Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Hepatotoxicity of commonly used drugs: nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs
Chitturi, S., & George, J. (2002) · Seminars in Liver Disease
Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions
Cited by 216
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Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review
Teka, T., Zhang, L., Ge, X., Li, Y., Han, L., & Yan, X. (2022) · Phytochemistry
Bioactive natural compoundsPhytochemistry and Biological Activities
Cited by 216
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Target selection in drug discovery
Knowles, J., & Gromo, G. (2003) · Nature Reviews Drug Discovery
Computational Drug Discovery MethodsScience, Research, and Medicine
Cited by 216
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Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease
Chidiac, A. S., Buckley, N. A., Noghrehchi, F., & Cairns, R. (2023) · Expert Opinion on Drug Metabolism & Toxicology
Drug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments
Cited by 215
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Bayer’s in silico ADMET platform: a journey of machine learning over the past two decades
Göller, A. H., Kuhnke, L., Montanari, F., Bonin, A., Schneckener, S., ter Laak, A., Wichard, J., Lobell, M., & Hillisch, A. (2020) · Drug Discovery Today
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 215
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A genome-wide positioning systems network algorithm for in silico drug repurposing
Cheng, F., Lu, W., Liu, C., Fang, J., Hou, Y., Handy, D. E., Wang, R., Zhao, Y., Yang, Y., Huang, J., et al. (2019) · Nature Communications
Computational Drug Discovery MethodsBioinformatics and Genomic Networks
Cited by 215
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Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump
Aleo, M. D., Luo, Y., Swiss, R., Bonin, P. D., Potter, D. M., & Will, Y. (2014) · Hepatology
Drug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance Mechanisms
Cited by 215
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In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
Thomas, N., Holm, R., Müllertz, A., & Rades, T. (2012) · Journal of Controlled Release
Drug Solubulity and Delivery SystemsAdvancements in Transdermal Drug Delivery
Cited by 215
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Design and development of ligand-appended polysaccharidic nanoparticles for the delivery of oxaliplatin in colorectal cancer
Jain, A., Jain, S. K., Ganesh, N., Barve, J., & Beg, A. M. (2010) · Nanomedicine: Nanotechnology, Biology and Medicine
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 214
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Pesticide toxicity and the developing brain
Eskenazi, B., Rosas, L. G., Marks, A. R., Bradman, A., Harley, K., Holland, N., Johnson, C., Fenster, L., & Barr, D. B. (2008) · Basic & Clinical Pharmacology & Toxicology
Pesticide Exposure and ToxicityEffects and risks of endocrine disrupting chemicals
Cited by 214
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Liver-specific Deletion of the NADPH-Cytochrome P450 Reductase Gene
Gu, J., Weng, Y., Zhang, Q.-Y., Cui, H., Behr, M., Wu, L., Yang, W., Zhang, L., & Ding, X. (2003) · Journal of Biological Chemistry
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
Cited by 214
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Chemotherapeutic Drugs Released from Polymers: Distribution of 1,3-bis(2-chloroethyl)-l-nitrosourea in the Rat Brain
Fung, L. K., Shin, M., Tyler, B., Brem, H., & Saltzman, W. M. (1996) · Pharmaceutical Research
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 213
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Mechanisms of Carbon Tetrachloride Hepatotoxicity
Clawson, G. A. (2008) · Pathology and Immunopathology Research
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 213
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Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance
Kidambi, S., Yarmush, R. S., Novik, E., Chao, P., Yarmush, M. L., & Nahmias, Y. (2009) · Proceedings of the National Academy of Sciences
Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism
Cited by 213
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Experimental pathology of local tissue damage induced by Bothrops asper snake venom
Gutiérrez, J. M., Rucavado, A., Chaves, F., Díaz, C., & Escalante, T. (2009) · Toxicon
Venomous Animal Envenomation and StudiesAmphibian and Reptile Biology
Cited by 213
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Acetaminophen/paracetamol: A history of errors, failures and false decisions
Brune, K., Renner, B., & Tiegs, G. (2015) · European Journal of Pain
Drug-Induced Hepatotoxicity and ProtectionHistorical Medical Research and Treatments
Cited by 213
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Untargeted Metabolomic Profiling as an Evaluative Tool of Fenofibrate-Induced Toxicology in Fischer 344 Male Rats
Ohta, T., Masutomi, N., Tsutsui, N., Sakairi, T., Mitchell, M., Milburn, M. V., Ryals, J. A., Beebe, K. D., & Guo, L. (2009) · Toxicologic Pathology
Drug-Induced Hepatotoxicity and ProtectionMetabolomics and Mass Spectrometry Studies
Cited by 213
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eToxPred: a machine learning-based approach to estimate the toxicity of drug candidates
Pu, L., Naderi, M., Liu, T., Wu, H.-C., Mukhopadhyay, S., & Brylinski, M. (2019) · BMC Pharmacology and Toxicology
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 212
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Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis
Achour, B., Barber, J., & Rostami-Hodjegan, A. (2014) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 212
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Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting
Mahajan, H. S., Mahajan, M. S., Nerkar, P. P., & Agrawal, A. (2014) · Drug Delivery
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 212
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Computer-assisted drug design
Hopfinger, A. J. (1985) · Journal of Medicinal Chemistry
Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds
Cited by 212
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FREQUENCY OF TRUE ADVERSE REACTIONS TO MEASLES-MUMPS-RUBELLA VACCINE
Peltola, H., & Heinonen, O. (1986) · The Lancet
Pharmacovigilance and Adverse Drug ReactionsVirology and Viral Diseases
Cited by 212
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An assessment of the limits of detection, sensitivity and specificity of three devices for public health-based drug checking of fentanyl in street-acquired samples
Green, T. C., Park, J. N., Gilbert, M., McKenzie, M., Struth, E., Lucas, R., Clarke, W., & Sherman, S. G. (2020) · International Journal of Drug Policy
Forensic Toxicology and Drug AnalysisOpioid Use Disorder Treatment
Cited by 211
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Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
Kleinstreuer, N. C., Yang, J., Berg, E. L., Knudsen, T. B., Richard, A. M., Martin, M. T., Reif, D. M., Judson, R. S., Polokoff, M., Dix, D. J., et al. (2014) · Nature Biotechnology
Computational Drug Discovery MethodsAnimal testing and alternatives
Cited by 211
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