced Drug Delivery Systems

Cited by 351

Pesticide exposure in children

Roberts, J. R., Karr, C. J., COUNCIL ON ENVIRONMENTAL HEALTH, Paulson, J. A., Brock-Utne, A. C., Brumberg, H. L., Campbell, C. C., Lanphear, B. P., Osterhoudt, K. C., Sandel, M. T., et al. (2012) · Pediatrics

Pesticide Exposure and ToxicityAgricultural safety and regulations

Cited by 351

Acetaminophen Overdose: 662 Cases With Evaluation of Oral Acetylcysteine Treatment

Rumack, B. H. (1981) · Archives of Internal Medicine

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 350

The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology

Kadurin, A., Aliper, A., Kazennov, A., Mamoshina, P., Vanhaelen, Q., Khrabrov, K., & Zhavoronkov, A. (2017) · Oncotarget

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 350

The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice

Yamamoto, Y., Moore, R., Goldsworthy, T. L., Negishi, M., & Maronpot, R. R. (2004) · Cancer Research

Pharmacogenetics and Drug MetabolismCarcinogens and Genotoxicity Assessment

Cited by 350

General approach for the calculation of tissue to plasma partition coefficients

Schmitt, W. (2008) · Toxicology in Vitro

Computational Drug Discovery MethodsProtein Interaction Studies and Fluorescence Analysis

Cited by 349

Drug repositioning: a machine-learning approach through data integration

Napolitano, F., Zhao, Y., Moreira, V. M., Tagliaferri, R., Kere, J., D’Amato, M., & Greco, D. (2013) · Journal of Cheminformatics

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 349

Acetaminophen Hepatotoxicity and Acute Liver Failure

Chun, L. J., Tong, M. J., Busuttil, R. W., & Hiatt, J. R. (2009) · Journal of Clinical Gastroenterology

Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments

Cited by 348