Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Intranasal administration of interferon beta bypasses the blood–brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis
Ross, T. M., Martinez, P. M., Renner, J. C., Thorne, R. G., Hanson, L. R., & Frey, W. H. (2004) · Journal of Neuroimmunology
Advanced Drug Delivery SystemsMultiple Sclerosis Research Studies
Cited by 242
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Human hepatocytes as a tool for studying toxicity and drug metabolism
Gomez-Lechon, M., Donato, M., Castell, J., & Jover, R. (2003) · Current Drug Metabolism
Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism
Cited by 242
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SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System
Fadini, G. P., Bonora, B. M., & Avogaro, A. (2017) · Diabetologia
Pharmacovigilance and Adverse Drug ReactionsDiabetes Treatment and Management
Cited by 242
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The interindividual differences in the 3‐demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors
Rasmussen (2002) · Pharmacogenetics
Pharmacogenetics and Drug MetabolismCoffee research and impacts
Cited by 241
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PEGylated Protein Drugs: Basic Science and Clinical Applications
Veronese, F. M. (2009) · Birkhäuser Basel eBooks
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 241
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Consensus scoring criteria for improving enrichment in virtual screening.
Yang, J.-M., Chen, Y.-F., Shen, T.-W., Kristal, B. S., & Hsu, D. F. (2005) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds
Cited by 241
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Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates
Lauschke, V. M., Hendriks, D. F. G., Bell, C. C., Andersson, T. B., & Ingelman-Sundberg, M. (2016) · Chemical Research in Toxicology
Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research
Cited by 241
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PAMPA—critical factors for better predictions of absorption
Avdeef, A., Bendels, S., Di, L. I., Faller, B., Kansy, M., Sugano, K., & Yamauchi, Y. (2007) · Journal of Pharmaceutical Sciences
Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms
Cited by 240
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In silico toxicology protocols
Myatt, G. J., Ahlberg, E., Akahori, Y., Allen, D., Amberg, A., Anger, L. T., Aptula, A., Auerbach, S., Beilke, L., Bellion, P., et al. (2018) · Regulatory Toxicology and Pharmacology
Computational Drug Discovery MethodsAnimal testing and alternatives
Cited by 240
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Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
Rassu, G., Soddu, E., Posadino, A. M., Pintus, G., Sarmento, B., Giunchedi, P., & Gavini, E. (2017) · Colloids and Surfaces B: Biointerfaces
Advanced Drug Delivery SystemsRNA Interference and Gene Delivery
Cited by 239
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Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?
Isoherranen, N., & Thummel, K. E. (2013) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismPregnancy and Medication Impact
Cited by 239
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Assessing the association of pioglitazone use and bladder cancer through drug adverse event reporting
Piccinni, C., Motola, D., Marchesini, G., & Poluzzi, E. (2011) · Diabetes Care
Pharmacovigilance and Adverse Drug ReactionsMetabolism, Diabetes, and Cancer
Cited by 239
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Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
Neuvonen, P. J., & Jalava, K.-M. (1996) · Clinical Pharmacology & Therapeutics
Pharmacogenetics and Drug MetabolismLipoproteins and Cardiovascular Health
Cited by 238
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Demystifying Multitask Deep Neural Networks for Quantitative Structure–Activity Relationships
Xu, Y., Ma, J., Liaw, A., Sheridan, R. P., & Svetnik, V. (2017) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 238
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Characterization and evaluation of chitosan nanoparticles for dopamine brain delivery
Trapani, A., De Giglio, E., Cafagna, D., Denora, N., Agrimi, G., Cassano, T., Gaetani, S., Cuomo, V., & Trapani, G. (2011) · International Journal of Pharmaceutics
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 238
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Pharmacogenetics: Implications of race and ethnicity on defining genetic profiles for personalized medicine
Ortega, V. E., & Meyers, D. A. (2014) · Journal of Allergy and Clinical Immunology
Pharmacogenetics and Drug MetabolismRace, Genetics, and Society
Cited by 237
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Let’s not forget tautomers.
Martin, Y. C. (2009) · Journal of Computer-Aided Molecular Design
Computational Drug Discovery MethodsAdvanced Chemical Physics Studies
Cited by 237
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A model binding site for testing scoring functions in molecular docking.
Wei, B. Q., Baase, W. A., Weaver, L. H., Matthews, B. W., & Shoichet, B. K. (2002) · Journal of Molecular Biology
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 237
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Artificial Intelligence for Drug Discovery: Are We There Yet?
Hasselgren, C., & Oprea, T. I. (2024) · Annual Review of Pharmacology and Toxicology
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 236
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Lectin-mediated mucosal delivery of drugs and microparticles
Clark, M. A., Hirst, B. H., & Jepson, M. A. (2000) · Advanced Drug Delivery Reviews
Advanced Drug Delivery SystemsGlycosylation and Glycoproteins Research
Cited by 236
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Interpretation of Quantitative Structure-Activity Relationship Models: Past, Present, and Future
Polishchuk, P. (2017) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsExplainable Artificial Intelligence (XAI)
Cited by 236
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Tongkat Ali (Eurycoma longifolia Jack): A review on its ethnobotany and pharmacological importance
Bhat, R., & Karim, A. A. (2010) · Fitoterapia
Phytochemical compounds biological activitiesPhytochemicals and Medicinal Plants
Cited by 236
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A Systematic Review of Pesticide Exposure, Associated Risks, and Long-Term Human Health Impacts
Shekhar, C., Khosya, R., Thakur, K., Mahajan, D., Kumar, R., Kumar, S., & Sharma, A. K. (2024) · Toxicology Reports
Pesticide Exposure and ToxicityAgricultural safety and regulations
Cited by 236
- Verified
3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies
Gunness, P., Mueller, D., Shevchenko, V., Heinzle, E., Ingelman-Sundberg, M., & Noor, F. (2013) · Toxicological Sciences
Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives
Cited by 236
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