The association between COVID ‐19, personal wellbeing, depression, and suicide risk factors in Australian autistic adults
Open accessAbstract
The COVID-19 pandemic has had a significant impact on the mental health and wellbeing of the world's population, with particularly negative effects on vulnerable populations, including autistic people. Although some consensus regarding specific impact on aspects of wellbeing and mental health in autism is starting to emerge, it is unclear whether the pandemic has increased suicide risk. The goals of this study were to examine (a) potential associations between COVID-19 impact and depression, personal wellbeing, and suicide risk factors in Australian autistic adults and (b) age and gender effects. The COVID-19 Impact Scale (CIS), Personal Wellbeing Index, Patient Health Questionnaire, and the Suicide Behavior Questionnaire, Revised (SBQ-R), were administered to 111 autistic adults aged 20 to 71 years during the second wave of the COVID-19 pandemic in Australia. COVID-19 impact showed small associations with poorer personal wellbeing (r = -0.224, p = 0.023, [-0.409, -0.016]) and higher depressive symptoms (r = 0.268, p = 0.006, [0.056, 0.445]) and was not associated with the SBQ-R suicide risk score (r = 0.081, p = 0.418, [-0.118, 0.264). No significant effects were identified for age. Although model results were similar for women and men, the strength of the associations between personal wellbeing and depression (z = -2.16, p = 0.015), and depression and SBQ-R suicide risk (z = 1.961, p = 0.025), were stronger in women than in men. Qualitative analysis of an open response question from the CIS suggested that the pandemic had both positive and negative impacts on participants. The COVID-19 pandemic has had a large impact on the mental health and wellbeing of the world's population, particularly vulnerable populations such as autistic people. It is not known if these impacts on mental health and wellbeing have increased suicide risk. Our findings suggest that the impact of the COVID-19 pandemic may be associated with poorer wellbeing and higher depression, but is not associated with suicide risk. Overall, autistic people reported both positive and negative impacts of the pandemic on their lives.
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Qualitative findings showed that many participants believed WFH improved their productivity and mental health.
“and improved their productivity and mental health [45].”
From Homeworking experiences of neuro-divergent workers: systematic review (2024) · cites this paper as [45]
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Pediatric emergency department utilization during the COVID-19 pandemic in New York City
Sokoloff, W. C., Krief, W. I., Giusto, K. A., Mohaimin, T., Murphy-Hockett, C., Rocker, J. A., & Williamson, K. A. (2021) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2021.02.029 · Cited by 75 · cited 3× · see citing works
“There is some evidence that the pandemic has brought upon an increase in suicidal thoughts (O’Connor et al., 2021; Sokoloff et al., 2021), which are strong predictors of suicide attempt (Klonsky et al., 2017; Mars et al., 2019; Nock et al., 2009; Nock et al., 2013).”
BackgroundRisk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
Jokiranta‐Olkoniemi, E., Gyllenberg, D., Sucksdorff, D., Suominen, A., Kronström, K., Chudal, R., & Sourander, A. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04768-x · Cited by 73 · see citing works
Early Pandemic Experiences of Autistic Adults: Predictors of Psychological Distress
Bal, V. H., Wilkinson, E. H., White, L. C., Law, J. K., Feliciano, P., & Chung, W. K. (2021) · Autism Research · doi:10.1002/aur.2480 · Cited by 64 · cited 4× · see citing works
“Based on the literature from both general and autistic populations, summarized above (e.g., Bal et al., 2021; Hedley et al., 2019; Hedley, Uljarevi c, Foley, et al., 2018; O’Connor et al., 2021; Teismann, Forkmann, et al., 2018), we hypothesized that: (a) wellbeing would be a protective factor and…”
BackgroundInfluentialWhat has been the effect of covid-19 on suicide rates?
Appleby, L. (2021) · BMJ · doi:10.1136/bmj.n834 · Cited by 60 · cited 1× · see citing works
“This finding may be due to data being collected during the early stages of the pandemic, thereby concealing longer-term effects (Appleby, 2021; Pirkis et al., 2021).”
BackgroundCohort profile: the Australian Longitudinal Study of Adults with Autism (ALSAA)
Arnold, S. R. C., Foley, K., Hwang, Y. I., Richdale, A. L., Uljarević, M., Lawson, L. P., Cai, R. Y., Falkmer, T., Falkmer, M., Lennox, N., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-030798 · Cited by 58 · cited 3× · see citing works
“Although similar in age and gender distribution to the longitudinal sample (Arnold et al., 2019), the study sample is not reflective of the male-to-female ratio of autism, which is about 3:1 (Loomes et al., 2017).”
BackgroundTeismann, T., Brailovskaia, J., Siegmann, P., Nyhuis, P. W., Wolter, M., & Willutzki, U. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.11.085 · Cited by 52 · see citing works
Considerations for assessing the impact of the COVID-19 pandemic on mental health in Australia
Tan, E. J., Meyer, D., Neill, E., Phillipou, A., Toh, W. L., Rheenen, T. E. V., & Rossell, S. L. (2020) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867420947815 · Cited by 48 · cited 2× · see citing works
“Among the most vulnerable to these impacts are those with pre-existing mental health conditions (Newby et al., 2020; O’Connor et al., 2021; Tan et al., 2020) and disability (Kavanagh et al., 2021).”
BackgroundThe Coronavirus Impact Scale: Construction, Validation, and Comparisons in Diverse Clinical SamplesPreprint
Stoddard, J., Reynolds, E. K., Paris, R., et al. (2021) · doi:10.31234/osf.io/kz4pg · Cited by 43 · see citing works
Hedley, D., Uljarević, M., Cai, R. Y., Bury, S. M., Stokes, M. A., & Evans, D. W. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245562 · Cited by 40 · see citing works
Byrne, S. J., Bailey, E., Lamblin, M., McKay, S., Pirkis, J., Mihalopoulos, C., Spittal, M. J., Rice, S., Hetrick, S., Hamilton, M., et al. (2022) · Trials · doi:10.1186/s13063-022-06072-8 · Cited by 26 · see citing works
Self-citationAutism-related traits and suicide risk among active duty U.S. military service members.
Stanley, I. H., Day, T. N., Gallyer, A. J., Shelef, L., Kalla, C., Gutierrez, P. M., & Joiner, T. E. (2020) · Psychological Services · doi:10.1037/ser0000418 · Cited by 22 · cited 1× · see citing works
“There is emerging evidence that autistic traits or phenotype contribute to heightened suicide risk (Cassidy et al., 2018; Hedley et al., 2021; Stanley et al., 2021).”
BackgroundByrne, S. J., Bailey, E., Lamblin, M., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-518233/v1 · Cited by 6 · see citing works
Haschek, A., Richdale, A. L., Lawson, L. P., Abdullahi, I., Flower, R. L., Unwin, K. L., Hedley, D., & Bury, S. M. (2021) · Figshare · doi:10.26181/5f890479948c5 · Cited by 1 · see citing works
Anxiety and Depression from Adolescence to Old Age in Autism Spectrum Disorder
Uljarević, M., Hedley, D., Cai, R., Hardan, A., & South, M. (2020) · Encyclopedia of Autism Spectrum Disorders · doi:10.1007/978-1-4614-6435-8_102432-1 · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- International Wellbeing Group. (2013). Personal wellbeing index (5th ed.). Deakin University. https://www.acqol.com.au/instruments#measures
- Thorpe, K. G. (2018). The subjective wellbeing of Australians with an Autism Spectrum condition [Master's dissertation, Deakin University, Melbourne, Australia. http://hdl.handle.net/10536/DRO/DU:30112386
Cited by
Sorted by citations
Updated Systematic Review of Suicide in Autism: 2018–2024
Brown, C. M., Newell, V., Sahin, E., & Hedley, D. (2024) · Current Developmental Disorders Reports · doi:10.1007/s40474-024-00308-9 · Cited by 130 · see citing works
“Mood disorders, particularly depression and anxiety, were associated with increased STB risk across multiple studies [57, 74, 75].”
Suicide and COVID-19: a rapid scoping review
Barlattani, T., D’Amelio, C., Capelli, F., Mantenuto, S., Rossi, R., Socci, V., Stratta, P., Stefano, R. D., Rossi, A., & Pacitti, F. (2023) · Annals of General Psychiatry · doi:10.1186/s12991-023-00441-6 · Cited by 54 · see citing works
Mournet, A. M., Wilkinson, E. H., Bal, V. H., & Kleiman, E. M. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102235 · Cited by 49 · see citing works
Santomauro, D. F., Hedley, D., Sahin, E., Brugha, T. S., Naghavi, M., Vos, T., Whiteford, H. A., Ferrari, A. J., & Stokes, M. A. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.116150 · Cited by 41 · see citing works
“Prior work with autistic persons also found no evidence of an association between reported pandemic impact and suicidal ideation (Hedley et al., 2021), suggesting the risk profile for autistic persons may not have been significantly impacted by the COVID-19 pandemic.”
BackgroundNajeeb, P., & Quadt, L. (2024) · Neurodiversity · doi:10.1177/27546330241233088 · Cited by 40 · see citing works
“Furthermore, some studies ( N = 3) (Asbury & Toseeb, 2023; Hedley et al., 2021; Ozsivadjian et al., 2022) focused on the impact of the COVID-19 pandemic and found that some pandemic-asso-ciated adaptations increased autistic individuals ’ well-being.”
InfluentialFridell, A., Norrman, H. N., Girke, L., & Bölte, S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031268 · Cited by 31 · see citing works
Autistic patients' experiences of the hospital setting: A scoping review
Greenwood, E., Cooklin, A., Barbaro, J., & Miller, C. (2023) · Journal of Advanced Nursing · doi:10.1111/jan.15880 · Cited by 30 · see citing works
Hedley, D., Batterham, P. J., Bury, S. M., Clapperton, A., Denney, K. E., Dissanayake, C., Fox, P., Frazier, T. W., Gallagher, E., Hayward, S. M., et al. (2022) · Autism · doi:10.1177/13623613221131234 · Cited by 28 · see citing works
“…of suicidal thoughts, aligned with rumination and repetitive thinking, as well as suicide risk in autistic and non-autistic populations (Hedley et al., 2021b; Kerkhof & van Spijker, 2011; Morrison & O’Connor, 2008), (b) closeness to attempt, which can be indicative of the emergence of…”
BackgroundMethodResultCoping‐resilience profiles and experiences of stress in autistic adults
Muniandy, M., Richdale, A. L., & Lawson, L. P. (2022) · Autism Research · doi:10.1002/aur.2817 · Cited by 17 · see citing works
“While there is emerging evidence to suggest its deleterious effects on stress and well-being in autistic individuals (e.g., Ameis et al., 2020; Corbett et al., 2021), the impact of the pandemic will inevitably vary between individuals (Hedley et al., 2021).”
BackgroundRealpe, A. X., Mills, N., Beasant, L., Douglas, S., Kenny, L., & Rai, D. (2023) · Autism in Adulthood · doi:10.1089/aut.2022.0027 · Cited by 13 · see citing works
Wolff, B., Franco, V. R., Magiati, I., Pestell, C., & Glasson, E. J. (2023) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2023.104566 · Cited by 15 · see citing works
Soto, E. F., Orantes, D., Russo, N. N., & Antshel, K. M. (2024) · Autism · doi:10.1177/13623613241236228 · Cited by 14 · see citing works
“The SBQ-R has been used to assess suicidal behaviors in autistic adult populations (Cassidy et al., 2021; Hedley et al., 2021) and SGM populations (Chu et al., 2019).”
MethodFeatherstone, C., Sharpe, R. A., Axford, N., Asthana, S., Ball, S., & Husk, K. (2022) · Primary Health Care Research & Development · doi:10.1017/s1463423622000755 · Cited by 15 · see citing works
“Emerging research with this population has found that lockdown had a negative effect on mental well-being for autistic adults, including increasing anxiety and stress (Bal et al. , 2021; Pais and Knapp, 2021; Hedley et al. , 2021; Bundy et al. , 2022).”
BackgroundLew‐Koralewicz, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19159468 · Cited by 12 · see citing works
Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders
Shakeshaft, A., Blakey, R., Kwong, A. S. F., Riglin, L., Smith, G. D., Stergiakouli, E., Tilling, K. M., & Thapar, A. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.01.029 · Cited by 12 · see citing works
“Additionally, some autistic individuals reported that the relief of day-to-day social demands was appreciated during the early lockdown (Hedley et al., 2021), with less demands to camouflage or mask behavior (Bundy et al., 2022).”
Friedman, S., Noble, R., Archer, S., Gibson, J. L., & Hughes, C. H. (2023) · Autism · doi:10.1177/13623613231166462 · Cited by 11 · see citing works
“Despite these silver linings, for many, increased social isolation (Hedley et al., 2021; Pellicano et al., 2021) and disruptions to routine (Bundy et al., 2022; Davidson et al., 2021) were linked to poorer well-being.”
BackgroundBal, V., Mournet, A. M., Glascock, T., Shinall, J., Gunin, G., Jadav, N., Zhang, H., Brennan, E., Istvan, E., & Kleiman, E. M. (2023) · Autism · doi:10.1177/13623613231186035 · Cited by 10 · see citing works
“Reports highlighting the impact of the pandemic on mental health and well-being of autistic adults (Adams et al., 2021; Bal et al., 2021; Hedley et al., 2021) underscore the need for brief, problem-focused interventions to support autistic adults through periods of uncertainty and constant change.”
BackgroundHedley, D., Williams, Z. J., Deady, M., Batterham, P. J., Bury, S. M., Brown, C. M., Robinson, J., Trollor, J. N., Uljarević, M., & Stokes, M. A. (2024) · Autism · doi:10.1177/13623613241289493 · Cited by 10 · see citing works
“Clinician determined suicide risk level was based on the study risk protocol (see Hedley, Batterham, et al., 2023; Hedley et al., 2021) and involved discussion with a registered psychologist on the team (authors S.M.”
InfluentialHomeworking experiences of neuro-divergent workers: systematic review
Brooks, S. K., Hall, C. E., Rogers, M. B., & Greenberg, N. (2024) · Occupational Medicine · doi:10.1093/occmed/kqae095 · Cited by 9 · see citing works
The relationship between alexithymia and self-esteem in autistic adolescents
Strang, M., Macmillan, C. M., Brown, C. M., Hooley, M., & Stokes, M. A. (2024) · Research in Autism · doi:10.1016/j.rasd.2024.102334 · Cited by 11 · see citing works
Jeyagurunathan, A., Koh, Y. S., Sambasivam, R., Abdin, E., Samari, E., Chow, W. L., Ma, S., Chong, S. A., & Subramaniam, M. (2025) · Journal of Happiness Studies · doi:10.1007/s10902-025-00889-1 · Cited by 4 · see citing works
“Studies have shown a significant association of the pandemic with poor PWI and high depressive and anxiety symptoms (Hedley et al., 2021; Salari et al., 2020).”
Guo, C., Wong, K. F., Xu, Y., Hung, K. K. C., & Ho, H. C. (2024) · Applied Research in Quality of Life · doi:10.1007/s11482-024-10395-w · Cited by 4 · see citing works
“For instance, the lockdown associated with pandemics such as COVID-19 is believed to cause a wellbeing crisis, with detrimental effects on an individual’s physical and mental wellbeing, especially for vulnerable populations (Dinsuhaimi et al., 2022; Hedley et al., 2021; Owens et al., 2022).”
Kassee, C., Jachyra, P., Mahalingam, V., Tint, A., Lin, H., Ameis, S. H., Martino, A. D., Lunsky, Y., & Lai, M. (2024) · Journal of Applied Research in Intellectual Disabilities · doi:10.1111/jar.13300 · Cited by 3 · see citing works
Saavedra, C. S. F., Sáez, C. P. G., Guillén, V., Andana, M. V., Cid, C. O. L., Collin, S. H., & Riquelme, V. A. R. (2023) · Revista Chilena de Fonoaudiología · doi:10.5354/0719-4692.2023.69295 · Cited by 2 · see citing works
Predictors of Change in Wellbeing and Mental Health of Parents of Autistic Pre-Schoolers
Green, C. C., Smith, J., Bent, C. A., Chetcuti, L., Uljarević, M., Benson, P. R., & Hudry, K. (2024) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06471-7 · Cited by 2 · see citing works
“Some data collection occurred following onset of the COVID-19 world-wide pandemic, during which the local region experienced multiple, protracted periods of lockdown (i.e., stay-at-home order) which have been have been linked to poorer wellbeing and increased depression (Hedley et al., 2021).”
Lowe, J., Jones, S. C., & Mizzi, S. (2024) · Disability & Society · doi:10.1080/09687599.2024.2439973 · Cited by 2 · see citing works
“Although both autistic women and men reported experiencing greater difficulties during the COVID-19 pandemic, the associations between personal wellbeing, depression and suicide risk were stronger among autistic women (Hedley et al. 2021).”
Redquest, B. K., Andreasen, S., Turner, K., & McMorris, C. A. (2023) · Developments in neuroethics and bioethics · doi:10.1016/bs.dnb.2023.05.007 · Cited by 2 · see citing works
Grieve, C. M., Roest, A. M., White, S. W., Ganzevoort, C. O. W., Smit, R. W. H., Bekius, J., van Balkom, I. D. C., & Greaves‐Lord, K. (2026) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-026-00580-y · Cited by 1 · see citing works
Jodra, M., & García-Villamisar, D. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-55049-x · Cited by 1 · see citing works
“This coincides with previous results of several studies 7,8 that proved the existence of this relationship.”
ResultCullen, J. A., Leslie, A., & Haney, J. L. (2024) · Social Work in Mental Health · doi:10.1080/15332985.2024.2357704 · Cited by 1 · see citing works
“Our findings support research indicating that were both positive and negative impacts of COVID-19 on the autistic community (Hedley et al., 2021; Oomen et al., 2021).”
Hedley, D., Williams, Z. J., Deady, M., Batterham, P. J., Bury, S. M., Brown, C. M., Robinson, J., Trollor, J. N., Uljarević, M., & Stokes, M. A. (2024) · doi:10.31219/osf.io/xqd9b · Cited by 1 · see citing works
New Perspectives about the COVID-19 Pandemic for Autistics
Bennett, M., & Goodall, E. (2022) · Emerald Group Publishing Limited eBooks · doi:10.1108/978-1-80455-033-520221004
Spanyol, S., Leung, C., Bennett‐Weston, A., & Silva, A. C. S. E. (2025) · Research in Autism · doi:10.1016/j.reia.2025.202534
In Times of Need: Psychiatric Emergency Department Presentations in Autistic Adults
Courchesne, V., Frayne, M., Castelino, C., Luk, V., Man, L. L. Y., Lee, C.-H. J., Baharikhoob, P., Pace-Tonna, C., Jachyra, P., Ameis, S. H., et al. (2026) · Autism in Adulthood · doi:10.1177/25739581251415125
Double Disadvantage? Wellbeing Among Vietnamese Migrant Parents of Autistic Children
Nguyen, K. P., Pecora, L. A., Hooley, M., & Stokes, M. A. (2026) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-026-07453-7
Neurodiversidade na administração pública brasileira: experiências vividas por servidores públicos
Motta, A. C. D. G. D., da Motta, D. L., & Bouzada, M. A. C. (2026) · Cadernos EBAPE BR · doi:10.1590/1679-395120260009x
Neurodiversity in Brazilian public administration: lived experiences of civil servants
Motta, A. C. D. G. D., da Motta, D. L., & Bouzada, M. A. C. (2026) · Cadernos EBAPE BR · doi:10.1590/1679-395120260009
- Authors
- Hedley, D., Hayward, S. M., Denney, K., Uljarević, M., Bury, S., Sahin, E., Brown, C. M., Clapperton, A., Dissanayake, C., Robinson, J., Trollor, J., & Stokes, M. A.
- Affiliations
- La Trobe University (AU)
- Deakin University (AU)
- The University of Melbourne (AU)
- UNSW Sydney (AU)
- Corresponding author
- Hedley, Darren
- ORCID
- Venue
- Autism Research
- Publisher
- Wiley
- Published
- 2021-09-21
- Volume
- 14
- Issue
- 12
- Pages
- 2663-2676
- ISSN
- 1939-3792 (ISSN-L)
- 1939-3806
- PMC
- PMC8646719
- OpenAlex
- W3200644286
- Cited by
- 38
- References
- 75
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 14 · 2023: 9 · 2022: 7 · 2021: 1
- FWCI
- 5.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Autism Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Own your potential (DEAKIN) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- La Trobe University (cc-by)
- Funders
- Australian Research Council (Discovery Early Career Researcher Award / DE180100)
- National Health and Medical Research Council (Career Development Fellowship / APP1142348)
- Suicide Prevention Australia (National Suicide Prevention Research Fellowship)
- University of Melbourne (Dame Kate Campbell Fellowship)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Keywords
- COVID-19 pandemic, autism spectrum disorder, autistic adults, depression, suicide risk, personal well-being, mental health, gender differences, age differences
- MeSH terms
- Autism Spectrum Disorder, COVID-19, SARS-CoV-2, Adult, Australia, Autistic Disorder, Depression, Female, Humans, Male, Risk Factors, Suicide, Pandemics
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