Small Molecule Modulators of K eap1‐ N rf2‐ ARE Pathway as Potential Preventive and Therapeutic Agents

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Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1

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Chronic Inflammation and Oxidative Stress as a Major Cause of Age- Related Diseases and Cancer

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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

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Oxidative Stress and Neurotoxicity

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Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

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Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate

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Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

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Oxidative stress and apoptosis: Impact on cancer therapy

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An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism

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Multitargeted cancer prevention by quercetin

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Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

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Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway

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When NRF2 Talks, Who's Listening?

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Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

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Mechanisms of cadmium carcinogenesis☆

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Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

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Nrf2, a multi‐organ protector?

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Nrf2-Deficient Mice Have an Increased Susceptibility to Dextran Sulfate Sodium–Induced Colitis

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Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

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Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

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BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3

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Dimerization of Substrate Adaptors Can Facilitate Cullin-mediated Ubiquitylation of Proteins by a “Tethering” Mechanism

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Nrf2: friend or foe for chemoprevention?

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Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin

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The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants

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The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

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Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response

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Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

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Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

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Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

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The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

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