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Effectiveness of mindfulness-based cognitive therapy for comorbid depression and anxiety in pregnancy: a randomized controlled trial
Abstract
Pregnant women are at high risk of mood and anxiety disorders, and options for non-pharmacological treatment are limited. Mindfulness-based cognitive therapy (MBCT) has strong evidence among people with mood and anxiety disorders, but limited studies reported the effectiveness of MBCT on perinatal comorbid conditions. This study aimed to examine the effects of an 8-week MBCT intervention on pregnant women with comorbid depression and anxiety. In this randomized controlled study, 38 pregnant women with a diagnosis of depression and varying levels of comorbid anxiety disorders were randomly assigned to either MBCT or a control group. Scores on the Beck Depression Inventory-II, Beck Anxiety Inventory, Emotion Regulation Questionnaire, and Scales of Psychological Wellbeing were used as outcome measures at baseline, after MBCT, and through 1-month follow-up. Intent to treat analyses provided preliminary evidence that MBCT can be effective in reducing depressive and anxiety symptoms and in enhancing the use of adaptive emotion regulation strategies and psychological well-being. Improvements in outcomes were maintained 1 month. Results provide cross-cultural support for MBCT as a treatment for depression and anxiety in pregnant women. This brief and non-pharmacological treatment can be used to improve maternal psychological health.
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“MBSR and similar mindfulness-based interventions (MBIs) have been shown efficacious at reducing depressive and anxiety symptoms in pregnancy and postpartum, but sleep quality was not a key outcome in these studies [12, 13].”
From Online prenatal trial in mindfulness sleep management (OPTIMISM): Protocol for a pilot randomized controlled trial (2020) · cites this paper as [13]
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Metadata
- Authors
- Zemestani, M., & Fazeli Nikoo, Z.
- Affiliations
- University of Kurdistan (IR)
- Corresponding author
- Zemestani, Mehdi
- ORCID
- Zemestani, Mehdi
- Venue
- Archives of Women's Mental Health
- Published
- 2019-04-13
- Volume
- 23
- Issue
- 2
- Pages
- 207-214
- ISSN
- 1434-1816 (ISSN-L)
- 1435-1102
- OpenAlex
- W2939754372
- Cited by
- 127
- References
- 54
- Citations by year
- 2026: 14 · 2025: 20 · 2024: 25 · 2023: 27 · 2022: 19 · 2021: 17 · 2020: 3 · 2019: 1
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Archives of Women s Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- mindfulness-based cognitive therapy, perinatal depression, perinatal anxiety, comorbid depression and anxiety, pregnancy, non-pharmacological treatment, emotion regulation, psychological well-being, maternal mental health
- MeSH terms
- Adult, Anxiety, Anxiety Disorders, Depression, Depressive Disorder, Female, Humans, Iran, Pregnancy, Psychiatric Status Rating Scales, Surveys and Questionnaires, Comorbidity, Cognitive Behavioral Therapy, Treatment Outcome, Mindfulness
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