Cited by 148Nutritional Studies and DietFatty Acid Research and HealthNutrition and Health Studies

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Dietary intake and depressive symptoms: A systematic review of observational studies

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Murakami, Kentaro, Sasaki, Satoshi·2010·Molecular Nutrition & Food Research

DOI 10.1002/mnfr.200900157

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Abstract

The importance of research into the possible role of dietary intake in depressive symptoms is emphasized by the fact that diet is modifiable. We systematically reviewed observational studies investigating the association between dietary intake and depressive symptoms published in English as of December 2008. Using the PubMed database, 34 publications (23 cross-sectional, 10 prospective cohort, and 1 case-control studies) were identified. The number of subjects (n=80-27,111), age of subjects (15-97 years), dietary assessment method (dietary record, diet history interview, and validated and non-validated dietary questionnaire), depressive symptom assessment (discharge diagnosis, established scale, and self-reported information) varied among studies. Dietary variables most frequently investigated included long chain n-3 PUFA, fish, folate, and other B vitamins. Most studies found no association between dietary variables and depressive symptoms. However, most studies included at least one important methodological limitation, such as no inference for causality, unreliable or rough assessment of diet or depressive symptoms, inadequate treatment of potential confounding factors, and ignorance of the possible mediating or confounding influence of other dietary variables. Further evidence from well-designed observational studies is required to confirm or refute the association between dietary intake and depressive symptoms in free-living settings.

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Authors: Murakami, K., & Sasaki, S.
Affiliations: The University of Tokyo (JP)
Corresponding author: Murakami, Kentaro
ORCID: Murakami, Kentaro
Sasaki, Satoshi
Venue: Molecular Nutrition & Food Research
Publisher: Wiley
Published: 2010-04
Volume: 54
Issue: 4
Pages: 471-488
ISSN: 1613-4125 (ISSN-L)
1613-4133
DOI: 10.1002/mnfr.200900157
OpenAlex: W2063684834
Cited by: 148
References: 43
Citations by year: 2026: 5 · 2025: 4 · 2024: 4 · 2023: 7 · 2022: 7 · 2021: 7 · 2020: 15 · 2019: 12 · 2018: 14 · 2017: 9 · 2016: 10 · 2015: 15 · 2014: 11 · 2013: 9 · 2012: 10
FWCI: 0.81
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Molecular Nutrition & Food Research (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Keywords: dietary intake, depressive symptoms, depression, n-3 long-chain polyunsaturated fatty acids, fish consumption, folic acid, B vitamins, diet and mental health, observational study limitations, confounding
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Animals, Cross-Sectional Studies, Depression, Diet, Female, Fishes, Humans, Male, Middle Aged, Prospective Studies, Vitamin B Complex, Cohort Studies, Fatty Acids, Omega-3, Case-Control Studies

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