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Assessing biological aging: the origin of deficit accumulation
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“In59,60, the authors suggested that the exponential growth of disease burden observed in the National Population Health Survey of Canadians over 20 y.o. could be explained by an age-related decrease in organism recovery in the face of a constant rate of exposure to environmental stresses.”
From Longitudinal Analysis of Blood Markers Reveals Progressive Loss of Resilience and Predicts Human Lifespan Limit (2021) · cites this paper as [59]
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Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
Accumulation of Deficits as a Proxy Measure of Aging
Mitnitski, A. B., Mogilner, A. J., & Rockwood, K. (2001) · The Scientific World JOURNAL · doi:10.1100/tsw.2001.58 · Cited by 2,893 · cited 4×
“While many of the variables, when considered in isolation from each other, have only small effects on health, their cumulative effect becomes significant (Mitnitski et al. 2001, 2002; Kulminski et al. 2007).”
InfluentialSelf-citationPrevalence and 10‐Year Outcomes of Frailty in Older Adults in Relation to Deficit Accumulation
Song, X., Mitnitski, A., & Rockwood, K. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02764.x · Cited by 1,104 · cited 2×
“The model allows an understanding of the major patterns in deficits accumulation observed in many studies by our group (e.g., Mitnitski et al. 2001, 2005; Rockwood and Mitnitski 2006; Song et al. 2010) and others (Garcı́aGonzález et al.”
Self-citationOperationalizing a frailty index from a standardized comprehensive geriatric assessment
Jones, D. M., Song, X., & Rockwood, K. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52521.x · Cited by 605
Self-citationProtein Homeostasis and Aging: the importance of exquisite quality control
Koga, H., Kaushik, S., & Cuervo, A. M. (2011) · Ageing research reviews · doi:10.1016/j.arr.2010.02.001 · Cited by 476
The role of DNA damage and repair in aging through the prism of Koch-like criteria
Moskalev, A. A., Shaposhnikov, M. V., Plyusnina, E. N., Zhavoronkov, A., Budovsky, A., Yanai, H., & Fraifeld, V. E. (2013) · Ageing Research Reviews · doi:10.1016/j.arr.2012.02.001 · Cited by 387
The network and the remodeling theories of aging: historical background and new perspectives
Franceschi, C., Valensin, S., Bonafè, M., Paolisso, G., Yashin, A. I., Monti, D., & De Benedictis, G. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00172-8 · Cited by 335 · cited 1×
“A large body of evidence can relate an increase in recovery time to age-associated damages and diseases (Franceschi et al. 2000; Rattan 2003; Gurtner et al. 2008; Akushevich et al. 2013; Yanai et al. 2011).”
Jones, D., Song, X., Mitnitski, A., & Rockwood, K. (2005) · Aging Clinical and Experimental Research · doi:10.1007/bf03327413 · Cited by 267
Self-citationScheffer, M. (2010) · Nature · doi:10.1038/467411a · Cited by 238
Stochastic model for analysis of longitudinal data on aging and mortality
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Self-citation
Metadata
- Authors
- Mitnitski, A., Song, X., & Rockwood, K.
- Venue
- Biogerontology
- Published
- 2013-07-17
- Volume
- 14
- Issue
- 6
- Pages
- 709-717
- ISSN
- 1389-5729
- 1573-6768
- PMC
- PMC3847281
- Cited by
- 159
- References
- 10
- Language
- en
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