Cited by 102Hair Growth and Disordersdental development and anomaliesDevelopmental Biology and Gene Regulation

Epidermal patterning and induction of different hair types during mouse embryonic development

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Duverger, Olivier, Morasso, Maria I.·2009·Birth Defects Research Part C: Embryo Today: Reviews

Abstract

An intriguing question in developmental biology is how epidermal pattern formation processes are established and what are the molecular mechanisms involved in these events. The establishment of the pattern is concomitant with the formation of ectodermal appendages, which involves complex interactions between the epithelium and the underlying mesenchyme. Among ectodermal appendages, hair follicles are the “mini organs” that produce hair shafts. Several developmental and structural features are common to all hair follicles and to the hair shaft they produce. However, many different hair types are produced in a single organism. Also, different characteristics can be observed depending on the part of the body where the hair follicle is formed. Here, we review the mechanisms involved in the patterning of different hair types during mouse embryonic development as well as the influence of the body axes on hair patterning. Birth Defects Research (Part C) 87:263–272, 2009. © 2009 Wiley‐Liss, Inc.

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  1. Sundberg JPS 1994 Hair types and subtypes in the laboratory mouse Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biochemical Tools Boca Raton, FL CRC Press

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Authors
Duverger, O., & Morasso, M. I.
Affiliations
National Institutes of Health (US)
Venue
Birth Defects Research Part C: Embryo Today: Reviews
Publisher
Wiley
Published
2009-09
Volume
87
Issue
3
Pages
263-272
ISSN
  • 1542-975X (ISSN-L)
  • 1542-9768
OpenAlex
W2079615431
Cited by
102
References
67
Citations by year
2026: 7 · 2025: 4 · 2024: 11 · 2023: 9 · 2022: 9 · 2021: 4 · 2020: 8 · 2019: 5 · 2018: 7 · 2017: 5 · 2016: 5 · 2015: 3 · 2014: 8 · 2013: 5 · 2012: 8
FWCI
0.64
Type
journal article
Language
en
Open access
Locations
  • Birth Defects Research Part C Embryo Today Reviews (publishedVersion, public-domain)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (ZIAAR041171)
Topics
  • Health Sciences › Medicine › Urology › Hair Growth and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Keywords
epidermal patterning, hair follicle induction, hair shaft, epithelial-mesenchymal interactions, mouse embryo development, body axis, hair follicle development
MeSH terms
Animals, Embryo, Mammalian, Epidermis, Hair, Gene Expression Regulation, Developmental, Body Patterning, Embryonic Development, Mice

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