Deep brain stimulation in the bed nucleus of the stria terminalis and medial forebrain bundle in a patient with major depressive disorder and anorexia nervosa
Open accessAbstract
Deep brain stimulation (DBS) may be considered in severe cases of therapy-refractory major depressive disorder (MDD). However, DBS for MDD is still an experimental therapy. Therefore, it should only be administered in clinical studies driven by multidisciplinary teams, including surgeons with substantial experience of DBS in the treatment of other conditions.
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In a case study, MFB stimulation improved depressive symptoms, but blurred vision could not be reduced by changing stimulation parameters, leading to selection of a new target.
“Although depressive symptoms improved following stimulation, blurred vision could not be attenuated with changes in stimulation parameters and ultimately led to the selection of a new target.”
From Deep brain stimulation for depression. (2022) · cites this paper as [68]
Re-implantation at VC/VS led to remission that was sustained over a 1-year period.
“Re-implantation at the VC/VS led to remission which has been sustained over a 1-year period.”
From Deep brain stimulation for depression. (2022) · cites this paper as [68]
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Hsu, T. I., Nguyen, A., Gendreau, J. L., Brown, N. J., & Oh, M. Y. (2023) · World Neurosurgery · doi:10.1016/j.wneu.2022.12.001 · Cited by 1 · see citing works
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Brain-Machine Interfaces for Closed-Loop Electrical Brain Stimulation in Neuropsychiatric Disorders
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Deep Brain Stimulation in the Management of Neuropsychiatric Conditions in Children
Furlanetti, L. L., Mirza, A. B., Tambirajoo, K., & Ashkan, K. (2022) · Springer eBooks · doi:10.1007/978-3-030-80522-7_42
Neuromodulation Treatment for Anorexia Nervosa: A Brief Review
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Impact of Phase Unwrapping on Multitarget Acoustic Lenses for Transcranial Holography
Attali, D., Tiennot, T., Tanter, M., & Aubry, J. (2025) · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · doi:10.1109/tuffc.2025.3570231
Neurosurgery and Neuromodulation for Eating Disorders
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The bed nucleus of the stria terminalis as a neuromodulatory target for refractory epilepsy
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- Authors
- Blomstedt, P., Naesström, M., & Bodlund, O.
- Affiliations
- Umeå University (SE)
- Corresponding author
- Blomstedt, Patric
- Venue
- Clinical Case Reports
- Publisher
- Wiley
- Published
- 2017-03-31
- Volume
- 5
- Issue
- 5
- Pages
- 679-684
- ISSN
- 2050-0904 (ISSN-L)
- PMC
- PMC5412827
- OpenAlex
- W2605376149
- Cited by
- 77
- References
- 33
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 4 · 2023: 7 · 2022: 10 · 2021: 11 · 2020: 11 · 2019: 9 · 2018: 10 · 2017: 2
- FWCI
- 6.10
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Clinical Case Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- KTH Publication Database DiVA (KTH Royal Institute of Technology) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- deep brain stimulation, bed nucleus of the stria terminalis, medial forebrain bundle, major depressive disorder, anorexia nervosa, treatment-resistant depression, experimental treatment, multidisciplinary team
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