An examination of the constancy of the rate of molecular evolution

Evolutionary trees from DNA sequences: A maximum likelihood approach.

Felsenstein, J. (1981) · Journal of Molecular Evolution · doi:10.1007/bf01734359 · Cited by 14,571

Estimating absolute rates of molecular evolution and divergence times: A penalized likelihood approach.

Sanderson, M. J. (2002) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a003974 · Cited by 1,977

Statistical tests of selective neutrality in the age of genomics

Nielsen, R. (2001) · Heredity · doi:10.1046/j.1365-2540.2001.00895.x · Cited by 1,908

Estimating the rate of evolution of the rate of molecular evolution

Thorne, J. L., Kishino, H., & Painter, I. S. (1998) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025892 · Cited by 1,317

A nonparametric approach to estimating divergence times in the absence of rate constancy.

Sanderson, M. J. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025731 · Cited by 1,156

The Nearly Neutral Theory of Molecular Evolution

Ohta, T. (1992) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.23.110192.001403 · Cited by 1,149

Phylogeny Estimation and Hypothesis Testing Using Maximum Likelihood

Huelsenbeck, J. P., & Crandall, K. A. (1997) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.28.1.437 · Cited by 1,018

SIMMAP: Stochastic character mapping of discrete traits on phylogenies

Bollback, J. P. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-88 · Cited by 940

Statistical tests of models of DNA substitution

Goldman, N. (1993) · Journal of Molecular Evolution · doi:10.1007/bf00166252 · Cited by 736

Revisiting a Key Innovation in Evolutionary Biology: Felsenstein’s “Phylogenies and the Comparative Method”

Huey, R. B., Garland, T., & Turelli, M. (2019) · The American Naturalist · doi:10.1086/703055 · Cited by 592

Determining Divergence Times of the Major Kingdoms of Living Organisms with a Protein Clock

Doolittle, R. F., Feng, D.-F., Tsang, S., Cho, G., & Little, E. (1996) · Science · doi:10.1126/science.271.5248.470 · Cited by 581

Taxon sampling and the accuracy of phylogenetic analyses

(2008) · Journal of Systematics and Evolution · doi:10.3724/sp.j.1002.2008.08016 · Cited by 553

Forces shaping the fastest evolving regions in the human genome

Pollard, K. S., Salama, S. R., King, B., Kern, A. D., Dreszer, T., Katzman, S., Siepel, A., Pedersen, J. S., Bejerano, G., Baertsch, R., et al. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020168 · Cited by 511

Phylogeny, adaptive radiation, and historical biogeography in Bromeliaceae: Insights from an eight‐locus plastid phylogeny

Givnish, T. J., Barfuss, M. H. J., Van Ee, B., Riina, R., Schulte, K., Horres, R., Gonsiska, P. A., Jabaily, R. S., Crayn, D. M., Smith, J. A. C., et al. (2011) · American Journal of Botany · doi:10.3732/ajb.1000059 · Cited by 507

MOLECULAR EVOLUTION OVER THE MUTATIONAL LANDSCAPE

Gillespie, J. H. (1984) · Evolution · doi:10.1111/j.1558-5646.1984.tb00380.x · Cited by 502

Historical climate change and speciation: neotropical seasonally dry forest plants show patterns of both Tertiary and Quaternary diversification

Pennington, R. T., Lavin, M., Prado, D. E., Pendry, C. A., Pell, S. K., & Butterworth, C. A. (2004) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2003.1435 · Cited by 493

An evaluation of the molecular clock hypothesis using mammalian DNA sequences

Li, W.-H., Tanimura, M., & Sharp, P. M. (1987) · Journal of Molecular Evolution · doi:10.1007/bf02603118 · Cited by 450

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy

Lukeš, J., Mauricio, I. L., Schönian, G., Dujardin, J.-C., Soteriadou, K., Dedet, J.-P., Kuhls, K., Tintaya, K. W. Q., Jirků, M., Chocholová, E., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703678104 · Cited by 444

Correlation of the kinetics of electron transfer activity of various eukaryotic cytochromes c with binding to mitochondrial cytochrome c oxidase.

Ferguson-Miller, S., Brautigan, D. L., & Margoliash, E. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33807-3 · Cited by 443

Angiosperm diversification through time

Magallón, S., & Castillo, A. (2009) · American Journal of Botany · doi:10.3732/ajb.0800060 · Cited by 439

Fast Dating Using Least-Squares Criteria and Algorithms

To, T.-H., Jung, M., Lycett, S., & Gascuel, O. (2016) · Systematic Biology · doi:10.1093/sysbio/syv068 · Cited by 437

Rocks and clocks: calibrating the Tree of Life using fossils and molecules

Donoghue, P. C. J., & Benton, M. J. (2007) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2007.05.005 · Cited by 413

Molecular evolution inDrosophila and the higher diptera: II. A time scale for fly evolution

Beverley, S. M., & Wilson, A. C. (1984) · Journal of Molecular Evolution · doi:10.1007/bf02100622 · Cited by 386

The molecular clock runs more slowly in man than in apes and monkeys

Li, W.-H., & Tanimura, M. (1987) · Nature · doi:10.1038/326093a0 · Cited by 375

Bayesian molecular clock dating of species divergences in the genomics era

dos Reis, M., Donoghue, P. C. J., & Yang, Z. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2015.8 · Cited by 339

Molecular‐clock methods for estimating evolutionary rates and timescales

Ho, S. Y. W., & Duchêne, S. (2014) · Molecular Ecology · doi:10.1111/mec.12953 · Cited by 358

Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea

Zhu, Q., Mai, U., Pfeiffer, W., Janssen, S., Asnicar, F., Sanders, J. G., Belda-Ferre, P., Al-Ghalith, G. A., Kopylova, E., McDonald, D., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13443-4 · Cited by 355

TESTING THE CONSTANT-RATE NEUTRAL ALLELE MODEL WITH PROTEIN SEQUENCE DATA

Hudson, R. R. (1983) · Evolution · doi:10.1111/j.1558-5646.1983.tb05528.x · Cited by 342

Darwinian evolution in the genealogy of haemoglobin

Goodman, M., Moore, G. W., & Matsuda, G. (1975) · Nature · doi:10.1038/253603a0 · Cited by 311

MOLECULAR EVIDENCE FOR NATURAL SELECTION

Kreitman, M., & Akashi, H. (1995) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.26.110195.002155 · Cited by 286

The origin and diversification of eukaryotes: problems with molecular phylogenetics and molecular clock estimation

Roger, A. J., & Hug, L. A. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1845 · Cited by 180

Very slightly deleterious mutations and the molecular clock

Ohta, T. (1987) · Journal of Molecular Evolution · doi:10.1007/bf02111276 · Cited by 101

Estimating Divergence Times in the Presence of an Overdispersed Molecular Clock

Cutler, D. J. (2000) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026264 · Cited by 86

Timing the Origins of Multicellular Eukaryotes Through Phylogenomics and Relaxed Molecular Clock Analyses

Sharpe*, S. C., Eme*, L., Brown, M. W., & Roger, A. J. (2015) · Advances in Marine Genomics · doi:10.1007/978-94-017-9642-2_1 · Cited by 49

Molecular dates for the “cambrian explosion”: The influence of prior assumptions.

Welch, J. J., Fontanillas, E., & Bromham, L. (2005) · Systematic Biology · doi:10.1080/10635150590947212 · Cited by 53

Lack of Self-Averaging in Neutral Evolution of Proteins

Bastolla, U., Porto, M., Roman, H. E., & Vendruscolo, M. (2002) · Physical Review Letters · doi:10.1103/physrevlett.89.208101 · Cited by 35