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Cited by 630Nutritional Studies and DietFood composition and propertiesCardiovascular Health and Risk Factors

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Dietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies

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Pereira, Mark A., O'Reilly, Eilis, Augustsson, Katarina, Fraser, Gary E., Goldbourt, Uri, Heitmann, Berit L., Hallmans, Goran, Knekt, Paul, Liu, Simin, Pietinen, Pirjo, Spiegelman, Donna, Stevens, June, Virtamo, Jarmo, Willett, Walter C., Ascherio, Alberto·2004·Archives of Internal Medicine
DOI 10.1001/archinte.164.4.370
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Abstract

BACKGROUND: Few epidemiologic studies of dietary fiber intake and risk of coronary heart disease have compared fiber types (cereal, fruit, and vegetable) or included sex-specific results. The purpose of this study was to conduct a pooled analysis of dietary fiber and its subtypes and risk of coronary heart disease. METHODS: We analyzed the original data from 10 prospective cohort studies from the United States and Europe to estimate the association between dietary fiber intake and the risk of coronary heart disease. RESULTS: Over 6 to 10 years of follow-up, 5249 incident total coronary cases and 2011 coronary deaths occurred among 91058 men and 245186 women. After adjustment for demographics, body mass index, and lifestyle factors, each 10-g/d increment of energy-adjusted and measurement error-corrected total dietary fiber was associated with a 14% (relative risk [RR], 0.86; 95% confidence interval [CI], 0.78-0.96) decrease in risk of all coronary events and a 27% (RR, 0.73; 95% CI, 0.61-0.87) decrease in risk of coronary death. For cereal, fruit, and vegetable fiber intake (not error corrected), RRs corresponding to 10-g/d increments were 0.90 (95% CI, 0.77-1.07), 0.84 (95% CI, 0.70-0.99), and 1.00 (95% CI, 0.88-1.13), respectively, for all coronary events and 0.75 (95% CI, 0.63-0.91), 0.70 (95% CI, 0.55-0.89), and 1.00 (95% CI, 0.82-1.23), respectively, for deaths. Results were similar for men and women. CONCLUSION: Consumption of dietary fiber from cereals and fruits is inversely associated with risk of coronary heart disease.

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Metadata

Authors
Pereira, M. A., O'Reilly, E., Augustsson, K., Fraser, G. E., Goldbourt, U., Heitmann, B. L., Hallmans, G., Knekt, P., Liu, S., Pietinen, P., Spiegelman, D., Stevens, J., Virtamo, J., Willett, W. C., & Ascherio, A.
Affiliations
  • University of Minnesota (US)
  • Loma Linda University (US)
  • Sheba Medical Center (IL)
  • University of Copenhagen (DK)
  • Finnish Institute for Health and Welfare (FI)
  • Harvard University (US)
Corresponding author
Pereira, Mark A.
ORCID
Venue
Archives of Internal Medicine
Publisher
American Medical Association (AMA)
Published
2004-02-23
Volume
164
Issue
4
Pages
370
ISSN
0003-9926 (ISSN-L)
DOI
10.1001/archinte.164.4.370
OpenAlex
W2126541538
Cited by
630
References
41
Citations by year
2026: 2 · 2025: 10 · 2024: 4 · 2023: 22 · 2022: 13 · 2021: 17 · 2020: 21 · 2019: 20 · 2018: 26 · 2017: 20 · 2016: 27 · 2015: 40 · 2014: 48 · 2013: 44 · 2012: 55
FWCI
35.47
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Archives of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders
National Heart, Lung, and Blood Institute (R01 HL58904, R01HL058904)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
dietary fiber, coronary artery disease, cereal fiber, fruit fiber, plant fibers, coronary heart disease mortality, sex differences, pooled analysis of cohort studies, measurement error correction
MeSH terms
Edible Grain, Coronary Artery Disease, Dietary Fiber, Female, Fruit, Humans, Male, Nutritional Physiological Phenomena, Cohort Studies, Risk Assessment

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