Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Conducting and interpreting disproportionality analyses derived from spontaneous reporting systems
Cutroneo, P. M., Sartori, D., Tuccori, M., Crisafulli, S., Battini, V., Carnovale, C., Rafaniello, C., Capuano, A., Poluzzi, E., Moretti, U., et al. (2024) · Frontiers in Drug Safety and Regulation
Pharmacovigilance and Adverse Drug ReactionsStatistical Methods in Clinical Trials
Cited by 224
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The solubility–permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone
Dahan, A., Miller, J. M., Hoffman, A., Amidon, G. E., & Amidon, G. L. (2010) · Journal of Pharmaceutical Sciences
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 224
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Prediction of in vivo drug clearance from in vitro data. I: Impact of inter-individual variability
Howgate, E. M., Rowland Yeo, K., Proctor, N. J., Tucker, G. T., & Rostami-Hodjegan, A. (2006) · Xenobiotica
Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices
Cited by 223
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Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I)
Morelli, X., Bourgeas, R., & Roche, P. (2011) · Current Opinion in Chemical Biology
Computational Drug Discovery MethodsChemical Synthesis and Analysis
Cited by 223
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High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo
Antoine, D. J., Williams, D. P., Kipar, A., Jenkins, R. E., Regan, S. L., Sathish, J. G., Kitteringham, N. R., & Park, B. K. (2009) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionCell death mechanisms and regulation
Cited by 223
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Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis
Kakisaka, K., Cazanave, S. C., Fingas, C. D., Guicciardi, M. E., Bronk, S. F., Werneburg, N. W., Mott, J. L., & Gores, G. J. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology
Drug-Induced Hepatotoxicity and ProtectionLiver Disease Diagnosis and Treatment
Cited by 222
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Assessment of Binding Affinity via Alchemical Free-Energy Calculations
Kuhn, M., Firth-Clark, S., Tosco, P., Mey, A. S. J. S., Mackey, M., & Michel, J. (2020) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsAdvanced Chemical Physics Studies
Cited by 222
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Simultaneous presence of DDT and pyrethroid residues in human breast milk from a malaria endemic area in South Africa
Bouwman, H., Sereda, B., & Meinhardt, H. M. (2006) · Environmental Pollution
Pesticide Exposure and ToxicityPesticide Residue Analysis and Safety
Cited by 222
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Everted gut sac model as a tool in pharmaceutical research: limitations and applications
Alam, M. A., Al-Jenoobi, F. I., & Al-mohizea, A. M. (2012) · Journal of Pharmacy and Pharmacology
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 221
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Ginger in gastrointestinal disorders: A systematic review of clinical trials
Nikkhah Bodagh, M., Maleki, I., & Hekmatdoost, A. (2019) · Food Science & Nutrition
Ginger and Zingiberaceae researchGarlic and Onion Studies
Cited by 221
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From Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New Chemistry
Haynes, R. K., & Vonwiller, S. C. (1997) · Accounts of Chemical Research
Phytochemical compounds biological activitiesMalaria Research and Control
Cited by 220
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Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase
Falany, C. N., Krasnykh, V., & Falany, J. L. (1995) · The Journal of Steroid Biochemistry and Molecular Biology
Pharmacogenetics and Drug MetabolismEstrogen and related hormone effects
Cited by 220
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Drug Similarity Integration Through Attentive Multi-view Graph Auto-Encoders
Ma, T., Xiao, C., Zhou, J., & Wang, F. (2018) · Proceedings of the Twenty-Seventh International Joint Conference on Artificial Intelligence
Computational Drug Discovery MethodsAdvanced Graph Neural Networks
Cited by 220
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Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study
Li, X., Ostropolets, A., Makadia, R., Shoaibi, A., Rao, G., Sena, A. G., Martinez-Hernandez, E., Delmestri, A., Verhamme, K., Rijnbeek, P. R., et al. (2021) · BMJ
Pharmacovigilance and Adverse Drug ReactionsSARS-CoV-2 and COVID-19 Research
Cited by 219
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Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors
Proctor, N. J., Tucker, G. T., & Rostami-Hodjegan, A. (2004) · Xenobiotica
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 219
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Drug design by machine learning: the use of inductive logic programming to model the structure-activity relationships of trimethoprim analogues binding to dihydrofolate reductase.
King, R. D., Muggleton, S., Lewis, R. A., & Sternberg, M. J. (1992) · Proceedings of the National Academy of Sciences
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 219
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Antioxidant Activity and Hepatoprotective Effects of Whey Protein and Spirulina in Rats
Gad, A. S., Khadrawy, Y. A., El-Nekeety, A. A., Mohamed, S. R., Hassan, N. S., & Abdel-Wahhab, M. A. (2011) · Nutrition
Drug-Induced Hepatotoxicity and ProtectionAntioxidant Activity and Oxidative Stress
Cited by 218
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Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure: A Systematic Review and Meta-analysis
Milosavljevic, F., Bukvic, N., Pavlovic, Z., Miljevic, C., Pešic, V., Molden, E., Ingelman-Sundberg, M., Leucht, S., & Jukic, M. M. (2021) · JAMA Psychiatry
Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology
Cited by 218
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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice
Hinson, J. A., Pike, S. L., Pumford, N. R., & Mayeux, P. R. (1998) · Chemical Research in Toxicology
Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology
Cited by 218
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Controversies over human health and ecological impacts of glyphosate: Is it to be banned in modern agriculture?
Meftaul, I. M., Venkateswarlu, K., Dharmarajan, R., Annamalai, P., Asaduzzaman, M., Parven, A., & Megharaj, M. (2020) · Environmental Pollution
Pesticide Exposure and ToxicityPesticide and Herbicide Environmental Studies
Cited by 218
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CYP2A6 genotype and the metabolism and disposition kinetics of nicotine
BENOWITZ, N., SWAN, G., JACOBIII, P., LESSOVSCHLAGGAR, C., & TYNDALE, R. (2006) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismSmoking Behavior and Cessation
Cited by 217
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Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers
Modaghegh, M.-H., Shahabian, M., Esmaeili, H.-A., Rajbai, O., & Hosseinzadeh, H. (2008) · Phytomedicine
Saffron Plant Research StudiesComplementary and Alternative Medicine Studies
Cited by 217
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PH sensitive N-succinyl chitosan grafted polyacrylamide hydrogel for oral insulin delivery
Mukhopadhyay, P., Sarkar, K., Bhattacharya, S., Bhattacharyya, A., Mishra, R., & Kundu, P. P. (2014) · Carbohydrate Polymers
Advanced Drug Delivery SystemsHydrogels: synthesis, properties, applications
Cited by 217
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Drug-Metabolizing Ability of Molybdenum Hydroxylases
Kitamura, S., Sugihara, K., & Ohta, S. (2006) · Drug Metabolism and Pharmacokinetics
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 216
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