Cited by 146Bipolar Disorder and TreatmentMental Health Research TopicsDigital Mental Health Interventions

Behavioral activities collected through smartphones and the association with illness activity in bipolar disorder: Smartphone data in bipolar disorder

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Faurholt-Jepsen, Maria, Vinberg, Maj, Frost, Mads, Debel, Sune, Margrethe Christensen, Ellen, Bardram, Jakob E, Kessing, Lars Vedel·2016·International Journal of Methods in Psychiatric Research

Abstract

Smartphones are useful in symptom-monitoring in bipolar disorder (BD). Objective smartphone data reflecting illness activity could facilitate early treatment and act as outcome in efficacy trials. A total of 29 patients with BD presenting with moderate to severe levels of depressive and manic symptoms used a smartphone-based self-monitoring system during 12 weeks. Objective smartphone data on behavioral activities were collected. Symptoms were clinically assessed every second week using the Hamilton Depression Rating Scale and the Young Mania Rating Scale. Objective smartphone data correlated with symptom severity. The more severe the depressive symptoms (1) the longer the smartphone's screen was "on"/day, (2) more received incoming calls/day, (3) fewer outgoing calls/day were made, (4) less answered incoming calls/day, (5) the patients moved less between cell towers IDs/day. Conversely, the more severe the manic symptoms (1) more outgoing text messages/day sent, (2) the phone calls/day were longer, (3) the fewer number of characters in incoming text messages/day, (4) the lower duration of outgoing calls/day, (5) the patients moved more between cell towers IDs/day. Further, objective smartphone data were able to discriminate between affective states. Objective smartphone data reflect illness severity, discriminates between affective states in BD and may facilitate the cooperation between patient and clinician. Copyright © 2016 John Wiley & Sons, Ltd.

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Registry

Crossref · 10.1002/mpr.1502

Cites

38 of 38 references verified0 citation errors · 0 not checkable

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  • Severe depressive symptoms are associated with shorter duration of incoming and outgoing calls, and fewer incoming and outgoing phone calls and daily text messages.

    “recent work shows that severe depressive symptoms are associated with shorter duration of incoming and outgoing calls, and fewer incoming and outgoing phone calls and daily text messages (13–18).”
  • Prior investigations have primarily focused on detecting presence or absence of depression rather than on assessing its severity, and they have shown overall low accuracy.

    “This has resulted in possible reliability problems, since these investigations have primarily focused on detecting presence or absence of depression rather than on assessing its severity, and they have shown overall low accuracy (14–18, 23–27).”
  • Studies conducted with patients with depression have mostly relied on self-report questionnaires to assign diagnoses and/or measure variation in symptoms and train the models.

    “Those studies conducted with patients with depression have mostly relied on self-report questionnaires to assign diagnoses and/or measure variation in symptoms and train the models.”

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Authors
Faurholt-Jepsen, M., Vinberg, M., Frost, M., Debel, S., Margrethe Christensen, E., Bardram, J. E., & Kessing, L. V.
Affiliations
  • Psychiatric Center Copenhagen; Rigshospitalet; Copenhagen Denmark
  • Rigshospitalet (DK)
  • IT University of Copenhagen (DK)
  • Technical University of Denmark (DK)
Venue
International Journal of Methods in Psychiatric Research
Publisher
Wiley
Published
2016-04-01
Volume
25
Issue
4
Pages
309-323
ISSN
1049-8931 (ISSN-L)
OpenAlex
W2312558038
Cited by
146
References
38
Citations by year
2026: 10 · 2025: 7 · 2024: 12 · 2023: 16 · 2022: 10 · 2021: 15 · 2020: 18 · 2019: 32 · 2018: 16 · 2017: 8 · 2016: 1
FWCI
16.88
Type
journal article
Language
en
Open access
Locations
  • International Journal of Methods in Psychiatric Research (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
  • IT University Of Copenhagen (IT University of Copenhagen) (submittedVersion)
  • Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion)
Funders
European Commission
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
bipolar disorder, smartphone data, depressive symptoms, manic symptoms, mobile phone usage patterns, text messaging, self-monitoring, symptom severity
MeSH terms
Smartphone, Adult, Bipolar Disorder, Female, Humans, Male, Monitoring, Ambulatory, Illness Behavior, Young Adult

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