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Mild Cognitive Impairment Can Be Distinguished From Alzheimer Disease and Normal Aging for Clinical Trials
Abstract
BACKGROUND: Mild cognitive impairment (MCI) represents a transitional state between the cognitive changes of normal aging and very early dementia and is becoming increasingly recognized as a risk factor for Alzheimer disease (AD). The Memory Impairment Study (MIS) is a multicenter clinical trial in patients with MCI designed to evaluate whether vitamin E or donepezil is effective at delaying the time to a clinical diagnosis of AD. OBJECTIVE: To describe the baseline characteristics of patients with MCI recruited for the MIS and compare them with those of elderly controls and patients with AD in another clinical trial. DESIGN: Descriptive and comparative study of patients with MCI participating in a multicenter clinical trial. SETTING: Memory disorder centers in the United States and Canada. PATIENTS: A total of 769 patients with MCI, 107 cognitively normal elderly controls, 122 patients with very mild AD (Clinical Dementia Rating [CDR] 0.5), and 183 patients with mild AD (CDR 1.0) were evaluated. Patients in the MIS met operational criteria for amnestic MCI. Controls were recruited in parallel with the MCI group, underwent the same assessments, and had a CDR of 0. MAIN OUTCOME MEASURES: Clinical, neuropsychologic, functional, neuroimaging, and genetic measures. RESULTS: Mean +/- SD Alzheimer's Disease Assessment Scale-Cognitive Subscale scores were 5.6 +/- 3.3 for controls, 11.3 +/- 4.4 for patients with MCI, 18.0 +/- 6.2 for the AD CDR 0.5 group, and 25.2 +/- 8.8 for the AD CDR 1.0 group. Compared with controls, patients with MCI were most impaired on memory tasks, with less severe impairments in other cognitive domains. Patients with MCI were more likely than controls but less likely than patients with AD to carry the apolipoprotein E epsilon4 allele. Patients with MCI had hippocampal volumes that were intermediate between those of controls and patients with AD. CONCLUSIONS: Patients with MCI had a predominant memory impairment with relative sparing of other cognitive domains and were intermediate between clinically normal individuals and patients with AD on cognitive and functional ratings. These results demonstrate the successful implementation of operational criteria for this unique group of at-risk patients in a multicenter clinical trial.
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“MCI could be considered a prodromal phase, representing a transitional condition between healthy aging and very mild AD [28].”
From Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation (2022) · cites this paper as [28]
Citations
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Mild Cognitive Impairment: Clinical Characterization and Outcome
Petersen, R. C., Smith, G. E., Waring, S. C., Ivnik, R. J., Tangalos, E. G., & Kokmen, E. (1999) · Archives of Neurology · doi:10.1001/archneur.56.3.303 · Cited by 8,980
The Global Deterioration Scale for assessment of primary degenerative dementia
Reisberg, ., Ferris, S. H., de Leon, M. J., & Crook, T. H. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.9.1136 · Cited by 5,122
Manual for the Wechsler Adult Intelligence Scale.
Wechsler, D. (1955) · Psychological Corp. eBooks · Cited by 4,941
Current concepts in mild cognitive impairment
Petersen, R. C., Doody, R., Kurz, A., Mohs, R. C., Morris, J. C., Rabins, P. V., Ritchie, K., Rossor, M., Thal, L., & Winblad, B. (2001) · Archives of Neurology · doi:10.1001/archneur.58.12.1985 · Cited by 4,781
Kaplan, E., Goodglass, H., Weıntraub, S., & Segal, O. (2001) · Medical Entomology and Zoology · Cited by 4,378
Petersen, R. C., Stevens, J. C., Ganguli, M., Tangalos, E. G., Cummings, J. L., & DeKosky, S. T. (2001) · Neurology · doi:10.1212/wnl.56.9.1133 · Cited by 2,065
Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease
Morris, J. C., Storandt, M., Miller, J. P., McKeel, D. W., Price, J. L., Rubin, E. H., & Berg, L. (2001) · Archives of Neurology · doi:10.1001/archneur.58.3.397 · Cited by 1,871
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Items 101–200 of 963
Mild cognitive impairment: an epidemiological perspective
Ritchie, K. A. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.4/kritchie · Cited by 167
Are Empirically-Derived Subtypes of Mild Cognitive Impairment Consistent with Conventional Subtypes?
Clark, L. R., Delano-Wood, L., Libon, D. J., McDonald, C. R., Nation, D. A., Bangen, K. J., Jak, A. J., Au, R., Salmon, D. P., & Bondi, M. W. (2013) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617713000313 · Cited by 167
Clinical Prediction of Alzheimer Disease Dementia Across the Spectrum of Mild Cognitive Impairment
Dickerson, B. C., Sperling, R. A., Hyman, B. T., Albert, M., & Blacker, D. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.12.1443 · Cited by 172
Lu, Y., Tan, L., & Wang, X. (2019) · Neuroscience Bulletin · doi:10.1007/s12264-019-00361-0 · Cited by 168
Stomrud, E., Hansson, O., Blennow, K., Minthon, L., & Londos, E. (2007) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000105017 · Cited by 170
Naming of objects, faces and buildings in mild cognitive impairment
Ahmed, S., Arnold, R. J., Thompson, S., Graham, K. S., & Hodges, J. R. (2007) · Cortex · doi:10.1016/j.cortex.2007.02.002 · Cited by 175
Trajectory of mild cognitive impairment onset
Howieson, D. B., Carlson, N. E., Moore, M. M., Wasserman, D. K., ABENDROTH, C. D., Payne-Murphy, J. C., & Kaye, J. A. (2008) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617708080375 · Cited by 167
Tong, T., Gao, Q., Guerrero, R., Ledig, C., Chen, L., Rueckert, D., & Initiative, A. D. N. (2016) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2016.2549363 · Cited by 167
Rozzini, L., Chilovi, B. V., Conti, M. Z., Bertoletti, E., Delrio, I., Trabucchi, M., & Padovani, A. (2007) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1816 · Cited by 160
Adlam, A., Patterson, K. E., Bozeat, S., & Hodges, J. R. (2010) · Neurocase · doi:10.1080/13554790903405693 · Cited by 159
Progression of Alzheimer's disease as measured by Clinical Dementia Rating Sum of Boxes scores
Williams, M., Storandt, M., Roe, C. M., & Morris, J. C. (2012) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2012.01.005 · Cited by 160
Mild Cognitive Impairment Is Early-Stage Alzheimer Disease
Morris, J. C. (2006) · Archives of Neurology · doi:10.1001/archneur.63.1.15 · Cited by 157
Neuroimaging biomarkers for clinical trials of disease-modifying therapies in Alzheimer’s disease
Dickerson, B. C., & Sperling, R. A. (2005) · Neurotherapeutics · doi:10.1602/neurorx.2.2.348 · Cited by 159
Borroni, B., Anchisi, D., Paghera, B., Vicini, B., Kerrouche, N., Garibotto, V., Terzi, A., Vignolo, L. A., Luca, M. D., Giubbini, R., et al. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.12.010 · Cited by 156
Artificial Intelligence for Alzheimer’s Disease: Promise or Challenge?
Fabrizio, C., Termine, A., Caltagirone, C., & Sancesario, G. M. (2021) · Diagnostics · doi:10.3390/diagnostics11081473 · Cited by 163
Clinical trials in mild cognitive impairment: lessons for the future
Jelić, V. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.072926 · Cited by 156
Zhang, Y., Zhang, H., Chen, X., Lee, S., & Shen, D. G. (2017) · Scientific Reports · doi:10.1038/s41598-017-06509-0 · Cited by 154
Reddy, P. H. (2006) · BioMed Research International · doi:10.1155/jbb/2006/31372 · Cited by 154
Computer aided Alzheimer's disease diagnosis by an unsupervised deep learning technology
Bi, X., Li, S., Xiao, B., Li, Y., Wang, G., & Ma, X. (2019) · Neurocomputing · doi:10.1016/j.neucom.2018.11.111 · Cited by 152
Ries, M. L., Carlsson, C. M., Rowley, H. A., Sager, M. A., Gleason, C. E., Asthana, S., & Johnson, S. C. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01684.x · Cited by 151
Performance-Based Measures of Everyday Function in Mild Cognitive Impairment
Goldberg, T. E., Koppel, J. L., Keehlisen, L., Christen, E., Dreses‐Werringloer, U., Conejero‐Goldberg, C., Gordon, M. L., & Davies, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09050692 · Cited by 155
Reddy, P. H. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.06.012 · Cited by 147
Shiino, A., Watanabe, T., Maeda, K., Kotani, E., Akiguchi, I., & Matsuda, M. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.06.010 · Cited by 150
Ahmadlou, M., Adeli, A., Bajo, R., & Adeli, H. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2013.08.033 · Cited by 146
Eyler, L. T., Elman, J. A., Hatton, S. N., Gough, S., Mischel, A. K., Hagler, D. J., Franz, C. E., Docherty, A. R., Fennema‐Notestine, C., Gillespie, N. A., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-180847 · Cited by 152
Multiple Cognitive Deficits in Amnestic Mild Cognitive Impairment
Kramer, J. H., Nelson, A., Johnson, J. K., Yaffe, K. S., Glenn, S., Rosen, H. J., & Miller, B. L. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000095303 · Cited by 144
Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI
Jack, C. R., Petersen, R. C., Grundman, M., Jin, S., Gamst, A. C., Ward, C. P., Sencakova, D., Doody, R. S., & Thal, L. J. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.03.004 · Cited by 144
Self-citationNeuropsychological testing and assessment for dementia
Jacova, C., Kertesz, A., Blair, M., Fisk, J. D., & Feldman, H. (2007) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2007.07.011 · Cited by 154
Pereira, J. B., Mijalkov, M., Kakaei, E., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Spenger, C., Lovestone, S., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw128 · Cited by 142
Diagnostic utility of hippocampal size and mean diffusivity in amnestic MCI.
Müller, M. J., Greverus, D., Weibrich, C., Dellani, P. R., Scheurich, A., Stoeter, P., & Fellgiebel, A. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.01.009 · Cited by 140
Impact of social relationships on Alzheimer’s memory impairment: mechanistic studies
Hsiao, Y., Chang, C., & Gean, P. W. (2018) · Journal of Biomedical Science · doi:10.1186/s12929-018-0404-x · Cited by 152
Learning Decreases Aβ*56 and Tau Pathology and Ameliorates Behavioral Decline in 3xTg-AD Mice
Billings, L. M., Green, K. N., McGaugh, J. L., & LaFerla, F. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4800-06.2007 · Cited by 145
Ito, K., Corrigan, B., Zhao, Q., French, J. L., Miller, R., Soares, H. D., Katz, E., Nicholas, T., Billing, B., Anziano, R., et al. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.03.018 · Cited by 140
Zhuang, L., Sachdev, P. S., Trollor, J. N., Reppermund, S., Kochan, N. A., Brodaty, H., & Wen, W. X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058887 · Cited by 142
Reed, T. T., Pierce Jr., W. M., Turner, D. M., Markesbery, W. R., & Allan Butterfield, D. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00478.x · Cited by 135
López, N., Tormo, C., Blas, I. D., Llinares, I., & Alom, J. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-121528 · Cited by 135
Vitamin E for Alzheimer's disease and mild cognitive impairment
Isaac, M. G. E. K. N., Quinn, R., & Tabet, N. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002854.pub2 · Cited by 133
Plasma Cortisol and Progression of Dementia in Subjects With Alzheimer-Type Dementia
Csernansky, J. G., Dong, H., Fagan, A. M., Wang, L., Xiong, C., Holtzman, D. M., & Morris, J. C. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.12.2164 · Cited by 426
López‐Sanz, D., Bruña, R., Garcés, P., Martín-Buro, M. C., Walter, S., Delgado‐Losada, M. L., Montenegro, M., López-Higes, R., Marcos, A., & Maestú, F. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00109 · Cited by 129
Alzheimer's Disease A Century Later
Caselli, R. J., Beach, T. G., Yaari, R., & Reiman, E. M. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n1118 · Cited by 129
Grothe, M. J., Heinsen, H., Amaro, E., Grinberg, L. T., & Teipel, S. J. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv062 · Cited by 130
??-Secretase Inhibitors for Alzheimer??s Disease
Barten, D. M., Meredith, J. E., Zaczek, R. C., Houston, J. G., & Albright, C. F. (2006) · Drugs in R&D · doi:10.2165/00126839-200607020-00003 · Cited by 129
Microglia-derived extracellular vesicles in Alzheimer’s Disease: A double-edged sword
Trotta, T., Antonietta Panaro, M., Cianciulli, A., Mori, G., Di Benedetto, A., & Porro, C. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.12.020 · Cited by 126
Neurobiological Highlights of Cognitive Impairment in Psychiatric Disorders
Morozova, A. Y., Zorkina, Y., Abramova, O. V., Pavlova, O., Ka, P., Soloveva, K., Volkova, M., Alekseeva, P. A., Andryshchenko, A., Kostyuk, G. P., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031217 · Cited by 132
Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease?
Visser, P. J. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.047720 · Cited by 126
Sharifi-Rad, J., Rapposelli, S., Sestito, S., Herrera-Bravo, J., Arancibia-Diaz, A., Salazar, L. A., Yeskaliyeva, B., Beyatli, A., Leyva-Gómez, G., González-Contreras, C., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12091515 · Cited by 125
“MCI could be considered a prodromal phase, representing a transitional condition between healthy aging and very mild AD [28].”
BackgroundResting-State Multi-Spectrum Functional Connectivity Networks for Identification of MCI Patients
Chong-yaw Wee, A., Yap, P., Denny, K., Browndyke, J. N., Potter, G. G., Welsh-Bohmer, K. A., Wang, L., & Shen, D. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037828 · Cited by 125
Hodges, J. R., Erzinçlioğlu, S., & Patterson, K. E. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000092534 · Cited by 125
Fisher, G. G., Franks, M. M., Plassman, B. L., Brown, S. L., Potter, G. G., Llewellyn, D., Rogers, M. A. M., & Langa, K. M. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03304.x · Cited by 123
Yang, H., Xu, H. J., Li, Q., Jin, Y., Jiang, W., Wang, J., Wu, Y., Li, W., Yang, C., Li, X., et al. (2019) · General Psychiatry · doi:10.1136/gpsych-2018-100005 · Cited by 123
Bajo, R., Maestú, F., Nevado, Á., Sancho, M., Gutiérrez, R., Campo, P., Castellanos, N. P., Gil, P., Moratti, S., Pereda, E., et al. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100177 · Cited by 129
Blasko, I., Jellinger, K. A., Kemmler, G., Krampla, W. W., Jungwirth, S., Wichart, I., Tragl, K. H., & Fischer, P. A. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.09.002 · Cited by 121
n-3 LCPUFA improves cognition: The young, the old and the sick
Joffre, C., Nadjar, A., Lebbadi, M., Calon, F., & Layé, S. (2014) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2014.05.001 · Cited by 130
Mild Cognitive Impairment in Older Adults
Geda, Y. E. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0291-x · Cited by 124
Feng, Y., Bai, L., Ren, Y., Chen, S., Wang, H., Zhang, W., & Tian, J. (2012) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2012.01.003 · Cited by 117
Schinka, J. A., Loewenstein, D., Raj, A., Schoenberg, M. R., Banko, J. L., Potter, H., & Duara, R. (2010) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181e56d5a · Cited by 117
Therapeutic application of melatonin in mild cognitive impairment.
Cardinali, D. P., Vigo, D. E., Olivar, N., Vidal, M. F., Furio, A. M., & Brusco, L. I. (2012) · Europe PMC (PubMed Central) · Cited by 116
Kiuchi, K., Morikawa, M., Taoka, T., Nagashima, T., Yamauchi, T., Makinodan, M., Norimoto, K., Hashimoto, K., Kosaka, J., Inoue, Y., et al. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.052 · Cited by 118
Johns, E. K., Phillips, N. A., Belleville, S., Goupil, D., Babins, L., Kelner, N., Ska, B., Gilbert, B., Massoud, F., de Boysson, C., et al. (2012) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617712000069 · Cited by 133
Morimoto, B. H., Schmechel, D., Hirman, J., Blackwell, A., Keith, J., Gold, M., & on behalf of the AL-108-211 Study Investigators (2013) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000348347 · Cited by 115
A Novel Framework for Classification of Different Alzheimer’s Disease Stages Using CNN Model
dar, G. M. U. D., Bhagat, A., Ansarullah, S. I., Othman, M. T. B., Hamid, Y., Alkahtani, H. K., Ullah, I., & Hamam, H. (2023) · Electronics · doi:10.3390/electronics12020469 · Cited by 115
Mild cognitive impairment and cognitive impairment, no dementia: Part A, concept and diagnosis
Chertkow, H. M., Nasreddine, Z. S., Joanette, Y., Drolet, V., Kirk, J., Massoud, F., Belleville, S., & Bergman, H. (2007) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2007.07.013 · Cited by 117
Brain-wide slowing of spontaneous alpha rhythms in mild cognitive impairment
Garcés, P., Vicente, R., Wibral, M., Pineda‐Pardo, J. A., López, M. E., Aurtenetxe, S., Marcos, A., de Andrés, M. E., Yus, M., Sancho, M., et al. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00100 · Cited by 113
Pedrosa, H., De, A., Guerreiro, M., Marôco, J. P., Simões, M. R., Galasko, D. R., & de Mendonça, A. (2010) · The journal of nutrition health & aging · doi:10.1007/s12603-010-0102-1 · Cited by 115
Hadley, E. C., Lakatta, E. G., Morrison‐Bogorad, M., Warner, H. R., & Hodes, R. J. (2005) · Cell · doi:10.1016/j.cell.2005.01.030 · Cited by 111
for the members of the Alzheimer’s Disease Cooperative Study Group*, van Straaten, E. C. W., Harvey, D., Scheltens, P., Barkhof, F., Petersen, R. C., Thal, L. J., Jack, C. R., & DeCarli, C. S. (2008) · Journal of Neurology · doi:10.1007/s00415-008-0874-y · Cited by 112
Serum high sensitivity C-reactive protein and cognitive function in elderly women
Komulainen, P., Lakka, T. A., Kivipelto, M., Hassinen, M., Penttila, I. M., Helkala, E.-L., Gylling, H. K., Nissinen, A. M., & Rauramaa, R. (2007) · Age and Ageing · doi:10.1093/ageing/afm051 · Cited by 115
Mitchell, J., Arnold, R. J., Dawson, K., Nestor, P. J., & Hodges, J. R. (2009) · Journal of Neurology · doi:10.1007/s00415-009-5152-0 · Cited by 109
CSF Aβ42, Tau and phosphorylated Tau, APOE ɛ4 allele and MCI type in progressive MCI
Herukka, S., Helisalmi, S., Hallikainen, M., Tervo, S., Soininen, H. S., & Pirttilä, T. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.02.001 · Cited by 113
Dementia and mild cognitive impairment in adults with intellectual disability: Issues of diagnosis
Krinsky‐McHale, S. J., & Silverman, W. P. (2013) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.1126 · Cited by 116
Imaging Correlates of Memory and Concussion History in Retired National Football League Athletes
Strain, J. F., Womack, K. B., Didehbani, N., Spence, J. S., Conover, H., Hart, J., Kraut, M. A., & Cullum, C. M. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2015.0206 · Cited by 117
Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment
Xie, B., Zhou, H., Zhang, R., Song, M., Yu, L., Wang, L., Liu, Z., Zhang, Q., Cui, D., Wang, X., et al. (2015) · Journal of Alzheimer's Disease · doi:10.3233/jad-142847 · Cited by 97
Conversion of MCI to dementia: Role of proton magnetic resonance spectroscopy
Metastasio, A., Rinaldi, P., Tarducci, R., Mariani, E., Feliziani, F. T., Cherubini, A., Pelliccioli, G. P., Gobbi, G., Senin, U., & Mecocci, P. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.05.002 · Cited by 107
Verbal learning and memory deficits in Mild Cognitive Impairment
Ribeiro, F., Guerreiro, M., & de Mendonça, A. (2006) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390600629775 · Cited by 117
Meditation for Adults with Mild Cognitive Impairment: A Pilot Randomized Trial
Wells, R. E., Kerr, C. E., Wolkin, J., Dossett, M., Davis, R. B., Walsh, J., Wall, R. B., Kong, J., Kaptchuk, T., Press, D., et al. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12179 · Cited by 106
The functional anatomy of divided attention in amnestic mild cognitive impairment
Dannhauser, T. M., Walker, Z., Stevens, T., Lee, L., Seal, M., & Shergill, S. S. (2005) · Brain · doi:10.1093/brain/awh413 · Cited by 106
Frith, E., Shivappa, N., Mann, J. R., Hébert, J. R., Wirth, M. D., & Loprinzi, P. D. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114517003804 · Cited by 105
A critical review of chronic traumatic encephalopathy
Iverson, G. L., Gardner, A. J., McCrory, P., Zafonte, R., & Castellani, R. J. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.008 · Cited by 103
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment
Orgeta, V., Leung, P., del-Pino-Casado, R., Qazi, A., Orrell, M., Spector, A. E., & Methley, A. M. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009125.pub3 · Cited by 103
López‐Sanz, D., Bruña, R., Garcés, P., Cámara, C., Serrano, N., Rodríguez‐Rojo, I. C., Delgado‐Losada, M. L., Montenegro, M. V. R., López-Higes, R., Yus, M., et al. (2016) · Scientific Reports · doi:10.1038/srep37685 · Cited by 106
Jicha, G. A., & Carr, S. A. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1237 · Cited by 107
Towards a multifactorial approach for prediction of bipolar disorder in at risk populations
Brietzke, E. M., Mansur, R. B., Soczynska, J. K., Kapczinski, F. P., Bressan, R. A., & McIntyre, R. S. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.02.016 · Cited by 103
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Metadata
- Authors
- Grundman, M.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Grundman, Michael
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2004-01-01
- Volume
- 61
- Issue
- 1
- Pages
- 59
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W2112436745
- Cited by
- 972
- References
- 34
- Citations by year
- 2026: 15 · 2025: 19 · 2024: 34 · 2023: 34 · 2022: 37 · 2021: 60 · 2020: 52 · 2019: 49 · 2018: 44 · 2017: 52 · 2016: 37 · 2015: 42 · 2014: 51 · 2013: 62 · 2012: 47
- FWCI
- 32.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (AG 010483, U19AG010483)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Keywords
- mild cognitive impairment, Alzheimer's disease, normal aging, amnestic MCI, memory impairment, APOE ε4, hippocampal volume, Clinical Dementia Rating, vitamin E, donepezil, dementia risk, inclusion and exclusion criteria
- MeSH terms
- Aged, Aging, Alzheimer Disease, Brain, Clinical Trials as Topic, Cognition Disorders, Female, Humans, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Risk Factors
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