Increasing Cardiovascular Disease Burden Due to Diabetes Mellitus: The Framingham Heart Study

Fox, Caroline S.; Coady, Sean; Sorlie, Paul D.; D’Agostino, Ralph B.; Pencina, Michael J.; Vasan, Ramachandran S.; Meigs, James B.; Levy, Daniel; Savage, Peter J.

doi:10.1161/circulationaha.106.658948

Cited by 656Diabetes, Cardiovascular Risks, and LipoproteinsHealthcare Systems and Public HealthCardiovascular Health and Risk Factors

Increasing Cardiovascular Disease Burden Due to Diabetes Mellitus: The Framingham Heart Study

Fox, Caroline S., Coady, Sean, Sorlie, Paul D., D’Agostino, Ralph B., Pencina, Michael J., Vasan, Ramachandran S., Meigs, James B., Levy, Daniel +1 more·2007·Circulation

DOI 10.1161/circulationaha.106.658948

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Abstract

Background— Marked reductions in cardiovascular disease (CVD) morbidity and mortality have occurred in the United States over the last 50 years. We tested the hypothesis that the relative burden of CVD attributable to diabetes mellitus (DM) has increased over the past 5 decades. Methods and Results— Participants aged 45 to 64 years from the Framingham Heart Study, who attended examinations in an “early” time period (1952 to 1974), were compared with those who attended examinations in a later time period (1975 to 1998). The risk of CVD events (n=133 among those with and 1093 among those without DM) attributable to DM in the 2 time periods was assessed with Cox proportional hazards models; population attributable risk of DM as a CVD risk factor was calculated for each time period. The age- and sex-adjusted hazard ratio for DM as a CVD risk factor was 3.0 (95% CI, 2.3 to 3.9) in the earlier time period and 2.5 (95% CI, 1.9 to 3.2) in the later time period. The population attributable risk for DM as a CVD risk factor increased from 5.4% (95% CI, 3.8% to 6.9%) in the earlier time period to 8.7% (95% CI, 5.9% to 11.4%) in the later time period ( P for attributable risk ratio=0.04), although multivariable adjustment resulted in attenuation of these findings ( P =0.12); most of these observations were found among men. Conclusions— The proportion of CVD attributable to DM has increased over the past 50 years in Framingham. These findings emphasize the need for increased efforts to prevent DM and to aggressively treat and control CVD risk factors among those with DM.

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Diabetes-related morbidity and mortality is primarily due to cardiovascular complications.
“diabetes-related morbidity and mortality is primarily due to cardiovascular complications [17,18,19].”
From Recent Experimental Studies of Maternal Obesity, Diabetes during Pregnancy and the Developmental Origins of Cardiovascular Disease (2022) · cites this paper as [19]

Incidence, Predictors, and Outcome of Thrombosis After Successful Implantation of Drug-Eluting Stents
Iakovou, I. P. (2005) · JAMA · doi:10.1001/jama.293.17.2126 · Cited by 3,136 · see citing works
Overweight and obesity in the United States: prevalence and trends, 1960–1994
Flegal, K., Carroll, M., Kuczmarski, R., & Johnson, C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800541 · Cited by 3,045 · see citing works
The Continuing Epidemics of Obesity and Diabetes in the United States
Mokdad, A. H. (2001) · JAMA · doi:10.1001/jama.286.10.1195 · Cited by 2,730 · see citing works
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703 · see citing works
Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991
Kuczmarski, R. J. (1994) · JAMA · doi:10.1001/jama.272.3.205 · Cited by 2,362 · see citing works
Cholesterol Lowering With Simvastatin Improves Prognosis of Diabetic Patients With Coronary Heart Disease: A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)
Pyörälä, K., Pedersen, T. R., Kjekshus, J., Faergeman, O., Olsson, A. G., Thorgeirsson, G., & The Scandinavian Simvastatin Survival Study (4S) Group (1997) · Diabetes Care · doi:10.2337/diacare.20.4.614 · Cited by 1,623 · see citing works
Increasing Prevalence of Overweight Among US Adults
Kuczmarski, R. J. (1994) · JAMA · doi:10.1001/jama.1994.03520030047027 · Cited by 1,574 · see citing works
Comparison of coronary bypass surgery with angioplasty in patients with multivessel disease.
Bourassa, M., Frye, R., King, S., Detre, K., Alderman, E., Andrews, K., & Sopko, G. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607253350401 · Cited by 1,489 · see citing works
Poor Control of Risk Factors for Vascular Disease Among Adults With Previously Diagnosed Diabetes
Saydah, S. H. (2004) · JAMA · doi:10.1001/jama.291.3.335 · Cited by 1,357 · see citing works
Diabetes trends in the U.S.: 1990-1998.
Mokdad, A. H., Ford, E. S., Bowman, B. A., Nelson, D. E., Engelgau, M. M., Vinicor, F., & Marks, J. S. (2000) · Diabetes Care · doi:10.2337/diacare.23.9.1278 · Cited by 1,042 · see citing works
Cardiovascular Events and Their Reduction With Pravastatin in Diabetic and Glucose-Intolerant Myocardial Infarction Survivors With Average Cholesterol Levels: Subgroup Analyses in the Cholesterol And Recurrent Events (CARE) Trial
Goldberg, R. B., Mellies, M. J., Sacks, F. M., Moyé, L. A., Howard, B. V., Howard, W. J., Davis, B. R., Cole, T. G., Pfeffer, M. A., & Braunwald, E. (1998) · Circulation · doi:10.1161/01.cir.98.23.2513 · Cited by 986 · see citing works
Secular Trends in Cardiovascular Disease Risk Factors According to Body Mass Index in US Adults
Gregg, E. W. (2005) · JAMA · doi:10.1001/jama.293.15.1868 · Cited by 959 · see citing works
Effect of Diuretic-Based Antihypertensive Treatment on Cardiovascular Disease Risk in Older Diabetic Patients With Isolated Systolic Hypertension
Curb, J. D. (1996) · JAMA · doi:10.1001/jama.1996.03540230036032 · Cited by 955 · see citing works
Appointment of New Associate Editor for Circulation
Willerson, J. (1996) · Circulation · doi:10.1161/01.cir.94.6.1193 · Cited by 918 · see citing works
Diabetes and Decline in Heart Disease Mortality in US Adults
Gu, K. (1999) · JAMA · doi:10.1001/jama.281.14.1291 · Cited by 856 · see citing works
Case Definitions for Acute Coronary Heart Disease in Epidemiology and Clinical Research Studies
Luepker, R. V., Apple, F. S., Christenson, R. H., Crow, R. S., Fortmann, S. P., Goff, D. C., Goldberg, R. J., Hand, M. M., Jaffe, A. S., Julian, D. G., et al. (2003) · Circulation · doi:10.1161/01.cir.0000100560.46946.ea · Cited by 810 · see citing works
Self-citation
Impact of Diabetes on Long-Term Prognosis in Patients With Unstable Angina and Non–Q-Wave Myocardial Infarction
Malmberg, K., Yusuf, S., Gerstein, H. C., Brown, J., Zhao, F., Hunt, D. U., Piegas, L. S., Calvin, J. E., Keltai, M., Budaj, A., et al. (2000) · Circulation · doi:10.1161/01.cir.102.9.1014 · Cited by 746 · see citing works
Explaining the Decline in Coronary Heart Disease Mortality in England and Wales Between 1981 and 2000
Ünal, B., Critchley, J., & Capewell, S. (2004) · Circulation · doi:10.1161/01.cir.0000118498.35499.b2 · Cited by 740 · see citing works
Trends in cardiovascular complications of diabetes
Fox, C. S. (2004) · JAMA · doi:10.1001/jama.292.20.2495 · Cited by 626 · see citing works
Self-citation
AN APPROACH TO LONGITUDINAL STUDIES IN A COMMUNITY: THE FRAMINGHAM STUDY
Dawber, T. R., Kannel, W. B., & Lyell, L. P. (1963) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1963.tb13299.x · Cited by 561 · see citing works
Temporal Trends in Coronary Heart Disease Mortality and Sudden Cardiac Death From 1950 to 1999
Fox, C. S., Evans, J. C., Larson, M. G., Kannel, W. B., & Levy, D. A. (2004) · Circulation · doi:10.1161/01.cir.0000136993.34344.41 · Cited by 446 · see citing works
Self-citation
A review of adjusted estimators of attributable risk
Bénichou, J. (2001) · Statistical Methods in Medical Research · doi:10.1177/096228020101000303 · Cited by 440 · see citing works
Influence of Diabetes Mellitus on Clinical Outcome in the Thrombolytic Era of Acute Myocardial Infarction fn1fn1The GUSTO-I study was supported by a combined grant from Bayer, New York, New York; CIBA-Corning, Medfield, Massachusetts; Genetech, South San Francisco, California; ICI Pharmaceuticals, Wilmington, Delaware; and Sanofi Pharmaceuticals, Paris, France.
Mak, K., Moliterno, D. J., Granger, C. B., Miller, D. P., White, H. D., Wilcox, R. G., Califf, R. M., & Topol, E. J. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00118-6 · Cited by 427 · see citing works
Impact of Sirolimus-Eluting Stents on Outcome in Diabetic Patients
Moussa, I. D., Leon, M. B., Baim, D. S., O’Neill, W. W., Popma, J. J., Buchbinder, M., Midwall, J., Simonton, C. A., Keim, E., Wang, P., et al. (2004) · Circulation · doi:10.1161/01.cir.0000129767.45513.71 · Cited by 397 · see citing works
Trends in the Incidence of Type 2 Diabetes Mellitus From the 1970s to the 1990s
Fox, C. S., Pencina, M. J., Meigs, J. B., Vasan, R. S., Levitzky, Y. S., & D’Agostino, R. B. (2006) · Circulation · doi:10.1161/circulationaha.106.613828 · Cited by 378 · see citing works
Self-citation
Diabetes trends in the USA
Skyler, J. S., & Oddo, C. (2002) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.289 · Cited by 360 · see citing works
Explaining the Increase in Coronary Heart Disease Mortality in Beijing Between 1984 and 1999
Critchley, J., Liu, J., Zhao, D. H., Wei, W., & Capewell, S. (2004) · Circulation · doi:10.1161/01.cir.0000140668.91896.ae · Cited by 305 · see citing works
Implications of Diabetes in Patients With Acute Coronary Syndromes The Global Registry of Acute Coronary Events
Franklin, K. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.13.1457 · Cited by 296 · see citing works
Rapid Rise in the Incidence of Type 2 Diabetes From 1987 to 1996
Burke, J. P., Williams, K., GASKILL, S. P., Hazuda, H. P., Haffner, S. M., & D, M. P. S. M. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.13.1450 · Cited by 294 · see citing works
The Continuing Increase of Diabetes in the U.S.
Mokdad, A. H., Ford, E. S., Bowman, B. A., Nelson, D. E., Engelgau, M. M., Vinicor, F., & Marks, J. S. (2001) · Diabetes Care · doi:10.2337/diacare.24.2.412 · Cited by 199 · see citing works
Temporal Trends in BMI Among Adults With Diabetes
Leibson, C. L., Williamson, D. F., Melton, L. J., Palumbo, P. J., Smith, S. A., Ransom, J. E., Schilling, P. L., & Narayan, K. M. V. (2001) · Diabetes Care · doi:10.2337/diacare.24.9.1584 · Cited by 111 · see citing works
Trends in the Mortality Burden Associated With Diabetes Mellitus
Thomas, R. J., Palumbo, P. J., Melton, L. J., Roger, V. L., Ransom, J. E., O’Brien, P. C., & Leibson, C. L. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.4.445 · Cited by 106 · see citing works
Rising prevalence of diabetes: evidence from a Danish pharmacoepidemiological database.
Støvring, H., Andersen, M. T., Beck‐Nielsen, H., Green, A., & Vach, W. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14116-5 · Cited by 93 · see citing works
Impact of the Increasing Burden of Diabetes on Acute Myocardial Infarction in New York City
Fang, J., & Alderman, M. H. (2006) · Diabetes · doi:10.2337/diabetes.55.03.06.db05-1196 · Cited by 66 · see citing works
Type 2 Diabetes and Intravenous Thrombolysis Outcome in the Setting of ST Elevation Myocardial Infarction
Zairis, M. N., Lyras, A. G., Makrygiannis, S. S., Psarogianni, P. K., Adamopoulou, E. N., Handanis, S. M., Papantonakos, A., Argyrakis, S. K., Prekates, A. A., & Foussas, S. G. (2004) · Diabetes Care · doi:10.2337/diacare.27.4.967 · Cited by 44 · see citing works
Sequential Trends in Overall and Cause-Specific Mortality in Diabetic and Nondiabetic Pima Indians
Sievers, M. L., Nelson, R. G., & Bennett, P. H. (1996) · Diabetes Care · doi:10.2337/diacare.19.2.107 · Cited by 36 · see citing works
The decline in coronary heart disease mortality.
Gillum, R. F. (1982) · PubMed · Cited by 18 · see citing works
Bootstrap confidence intervals: when, which, what? A practical guide for medical statisticians
Carpenter (2000) · doi:10.1002/(sici)1097-0258(20000515)19:9

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van Rooij, E., Sutherland, L. B., Thatcher, J. E., DiMaio, J. M., Naseem, R. H., Marshall, W. S., Hill, J. A., & Olson, E. N. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805038105 · Cited by 1,846 · see citing works
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Joint association of TyG index and high sensitivity C-reactive protein with cardiovascular disease: a national cohort study
Cui, C., Liu, L., Qi, Y., Han, N., Xu, H., Wang, Z., Shang, X., Han, T., Zha, Y., Wei, X., et al. (2024) · Cardiovascular Diabetology · doi:10.1186/s12933-024-02244-9 · Cited by 188 · see citing works
Cardiovascular disease and modifiable cardiometabolic risk factors
Cannon, C. P. (2007) · Clinical cornerstone · doi:10.1016/s1098-3597(07)80025-1 · Cited by 175 · see citing works
Intensive glycemic control and cardiovascular disease: an update
Brown, A., Reynolds, L. R., & Bruemmer, D. (2010) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2010.35 · Cited by 173 · see citing works
Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet
Garbow, J. R., Doherty, J. M., Schugar, R. C., Travers, S., Weber, M. L., Wentz, A. E., Ezenwajiaku, N., Cotter, D. G., Brunt, E. M., & Crawford, P. A. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00539.2010 · Cited by 172 · see citing works
High Dietary Fat Selectively Increases Catalase Expression within Cardiac Mitochondria
Rindler, P. M., Plafker, S. M., Szweda, L. I., & Kinter, M. T. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.412890 · Cited by 168 · see citing works
All-Cause and Cardiovascular Mortality in Middle-Aged People With Type 2 Diabetes Compared With People Without Diabetes in a Large U.K. Primary Care Database
Taylor, K., Heneghan, C. J., Farmer, A. A., Fuller, A., Adler, A., Aronson, J. K., & Stevens, R. (2013) · Diabetes Care · doi:10.2337/dc12-1513 · Cited by 169 · see citing works
Assessing the cardio–cerebrovascular safety of vildagliptin: meta‐analysis of adjudicated events from a large Phase III type 2 diabetes population
Schweizer, A., Dejager, S., Foley, J. E., Couturier, A., Ligueros‐Saylan, M., & Kothny, W. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01215.x · Cited by 162 · see citing works
Bilateral Internal Mammary Artery Grafting Enhances Survival in Diabetic Patients
Dorman, M. J., Kurlansky, P. A., Traad, E. A., Galbut, D. L., Zucker, M., & Ebra, G. (2012) · Circulation · doi:10.1161/circulationaha.112.117606 · Cited by 157 · see citing works
VDAC1 functions in Ca2+ homeostasis and cell life and death in health and disease
Shoshan‐Barmatz, V., Krelin, Y., & Shteinfer‐Kuzmine, A. (2017) · Cell Calcium · doi:10.1016/j.ceca.2017.06.007 · Cited by 162 · see citing works
Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome
Kusaka, H., Koibuchi, N., Hasegawa, Y., Ogawa, H., & Kim‐Mitsuyama, S. (2016) · Cardiovascular Diabetology · doi:10.1186/s12933-016-0473-7 · Cited by 159 · see citing works
An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials
Ligueros‐Saylan, M., Foley, J. E., Schweizer, A., Couturier, A., & Kothny, W. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01214.x · Cited by 145 · see citing works
Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts
Alyass, A., Almgren, P., Åkerlund, M., Dushoff, J. G., Isomaa, B., Nilsson, P. M., Tuomilehto, J., Lyssenko, V., Groop, L., & Meyre, D. (2014) · Diabetologia · doi:10.1007/s00125-014-3390-x · Cited by 144 · see citing works
Type 2 diabetes prevalence and incidence among adults in Taiwan during 1999–2004: a national health insurance data set study
Chang, C., Shau, W., Jiang, Y. D., Li, H., Chang, T., Sheu, W. H., Kwok, C., Ho, L. ‐., & Chuang, L. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03007.x · Cited by 142 · see citing works
High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus
Artha, I. M. J. R., Bhargah, A., Dharmawan, N. K., Pande, U. W., Triyana, K. A., Mahariski, P. A., Yuwono, J., Bhargah, V., Prabawa, I. P. Y., Manuaba, I. B. P., et al. (2019) · Vascular Health and Risk Management · doi:10.2147/vhrm.s209830 · Cited by 185 · see citing works
Association Between Tamsulosin and Serious Ophthalmic Adverse Events in Older Men Following Cataract Surgery
Bell, C. M. (2009) · JAMA · doi:10.1001/jama.2009.683 · Cited by 135 · see citing works
MicroRNAs as a therapeutic target for cardiovascular diseases
Mishra, P., Tyagi, N., Kumar, M., & Tyagi, S. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00744.x · Cited by 142 · see citing works
Polychlorinated biphenyls and links to cardiovascular disease
Perkins, J. T., Petriello, M. C., Newsome, B. J., & Hennig, B. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4479-6 · Cited by 132 · see citing works
Pathogenesis of Cardiovascular Disease in Diabetes
Haas, A. V., & McDonnell, M. E. (2018) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2017.10.010 · Cited by 125 · see citing works
Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes
Rudman, N., Gornik, O., & Lauc, G. (2019) · FEBS Letters · doi:10.1002/1873-3468.13495 · Cited by 124 · see citing works
The Impact of Macrophage Insulin Resistance on Advanced Atherosclerotic Plaque Progression
Tabas, I. A., Tall, A. R., & Accili, D. (2010) · Circulation Research · doi:10.1161/circresaha.109.208488 · Cited by 123 · see citing works
Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway
Duan, J., Guan, Y., Mu, F., Guo, C., Zhang, E., Yin, Y., Wei, G., Zhu, Y., Cui, J., Cao, J., et al. (2017) · Scientific Reports · doi:10.1038/srep41491 · Cited by 124 · see citing works
External validity of randomized controlled trials of glycaemic control and vascular disease: how representative are participants?
Saunders, C., Byrne, C. D., Guthrie, B., Lindsay, R. S., McKnight, J. A., Philip, S., Sattar, N. A., Walker, J. J., & Wild, S. H. (2012) · Diabetic Medicine · doi:10.1111/dme.12047 · Cited by 123 · see citing works
Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy.
Lebeche, D., Davidoff, A. J., & Hajjar, R. J. (2008) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio1347 · Cited by 122 · see citing works
Diseases and disorders associated with excess body weight.
Knight, J. A. (2011) · PubMed · Cited by 122 · see citing works
Lipids and lipid management in diabetes
Jaiswal, M., Schinske, A., & Pop‐Busui, R. (2013) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.12.001 · Cited by 117 · see citing works
Glucokinase activators in diabetes management
Coghlan, M. P., & Leighton, B. (2008) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.17.2.145 · Cited by 112 · see citing works
Cardiovascular risk factors burden in Saudi Arabia: The Africa Middle East Cardiovascular Epidemiological (ACE) study
Ahmed, A. M., Hersi, A. S., Mashhoud, W. M., Arafah, M., Abreu, P. C., Alrowaily, M., & Al-Mallah, M. H. (2017) · Journal of the Saudi Heart Association · doi:10.1016/j.jsha.2017.03.004 · Cited by 112 · see citing works
Cardiovascular disease and glycemic control in type 2 diabetes: now that the dust is settling from large clinical trials
Giorgino, F., Leonardini, A., & Laviola, L. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12044 · Cited by 112 · see citing works
Genetics of Type 2 Diabetes: Implications from Large-Scale Studies
DeForest, N., & Majithia, A. R. (2022) · Current Diabetes Reports · doi:10.1007/s11892-022-01462-3 · Cited by 112 · see citing works
Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways
Kang, S., Chemaly, E. R., Hajjar, R. J., & Lebeche, D. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.200022 · Cited by 108 · see citing works
Metabolic Health Reduces Risk of Obesity-Related Cancer in Framingham Study Adults
Moore, L. L., Chadid, S., Singer, M. R., Kreger, B. E., & Denis, G. V. (2014) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-0240 · Cited by 107 · see citing works
Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial
Holman, R. R., Bethel, M. A., George, J. T., Sourij, H., Doran, Z., Keenan, J. F., Khurmi, N. S., Mentz, R. J., Oulhaj, A., Buse, J. B., et al. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.12.009 · Cited by 105 · see citing works
Self-citation
Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia–reperfusion injury
Chinda, K., Palee, S., Surinkaew, S., Phimphilai, M., Chattipakorn, S. C., & Chattipakorn, N. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.01.011 · Cited by 103 · see citing works
Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease
Schugar, R. C., & Crawford, P. A. (2012) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3283547157 · Cited by 102 · see citing works
Dietary Patterns and Cardiovascular Disease Risk in People with Type 2 Diabetes
Archundia Herrera, M. C., Subhan, F. B., & Chan, C. B. (2017) · Current Obesity Reports · doi:10.1007/s13679-017-0284-5 · Cited by 98 · see citing works
A comparison of effects of DPP-4 inhibitor and SGLT2 inhibitor on lipid profile in patients with type 2 diabetes
Cha, S., Park, Y., Yun, J., Lim, T., Song, K., Yoo, K., Ahn, Y., & Ko, S. (2017) · Lipids in Health and Disease · doi:10.1186/s12944-017-0443-4 · Cited by 100 · see citing works
Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium mice model
Huang, S., Zhang, L., Song, J., Wang, Z., Huang, X., Guo, Z., Chen, F., & Zhao, X. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27117 · Cited by 100 · see citing works
Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo
Bentley–Lewis, R., Aguilar, D. A., Riddle, M. C., Claggett, B. L., Díaz, R., Dickstein, K., Gerstein, H. C., Johnston, P., Køber, L., Lawson, F. C., et al. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.02.002 · Cited by 96 · see citing works
Cytokines and inflammation in adipogenesis: an updated review
Jiang, N., Yao, L., Shu, T., & Wang, J. (2018) · Frontiers of Medicine · doi:10.1007/s11684-018-0625-0 · Cited by 98 · see citing works
Aspirin for the Primary Prevention of Cardiovascular Events
Calvin, A. D., Aggarwal, N. R., Murad, M. H., Shi, Q., Elamin, M. B., Geske, J. B., Fernández-Balsells, M., Albuquerque, F. N., Lampropulos, J. F., Erwin, P. J., et al. (2009) · Diabetes Care · doi:10.2337/dc09-1297 · Cited by 98 · see citing works
Impact of Hypoglycemia Associated With Antihyperglycemic Medications on Vascular Risks in Veterans With Type 2 Diabetes
Zhao, Y., Campbell, C. R., Fonseca, V. A., & Shi, L. (2012) · Diabetes Care · doi:10.2337/dc11-2048 · Cited by 94 · see citing works
Oculomics: Current concepts and evidence
Zhu, Z., Wang, Y., Qi, Z., Hu, W., Zhang, X., Wagner, S. K., Wang, Y., Ran, A. R., Ong, J., Waisberg, E., et al. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101350 · Cited by 94 · see citing works
Trends in the Prevalence and Comorbidities of Diabetes Mellitus in Nursing Home Residents in the United States: 1995–2004
Zhang, X., Decker, F. H., Luo, H., Geiss, L. S., Pearson, W. S., SAADDINE, J. B., Gregg, E. W., & Albright, A. L. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02786.x · Cited by 93 · see citing works
Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes
Patel, S. K., Wai, B., Ord, M., MacIsaac, R. J., Grant, S., Velkoska, E., Panagiotopoulos, S., Jerums, G., Srivastava, P., & Burrell, L. M. (2011) · American Journal of Hypertension · doi:10.1038/ajh.2011.188 · Cited by 90 · see citing works
Diabetes care in hospital—the impact of a dedicated inpatient care team
Flanagan, D., Moore, E., Baker, S., Wright, D. E., & Lynch, P. (2008) · Diabetic Medicine · doi:10.1111/j.1464-5491.2007.02326.x · Cited by 90 · see citing works
MicroRNA 21 Inhibits Left Ventricular Remodeling in the Early Phase of Rat Model with Ischemia-reperfusion Injury by Suppressing Cell Apoptosis
Qin, Y., Yu, Y., Dong, H., Bian, X., Guo, X., & Dong, S. (2012) · International Journal of Medical Sciences · doi:10.7150/ijms.4514 · Cited by 88 · see citing works
Dyslipidemia in diabetes mellitus and cardiovascular disease
Warraich, H. J., & Rana, J. S. (2017) · Cardiovascular Endocrinology · doi:10.1097/xce.0000000000000120 · Cited by 91 · see citing works
Emerging role of chemokine CC motif ligand 4 related mechanisms in diabetes mellitus and cardiovascular disease: friends or foes?
Chang, T., & Chen, J. (2016) · Cardiovascular Diabetology · doi:10.1186/s12933-016-0439-9 · Cited by 87 · see citing works
Cardiovascular consequences of drugs used for the treatment of diabetes: potential promise of incretin—based therapies
Ban, K., Hui, S., Drucker, D. J., & Husain, M. (2009) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2009.04.001 · Cited by 86 · see citing works
S100 proteins in atherosclerosis
Xiao, X., Chen, Y., Qu, S.-L., Shao, Y.-D., Zhou, C.-Y., Chao, R., Huang, L., & Zhang, C. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.11.019 · Cited by 86 · see citing works
Coronary artery bypass grafting in diabetics: A growing health care cost crisis
Raza, S., Sabik, J. F., Ainkaran, P., & Blackstone, E. H. (2015) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2015.03.041 · Cited by 86 · see citing works
Dose-response relationship between polycyclic aromatic hydrocarbon metabolites and risk of diabetes in the general Chinese population
Yang, L., Zhou, Y., Sun, H., Lai, H., Liu, C., Yan, K., Yuan, J., Wu, T., Chen, W., & Zhang, X. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2014.08.012 · Cited by 85 · see citing works
Metformin action on AMP‐activated protein kinase: a translational research approach to understanding a potential new therapeutic target
Boyle, J. G., Salt, I. P., & McKay, G. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03098.x · Cited by 82 · see citing works
Prevalence of diabetes in Brazil over time: a systematic review with meta-analysis
Teló, G. H., Cureau, F. V., de Souza, M. S., Andrade, T. D. S., Copês, F. S., & Schaan, B. D. (2016) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-016-0181-1 · Cited by 81 · see citing works
Vorapaxar in Patients With Diabetes Mellitus and Previous Myocardial Infarction: Findings From the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events-TIMI 50 Trial
Cavender, M. A., Scirica, B. M., Bonaca, M. P., Angiolillo, D. J., Dalby, A. J., Dellborg, M., Morais, J., Murphy, S. A., Ophuis, T. O., Tendera, M., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.013774 · Cited by 80 · see citing works
Lifestyle and Cardiometabolic Risk in Adults with Type 1 Diabetes: A Review
Leroux, C., Brazeau, A., Gingras, V., Desjardins, K., Strychar, I. M., & RABASA-LHORET, R. P. R. (2014) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.08.268 · Cited by 80 · see citing works
Gene × Environment Interactions in Type 2 Diabetes
Franks, P. W. (2011) · Current Diabetes Reports · doi:10.1007/s11892-011-0224-9 · Cited by 78 · see citing works
Clinical Patterns of Obstructive Sleep Apnea and Its Comorbid Conditions: A Data Mining Approach
Huang, Q. R., Qin, Z., Zhang, S., & Chow, C. M. (2008) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27348 · Cited by 80 · see citing works
Trends in the control of risk factors for cardiovascular disease among adults with diagnosed diabetes: Findings from the National Health and Nutrition Examination Survey 1999-2008*
Ford, E. S. (2011) · Journal of Diabetes · doi:10.1111/j.1753-0407.2011.00148.x · Cited by 79 · see citing works
Diabetes prevention: global health policy and perspectives from the ground
Bergman, M., Buysschaert, M., Schwarz, P. E. H., Albright, A. L., Narayan, K. M. V., & Yach, D. (2012) · Diabetes Management · doi:10.2217/dmt.12.34 · Cited by 80 · see citing works
Cardiovascular Disease in Type 2 Diabetes: A Review of Sex-Related Differences in Predisposition and Prevention
Al-Salameh, A., Chanson, P., Bucher, S., Ringa, V., & Becquemont, L. (2019) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.08.007 · Cited by 77 · see citing works
Population Health Management for Diabetes: Health Care System-Level Approaches for Improving Quality and Addressing Disparities
Schmittdiel, J. A., Gopalan, A., Lin, M. W., Banerjee, S., Chau, C. V., & Adams, A. S. (2017) · Current Diabetes Reports · doi:10.1007/s11892-017-0858-3 · Cited by 78 · see citing works
Epidemiology, Traditional and Novel Risk Factors in Coronary Artery Disease
Mack, M. C., & Gopal, A. (2015) · Heart Failure Clinics · doi:10.1016/j.hfc.2015.08.002 · Cited by 76 · see citing works
Protective Role of Antioxidants in Diabetes-Induced Cardiac Dysfunction
Vassort, G., & Turan, B. (2010) · Cardiovascular Toxicology · doi:10.1007/s12012-010-9064-0 · Cited by 75 · see citing works

The Framingham Study, Diabetes Mellitus and Cardiovascular Disease: Turning Back the Clock
Kengne, A. P., Turnbull, F., & MacMahon, S. W. (2010) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2010.02.010 · Cited by 62 · see citing works
Trends in cardiovascular complications of diabetes
Fox, C. S. (2004) · JAMA · doi:10.1001/jama.292.20.2495 · Cited by 626 · see citing works
Self-citation
Diabetes Trend and Impact on Risk of Cardiovascular Disease in Middle-Aged Japanese People – The CIRCS Study –
Hayama‐Terada, M., Muraki, I., Imano, H., Kiyama, M., Okada, T., Yamagishi, K., Cui, R., Ohira, T., Umesawa, M., Sankai, T., et al. (2016) · Circulation Journal · doi:10.1253/circj.cj-16-0549 · Cited by 16 · see citing works
Cardiovascular risk and all-cause mortality attributable to diabetes: Tehran lipid and glucose study.
Bozorgmanesh, M., Hadaegh, F., Sheikholeslami, F. H., & Azizi, F. (2012) · PubMed · doi:10.3275/7728 · Cited by 21 · see citing works
Moving Toward “Precision” Medicine: Can We Tailor Diabetes Therapy to Patients’ Differential Risks of Future Cardiovascular Disease?
Clark, K. A. A., & Morris, A. A. (2022) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2022.12.002

Authors: Fox, C. S., Coady, S., Sorlie, P. D., D’Agostino, R. B., Pencina, M. J., Vasan, R. S., Meigs, J. B., Levy, D., & Savage, P. J.
Affiliations: Boston University (US)
ORCID: Fox, Caroline S.
D’Agostino, Ralph B.
Pencina, Michael J.
Vasan, Ramachandran S.
Meigs, James B.
Levy, Daniel
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-03-27
Volume: 115
Issue: 12
Pages: 1544-1550
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.106.658948
OpenAlex: W2055416829
Cited by: 656
References: 38
Citations by year: 2026: 11 · 2025: 15 · 2024: 20 · 2023: 19 · 2022: 35 · 2021: 25 · 2020: 27 · 2019: 23 · 2018: 32 · 2017: 38 · 2016: 42 · 2015: 46 · 2014: 49 · 2013: 35 · 2012: 52
FWCI: 33.94
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01hc25195-41-0-1)
U.S. Public Health Service (5K24H004334)
National Heart, Lung, and Blood Institute (N01‐HC25195)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: diabetes mellitus, cardiovascular disease, population attributable risk, cardiovascular risk factors, temporal trends, Framingham Heart Study, middle-aged adults, diabetes prevention, cardiovascular risk management
MeSH terms: Blood Glucose, Cardiovascular Diseases, Diabetes Mellitus, Female, Humans, Hypertension, Male, Middle Aged, Obesity, Risk, Risk Factors, Smoking, United States, Cohort Studies, Incidence, Proportional Hazards Models, Diabetes Complications

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Increasing Cardiovascular Disease Burden Due to Diabetes Mellitus: The Framingham Heart Study

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