Cited by 2,380Mindfulness and Compassion InterventionsReligion, Spirituality, and PsychologyPsychological Well-being and Life Satisfaction

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Meditation Programs for Psychological Stress and Well-being: A Systematic Review and Meta-analysis

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Abstract

IMPORTANCE: Many people meditate to reduce psychological stress and stress-related health problems. To counsel people appropriately, clinicians need to know what the evidence says about the health benefits of meditation. OBJECTIVE: To determine the efficacy of meditation programs in improving stress-related outcomes (anxiety, depression, stress/distress, positive mood, mental health-related quality of life, attention, substance use, eating habits, sleep, pain, and weight) in diverse adult clinical populations. EVIDENCE REVIEW: We identified randomized clinical trials with active controls for placebo effects through November 2012 from MEDLINE, PsycINFO, EMBASE, PsycArticles, Scopus, CINAHL, AMED, the Cochrane Library, and hand searches. Two independent reviewers screened citations and extracted data. We graded the strength of evidence using 4 domains (risk of bias, precision, directness, and consistency) and determined the magnitude and direction of effect by calculating the relative difference between groups in change from baseline. When possible, we conducted meta-analyses using standardized mean differences to obtain aggregate estimates of effect size with 95% confidence intervals. FINDINGS: After reviewing 18 753 citations, we included 47 trials with 3515 participants. Mindfulness meditation programs had moderate evidence of improved anxiety (effect size, 0.38 [95% CI, 0.12-0.64] at 8 weeks and 0.22 [0.02-0.43] at 3-6 months), depression (0.30 [0.00-0.59] at 8 weeks and 0.23 [0.05-0.42] at 3-6 months), and pain (0.33 [0.03- 0.62]) and low evidence of improved stress/distress and mental health-related quality of life. We found low evidence of no effect or insufficient evidence of any effect of meditation programs on positive mood, attention, substance use, eating habits, sleep, and weight. We found no evidence that meditation programs were better than any active treatment (ie, drugs, exercise, and other behavioral therapies). CONCLUSIONS AND RELEVANCE: Clinicians should be aware that meditation programs can result in small to moderate reductions of multiple negative dimensions of psychological stress. Thus, clinicians should be prepared to talk with their patients about the role that a meditation program could have in addressing psychological stress. Stronger study designs are needed to determine the effects of meditation programs in improving the positive dimensions of mental health and stress-related behavior.

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Research works printed but not linked: 2

  1. [25]Travis FGS Stixrud W ADHD, Brain Functioning, and Transcendental Meditation Practice Mind & Brain, The Journal of Psychiatry 2011 73 81
  2. [30]Methods Guide for Conducting Comparative Effectiveness Reviews Rockville, MD Agency for Healthcare Research and Quality 8 2007 AHRQ Publication No. 10(11)-EHC063-EF 21433403

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Metadata

Authors
Goyal, M., Singh, S., Sibinga, E. M. S., Gould, N. F., Rowland-Seymour, A., Sharma, R., Berger, Z., Sleicher, D., Maron, D. D., Shihab, H. M., Ranasinghe, P. D., Linn, S., Saha, S., Bass, E. B., & Haythornthwaite, J. A.
Affiliations
Johns Hopkins University (US)
Corresponding author
Goyal, Madhav
Venue
JAMA Internal Medicine
Published
2014-03-01
Volume
174
Issue
3
Pages
357
ISSN
2168-6106 (ISSN-L)
OpenAlex
W2084605964
Cited by
2,380
References
94
Citations by year
2026: 200 · 2025: 246 · 2024: 163 · 2023: 159 · 2022: 187 · 2021: 188 · 2020: 311 · 2019: 203 · 2018: 178 · 2017: 177 · 2016: 175 · 2015: 135 · 2014: 57
FWCI
213.98
Type
journal article
Language
en
Open access
Locations
  • JAMA Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (UL1TR001079)
  • U.S. Public Health Service (HHSA-290-2007-10061)
  • National Center for Advancing Translational Sciences
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (T32HD052459)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Social Sciences › Health › Religion, Spirituality, and Psychology
  • Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
Keywords
meditation program, mindfulness meditation, psychological stress, anxiety, depression, mental health-related quality of life, pain, positive mood, sleep, substance use, dietary habits, attention, weight, well-being, stress-related health problems, treatment efficacy, placebo effect, risk of bias
MeSH terms
Adult, Affect, Anxiety, Depression, Humans, Quality of Life, Stress, Psychological, Meditation

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