Cholesterol-lowering effects of Lactobacillus species
Abstract
Probiotics are the living and non-pathogenic microbial supplements which, upon administration in adequate quantities, influence the host organism positively by improving gut health and enhancing intestinal mucosal integrity. They suppress potentially pathogenic microorganisms by competing with them for nutrients as well as space for gut adherence. Lactobacillus species are the most commonly used bacteria in the probiotic preparations and studies show that they have cholesterol-lowering effects on the hosts. Lipids are biological molecules that are insoluble in water and bile salts play a major role in their digestion as they are synthesized and conjugated to taurine or glycine in the liver. Bile salt hydrolase deconjugates taurine or glycine from bile salts. Cholesterol metabolism is influenced by the effect of Lactobacillus species on microbial populations as well as overall metabolic activity of human intestinal microflora. Deconjugation of bile salt, concentration of short-chain fatty acids and molar proportion of propionate constitute the major processes by which cholesterol lowering is brought about by Lactobacillus species. This review summarizes the cholesterol-lowering properties of this species. A significant number of Lactobacillus strains have been known to display substantial bile salt hydrolase activities and identifying those strains for use in therapeutic purposes can be a great advancement. Here, this identification is done using phylogenetic relationship for different identified potential probiotic Lactobacillus strains.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Bifidobacterium, Pediococcus, and Lactobacillus secrete bile salt hydrolase, which deconjugates primary bile acids and reduces cholesterol reabsorption in the host.
“Species such as Bifidobacterium, Pediococcus, and Lactobacillus secrete this hydrolase, which deconjugates primary bile acids and reduces cholesterol reabsorption in the host’s body [102].”
From Current Concepts in Probiotic Safety and Efficacy (2026) · cites this paper as [102]
Cites
MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets
Kumar, S., Stecher, G., & Tamura, K. (2016) · Molecular Biology and Evolution · doi:10.1093/molbev/msw054 · Cited by 43,923 · see citing works
The rapid generation of mutation data matrices from protein sequences
Jones, D. T., Taylor, W. R., & Thornton, J. M. (1992) · Computer applications in the biosciences · doi:10.1093/bioinformatics/8.3.275 · Cited by 6,916 · see citing works
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
Malfertheiner, P., Mégraud, F., O'Morain, C. A., Gisbert, J. P., Kuipers, E. J., Axon, A. T. R., Bazzoli, F., Gasbarrini, A., Atherton, J. C., Graham, D. Y., et al. (2016) · Gut · doi:10.1136/gutjnl-2016-312288 · Cited by 2,969 · see citing works
Effects of probiotics, prebiotics, and synbiotics on human health
Markowiak, P., & Śliżewska, K. (2017) · Nutrients · doi:10.3390/nu9091021 · Cited by 2,401 · see citing works
Bile Salt Hydrolase Activity in Probiotics
Begley, M., Hill, C., & Gahan, C. G. M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.3.1729-1738.2006 · Cited by 1,187 · see citing works
Probiotics, gut microbiota, and their influence on host health and disease
Sánchez, B., Delgado, S., Blanco‐Míguez, A., Lourenço, A., Gueimonde, M., & Margolles, A. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600240 · Cited by 1,104 · see citing works
Jones, B. V., Begley, M., Hill, C., Gahan, C. G. M., & Marchesi, J. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804437105 · Cited by 1,098 · see citing works
Dunne, C., O’Mahony, L., Murphy, L., Thornton, G., Morrissey, D., O’Halloran, S., Feeney, M., Flynn, S., Fitzgerald, G., Daly, C., et al. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.2.386s · Cited by 922 · see citing works
Adhesion, autoaggregation and hydrophobicity of 13 strains of Bifidobacterium longum
Del Re, B., Sgorbati, B., Miglioli, M., & Palenzona, D. (2000) · Letters in Applied Microbiology · doi:10.1046/j.1365-2672.2000.00845.x · Cited by 731 · see citing works
Cholesterol-Lowering Effects of Probiotics and Prebiotics: A Review of in Vivo and in Vitro Findings
Ooi, L.-G., & Liong, M. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11062499 · Cited by 690 · see citing works
Assimilation of cholesterol by Lactobacillus acidophilus
Gilliland, S. E., Nelson, C. R., & Maxwell, C. V. (1985) · Applied and Environmental Microbiology · doi:10.1128/aem.49.2.377-381.1985 · Cited by 652 · see citing works
Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut
Joyce, S. A., MacSharry, J., Casey, P. G., Kinsella, M., Murphy, E. F., Shanahan, F., Hill, C., & Gahan, C. G. M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1323599111 · Cited by 604 · see citing works
Severe Food Protein-Induced Enterocolitis Syndrome to Cow’s Milk in Infants
Yang, M., Geng, L., Xu, Z., Chen, P., Friesen, C. A., Gong, S., & Li, D. (2015) · Nutrients · doi:10.3390/nu8010001 · Cited by 496 · see citing works
Chen, K., Chen, H., Faas, M. M., de Haan, B. J., Li, J., Xiao, P., Zhang, H., Diana, J., de Vos, P., & Sun, J. T. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201601006 · Cited by 461 · see citing works
Cholesterol-Lowering Probiotics as Potential Biotherapeutics for Metabolic Diseases
Kumar, M., Nagpal, R., Kumar, R., Hemalatha, R., Verma, V., Kumar, A., Chakraborty, C., Singh, B., Marotta, F., Jain, S., et al. (2012) · Experimental Diabetes Research · doi:10.1155/2012/902917 · Cited by 439 · see citing works
The Scientific Basis for Probiotic Strains ofLactobacillus
Reid, G. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.9.3763-3766.1999 · Cited by 399 · see citing works
Cappello, S., Cereda, E., Rondanelli, M., Klersy, C., Cameletti, B., Albertini, R., Magno, D., Caraccia, M., Turri, A., & Caccialanza, R. (2016) · Nutrients · doi:10.3390/nu9010001 · Cited by 394 · see citing works
Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches
Papadimitriou, K., Ζουμποπούλου, Γ., Foligné, B., Alexandraki, V., Κάζου, Μ., Pot, B., & Tsakalidou, E. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00058 · Cited by 388 · see citing works
Studies of a surfactant and cholesteremia in the Maasai
Mann, G. V., & Spoerry, A. (1974) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/27.5.464 · Cited by 386 · see citing works
Nguyen, T. D. T., Kang, J.-H., & Lee, M. S. (2006) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2006.08.015 · Cited by 376 · see citing works
Jones, M. L., Martoni, C., Parent, M., & Prakash, S. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511004703 · Cited by 323 · see citing works
Shehata, M. G., Sohaimy, S. A. E., El-Sahn, M. A., & Youssef, M. (2016) · Annals of Agricultural Science Cairo · doi:10.1016/j.aoas.2016.03.001 · Cited by 307 · see citing works
The Intestinal Microbiota in Metabolic Disease
Woting, A., & Blaut, M. (2016) · Nutrients · doi:10.3390/nu8040202 · Cited by 284 · see citing works
Screening of Lactic Acid Bacteria for Bile Salt Hydrolase Activity
Tanaka, H., Doesburg, K. K., Iwasaki, T., & Mierau, I. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75506-2 · Cited by 283 · see citing works
Gupta, V, & Garg, R. (2009) · Indian Journal of Medical Microbiology · doi:10.4103/0255-0857.53201 · Cited by 283 · see citing works
Saminathan, M., Sieo, C. C., Ramasamy, K., Abdullah, N., & Ho, Y. W. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6365 · Cited by 273 · see citing works
Pereira, D. I. A., McCartney, A. L., & Gibson, G. R. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.8.4743-4752.2003 · Cited by 215 · see citing works
Lambert, J. M., Bongers, R. S., de Vos, W. M., & Kleerebezem, M. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00137-08 · Cited by 212 · see citing works
Ateşçi, Y. Z., Aydoğdu, Ö., Karaköse, A., Pekedis, M., Karal, Ö., Şentürk, U., & Çınar, M. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/462623 · Cited by 194 · see citing works
Bile Salt Hydrolase Activity of Three Strains of Lactobacillus acidophilus
Corzo, G. A., & Gilliland, S. E. (1999) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(99)75256-2 · Cited by 190 · see citing works
Nutraceutical therapies for atherosclerosis
Moss, J. W. E., & Ramji, D. P. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.103 · Cited by 186 · see citing works
Evidence for Hypocholesterolemic Effect of Lactobacillus reuteri in Hypercholesterolemic Mice
Taranto, M. P., Medici, M., Perdigón, G., Holgado, A. P. R., & de Valdez, G. F. (1998) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(98)70123-7 · Cited by 177 · see citing works
Tsai, C., Lin, P.-P., Hsieh, Y.-M., Zhang, Z., Wu, H.-C., & Huang, C.-C. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/690752 · Cited by 149 · see citing works
SPME Method Optimized by Box-Behnken Design for Impact Odorants in Reduced Alcohol Wines
Saha, B., Longo, R., Torley, P. J., Saliba, A. J., & Schmidtke, L. M. (2018) · Foods · doi:10.3390/foods7080127 · Cited by 145 · see citing works
Elkins, C. A., Moser, S. A., & Savage, D. C. (2001) · Microbiology · doi:10.1099/00221287-147-12-3403 · Cited by 142 · see citing works
Lactobacillus Effects on Cholesterol: In Vitro and In Vivo Results
Lin, S. Y., Ayres, J. W., Winkler, W., & Sandine, W. E. (1989) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(89)79439-x · Cited by 131 · see citing works
Madjd, A., Taylor, M. A., Mousavi, N., Delavari, A., Malekzadeh, R., Macdonald, I. A., & Farshchi, H. R. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.120170 · Cited by 118 · see citing works
Lactobacillus Molecular Biology: From Genomics to Probiotics
Ljungh, Å., & Wadström, T. (2009) · Medical Entomology and Zoology · Cited by 111 · see citing works
Askari, G., Bayat, A., Azizi-Soleiman, F., Heidari‐Beni, M., Feizi, A., Iraj, B., & Ghiasvand, R. (2016) · International Journal of Preventive Medicine · doi:10.4103/2008-7802.175455 · Cited by 92 · see citing works
Tribe, D. E., & Gordon, J. G. (1955) · British Journal Of Nutrition · doi:10.1079/bjn19550003 · Cited by 87 · see citing works
The Role of Bacteria, Probiotics and Diet in Irritable Bowel Syndrome
Harper, A. J., Naghibi, M., & Garcha, D. S. (2018) · Foods · doi:10.3390/foods7020013 · Cited by 77 · see citing works
Canova, C., Pitter, G., Ludvigsson, J. F., Romor, P., Zanier, L., Zanotti, R., & Simonato, L. (2016) · BMC Gastroenterology · doi:10.1186/s12876-015-0415-y · Cited by 62 · see citing works
Seddik, H. A., Bendali, F., Cudennec, B., & Drider, D. (2017) · Research in Microbiology · doi:10.1016/j.resmic.2016.12.003 · Cited by 57 · see citing works
Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome
Chumpitazi, B. P., & Shulman, R. J. (2016) · Molecular and Cellular Pediatrics · doi:10.1186/s40348-016-0036-8 · Cited by 52 · see citing works
Lactobacillus plantarum CUL66 can impact cholesterol homeostasis in Caco-2 enterocytes
Michael, D. R., Moss, J. W. E., de la Lama-Calvente, D., Garaiová, I., Plummer, S. F., & Ramji, D. P. (2016) · Beneficial Microbes · doi:10.3920/bm2015.0146 · Cited by 51 · see citing works
Small intestinal bacterial overgrowth as a cause for irritable bowel syndrome: guilty or not guilty?
Aziz, I., Törnblom, H., & Simrén, M. (2017) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000348 · Cited by 45 · see citing works
Noninvasive molecular analysis ofHelicobacter pylori: Is it time for tailored first-line therapy?
Ierardi, E., Giorgio, F., Iannone, A., Losurdo, G., Principi, M., Barone, M., Pisani, A. R., & Leo, A. D. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i14.2453 · Cited by 41 · see citing works
Kobyliak, N. M., Falalyeyeva, T. M., Virchenko, O., Mykhalchyshyn, G., Bodnar, P., NIa, S., Yankovsky, D., Beregova, T. V., & Остапченко, Л. І. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0451-2 · Cited by 40 · see citing works
In vitro and in vivo cholesterol lowering ability of Lactobacillus pentosus KF923750
Bendali, F., Kerdouche, K., Hamma-Faradji, S., & Drider, D. (2017) · Beneficial Microbes · doi:10.3920/bm2016.0121 · Cited by 40 · see citing works
Mohan, J. C., Arora, R., & Khalilullah, M. (1990) · PubMed · Cited by 29 · see citing works
Preventive Health Care among Rural American Indians in New Mexico
Gilliland, F. D., Mahler, R., Hunt, W. C., & Davis, S. M. (1999) · Preventive Medicine · doi:10.1006/pmed.1998.0401 · Cited by 29 · see citing works
Functional food addressing heart health: do we have to target the gut microbiota?
Ryan, P. M., Ross, R. P., Fitzgerald, G. F., Caplice, N. M., & Stanton, C. (2015) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0000000000000224 · Cited by 28 · see citing works
Cardiovascular Risk in Parents of Children With Extreme Lipoprotein Cholesterol Levels
CROFT, J. B., Cresanta, J. L., Webber, L. S., SRINIVASAN, S. R., Freedman, D. S., Burke, G. L., & Berenson, G. S. (1988) · Southern Medical Journal · doi:10.1097/00007611-198803000-00014 · Cited by 10 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Shaping the Future of Probiotics and Prebiotics
Cunningham, M., Azcarate-Peril, M. A., Barnard, A., Benoit, V., Grimaldi, R., Guyonnet, D., Holscher, H. D., Hunter, K., Manurung, S., Obis, D., et al. (2021) · Trends in Microbiology · doi:10.1016/j.tim.2021.01.003 · Cited by 637 · see citing works
Next-generation probiotics: the upcoming biotherapeutics
Al-Fakhrany, O. M., & Elekhnawy, E. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09398-5 · Cited by 201 · see citing works
Health Benefits of Prebiotics, Probiotics, Synbiotics, and Postbiotics
Al-Habsi, N. A., Al‐Khalili, M., Haque, S. A., Elias, M., Olqi, N. A., & Uraimi, T. A. (2024) · Nutrients · doi:10.3390/nu16223955 · Cited by 194 · see citing works
Wang, Y., Han, J., Wang, D., Gao, F., Zhang, K., Tian, J., & Jin, Y. (2022) · Foods · doi:10.3390/foods11142090 · Cited by 143 · see citing works
In vitro bile salt hydrolase (BSH) activity screening of different probiotic microorganisms
Hernández-Gómez, J. G., López-Bonilla, A., Trejo-Tapia, G., Ávila-Reyes, S. V., Jiménez-Aparicio, A. R., & Hernández-Sánchez, H. (2021) · Foods · doi:10.3390/foods10030674 · Cited by 122 · see citing works
Gut Microbiota-Derived Metabolites in Colorectal Cancer: The Bad and the Challenges
Zhang, W., An, Y., Qin, X., Wu, X., Wang, X., Hou, H., Song, X., Liu, T., Wang, B., Huang, X., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.739648 · Cited by 119 · see citing works
Agolino, G., Pino, A., Vaccalluzzo, A., Cristofolini, M., Solieri, L., Caggia, C., & Randazzo, C. L. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106357 · Cited by 87 · see citing works
Stasiak-Różańska, L., Berthold‐Pluta, A., Pluta, A., Dasiewicz, K., & Garbowska, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18031108 · Cited by 76 · see citing works
Huang, S., Lin, L., Wang, S., Ding, W., Zhang, C., Shaukat, A., Xu, B., Yue, K., Zhang, C., & Liu, F. (2023) · Antioxidants · doi:10.3390/antiox12040819 · Cited by 65 · see citing works
Echresh, S., Behbahani, B. A., Falah, F., Noshad, M., & Ibrahim, S. A. (2024) · LWT · doi:10.1016/j.lwt.2024.116391 · Cited by 58 · see citing works
Elmansy, E. A., El-Kady, E. M., Asker, M. S., Abdou, A. M., Abdallah, N. A., & Amer, S. K. (2022) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-022-03439-6 · Cited by 50 · see citing works
Dell’Anno, M., Callegari, M. L., Reggi, S., Caprarulo, V., Giromini, C., Spalletta, A., Coranelli, S., Rossi, C. A. S., & Rossi, L. (2021) · Animals · doi:10.3390/ani11061766 · Cited by 48 · see citing works
Chakravarty, K., Gaur, S., Kumar, R., Jha, N. K., & Gupta, P. K. (2024) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10328-x · Cited by 40 · see citing works
Self-citationŚcieszka, S., & Klewicka, E. (2020) · Foods · doi:10.3390/foods9070959 · Cited by 39 · see citing works
Chai, C., Guo, Y., Mohamed, T. M., Gifty, Z. B., Wang, Y., Zeng, X., Zhao, J., Du, H., Tang, Z., Xu, Y., et al. (2023) · Animals · doi:10.3390/ani13101690 · Cited by 36 · see citing works
Tian, L., Liu, R., Zhou, Z., Xu, X., Feng, S., Kushmaro, A., Marks, R. S., Wang, D., & Sun, Q. (2022) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-021-09886-1 · Cited by 35 · see citing works
Freire, M. O. D. L., Neto, J. P. R. C., Lemos, D. E. D. A., de Albuquerque, T. M. R., Garcia, E. F., de Souza, E. L., & Alves, J. L. D. B. (2024) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10235-1 · Cited by 35 · see citing works
Zhang, X., Shangguan, W., Wang, J., Liao, Z., Fang, X., & Zhong, Q. (2023) · LWT · doi:10.1016/j.lwt.2023.114529 · Cited by 34 · see citing works
Lee, J. Y., Park, J.-Y., Jeong, Y., & Kang, C.-H. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2301.01028 · Cited by 32 · see citing works
Feng, K., Zhang, H., Chen, C., Ho, C., Kang, M., Zhu, S., Xu, J., Deng, X., Huang, Q., & Cao, Y. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c01881 · Cited by 32 · see citing works
Zhang, F., Lo, E. K. K., Chen, J., Wang, K., Felicianna, Ismaiah, M. J., Leung, H. K. M., Zhao, D., Lee, J. C., & El-Nezami, H. S. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c08910 · Cited by 31 · see citing works
Behbahani, B. A., Noshad, M., Namazi, P., & Vasiee, A. (2024) · LWT · doi:10.1016/j.lwt.2024.116850 · Cited by 31 · see citing works
Qiu, X., Wu, Q., Li, W., Tang, K., & Zhang, J. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.06.030 · Cited by 27 · see citing works
Defaix, R., Lokesh, J., Ghislain, M., Béchec, M. L., Marchand, M., Véron, V., Surget, A., Biasutti, S., Terrier, F., Pigot, T., et al. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.740049 · Cited by 27 · see citing works
Breyer, G. M., Arechavaleta, N. N., Siqueira, F. M., & da Motta, A. D. S. (2020) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-020-09700-4 · Cited by 26 · see citing works
Ertürkmen, P., Fırıncıoğulları, B., & Öner, Z. (2023) · Current Microbiology · doi:10.1007/s00284-023-03311-2 · Cited by 25 · see citing works
Current Concepts in Probiotic Safety and Efficacy
Churin, A. A., Sokolyanskaya, L. O., Lukina, A. P., & Karnachuk, O. V. (2026) · Nutrients · doi:10.3390/nu18040696 · Cited by 31 · see citing works
“Species such as Bifidobacterium , Pediococcus , and Lactobacillus secrete this hydrolase, which deconjugates primary bile acids and reduces cholesterol reabsorption in the host’s body [102].”
Tjandrawinata, R. R., Kartawijaya, M., & Hartanti, A. W. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.825251 · Cited by 24 · see citing works
Pakwan, C., Chitov, T., Chantawannakul, P., Manasam, M., Bovonsombut, S., & Disayathanoowat, T. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242560 · Cited by 21 · see citing works
Rajan, W., Diwanay, S. S., Patole, M. S., Sayyed, R. Z., AL-Shwaiman, H. A., Alkhulaifi, M. M., Elgorban, A. M., Danish, S., & Datta, R. (2021) · Sustainability · doi:10.3390/su13115853 · Cited by 21 · see citing works
Fling, R. R., & Zacharewski, T. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212431 · Cited by 21 · see citing works
Exploring the effects of dietary inulin in rainbow trout fed a high-starch, 100% plant-based diet
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-023-00951-z · Cited by 20 · see citing works
Taboada, N. V., Salom, M. J. F., Córdoba, A., González, S., Alzogaray, S. L., & Nieuwenhove, C. P. V. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101836 · Cited by 19 · see citing works
Xue, W., Yuan, X., Ji, Z. J., Li, H. L., & Yao, Y. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1270920 · Cited by 20 · see citing works
Wongrattanapipat, S., Chiracharoenchitta, A., Choowongwitthaya, B., Komsathorn, P., La-ongkham, O., Nitisinprasert, S., Tunsagool, P., & Nakphaichit, M. (2021) · Food Science and Technology International · doi:10.1177/10820132211012252 · Cited by 18 · see citing works
El-Dein, A. N., Daba, G. M., Mostafa, F. A., Soliman, T. N., Awad, G. E. A., & Farid, M. A. F. (2022) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2022.102448 · Cited by 18 · see citing works
Ye, Z., Guo, T., Tang, C., Yuan, Y., Zhao, Y. D., Lu, J., Lin, J., & Guo, L. (2020) · LWT · doi:10.1016/j.lwt.2020.110563 · Cited by 17 · see citing works
Porzio, A. D., Barrella, V., Gatto, C., Cigliano, L., Spagnuolo, M. S., Crescenzo, R., Romano, I., Mauriello, G., Iossa, S., & Mazzoli, A. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105805 · Cited by 16 · see citing works
Dietary Isomalto/Malto‐Polysaccharides Increase Fecal Bulk and Microbial Fermentation in Mice
Mistry, R. H., Borewicz, K., Gu, F., Verkade, H. J., Schols, H. A., Smidt, H., & Tietge, U. J. F. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000251 · Cited by 15 · see citing works
Maftei, N.-M., Ambrose, L., Elena, D., Raileanu, C. R., Mierlan, O. L., Amariței, O., Ramos-Villarroel, A. Y., Verga, G. I., Gurau, T. V., & Gurău, G. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27052218 · Cited by 16 · see citing works
Kim, D., Min, Y., Yang, J., Heo, Y., Kim, M., Hur, C.-G., Lee, S.-C., Lee, H., Song, K., Heo, J.-Y., et al. (2021) · Animals · doi:10.3390/ani11082309 · Cited by 14 · see citing works
Holt, R. R., Barile, D., Wang, S. C., Munafo, J. P., Arvik, T. J., Li, X., Lee, F., Keen, C. L., Tagkopoulos, I., & Schmitz, H. H. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c04519 · Cited by 15 · see citing works
Ma, L., Zhao, Z., Zhao, Y., Gao, Y., Zhao, L., & Li, S. (2023) · Journal of Applied Microbiology · doi:10.1093/jambio/lxad165 · Cited by 14 · see citing works
Ścieszka, S., & Klewicka, E. (2020) · LWT · doi:10.1016/j.lwt.2020.109936 · Cited by 14 · see citing works
Zhao, Y., Song, P., Yin, S., Fan, T., Li, F., Ge, X., Liu, T., Xu, W., Su, X., & Chen, L. (2023) · Food & Function · doi:10.1039/d2fo02450k · Cited by 13 · see citing works
Safety Evaluation of a Novel Potentially Probiotic Limosilactobacillus fermentum in Rats
Neto, J. P. R. C., de Oliveira, A. M., de Oliveira, K. Á. R., Sampaio, K. B., Dutra, M. L. D. V., Freire, M. O. D. L., de Souza, E. L., & Alves, J. L. D. B. (2023) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-023-10077-3 · Cited by 13 · see citing works
Lapaquette, P., Terrat, S., Proukhnitzky, L., Martine, L., Gregoire, S., Buteau, B., Cabaret, S., Rieu, A., Bermúdez‐Humarán, L. G., Gabrielle, P., et al. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-023-00474-5 · Cited by 12 · see citing works
Wang, Q., Xiong, J., He, Y., He, J., Cai, M., Luo, Z., Zhang, T., & Zhou, X. D. (2024) · Food & Function · doi:10.1039/d4fo00369a · Cited by 13 · see citing works
Characterization and potential lipid-lowering effects of lactic acid bacteria isolated from cats
Liang, S., Kang, Y., Zhao, Y., Sun, J., Wang, X., Tao, H., Wang, Z., Wang, J., Zhong, Y., & Han, B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1392864 · Cited by 12 · see citing works
Kingkaew, E., Konno, H., Hosaka, Y., Phongsopitanun, W., & Tanasupawat, S. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e12272 · Cited by 12 · see citing works
Kar, M. J., Behbahani, B. A., Vasiee, A., Jooyandeh, H., & Taki, M. (2025) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-025-03762-0 · Cited by 10 · see citing works
Wan, J., Wu, P., Huang, J., Huang, S., Huang, Q., & Tang, X. M. (2023) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-023-03637-w · Cited by 10 · see citing works
Spangler, J. R., Caruana, J. C., Medintz, I. L., & Walper, S. A. (2021) · Future Science OA · doi:10.2144/fsoa-2020-0153 · Cited by 7 · see citing works
Mojgani, N., Bagheri, M., & Vaseji, N. (2024) · Indian Journal of Microbiology · doi:10.1007/s12088-023-01150-0 · Cited by 7 · see citing works
Liang, S., Gu, X., Sun, J., Wang, X., Tao, H., Wang, Z., Zhong, Y., Wang, J., & Han, B. (2024) · Microorganisms · doi:10.3390/microorganisms12122446 · Cited by 6 · see citing works
Hou, G., LiangKai, W., Li, R., Chen, F., Yin, J., Huang, X., & Yin, Y. (2024) · Animals · doi:10.3390/ani14121801 · Cited by 6 · see citing works
Mahamud, A. G. M. S. U., Tanvir, I. A., Kabir, M. E., Samonty, I., Chowdhury, M. A. H., & Rahman, M. A. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10501-w · Cited by 7 · see citing works
Lipid Lowering Effects of Herbal Supplements: A Review
Tan, E., & Faller, E. M. (2022) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2022.00044 · Cited by 6 · see citing works
Huang, C., Yu, S., Yu, H.-S., Tu, H., Yeh, Y., & Yu, H. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1320713 · Cited by 5 · see citing works
Behbahani, B. A., Barzegar, H., & Taki, M. (2025) · Applied Food Research · doi:10.1016/j.afres.2025.100882 · Cited by 4 · see citing works
Sidorova, Y. S., Petrov, N. A., Markova, Y. M., Kolobanov, A. I., & Zorin, S. N. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105383 · Cited by 4 · see citing works
Gupta, R., & Gaur, S. (2025) · Food Safety and Health · doi:10.1002/fsh3.70010 · Cited by 4 · see citing works
Self-citationVitamin B12 Production by Lactobacillus Species Isolated from Milk Products
Singh, B., & Sharma, S. (2022) · Journal for Research in Applied Sciences and Biotechnology · doi:10.55544/jrasb.1.2.6 · Cited by 3 · see citing works
Nair, P. P., & Annapure, U. S. (2025) · Current Microbiology · doi:10.1007/s00284-024-04028-6 · Cited by 3 · see citing works
Bernard, B., Joshi, H., & Fan, P. F. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26062679 · Cited by 4 · see citing works
de Souza, L. B., Brandão, A. B. P., Ferreira, F. G., Guzzoni, V., de Albuquerque, R. C. M. F., Mendes, L. A., Yokota, R., Porto, F. G., Casarini, D. E., Aimbire, F., et al. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.09.011 · Cited by 3 · see citing works
Szczepankowska, A. K., Cukrowská, B., & Aleksandrzak‐Piekarczyk, T. (2024) · Microbiology Resource Announcements · doi:10.1128/mra.00800-24 · Cited by 2 · see citing works
Tian, Z., Luo, J., Yuan, W., Tan, L., Xu, C., Zhou, H., Li, M., Wu, Z. F., Zhao, W., Pan, D., et al. (2025) · Journal of Dairy Science · doi:10.3168/jds.2025-27005 · Cited by 2 · see citing works
Vinothkanna, A., Dar, O. I., Chen, L., Ke, X., Sethupathy, S., Gao, Y., & Jia, A. (2025) · LWT · doi:10.1016/j.lwt.2025.118911 · Cited by 2 · see citing works
Du, M., Ye, L., Wang, C., Jiang, T., & Liu, F. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107194 · Cited by 2 · see citing works
Keathley, J., White, J., & Reid, G. (2023) · Life · doi:10.3390/life13051124 · Cited by 2 · see citing works
Amelia, R., Said, F. M., Yasmin, F., & Harun, H. (2023) · Trends in Sciences · doi:10.48048/tis.2023.6812 · Cited by 2 · see citing works
Ertürkmen, P. (2025) · Journal of Food Quality · doi:10.1155/jfq/4406517 · Cited by 2 · see citing works
The Mechanisms of Lactobacillus Activities: Probiotic Importance of Lactobacillus Species
Ahmed, R., kamil, M., Kamal, L., & Ahmed, H. (2021) · Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology · doi:10.21608/eajbse.2021.210635 · Cited by 2 · see citing works
Isolation and identification of probiotic lactobacilli from ruminant animals
Abdou, A. M., Syame, S. M., Bakry, M. A., Effat, M. M., & Fouad, E. A. (2024) · Egyptian Pharmaceutical Journal · doi:10.4103/epj.epj_222_23 · Cited by 1 · see citing works
Qin, D., Fu, W., Cui, H., Liu, H., Yang, H., Hu, Y. Q., Wang, R., Ji, X., & Wang, S. (2026) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2026.111823 · Cited by 1 · see citing works
Abadi, B. G. S., Behbahani, B. A., Jooyandeh, H., Hojjati, M., Vasiee, A., & Taki, M. (2026) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-026-04736-6 · Cited by 2 · see citing works
Zhang, C., Yang, Y., Cao, J., Li, T., Li, G., Mu, B., Feng, J., Wen, Y., Zhao, C., & Piao, C. (2026) · LWT · doi:10.1016/j.lwt.2026.119911 · Cited by 1 · see citing works
Recent technology on bio-remediation of persistent organic pollutants (POPs) and pesticides.
Takagi, K., Kataoka, R., & Yamazak, K. (2009) · Cited by 1 · see citing works
Chen, Z., Ma, J., Xia, S., Chen, Q., Yin, J., & Chen, J. (2024) · Scientia Sinica Vitae · doi:10.1360/ssv-2023-0232 · Cited by 1 · see citing works
Huang, C., Yu, H.-S., Yu, S., Tu, H., Yeh, Y., & Yu, H. (2022) · Research Square · doi:10.21203/rs.3.rs-1936247/v1
Mekanisme Konsumsi Kefir Pada Penurunan Kolesterol Darah
Rinanti, R. F., Utomo, B., & Tribudi, Y. A. (2022) · Jurnal Ilmiah Fillia Cendekia · doi:10.32503/fillia.v7i2.2333
Biological potential of kombucha constituents
Salas-Ramírez, C. A., Moreno‐Jiménez, M. R., & Manjarrez-Juanes, M. M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-13297-1.00001-2
Probiotics Potentials of Fermented Rice for Sustainable Health and Well-being
Nwinyi, O. C., & Dango, Z. G. (2025) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/1492/1/012003 · Cited by 1 · see citing works
Gastrointestinal Microbial Involvement in Gallstone Formation: A Systematic Review
Wan, S., Xia, K., Liu, Y., & Xu, H. (2025) · Health and Metabolism · doi:10.53941/hm.2025.100018
Mirza, S. S., Sanaullah, Ahmed, S., Mughal, A. S., Mammadova, K., Ashraf, M., Arshad, M. I., Alkhalifah, D. H. M., Hozzein, W. N., & Mohany, M. (2025) · Chemical Papers · doi:10.1007/s11696-025-04211-4
Nakano, A., Kawata, D., Ueno, H., Tatara, Y., Ishida, M., Tamada, Y., Mikami, T., Murashita, K., & Itoh, K. (2025) · International Dairy Journal · doi:10.1016/j.idairyj.2025.106445
Almatrafi, M. M., Nada, A. H., Doghish, A. S., Elebeedy, D., Ghanem, A., Fayad, E., El-Mekkawy, H. I., Mohammed, O. A., Elkhawaga, S. Y., Alshaya, D. S., et al. (2025) · Folia Microbiologica · doi:10.1007/s12223-025-01346-5
Grześkowiak, Ł., Ipharraguerre, I. R., Rimbach, G. H., Vahjen, W., & Zentek, J. (2025) · Journal of Nutritional Science · doi:10.1017/jns.2025.10050
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26670483
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26670495
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26670486
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26670492
Defaix, R., Lokesh, J., Frohn, L., Béchec, M. L., Pigot, T., Véron, V., Surget, A., Biasutti, S., Terrier, F., Cassy, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26670489
Impact du microbiome intestinal sur la cholestérolémie : concepts et applications
Bourgin, M. (2021) · theses.fr (ABES) · doi:10.70675/5ef61a78z31c7z44fazafa1zd4a5749a4aaf
Asiegbu, C. V., & Tabit, F. T. (2026) · Scientific Reports · doi:10.1038/s41598-026-47302-2
Zambrano-Cervantes, M., Rendón-Rosales, M. Á., Beltrán‐Barrientos, L. M., Torres‐Llanez, M. J., González-Córdova, A. F., Hernández‐Mendoza, A., & Vallejo‐Córdoba, B. (2026) · International Dairy Journal · doi:10.1016/j.idairyj.2026.106735
Sigali, S. D. S., Bierhals, C. K., Siqueira, M. F. F., Ramson, J., Viana, P. F., Kröning, I. S., Massaut, K. B., Alves, M. I., Moreira, A. D. S., Gularte, M. A., et al. (2026) · European Food Research and Technology · doi:10.1007/s00217-026-05214-5
Liu, Y., Xia, Y., & Chen, Y. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109973
Thakur, G., Kumar, R., Negi, R., Sharma, B., Yadav, N., Shreaz, S., & Yadav, A. N. (2026) · Food and Humanity · doi:10.1016/j.foohum.2026.101502
- Authors
- Khare, A., & Gaur, S.
- Affiliations
- Jaypee Institute of Information Technology (IN)
- Corresponding author
- Gaur, Smriti
- Venue
- Current Microbiology
- Published
- 2020-02-04
- Volume
- 77
- Issue
- 4
- Pages
- 638-644
- ISSN
- 0343-8651 (ISSN-L)
- 1432-0991
- OpenAlex
- W3004639068
- Cited by
- 100
- References
- 53
- Citations by year
- 2026: 11 · 2025: 17 · 2024: 25 · 2023: 15 · 2022: 13 · 2021: 12 · 2020: 6
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- Lactobacillus, probiotics, cholesterol lowering, bile salt hydrolase, bile acid deconjugation, taurine, glycine, short-chain fatty acids, propionate, cholesterol metabolism, gut microbiota, gut health
- MeSH terms
- Gastrointestinal Microbiome, Bile Acids and Salts, Cholesterol, Humans, Lactobacillus, Phylogeny, Probiotics, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
