Most cited pharmacology, toxicology and pharmaceutics papers
- Verified
Effectiveness of molecular fingerprints for exploring the chemical space of natural products
Boldini, D., Ballabio, D., Consonni, V., Todeschini, R., Grisoni, F., & Sieber, S. A. (2024) · Journal of Cheminformatics
Computational Drug Discovery MethodsMachine Learning in Materials Science
Cited by 97
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A Comparison of Pharmacokinetics between Humans and Monkeys
Akabane, T., Tabata, K., Kadono, K., Sakuda, S., Terashita, S., & Teramura, T. (2010) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismAnimal testing and alternatives
Cited by 97
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A policy model to evaluate the benefits, risks and costs of warfarin pharmacogenomic testing
Meckley, L. M., Gudgeon, J. M., Anderson, J. L., Williams, M. S., & Veenstra, D. L. (2010) · PharmacoEconomics
Pharmacogenetics and Drug MetabolismHealth Systems, Economic Evaluations, Quality of Life
Cited by 97
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Cytochrome P450 inhibition using recombinant proteins and mass spectrometry/multiple reaction monitoring technology in a cassette incubation
Weaver, R., Graham, K. S., Beattie, I. G., & Riley, R. J. (2003) · Drug Metabolism and Disposition
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms
Cited by 97
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Systematic exploitation of multiple receptor conformations for virtual ligand screening.
Bottegoni, G., Rocchia, W., Rueda, M., Abagyan, R., & Cavalli, A. (2011) · PLoS ONE
Computational Drug Discovery MethodsReceptor Mechanisms and Signaling
Cited by 96
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Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles
Chiappetta, D. A., Facorro, G., Rubin de Celis, E., & Sosnik, A. (2011) · Nanomedicine Nanotechnology Biology and Medicine
Drug Solubulity and Delivery SystemsSurfactants and Colloidal Systems
Cited by 96
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Coloring Molecules with Explainable Artificial Intelligence for Preclinical Relevance Assessment
Jiménez-Luna, J., Skalic, M., Weskamp, N., & Schneider, G. (2021) · Journal of Chemical Information and Modeling
Computational Drug Discovery MethodsExplainable Artificial Intelligence (XAI)
Cited by 96
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Intranasal delivery of paroxetine nanoemulsion via the olfactory region for the management of depression: Formulation, behavioural and biochemical estimation
Pandey, Y. R., Kumar, S., Gupta, B. K., Ali, J., & Baboota, S. (2016) · Nanotechnology
Advanced Drug Delivery SystemsAdvancements in Transdermal Drug Delivery
Cited by 96
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Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle
Bartelink, I. H., Jones, E. F., Shahidi‐Latham, S. K., Lee, P. R. E., Zheng, Y., Vicini, P., van ‘t Veer, L., Wolf, D., Iagaru, A., Kroetz, D. L., et al. (2019) · Clinical Pharmacology & Therapeutics
Computational Drug Discovery MethodsDrug Transport and Resistance Mechanisms
Cited by 96
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Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: A pilot study
Mansour, M. S., Ni, Y.-M., Roberts, A. L., Kelleman, M., RoyChoudhury, A., & St-Onge, M.-P. (2012) · Metabolism
Ginger and Zingiberaceae researchRegulation of Appetite and Obesity
Cited by 96
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AlphaFold, allosteric, and orthosteric drug discovery: Ways forward
Nussinov, R., Zhang, M., Liu, Y., & Jang, H. (2023) · Drug Discovery Today
Computational Drug Discovery MethodsProtein Structure and Dynamics
Cited by 96
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Methylation of the DPYD Promoter: An Alternative Mechanism for Dihydropyrimidine Dehydrogenase Deficiency in Cancer Patients
Ezzeldin, H. H., Lee, A. M., Mattison, L. K., & Diasio, R. B. (2005) · Clinical Cancer Research
Pharmacogenetics and Drug MetabolismEpigenetics and DNA Methylation
Cited by 96
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BCS Biowaivers: Similarities and Differences Among EMA, FDA, and WHO Requirements
Davit, B. M., Kanfer, I., Tsang, Y. C., & Cardot, J.-M. (2016) · The AAPS Journal
Drug Solubulity and Delivery SystemsPharmaceutical studies and practices
Cited by 96
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Pharmacokinetics of the green tea derivative, EGCG, by the topical route of administration in mouse and human skin
Dvorakova, K., Dorr, R. T., Valcic, S., Timmermann, B., & Alberts, D. S. (1999) · Cancer Chemotherapy and Pharmacology
Advancements in Transdermal Drug DeliveryTea Polyphenols and Effects
Cited by 96
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Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs
Cunha-Reis, C., Machado, A., Barreiros, L., Araújo, F., Nunes, R., Seabra, V., Ferreira, D., Segundo, M. A., Sarmento, B., & das Neves, J. (2016) · Journal of Controlled Release
Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery
Cited by 95
- Verified
Clinically Significant Drug Interactions with Atypical Antipsychotics
Kennedy, W. K., Jann, M. W., & Kutscher, E. C. (2013) · CNS Drugs
Pharmacogenetics and Drug MetabolismSchizophrenia research and treatment
Cited by 95
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Involvement of cytochrome P450 in cisplatin treatment: implications for toxicity
Quintanilha, J. C. F., de Sousa, V. M., Visacri, M. B., Amaral, L. S., Santos, R. M. M., Zambrano, T., Salazar, L. A., & Moriel, P. (2017) · Cancer Chemotherapy and Pharmacology
Chemotherapy-induced organ toxicity mitigationPharmacogenetics and Drug Metabolism
Cited by 95
- Verified
Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7.
Yamano, S., Aoyama, T., McBride, O. W., Hardwick, J. P., Gelboin, H. V., & Gonzalez, F. J. (1989) · Molecular Pharmacology
Pharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 95
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Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level
Sugiyama, T., & Sadzuka, Y. (2004) · Cancer Letters
Chemotherapy-induced organ toxicity mitigationChemotherapy-induced cardiotoxicity and mitigation
Cited by 95
- Verified
Biological mechanism profiling using an annotated compound library
Root, D. E., Flaherty, S. P., Kelley, B. P., & Stockwell, B. R. (2003) · Chemistry & Biology
Computational Drug Discovery MethodsHeterocyclic Compound Synthesis and Bioactivity
Cited by 95
- Verified
Long-acting delivery systems for narcotic antagonists. 1
Woodland, J. H. R., Yolles, S., Blake, D. A., Helrich, M., & Meyer, F. J. (1973) · Journal of Medicinal Chemistry
Advanced Drug Delivery SystemsPain Management and Opioid Use
Cited by 95
- Verified
Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data
Chen, X., Shen, F., Gonzaludo, N., Malhotra, A., Rogert, C., Taft, R. J., Bentley, D. R., & Eberle, M. A. (2021) · The Pharmacogenomics Journal
Pharmacogenetics and Drug MetabolismGenomics and Rare Diseases
Cited by 95
- Verified
N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats
Nardai, S., László, M., Szabó, A., Alpár, A., Hanics, J., Zahola, P., Merkely, B., Frecska, E., & Nagy, Z. (2020) · Experimental Neurology
Pharmacological Receptor Mechanisms and EffectsNeuroprotection in Cerebral Ischemia
Cited by 94
- Verified
Acetaminophen Nephrotoxicity in CD-1 Mice
Hart, S. G. E., Beierschmitt, W. P., Wyand, D. S., Khairallah, E. A., & Cohen, S. D. (1994) · Toxicology and Applied Pharmacology
Drug-Induced Hepatotoxicity and ProtectionAcute Kidney Injury Research
Cited by 94
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