Cited by 214Dementia and Cognitive Impairment ResearchPhytochemicals and Antioxidant ActivitiesNutritional Studies and Diet

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Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia

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Kent, Katherine, Charlton, Karen, Roodenrys, Steven, Batterham, Marijka, Potter, Jan, Traynor, Victoria, Gilbert, Hayley, Morgan, Olivia, Richards, Rachelle·2017·European Journal of Nutrition

DOI 10.1007/s00394-015-1083-y

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Abstract

Purpose Dietary flavonoids, including anthocyanins, may positively influence cognition and may be beneficial for the prevention and treatment of dementia. We aimed to assess whether daily consumption of anthocyanin-rich cherry juice changed cognitive function in older adults with dementia. Blood pressure and anti-inflammatory effects were examined as secondary outcomes.Methods A 12-week randomised controlled trial assessed cognitive outcomes in older adults (+70 year) with mild-to-moderate dementia (n = 49) after consumption of 200 ml/day of either a cherry juice or a control juice with negligible anthocyanin content. Blood pressure and inflammatory markers (CRP and IL-6) were measured at 6 and 12 weeks. ANCOVA controlling for baseline and RMANOVA assessed change in cognition and blood pressure.Results Improvements in verbal fluency (p = 0.014), short-term memory (p = 0.014) and long-term memory (p ≤ 0.001) were found in the cherry juice group. A significant reduction in systolic (p = 0.038) blood pressure and a trend for diastolic (p = 0.160) blood pressure reduction was evident in the intervention group. Markers of inflammation (CRP and IL-6) were not altered.Conclusion Inclusion of an anthocyanin-rich beverage may be a practical and feasible way to improve total anthocyanin consumption in older adults with mild-to-moderate dementia, with potential to improve specific cognitive outcomes.

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Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Dietary Intake of Antioxidants and Risk of Alzheimer Disease
Engelhart, M. J. (2002) · JAMA · doi:10.1001/jama.287.24.3223 · Cited by 1,080 · cited 1×
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Background
Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
Vauzour, D., Rodriguez‐Mateos, A., Corona, G., Oruña-Concha, M. J., & Spencer, J. P. E. (2010) · Nutrients · doi:10.3390/nu2111106 · Cited by 885
The Lawton instrumental activities of daily living scale
Graf, C. (2008) · AJN, American Journal of Nursing · doi:10.1097/01.naj.0000314810.46029.74 · Cited by 832 · cited 2×
“Lawton’s Instrumental Activities of Daily Living Scale (IADL) (21) determined functional impairment and hand grip strength was assessed using a digital Jamar handgrip dynamometer (Lafayette”
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Krikorian, R., Shidler, M. D., Nash, T. A., Kalt, W., Vinqvist-Tymchuk, M. R., Shukitt-Hale, B., & Joseph, J. A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9029332 · Cited by 582 · cited 4×
“4 Preliminary dietary supplementation studies have shown that blueberries (11) and concord grapes (12, 13) improve aspects of memory in older adults over a 12 and 16 week intervention.”
BackgroundMethodResultInfluential
The neuroprotective potential of flavonoids: a multiplicity of effects
Vauzour, D., Vafeiadou, K., Rodriguez‐Mateos, A., Rendeiro, C., & Spencer, J. P. E. (2008) · Genes & Nutrition · doi:10.1007/s12263-008-0091-4 · Cited by 561 · cited 1×
“Their antioxidant actions assist to scavenge free radicals in the brain (8), while their neuro-protective effects include protection of vulnerable neurons against inflammation, enhancement of existing neuronal function, increased blood flow to the brain and neurogenesis initiation in areas of the brain that are associ…”
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Paradela, E. M. P., Lourenço, R. A., & Veras, R. P. (2005) · Revista de Saúde Pública · doi:10.1590/s0034-89102005000600008 · Cited by 450 · cited 1×
“The geriatric depression scale (GDS) (29) assessed mood state.”
Background
Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease
Williams, R. J., & Spencer, J. P. E. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.010 · Cited by 448 · cited 2×
“The ability of flavonoids to modulate Alzheimer’s disease progression is still poorly understood (17).”
Background
Flavonoids: modulators of brain function?
Spencer, J. P. E. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508965776 · Cited by 385

Show all 39 references

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USDA (2013) United States Department of Agriculture Database for the flavonoid content of selected foods. Release 3:1

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“In addition, the studies that measured the efficacy of memory also showed mixed results, whereby the studies from several studies [34–36, 39, 42] showed a significant result, whereas studies from others did not [33, 37, 38].”
BackgroundMethodResultInfluential
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Background
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Kent, K., Roodenrys, S. J., Charlton, K. E., Richards, R., Morgan, O., & Gilbert, H. (2016) · Journal of Aging Research and Lifestyle · doi:10.14283/jarcp.2016.95 · Cited by 8
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“The results of our study derive strong support from the previous study that consumption of anthocyanin showed significant improvement in memory and cognitive impairment [25].”
MethodResult
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“For example, using a randomised controlled trial, Kent et al., demonstrated that the daily consumption of anthocyanin-rich cherry juice for 12 weeks improved measures of verbal learning and memory in older adults living with dementia [12].”
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“When cherry juice was compared to apple juice as a control (200 mL/day, 12 weeks) in participants with mild-to-moderate Alzheimer’s type dementia, no significant differences in IL-6 levels between groups were observed [79].”
Anthocyanins: Coloured Bioactive Compounds in Potatoes
Mishra, T., Luthra, S. K., Raigond, P., & Bandana (2020) · Springer eBooks · doi:10.1007/978-981-15-7662-1_10 · Cited by 4
Assessing the Role of Dark Sweet Cherry (Prunus avium L.) Consumption on Cognitive Function, Neuropeptides, and Circadian Rhythm in Obesity: Results from a Randomized Controlled Trial
Arbizu, S., Mertens‐Talcott, S. U., Talcott, S. T., Riviere, A. J., Riechman, S. E., & Noratto, G. D. (2025) · Nutrients · doi:10.3390/nu17050784 · Cited by 5
“Overall, the mechanism of action behind polyphenols’ cognitive enhancement properties is thought to be exerted by their capacity to mitigate inflammatory markers, resulting in blood pressure-lowering effects [25].”
Influential
Berry Supplementation and Their Beneficial Effects on Some Central Nervous System Disorders
Fernández-Demeneghi, R., Vargas-Moreno, I., Héctor-Gabriel, A.-M., et al. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.90428 · Cited by 4
Fruits
Mohammed, S. G. A. A., & Qoronfleh, M. W. (2020) · Advances in neurobiology · doi:10.1007/978-3-030-30402-7_10 · Cited by 5
Dietary Polyphenols to Maintain Healthier Brain Measures and Cognitive Function, as Mediated by Gut Microbiota Metabolites
Mayer, E. A., Horn, J. V., Mayer, D. E., & Randolph, E. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99971-7.00014-x · Cited by 4
The Neuroprotective Potential of Polyphenols in Neurodegenerative Diseases
Wojciechowska, O. (2024) · Food Science and Nutrition Cases · doi:10.1079/fsncases.2024.0005 · Cited by 4
Associations of flavonoid intakes with metabolic dysfunction-associated steatotic liver disease in US adults
He, Y., Chang, Y., Liu, X., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0322797 · Cited by 3
Effects of Oral Anthocyanin Supplementation on In Vitro Neurogenesis, Hippocampus-Dependent Cognition, and Blood-Based Dementia Biomarkers: Results from a 24-Week Randomized Controlled Trial in Older Adults At Risk for Dementia (ACID)
de Lucia, C., Tovar, D., Khalifa, K. N., Kvernberg, S. M., Pola, I., Bergland, A. K., Maple‐Grødem, J., Siow, R. C. M., Ashton, N. J., Ballard, C. G., et al. (2025) · Nutrients · doi:10.3390/nu17162680 · Cited by 3
Influence of Conservation Methods on the sour cherry (Cerasus vulgaris Mill.) fruits quality
Kovaleva, T. Y., Bokov, D. O., Sergunova, E. V., et al. (2024) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2024.00382 · Cited by 3
PLANT ANTIOXIDANTS AND THEIR NON-TRADITIONAL SOURCES (review)
Goncharova, Y. K. (2024) · Sel skokhozyaistvennaya Biologiya · doi:10.15389/agrobiology.2024.1.39eng · Cited by 3
Relative Validity and Reproducibility of an Interviewer Administered 14-Item FFQ to Estimate Flavonoid Intake Among Older Adults with Mild-Moderate Dementia
Kent, K., & Charlton, K. E. (2017) · Journal of Nutrition in Gerontology and Geriatrics · doi:10.1080/21551197.2017.1321080 · Cited by 3
“The current study utilized dietary data collected as a part of a randomized controlled trial, which investigated the impact of anthocyanin-rich cherry juice on cognitive outcomes in older adults with dementia (24).”
Method
Mineral contents of Ethiopian red and green apple fruits: A comparison with WHO/FAO standardsPreprint
International, C. C. (2021) · doi:10.31219/osf.io/w7mqa · Cited by 3
Queen garnet plum juice supplementation does not provide additional cognitive benefits over a group-based memory program in older adults with mild cognitive impairment: A randomized clinical trial
May, N., Fitzgerald, Z., Broyd, S. J., do Rosario, V. A., Roodenrys, S. J., Bliokas, V. V., Thomas, S. J., Potter, J., George, J., Weston–Green, K., et al. (2025) · Nutrition Research · doi:10.1016/j.nutres.2025.04.006 · Cited by 2
Impact of anthocyanin-rich black rice consumption on cognitive function, inflammation and microvascular function in older adults: a crossover intervention trial
Mekhora, C., Lamport, D. J., & Spencer, J. P. E. (2026) · Food & Function · doi:10.1039/d5fo04351d · Cited by 2
The effect of anthocyanins through diet and supplementation on cognitive function in older adults: a multi-centre randomised controlled clinical trial
do Rosario, V. A., Chan, K., Lorzadeh, E., Brodaty, H., Anstey, K. J., Kent, K., Roodenrys, S. J., Bliokas, V. V., Phillipson, L., François, M. E., et al. (2026) · Food & Function · doi:10.1039/d5fo05366h · Cited by 2
The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children
Soltanifar, A., Moharreri, F., Bakhtiari, E., & Hosseinpour, A. (2022) · Journal of Attention Disorders · doi:10.1177/10870547221129307 · Cited by 2
“…improving sleep quality (Howatson et al., 2012; Özen & Ekşi, 2016; Pigeon et al., 2010) as well as improving cognitive function (Chai et al., 2019; Kent et al., 2017; Kimble et al., 2022) and anti-neurodegenerative activity (Kim et al., 2005; Thangthaeng et al., 2016), it seems that consumption…”
BackgroundInfluential
Protective Effects of Cherry Extract on Malondialdehyde Levels, Catalase Activity, and Edema Induced by Middle Cerebral Artery Occlusion in a Rat Stroke Model
Alavian, F., Alavian, K., Ghiasvand, S., & Rezaeian, L. (2020) · The Neuroscience Journal of Shefaye Khatam · doi:10.29252/shefa.8.3.1 · Cited by 2
Black rice bran intake reduces phosphorylated tau levels and enhances insulin signaling in the brain of aged normal mice
Hara, T., Toyama, H., Ohata, Y., Ikeuchi, T., Nakamura, S., Joh, T., & Ohtsubo, K. (2022) · Bioscience Biotechnology and Biochemistry · doi:10.1093/bbb/zbac125 · Cited by 2
Efficacy of dietary polyphenols for neuroprotective effects and cognitive improvements
Divya, C., Amalraj, A., & Gopi, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820593-8.00012-4 · Cited by 1
Cherry Juice Improves Memory and Anxiety by Modulating Cell Number in the Hippocampus of Male Rat Pups Infected with Lipopolysaccharides During Gestation and Gestation-Lactation
Gen, J. J. V., Alvarado-Olivarez, M., Guzmán‐Gerónimo, R. I., González-Nieto, P. F., Gutiérrez‐García, A. G., & Oliart‐Ros, R. M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125642 · Cited by 1
“One study showed that consumption of anthocyanin-rich cherry juice improved memory in older adults [40].”
Daily Intake of Recommended Servings of Fruit Improves Nutrient Intake but Shows no Major Effect on Cardiovascular Health or Cognition in Low Fruit Consumers
Zingales, S., Martinez, J., Stepp, A. H., Miller, C., Jason, N., Hong, M. Y., Liu, C., Kern, M., & Hooshmand, S. (2025) · Current Developments in Nutrition · doi:10.1016/j.cdnut.2025.107544 · Cited by 1
“Another study found that the consumption of a daily serving of 200 mL of anthocyanin-rich cherry juice improved verbal learning, memory, and executive function after 12 wk in adults 70 y old and older with mild-to-moderate dementia [50].”
Preparation of Blueberry Anthocyanin Nanoemulsions and Their Stability and Skin Safety Evaluation
Mingyue, Y. I. N., Song, J., Zhou, X., et al. (2023) · Materials Research and Development · doi:10.57237/j.mater.2023.04.001 · Cited by 1
Exploring the Potential of Bioactive Compounds as Interventions for Dementia: Current Insights and Future Directions
Nicholas‐Okpara, V. A. N., Adegboyega, M. O., Oben, J. E., Williams, L., Anastasia, U., Jemima, R., Collins, A., & Ubaka, A. J. (2024) · Functional Food Science · doi:10.31989/ffs.v4i5.1329 · Cited by 1
“Additionally, cherries contain melatonin, which is reported to mitigate nitric oxide synthase and promote the production of antioxidant enzymes [14].”
BackgroundInfluential
Anthocyanins: Pharmacology and Nutraceutical Importance
Alam, M. S., Maity, M. K., Nazmi, A. S., & Ali, M. Y. (2024) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815223880124010009 · Cited by 1
Pelargonidin exhibits restoring effects against amyloid β-induced deficits in the hippocampus of male rats
Asl, S. S., Bergen, H., Ashtari, N., Amiri, S., Łoś, M., & Mehdizadeh, M. (2019) · Medical Journal of the Islamic Republic of Iran · doi:10.47176/mjiri.33.135 · Cited by 1
Asociaciones entre dieta y función cognitiva en el Proyecto SUN
Muñoz, M. I. (2022) · Deposito Adademico Digital Universidad De Navarra (University of Navarra) · doi:10.15581/10171/63292 · Cited by 1
Dietary Patterns, Foods and Beverages in Age-Related Cognitive Performance and Dementia
Dreher, M. L. (2018) · Springer eBooks · doi:10.1007/978-3-319-59180-3_18
Nutritional Interventions to Improve Cognitive Function
Roodenrys, S. J. (2020) · Springer eBooks · doi:10.1007/978-981-15-6771-1_4
Sugary beverage intake and genetic risk of dementia in relation to incident dementia and brain structure: evidence from the UK BiobankPreprint
Chen, H., Chen, J., Cao, Y., Sun, Y., Huang, L., Ji, J. S., Shen, J., Zheng, Y., Zong, G., & Yuan, C. (2021) · Research Square · doi:10.21203/rs.3.rs-882320/v1
Sugary beverage intake and genetic risk in relation to brain structure and incident dementia: evidence from the UK BiobankPreprint
Chen, H., Chen, J., Cao, Y., Sun, Y., Huang, L., Ji, J. S., Voortman, T., Vernooij, M. W., Shen, J., Zheng, Y., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-882320/v2
“Other short-term interventional studies also presented similar results that juice intake was associated with slowed cognitive decline and lowered risk of cognitive impairment[29,30].”
Result
Черешня (лат. Prúnus ávium)
Татьяна, Е., & Алексей, Я. (2019) · Журнал здорового питания и диетологии · doi:10.59316/.vi8.41
Investigating dietary recommendations, particularly tart cherries, in gout and cardiovascular disease management
Lamb, K. L. (2023) · Sheffield Hallam University · doi:10.7190/shu-thesis-00517
Вишневый сок — ароматный напиток здоровья и долголетия, 11 научных доказательств
Наталья, Т., & Татьяна, Е. (2023) · Журнал здорового питания и диетологии · doi:10.59316/j.edaplus.2023.25.1
Investigation of the Effect of Annealing Conditions on Chemical Bath Deposited CdTe Thin- film from Non-Aqueous Bath
Surabhi, S., Anurag, K., & Kumar, S. R. (2024) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815238846124010009
Exploring Functional Foods in Prevention of Dementia
Azar, O. L., Fereidouni, A., & Shanjani, S. M. (2024) · Nutritional neurosciences · doi:10.1007/978-981-97-4117-5_8
Capítulo 6: Efecto de los polifenoles de los alimentos en la salud cardiovascular
(USC), U. D. S. D. C., Lence, J. P., Cardelle‐Cobas, A., (USC), U. D. S. D. C., Vázquez, B. I., (USC), U. D. S. D. C., Cepeda, A., & (USC), U. D. S. D. C. (2024) · doi:10.59899/impo-anti-c6
Multifaceted benefits of anthocyanins and their derivatives in health and disease: A systematic review
Kaur, P., Buttar, H. S., Wilson, D. W., Télessy, I. G., & Garg, V. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22300-6.00036-x
Upcycling of Waste Cherries Produces an Anthocyanin-Rich Powder That Protects Against Amyloid-β Toxicity in C. elegans
Blackburn, S. A., Sullivan, W. G., Freeman, L. M., Howland, K., Karamalegos, A. A., Dallaway, M., Philo, M. R., Tullet, J. M. A., & Ezcurra, M. (2025) · Antioxidants · doi:10.3390/antiox14080995
“Less is known about using cherry-based supplements, but consumption of anthocyanin-rich cherry juice for 12 weeks has been shown to improve memory and cognition in older adults with mild-to-moderate dementia [29].”

Authors: Kent, K., Charlton, K., Roodenrys, S., Batterham, M., Potter, J., Traynor, V., Gilbert, H., Morgan, O., & Richards, R.
Affiliations: University of Wollongong (AU)
Wollongong Hospital (AU)
Corresponding author: Kent, Katherine
ORCID: Kent, Katherine
Charlton, Karen
Roodenrys, Steven
Batterham, Marijka
Traynor, Victoria
Venue: European Journal of Nutrition
Publisher: Springer Science and Business Media LLC
Published: 2015-10-19
Volume: 56
Issue: 1
Pages: 333-341
ISSN: 0044-264X (ISSN-L)
1436-6207
1435-1293
DOI: 10.1007/s00394-015-1083-y
OpenAlex: W1786564295
Cited by: 214
References: 39
Citations by year: 2026: 12 · 2025: 17 · 2024: 25 · 2023: 19 · 2022: 24 · 2021: 24 · 2020: 31 · 2019: 30 · 2018: 19 · 2017: 7 · 2016: 6
FWCI: 8.65
Type: journal article
Language: en
Open access: green
figshare.com
Licence: cc-by
www.springer.com/tdm (tdm)
Locations: Zeitschrift für Ernährungswissenschaft (publishedVersion)
PubMed (publishedVersion)
eCite Digital Repository (University of Tasmania) (submittedVersion)
Research Online (University of Wollongong) (submittedVersion)
Figshare (submittedVersion, cc-by)
Figshare (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords: anthocyanins, cherry juice, dementia, cognitive function, memory, older adults, dietary flavonoids, blood pressure, inflammation, C-reactive protein, interleukin-6, verbal fluency
MeSH terms: Fruit and Vegetable Juices, Prunus avium, Aged, Anthocyanins, Ascorbic Acid, Blood Pressure, C-Reactive Protein, Cognition, Dementia, Female, Follow-Up Studies, Fruit, Humans, Male, Memory, Biomarkers, Nutrition Assessment, Interleukin-6, Body Mass Index, Hand Strength

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Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia

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