Soft Robotics
Open accessAbstract
This description of “soft robotics” is not intended to be a conventional review, in the sense of a comprehensive technical summary of a developing field. Rather, its objective is to describe soft robotics as a new field—one that offers opportunities to chemists and materials scientists who like to make “things” and to work with macroscopic objects that move and exert force. It will give one (personal) view of what soft actuators and robots are, and how this class of soft devices fits into the more highly developed field of conventional “hard” robotics. It will also suggest how and why soft robotics is more than simply a minor technical “tweak” on hard robotics and propose a unique role for chemistry, and materials science, in this field. Soft robotics is, at its core, intellectually and technologically different from hard robotics, both because it has different objectives and uses and because it relies on the properties of materials to assume many of the roles played by sensors, actuators, and controllers in hard robotics.
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Combining soft robotics with e-skin can provide safe, light, low-complexity actuation without the high cognitive strain of rigid heavy counterparts.
“The combination of soft robotics with e-skin can additionally provide the user with a safe, light, and low complexity mode of actuation without the high cognitive strain associated with its rigid and heavy counterpart.[33–35]”
From Flexible Electronics and Devices as Human–Machine Interfaces for Medical Robotics (2022) · cites this paper as [34]
In “Simplicity and Lower Cost” and “Other Characteristics: Light Weight,” the paper describes simpler control and lighter soft actuators than hard counterparts. “Biomedical Uses” describes safe interaction with humans. These passages do not establish that combining soft robotics with e-skin reduces users’ cognitive strain. (LLM, conf=0.87)
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Giorgio-Serchi, F., & Weymouth, G. D. (2016) · Biosystems & biorobotics · doi:10.1007/978-3-319-46460-2_6 · Cited by 23 · see citing works
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Multimodal Soft Robotic Actuation and Locomotion
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Magneto‐Mechanical Metamaterials with Widely Tunable Mechanical Properties and Acoustic Bandgaps
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“When incorporated into metamaterials, the structures and their corresponding properties can change in response to stimuli, making them very attractive in applications such as deployable structures (26, 27), soft robotics (28, 29), and tunable acoustic metastructures (23, 30).”
BackgroundSoft electromagnetic actuators
Mao, G., Drack, M., Karami‐Mosammam, M., Wirthl, D., Stockinger, T., Schwödiauer, R., & Kaltenbrunner, M. (2020) · Science Advances · doi:10.1126/sciadv.abc0251 · Cited by 228 · see citing works
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Self-citationMonolithic shape-programmable dielectric liquid crystal elastomer actuators
Davidson, Z. S., Shahsavan, H., Aghakhani, A., Guo, Y., Hines, L., Xia, Y., Yang, S. M., & Sitti, M. (2019) · Science Advances · doi:10.1126/sciadv.aay0855 · Cited by 225 · see citing works
Machine Learning for Soft Robotic Sensing and Control
Chin, K., Hellebrekers, T., & Majidi, C. (2020) · Advanced Intelligent Systems · doi:10.1002/aisy.201900171 · Cited by 215 · see citing works
Architectural Code for Rubber Elasticity: From Supersoft to Superfirm Materials
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Liu, M., Wang, Z., Liu, P., Wang, Z., Yao, H., & Yao, X. (2019) · Science Advances · doi:10.1126/sciadv.aaw5643 · Cited by 203 · see citing works
Yang, Y., Vella, K., & Holmes, D. P. (2021) · Science Robotics · doi:10.1126/scirobotics.abd6426 · Cited by 207 · see citing works
Magnetically Controlled Soft Robotics Utilizing Elastomers and Gels in Actuation: A Review
Chung, H., Parsons, A. M., & Zheng, L. (2020) · Advanced Intelligent Systems · doi:10.1002/aisy.202000186 · Cited by 197 · see citing works
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A Soft Transporter Robot Fueled by Light
da Cunha, M. P., Ambergen, S., Debije, M. G., Homburg, E. F. G. A., den Toonder, J. M. J., & Schenning, A. P. H. J. (2020) · Advanced Science · doi:10.1002/advs.201902842 · Cited by 190 · see citing works
Progress and Roadmap for Intelligent Self‐Healing Materials in Autonomous Robotics
Tan, Y. J., Susanto, G. J., Ali, H. P. A., & Tee, B. C. K. (2020) · Advanced Materials · doi:10.1002/adma.202002800 · Cited by 191 · see citing works
Yang, X. J., Chen, Y., Zhang, X., Xue, P., Lv, P., Yang, J., Wang, L., & Feng, W. (2022) · Nano Today · doi:10.1016/j.nantod.2022.101419 · Cited by 187 · see citing works
Soft Robots for Ocean Exploration and Offshore Operations: A Perspective
Aracri, S., Giorgio-Serchi, F., Suaria, G., Sayed, M. E., Nemitz, M. P., Mahon, S. T., & Stokes, A. A. (2021) · Soft Robotics · doi:10.1089/soro.2020.0011 · Cited by 181 · see citing works
“Pneumatic soft actuators, particularly ‘‘Pneunets,’’(14) are very popular among soft robotic researchers for many different applications, despite their low efficiency.(155) Analysis of PneuNet actuators with various wall thicknesses and different soft materials shows that the efficiency of these soft actuators lies in…”
BackgroundWearable and Implantable Soft Robots
Yin, S., Yao, D. R., Song, Y., Heng, W., Ma, X., Han, H., & Gao, W. F. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00513 · Cited by 179 · see citing works
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Tough, Self‐Healing Hydrogels Capable of Ultrafast Shape Changing
Jiang, Z., Diggle, B., Shackleford, I. C. G., & Connal, L. A. (2019) · Advanced Materials · doi:10.1002/adma.201904956 · Cited by 172 · see citing works
Soft Materials Driven by Photothermal Effect and Their Applications
Bisoyi, H. K., Urbas, A. M., & Li, Q. (2018) · Advanced Optical Materials · doi:10.1002/adom.201800458 · Cited by 171 · see citing works
3D printing of resilient biogels for omnidirectional and exteroceptive soft actuators
Heiden, A., Preninger, D., Lehner, L. E., Baumgartner, M., Drack, M., Woritzka, E., Schiller, D., Gerstmayr, R., Hartmann, F., & Kaltenbrunner, M. (2022) · Science Robotics · doi:10.1126/scirobotics.abk2119 · Cited by 170 · see citing works
Zadan, M., Patel, D. K., Sabelhaus, A. P., Liao, J., Wertz, A., Yao, L., & Majidi, C. (2022) · Advanced Materials · doi:10.1002/adma.202200857 · Cited by 170 · see citing works
Strong, Self‐Healable, and Recyclable Visible‐Light‐Responsive Hydrogel Actuators
Jiang, Z., Tan, M. L., Taheri, M., Yan, Q., Tsuzuki, T., Gardiner, M. G., Diggle, B., & Connal, L. A. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201916058 · Cited by 168 · see citing works
A Review of Magnetic Elastomers and Their Role in Soft Robotics
Bira, N., Dhagat, P., & Davidson, J. R. (2020) · Frontiers in Robotics and AI · doi:10.3389/frobt.2020.588391 · Cited by 168 · see citing works
“A challenging area for soft robotics is reducing robotic tethering, or the reliance of a soft robot on a base station for power, pressure, and other forms of regulation (Rus and Tolley, 2015; Whitesides, 2018).”
BackgroundDesigning Molecular Photoswitches for Soft Materials Applications
Boelke, J., & Hecht, S. (2019) · Advanced Optical Materials · doi:10.1002/adom.201900404 · Cited by 165 · see citing works
Liquid‐Crystalline Soft Actuators with Switchable Thermal Reprogrammability
Wu, Y., Yang, Y., Qian, X., Chen, Q., Wei, Y., & Ji, Y. J. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201915694 · Cited by 164 · see citing works
Microfluidics‐Based Biomaterials and Biodevices
Dong, R., Liu, Y., Mou, L., Deng, J., & Jiang, X. (2018) · Advanced Materials · doi:10.1002/adma.201805033 · Cited by 158 · see citing works
Robotic surfaces with reversible, spatiotemporal control for shape morphing and object manipulation
Liu, K., Hacker, F., & Daraio, C. (2021) · Science Robotics · doi:10.1126/scirobotics.abf5116 · Cited by 159 · see citing works
Hybrid Jamming for Bioinspired Soft Robotic Fingers
Yang, Y., Zhang, Y., Kan, Z., Zeng, J., & Wang, M. Y. (2019) · Soft Robotics · doi:10.1089/soro.2019.0093 · Cited by 158 · see citing works
Dual-Gel 4D Printing of Bioinspired Tubes
Liu, J., Erol, O., Pantula, A., Liu, W., Jiang, Z., Kobayashi, K., Chatterjee, D., Hibino, N., Romer, L. H., Kang, S. H., et al. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b17218 · Cited by 156 · see citing works
Soft robotic steerable microcatheter for the endovascular treatment of cerebral disorders
Gopesh, T., Wen, J. H., Santiago-Dieppa, D. R., Yan, B., Pannell, J. S., Khalessi, A. A., Norbash, A., & Friend, J. R. (2021) · Science Robotics · doi:10.1126/scirobotics.abf0601 · Cited by 154 · see citing works
Advances in 4D printing of liquid crystalline elastomers: materials, techniques, and applications
Guan, Z., Wang, L., & Bae, J. (2022) · Materials Horizons · doi:10.1039/d2mh00232a · Cited by 154 · see citing works
Liquid Crystal Polymer‐Based Soft Robots
Xiao, Y., Jiang, Z., & Zhao, Y. (2020) · Advanced Intelligent Systems · doi:10.1002/aisy.202000148 · Cited by 152 · see citing works
Liu, Y., Wang, W., Gu, K., Yao, J., Shao, Z., & Chen, X. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c09006 · Cited by 149 · see citing works
Stretchable Multiresponsive Hydrogel with Actuatable, Shape Memory, and Self‐Healing Properties
Zhang, F., Xiong, L., Ai, Y., Liang, Z., & Liang, Q. (2018) · Advanced Science · doi:10.1002/advs.201800450 · Cited by 148 · see citing works
Bioinspired Soft Robotic Caterpillar with Cardiomyocyte Drivers
Sun, L., Chen, Z., Bian, F., & Zhao, Y. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201907820 · Cited by 147 · see citing works
Coupled liquid crystalline oscillators in Huygens’ synchrony
Vantomme, G., Elands, L. C. M., Gelebart, A. H., Meijer, E. W., POGROMSKY, A. Y., Nijmeijer, H., & Broer, D. J. (2021) · Nature Materials · doi:10.1038/s41563-021-00931-6 · Cited by 142 · see citing works
Living Materials Herald a New Era in Soft Robotics
Appiah, C., Arndt, C., Siemsen, K., Heitmann, A., Staubitz, A., & Selhuber‐Unkel, C. (2019) · Advanced Materials · doi:10.1002/adma.201807747 · Cited by 140 · see citing works
Gao, W. M., Lei, Z., Zhang, C., Liu, X., & Chen, Y. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202104071 · Cited by 140 · see citing works
4D printing in biomedical applications: emerging trends and technologies
Agarwal, T., Hann, S.-Y., Chiesa, I., Cui, H., Celikkin, N., Micalizzi, S., Barbetta, A., Costantini, M., Esworthy, T. J., Zhang, L. G., et al. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb01335a · Cited by 131 · see citing works
Low Melting Point Alloys Enabled Stiffness Tunable Advanced Materials
Hao, Y., Gao, J., Lv, Y., & Liu, J. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202201942 · Cited by 129 · see citing works
Autonomous Soft Robots Empowered by Chemical Reaction Networks
Fusi, G., Giudice, D. D., Skarsetz, O., Stefano, S. D., & Walther, A. (2022) · Advanced Materials · doi:10.1002/adma.202209870 · Cited by 129 · see citing works
Troyano, J., Carné‐Sánchez, A., & Maspoch, D. (2019) · Advanced Materials · doi:10.1002/adma.201808235 · Cited by 127 · see citing works
Recent Advances on Underwater Soft Robots
Qu, J., Xu, Y., Li, Z., Yu, Z., Mao, B., Wang, Y., Wang, Z., Fan, Q., Qian, X., Zhang, M., et al. (2023) · Advanced Intelligent Systems · doi:10.1002/aisy.202300299 · Cited by 129 · see citing works
Snapping for high-speed and high-efficient butterfly stroke–like soft swimmer
Chi, Y., Hong, Y., Zhao, Y., Li, Y., & Yin, J. (2022) · Science Advances · doi:10.1126/sciadv.add3788 · Cited by 126 · see citing works
Bioinspired footed soft robot with unidirectional all-terrain mobility
Wang, X., Yang, B., Tan, D., Li, Q., Song, B., Wu, Z., del Campo, A., Kappl, M., Wang, Z., Gorb, S. N., et al. (2020) · Materials Today · doi:10.1016/j.mattod.2019.12.028 · Cited by 125 · see citing works
Indirect 3D and 4D Printing of Soft Robotic Microstructures
Marco, C. D., Alcantara, C., Kim, S., Vangosa, F. B., Kadioglu, A., Bernardis, G. D., Chen, X., Marano, C., Nelson, B. J., & Pané, S. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201900332 · Cited by 123 · see citing works
High‐Strain Peano‐HASEL Actuators
Wang, X., Mitchell, S. K., Rumley, E. H., Rothemund, P., & Keplinger, C. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201908821 · Cited by 123 · see citing works
Topoarchitected polymer networks expand the space of material properties
Liu, X., Wu, J., Qiao, K., Liu, G., Wang, Z., Lu, T., Suo, Z., & Hu, J. Q. (2022) · Nature Communications · doi:10.1038/s41467-022-29245-0 · Cited by 122 · see citing works
Soft Materials and Devices Enabling Sensorimotor Functions in Soft Robots
Su, J., He, K., Li, Y., Tu, J., & Chen, X. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00906 · Cited by 118 · see citing works
Sajjad, R., Chauhdary, S. T., Anwar, M. T., Zahid, A., Khosa, A. A., Imran, M., & Sajjad, M. H. (2023) · Advanced Industrial and Engineering Polymer Research · doi:10.1016/j.aiepr.2023.08.002 · Cited by 126 · see citing works
Reinforced Gels and Elastomers for Biomedical and Soft Robotics Applications
Zhalmuratova, D., & Chung, H. (2020) · ACS Applied Polymer Materials · doi:10.1021/acsapm.9b01078 · Cited by 116 · see citing works
From Bioinspiration to Computer Generation: Developments in Autonomous Soft Robot Design
Pinskier, J., & Howard, D. (2021) · Advanced Intelligent Systems · doi:10.1002/aisy.202100086 · Cited by 113 · see citing works
Morphing matter: from mechanical principles to robotic applications
Yang, X., Zhou, Y., Zhao, H., Huang, W., Wang, Y., Hsia, K. J., & Liu, M. (2023) · Soft Science · doi:10.20517/ss.2023.42 · Cited by 114 · see citing works
Sankar, S., Wenyu, C., Zhang, J., Slepyan, A., Iskarous, M. M., Greene, R. J., DeBrabander, R., Chen, J., Gupta, A., & Thakor, N. V. (2025) · Science Advances · doi:10.1126/sciadv.adr9300 · Cited by 109 · see citing works
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Sensorized Reconfigurable Soft Robotic Gripper System for Automated Food Handling
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“based actuators and 3D-printed actuators [11]–[13] are also manufactured at lower production cost than conventional rigid”
Background3D-Printed Self-Healing Elastomers for Modular Soft Robotics
Gomez, E. F., Wanasinghe, S. V., Flynn, A. E., Dodo, O. J., Sparks, J. L., Baldwin, L. A., Tabor, C. E., Durstock, M. F., Konkolewicz, D., & Thrasher, C. J. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c06419 · Cited by 104 · see citing works
A 3D Printed Modular Soft Gripper Integrated With Metamaterials for Conformal Grasping
Tawk, C., Mutlu, R., & Alıcı, G. (2022) · Frontiers in Robotics and AI · doi:10.3389/frobt.2021.799230 · Cited by 103 · see citing works
“Soft robots are characterized by their adaptability, conformability, agility, and durability (Whitesides, 2018) compared to their conventional rigid and stiff counterparts (Alici, 2018).”
BackgroundBottlebrush Bridge between Soft Gels and Firm Tissues
Keith, A. N., Vatankhah‐Varnosfaderani, M., Clair, C., Fahimipour, F., Dashtimoghadam, E., Lallam, A., Sztucki, M., Ivanov, D. A., Liang, H., Dobrynin, A. V., et al. (2020) · ACS Central Science · doi:10.1021/acscentsci.9b01216 · Cited by 101 · see citing works
A Functioning Macroscopic “Rubik's Cube” Assembled via Controllable Dynamic Covalent Interactions
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Regulation of Hard Segment Cluster Structures for High‐performance Poly(urethane‐urea) Elastomers
Qin, J., Chen, Y., Guo, X., Huang, Y., Chen, G., Zhang, Q., He, G., Zhu, S., Ruan, X., & Zhu, H. (2024) · Advanced Science · doi:10.1002/advs.202400255 · Cited by 101 · see citing works
He, Z., Shen, J., Lan, M., & Gu, H. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb00374h · Cited by 100 · see citing works
The neuromechanics of animal locomotion: From biology to robotics and back
Ramdya, P., & Ijspeert, A. J. (2023) · Science Robotics · doi:10.1126/scirobotics.adg0279 · Cited by 92 · see citing works
Origami Biosystems: 3D Assembly Methods for Biomedical Applications
Quiñones, V. A. B., Zhu, H. Y., Solovev, A. A., Mei, Y., & Gracias, D. H. (2018) · Advanced Biosystems · doi:10.1002/adbi.201800230 · Cited by 98 · see citing works
- Authors
- Whitesides, G. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- Whitesides, George M.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2018-03-08
- Volume
- 57
- Issue
- 16
- Pages
- 4258-4273
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W4211124276
- Semantic Scholar
- 4899ed6fef8ac75874a202e3458e4a2c1151f926
- Cited by
- 850
- References
- 98
- Citations by year
- 2026: 77 · 2025: 127 · 2024: 121 · 2023: 140 · 2022: 113 · 2021: 113 · 2020: 88 · 2019: 57 · 2018: 14
- FWCI
- 5.54
- Type
- journal article
- Language
- en
- Open access
- green
- www.osti.gov
- Locations
- Angewandte Chemie International Edition (publishedVersion)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- Funders
- National Science Foundation (1420570)
- U.S. Department of Energy (# ER45852, DESC0000989)
- Defense Advanced Research Projects Agency
- Materials Research Science and Engineering Center, Harvard University (DMR- 1420570, 1420570)
- Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University
- Division of Materials Research (DMR 14–20570, 1420570)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Soft Robotics and Applications
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Physical Sciences › Engineering › Biomedical Engineering › Robotic Locomotion and Control
- Keywords
- soft robotics, soft actuators
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