Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

Séguéla, P., Wadiche, J. I., Dineley‐Miller, K., Dani, J., & Jw, P. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00596.1993 · Cited by 1,471 · see citing works

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

Freedman, R., Hall, M., Adler, L. E., & Leonard, S. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00252-x · Cited by 678 · see citing works

Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex

Granon, S., Passetti, F., Thomas, K. L., Dalley, J. W., Everitt, B. J., & Robbins, T. W. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-03-01208.2000 · Cited by 546 · see citing works

The Cerebral Cortex of the Rat and Visual Attentional Function: Dissociable Effects of Mediofrontal, Cingulate, Anterior Dorsolateral, and Parietal Cortex Lesions on a Five-Choice Serial Reaction Time Task

Muir, J. L., Everitt, B. J., & Robbins, T. W. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.3.470 · Cited by 503 · see citing works

Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

Orr‐Urtreger, A., Göldner, F. M., Saeki, M., Lorenzo, I., Goldberg, L. B., Biasi, M. D., Dani, J. A., Patrick, J. W., & Beaudet, A. L. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09165.1997 · Cited by 494 · see citing works

Glutamate, Dopamine, and Schizophrenia: From Pathophysiology to Treatment

LARUELLE, M., KEGELES, L. S., & ABI‐DARGHAM, A. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.063 · Cited by 437 · see citing works

Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia

Martin, L., Kem, W., & Freedman, R. (2004) · Psychopharmacology · doi:10.1007/s00213-003-1750-1 · Cited by 340 · see citing works

α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of <i>Acra7</i>-Deficient Mice

Paylor, R., Nguyen, M., Crawley, J. N., Patrick, J., Beaudet, A., & Orr-Urtreger, A. (1998) · Learning &amp; Memory · doi:10.1101/lm.5.4.302 · Cited by 298 · see citing works

Selective α 7 -nicotinic agonists normalize inhibition of auditory response in DBA mice

Stevens, K. E., Kem, W. R., Mahnir, V. M., & Freedman, R. (1998) · Psychopharmacology · doi:10.1007/s002130050573 · Cited by 269 · see citing works

Animal models of attention-deficit hyperactivity disorder.

Davids, E., Zhang, K., Tarazi, F. I., & Baldessarini, R. J. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00274-6 · Cited by 250 · see citing works

Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task

Grottick, A. J., & Higgins, G. A. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00305-3 · Cited by 240 · see citing works

Safety, Pharmacokinetics, and Effects on Cognitive Function of Multiple Doses of GTS-21 in Healthy, Male Volunteers

KITAGAWA, H., TAKENOUCHI, T., Azuma, R., Wesnes, K. A., Kramer, W. G., Clody, D. E., & Burnett, A. L. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300028 · Cited by 238 · see citing works

Nicotine Improves Sustained Attention in Mice: Evidence for Involvement of the α7 Nicotinic Acetylcholine Receptor

Young, J. W., Finlayson, K., Spratt, C., Marston, H. M., Crawford, N., Kelly, J. S., & Sharkey, J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300393 · Cited by 219 · see citing works

Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task

Puumala, T., & Sirviö, J. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00392-8 · Cited by 201 · see citing works

Nicotinic α7 receptors: Synaptic options and downstream signaling in neurons

Berg, D. K., & Conroy, W. G. (2002) · Journal of Neurobiology · doi:10.1002/neu.10116 · Cited by 198 · see citing works

Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo.

Briggs, C., Anderson, D. J., Brioni, J., Buccafusco, J., Buckley, M., Campbell, J. E., Decker, M. W., Donnelly-Roberts, D., Elliott, R., Gopalakrishnan, M., et al. (1997) · Pharmacology, Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00354-1 · Cited by 190 · see citing works

Nicotine-induced enhancement of attention in the five-choice serial reaction time task: the influence of task demands

Hahn, B., Shoaib, M., & Stolerman, I. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1005-6 · Cited by 188 · see citing works

Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype

Humby, T., Laird, F. M., Davies, W., & Wilkinson, L. S. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00701.x · Cited by 180 · see citing works

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia

Marutle, A., Zhang, X., Court, J., Piggott, M., Johnson, M., Perry, R., Perry, E., & Nordberg, A. (2001) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(01)00117-x · Cited by 175 · see citing works

Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies

Blondel, A., Sanger, D. J., & Moser, P. C. (2000) · Psychopharmacology · doi:10.1007/s002130000378 · Cited by 138 · see citing works

Attentional effects of nicotinic agonists in rats

Hahn, B., Sharples, C. G. V., Wonnacott, S., Shoaib, M., & Stolerman, I. P. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00099-6 · Cited by 135 · see citing works

Codistribution of a sensory gating deficit and schizophrenia in multi-affected families

Waldo, M. C., Carey, G., Myles‐Worsley, M., Cawthra, E. M., Adler, L. E., Nagamoto, H. T., Wender, P. H., Byerley, W., Plaetke, R., & Freedman, R. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90092-4 · Cited by 129 · see citing works

Differential effects of psychomotor stimulants on attentional performance in rats: nicotine, amphetamine, caffeine and methylphenidate

Bizarro, L., Patel, S., Murtagh, C., & Stolerman, I. P. (2004) · Behavioural Pharmacology · doi:10.1097/01.fbp.0000131574.61491.50 · Cited by 115 · see citing works

The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics?

Olivier, B., Leahy, C. L., Mullen, T., Paylor, R. E., Groppi, V. E., Sarnyai, Z., & Brunner, D. (2001) · Psychopharmacology · doi:10.1007/s002130100828 · Cited by 114 · see citing works

Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning

Wehner, J. M., Keller, J. J., Keller, A. B., Picciotto, M. R., Paylor, R. E., Booker, T. K., Beaudet, A. L., Heinemann, S., & Balogh, S. A. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.07.016 · Cited by 105 · see citing works

Performance deficit of α7 nicotinic receptor knockout mice in a delayed matching‐to‐place task suggests a mild impairment of working/episodic‐like memory

Fernandes, C., Hoyle, E., Dempster, E. L., Schalkwyk, L. C., & Collier, D. A. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00176.x · Cited by 97 · see citing works

Effects of α4/β2- and α7-nicotine acetylcholine receptor agonists on prepulse inhibition of the acoustic startle response in rats and mice

Schreiber, R., Dalmus, M., & Vry, J. D. (2001) · Psychopharmacology · doi:10.1007/s00213-001-0927-8 · Cited by 84 · see citing works

Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGLU2/3 receptor agonist LY379268

Greco, B., Invernizzi, R. W., & Carli, M. (2005) · Psychopharmacology · doi:10.1007/s00213-004-2127-9 · Cited by 80 · see citing works

Nicotine-induced Attentional Enhancement in Rats Effects of Chronic Exposure to Nicotine

Hahn, B. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00348-2 · Cited by 78 · see citing works

Attentional performance of C57BL/6 and DBA/2 mice in the 5-choice serial reaction time task

Patel, S., Stolerman, I. P., Asherson, P. J., & Sluyter, F. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.02.019 · Cited by 78 · see citing works

Absence of α7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures

Franceschini, D., Paylor, R. E., Broide, R. S., Salas, R., Bassetto, L., Gotti, C., & Biasi, M. D. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(01)00309-6 · Cited by 72 · see citing works

Involvement of the prefrontal cortex but not the dorsal hippocampus in the attention-enhancing effects of nicotine in rats

Hahn, B., Shoaib, M. C., & Stolerman, I. P. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1438-6 · Cited by 70 · see citing works

DMXB, an ?7 nicotinic agonist, normalizes auditory gating in isolation-reared rats

O’Neill, H. C., Rieger, K., Kem, W. R., & Stevens, K. E. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1482-2 · Cited by 57 · see citing works

Null mutant analysis of responses to nicotine: Deletion of β2 nicotinic acetylcholine receptor subunit but not α7 subunit reduces sensitivity to nicotine-induced locomotor depression and hypothermia

Tritto, T., McCallum, S. E., Waddle, S., Hutton, S. R., Paylor, R. E., Collins, A. C., & Marks, M. J. (2004) · Nicotine & Tobacco Research · doi:10.1080/14622200310001656966 · Cited by 57 · see citing works

Performance of α7 nicotinic receptor null mutants is impaired in appetitive learning measured in a signaled nose poke task

Keller, J. J., Keller, A. B., Bowers, B. J., & Wehner, J. M. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.03.004 · Cited by 57 · see citing works

The role of nicotinic receptor α7 subunits in nicotine discrimination

Stolerman, I. P., Chamberlain, S. A. F., Bizarro, L., Fernandes, C., & Schalkwyk, L. C. (2003) · Neuropharmacology · doi:10.1016/j.neuropharm.2003.10.002 · Cited by 56 · see citing works

Nicotinic Agonist Modulation of Neurotransmitter Levels in the Rat Frontoparietal Cortex

Summers, K. L., Kem, W. R., & Giacobini, E. (1997) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.74.139 · Cited by 40 · see citing works

Input dysfunction, schizotypy, and genetic models of schizophrenia

Freedman, R., Adler, L. E., D, A. O. M., Waldo, M. C., Ross, R. G., Stevens, K. E., & Leonard, S. S. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00348-6 · Cited by 31 · see citing works

Tolerance to nicotine in mice lacking α7 nicotinic receptors

Naylor, C. G., Quarta, D., Fernandes, C., & Stolerman, I. P. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2187-5 · Cited by 20 · see citing works

Modes and models of forebrain cholinergic neuromodulation of cognition

Hasselmo, M. E., & Sarter, M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.104 · Cited by 733 · see citing works

The Nicotinic Acetylcholine Receptor  5 Subunit Plays a Key Role in Attention Circuitry and Accuracy

Bailey, C. D. C., De Biasi, M., Fletcher, P. J., & Lambe, E. K. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2258-10.2010 · Cited by 146 · see citing works

Prefrontal β2 Subunit-Containing and α7 Nicotinic Acetylcholine Receptors Differentially Control Glutamatergic and Cholinergic Signaling

Parikh, V., Ji, J., Decker, M. W., & Sarter, M. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5712-09.2010 · Cited by 133 · see citing works

α7 and non‐α7 nicotinic acetylcholine receptors modulate dopamine release <i>in vitro</i> and <i>in vivo</i> in the rat prefrontal cortex

Livingstone, P. D., Srinivasan, J., Kew, J. N. C., Dawson, L. A., Gotti, C., Moretti, M., Shoaib, M., & Wonnacott, S. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06613.x · Cited by 133 · see citing works

Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice

Fowler, C. D., Arends, M. A., & Kenny, P. J. (2008) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32830c360e · Cited by 131 · see citing works

Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences

Poorthuis, R. B., Goriounova, N. A., Couey, J. J., & Mansvelder, H. D. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.04.031 · Cited by 102 · see citing works

Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test

Young, J. W., Meves, J. M., & Geyer, M. A. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.11.028 · Cited by 69 · see citing works

Nicotine addiction and psychiatric disorders

Kutlu, M. G., Parikh, V., & Gould, T. J. (2015) · International Review of Neurobiology · doi:10.1016/bs.irn.2015.08.004 · Cited by 65 · see citing works

Role of α7- and β4-Containing Nicotinic Acetylcholine Receptors in the Affective and Somatic Aspects of Nicotine Withdrawal: Studies in Knockout Mice

Stoker, A. K., Olivier, B., & Markou, A. (2012) · Behavior Genetics · doi:10.1007/s10519-011-9511-0 · Cited by 40 · see citing works

Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing

Koukouli, F., Rooy, M., Changeux, J.-P., & Maskos, U. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614417113 · Cited by 33 · see citing works

Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system

Ng, T. H. J., Sarikahya, M. H., Hudson, R., Szkudlarek, H. J., Pérez-Valenzuela, E., Uzuneser, T. C., Proud, E., Gummerson, D., Youssef, M., Machado, M., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01853-y · Cited by 23 · see citing works

Nicotinic α7- or β2-containing receptor knockout: Effects on radial-arm maze learning and long-term nicotine consumption in mice

Levin, E. D., Petro, A. E., Rezvani, A. H., Pollard, N., Christopher, N. C., Strauss, M., Avery, J., Nicholson, J. L., & Rose, J. E. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.08.048 · Cited by 123 · see citing works

Assessment of attentional function and impulsivity using 5-choice serial reaction time task/3-choice serial reaction time task

Ohmura, Y., Tsutsui‐Kimura, I., & Yoshioka, M. (2009) · Folia Pharmacologica Japonica · doi:10.1254/fpj.134.137 · Cited by 3 · see citing works

Sustained attention and serial responding in heat: mental effort in the control of performance.

Razmjou, S., & Kjellberg, A. (1992) · PubMed · Cited by 38 · see citing works

Choice reaction time behavior in humans (Homo sapiens) and rats (Rattus Norvegicus): a comparison in the procedurally matched task

Furuya, I., Kazumi, S., MIYAGI, Y., et al. (2012) · Japanese Journal of Animal Psychology · doi:10.2502/janip.62.1.1

Attentional performance of C57BL/6 and DBA/2 mice in the 5-choice serial reaction time task

Patel, S., Stolerman, I. P., Asherson, P. J., & Sluyter, F. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.02.019 · Cited by 78 · see citing works