Dopamine: Functions, Signaling, and Association with Neurological Diseases

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Scalable fabrication of graphene-assembled multifunctional electrode with efficient electrochemical detection of dopamine and glucose

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Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe?

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Gait impairment-related axonal degeneration in Parkinson’s disease by neurite orientation dispersion and density imaging

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Dopaminergic dysfunction in the left putamen of patients with major depressive disorder

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Engineering human midbrain organoid microphysiological systems to model prenatal PFOS exposure

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Silane-Functionalized MXene-PEGDA Hydrogel for Enhanced Electrochemical Sensing of Neurotransmitters and Antioxidants

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Emotion Induced Monoamine Neuromodulator Release Affects Functional Neurological Disorders

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Targeting mitochondrial dynamics of morphine-responsive dopaminergic neurons ameliorates opiate withdrawal

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Emerging Functions of Neuromodulation during Sleep

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CMOS Point-of-Care Diagnostics Technologies: Recent Advances and Future Prospects

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Natural flavonoids from herbs and nutraceuticals as ferroptosis inhibitors in central nervous system diseases: current preclinical evidence and future perspectives

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Electrochemical sensing platform based on the synergistic effects of MWCNTs and ZIF-L (Zn, Co) for voltammetric determination of dopamine in the presence of uric acid

Bazrafkan, A., Nejad, F. G., Zaimbashi, R., & Beitollahi, H. (2025) · Electrochemistry Communications · doi:10.1016/j.elecom.2025.107928 · Cited by 20

Involvement of dopamine receptor in the actions of non-psychoactive phytocannabinoids

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PET imaging of animal models with depressive-like phenotypes

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High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation

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Dl-3-n-butylphthalide activates Nrf2, inhibits ferritinophagy, and protects MES23.5 dopaminergic neurons from ferroptosis

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Density Functional Theory-Assisted Electrochemical Assay Manipulated by a Donor–Acceptor Structure toward Pharmaceutical Diagnostic

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Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor

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The Potential Role of Dopamine in Mediating Motor Function and Interpersonal Synchrony

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Visualization of differential GPCR crosstalk in DRD1-DRD2 heterodimer upon different dopamine levels

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Cognitive Functions, Neurotransmitter Alterations, and Hippocampal Microstructural Changes in Mice Caused by Feeding on Western Diet

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Recent Advances in Catecholamines Analytical Detection Methods and Their Pretreatment Technologies

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Elucidating the toxicity mechanisms of organophosphate esters by adverse outcome pathway network

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A high-performance wearable microneedle sensor based on a carboxylated carbon nanotube-carbon nanotube composite electrode for the simultaneous detection of uric acid and dopamine

Zhu, J., Wang, W., Chen, G., Gao, Z., Gao, Z., Wang, L., Wang, L., & Cai, W. (2024) · Microchemical Journal · doi:10.1016/j.microc.2024.111607 · Cited by 19

Association Between Stress, Neuroinflammation, and Irritable Bowel Syndrome: The Positive Effects of Probiotic Therapy

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The potential of dopamine receptor D2 (DRD2) as a therapeutic target for tackling pancreatic cancer

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Innovative screening models for the discovery of new schizophrenia drug therapies: an integrated approach

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Atrazine’s effects on mammalian physiology

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Self-referenced ratiometric electrochemical biosensor based on covalent organic framework assembled MXene for stain-resistance and sensitive sensing of dopamine

Yang, Z., Guo, H., Sun, L., Yu, Z., & Yang, W. (2025) · Talanta · doi:10.1016/j.talanta.2025.128614 · Cited by 18

A Neurodevelopmental Model of Combined Pyrethroid and Chronic Stress Exposure

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Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions

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Advances and Challenges of Cannabidiol as an Anti-Seizure Strategy: Preclinical Evidence

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Enhancement of Dopamine Electrochemical Detection with Manganese Doped Crystalline Copper Oxide

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Neuromodulation in Parkinson’s disease targeting opioid and cannabinoid receptors, understanding the role of NLRP3 pathway: a novel therapeutic approach

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DNAJC12 in Monoamine Metabolism, Neurodevelopment, and Neurodegeneration

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Pathogenic Impact of Fatty Acid-Binding Proteins in Parkinson’s Disease—Potential Biomarkers and Therapeutic Targets

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Impulse control disorders in Parkinson’s disease patients treated with pramipexole and ropinirole: a systematic review and meta-analysis

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Early-life perfluorooctanoic acid exposure disrupts the function of dopamine transporter protein with glycosylation changes implicating the links between decreased dopamine levels and disruptive behaviors in larval zebrafish

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Recent Progress in Organic Electrochemical Transistor-Structured Biosensors

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Early‐Motor Phenotype Relates to Neuropsychiatric and Cognitive Disorders in Huntington's Disease

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Processed Food–Sweets Patterns and Related Behaviors with Attention Deficit Hyperactivity Disorder among Children: A Case–Control Study

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New Insight into the Function of Dopamine (DA) during Cd Stress in Duckweed (Lemna turionifera 5511)

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Electrochemical imaging of neurotransmitter release with fast-scan voltammetric ion conductance microscopy

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A comprehensive review on the enzyme-free electrochemical dopamine Sensing: Development and challenges since inception

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The Aversion Function of the Limbic Dopaminergic Neurons and Their Roles in Functional Neurological Disorders

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Electrically Copolymerized Polydopamine Melanin/Poly(3,4-ethylenedioxythiophene) Applied for Bioactive Multimodal Neural Interfaces with Induced Pluripotent Stem Cell-Derived Neurons

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Cyclic dipeptides and the human microbiome: Opportunities and challenges

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A study of screen-printed electrodes modified with MoSe2 and AuNPs-MoSe2 nanosheets for dopamine sensing

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The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions

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Chemical Proteomic Profiling of Protein Dopaminylation in Colorectal Cancer Cells

Zhang, N., Gao, S., Peng, H., Wu, J., Li, H., Gibson, C., Wu, S., Zhu, J., & Zheng, Q. (2024) · Journal of Proteome Research · doi:10.1021/acs.jproteome.4c00379 · Cited by 17

Depression and anxiety symptoms correlate with diurnal preference, sleep habits, and Per3 VNTR polymorphism (rs57875989) in a non-clinical sample

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Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples

Holland, E. B., & Pessah, I. N. (2020) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2020.104842 · Cited by 17

Acute hydrogen sulfide-induced neurochemical and morphological changes in the brainstem

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Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor–Receptor Interactions

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Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival

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Electroencephalography connectome changes in chronic insomnia disorder are correlated with neurochemical signatures

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NR4A2 as a Novel Target Gene for Developmental and Epileptic Encephalopathy: A Systematic Review of Related Disorders and Therapeutic Strategies

Gabaldón-Albero, A., Mayo, S., & Martı́nez, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105198 · Cited by 16

Why is vestibular migraine associated with many comorbidities?

Ma, Y., Zhang, D., Zhang, H., Cao, F., Zhou, Y., Wu, B., Wang, L.-Z., & Xu, B. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12692-8 · Cited by 17

Molecular Anatomy of Synaptic and Extrasynaptic Neurotransmission Between Nociceptive Primary Afferents and Spinal Dorsal Horn Neurons

Antal, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26052356 · Cited by 21

Cell Viability and Drug Evaluation Biosensing System Based on Disposable AuNPs/MWCNT Nanocomposite Modified Screen-Printed Electrode for Exocytosis Dopamine Detection

Liu, M., Zhang, F., Liu, H., Wu, M., Liu, Z.-J., & Huang, P. (2022) · Talanta · doi:10.1016/j.talanta.2022.124118 · Cited by 16

A review of the potential adverse health impacts of atrazine in humans

Arabi, S., Heidari‐Beni, M., Poursafa, P., Roshanaei, M., & Kelishadi, R. (2024) · Reviews on Environmental Health · doi:10.1515/reveh-2024-0094 · Cited by 18

Self-Assembly of 3D-Printed Multiscale Micropillar-Based Organic Electrochemical Transistors for Ultrasensitive Dopamine Sensing

Zhou, X., Zhang, L., Zhang, S., Liang, J., Zhang, K., Zhao, Z., Zhao, S., Wang, Y., Guo, Y., Zhang, D., et al. (2025) · ACS Nano · doi:10.1021/acsnano.5c02784 · Cited by 15

Dopamine and the Gut Microbiota: Interactions Within the Microbiota–Gut–Brain Axis and Therapeutic Perspectives

Barbu, A. C., Stoleru, S., Zugravu, A., Poenaru, E., Dragomir, A.-F., Costescu, M., Aurelian, S. M., Shhab, Y., Stoleru, C. M., Coman, O. A., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010271 · Cited by 20

Dopamine Homeostasis Imbalance and Dopamine Receptors-Mediated AC/cAMP/PKA Pathway Activation are Involved in Aconitine-Induced Neurological Impairment in Zebrafish and SH-SY5Y Cells

Zhou, J., Peng, C. Y., Li, Q., Yan, X., Yang, L., Li, M., Cao, X., Xie, X., Chen, D., Rao, C., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.837810 · Cited by 15

Analgesia and pain: Dual effect of dopamine on the peripheral nociceptive system is dependent on D2-or D1–like receptor activation

de Queiroz, B. F. G., Fonseca, F. C. D. S., Ferreira, R. C. M., Romero, T. R. L., Perez, A. C., & Duarte, I. D. G. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174872 · Cited by 15

Effects of biotin deficiency on short term memory: The role of glutamate, glutamic acid, dopamine and protein kinase A

Munzuroğlu, M., Danışman, B., Akçay, G., Yelli, İ., Aslan, M., & Derin, N. (2022) · Brain Research · doi:10.1016/j.brainres.2022.148031 · Cited by 15

Levodopa responsiveness and white matter alterations in Parkinson's disease: A DTI‐based study and brain network analysis: A cross‐sectional study

Du, J., Zhou, X., Liang, Y., Zhao, L., Dai, C., Zhong, Y., Liu, H., Liu, G., Mo, L., Tan, C., et al. (2022) · Brain and Behavior · doi:10.1002/brb3.2825 · Cited by 14

Sleep Deprivation Induces Dopamine System Maladaptation and Escalated Corticotrophin-Releasing Factor Signaling in Adolescent Mice

Tuan, L., Yeh, J.-W., Lee, L. J., & Lee, L. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03258-2 · Cited by 17

Acute administration of a dopamine D2/D3 receptor agonist alters behavioral and neural parameters in adult zebrafish

Nabinger, D. D., Altenhofen, S., Buatois, A., Facciol, A., Peixoto, J. V., da Silva, J. M. K., Chatterjee, D., Rübensam, G., Gerlai, R. T., & Bonan, C. D. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110753 · Cited by 16

A new mechanistic insight into the association between environmental perfluorooctane sulfonic acid (PFOS) exposure and attention deficit and hyperactivity disorder (ADHD)-like behavior.

Zhang, M., Gu, X., Wu, L., Wan, N.-N., Liu, Y., Xin, Z., Chen, T., Liu, S., Li, M.-Q., Deng, M., et al. (2023) · Neurotoxicology · doi:10.1016/j.neuro.2023.11.004 · Cited by 14

Untargeted metabolomics reveal pathways associated with neuroprotective effect of oxyresveratrol in SH-SY5Y cells

Mahamud, N., Songvut, P., Muangnoi, C., Rodsiri, R., Dahlan, W., & Tansawat, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-47558-y · Cited by 15

Dopaminergic and serotoninergic systems as preferential targets of the pyrethroid tefluthrin exposure in the rat brain

Maximiliano, J.-E., Arés, I., Martínez, M., López-Torres, B., Martínez‐Larrañaga, M., Anadón, A., & Martínez, M. (2024) · Environmental Research · doi:10.1016/j.envres.2024.118239 · Cited by 15

Aberrant Dopamine Receptor Signaling Plays Critical Role in the Impairment of Striatal Neurons in Experimental Cerebral Malaria

Simhadri, P. K., & Babu, P. P. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02076-0 · Cited by 15

Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats

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Effects of prenatal testosterone exposure on the development of autism‐like behaviours in offspring of Wistar rats

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Nanofibrillar biochar from industrial waste as hosting network for transition metal dichalcogenides. Novel sustainable 1D/2D nanocomposites for electrochemical sensing

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Impact of distinct neurotransmitter release modes on neuronal signaling

Zhang, K. J., Monteggia, L. M., & Kavalali, E. T. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03373-7 · Cited by 22

The roles of personalized nutrition in obesity and diabetes management: a review

Zeinalian, R., Ahmadikhatir, S., Nasli‐Esfahani, E., Namazi, N., & Larijani, B. A. (2022) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-022-01016-0 · Cited by 17

Dopamine regulates astrocytic IL-6 expression and process formation via dopamine receptors and adrenoceptors

Morimoto, K., Ouchi, M., Kitano, T., Eguchi, R., & Otsuguro, K. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175110 · Cited by 13

Active vs passive novelty-related strategies: Sex differences in exploratory behaviour and monoaminergic systems

Liiver, K., Imbeault, S., Školnaja, M., Kaart, T., Kanarik, M., Laugus, K., Wettinck, J. D., Pulver, A., Shimmo, R., & Harro, J. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114297 · Cited by 14

Dopaminergic System in Promoting Recovery from General Anesthesia

Wang, J., Miao, X., Sun, Y., Li, S., Wu, A., & Wei, C. (2023) · Brain Sciences · doi:10.3390/brainsci13040538 · Cited by 14

Dendrimer─Gold Nanocomposite-Based Electrochemical Aptasensor for the Detection of Dopamine

Sipuka, D. S., Olorundare, F. O. G., Makaluza, S., Midzi, N., Sebokolodi, T. I., Arotiba, O. A., & Nkosi, D. (2023) · ACS Omega · doi:10.1021/acsomega.3c03133 · Cited by 14

Updating functional brain units: Insights far beyond Luria

Peña‐Casanova, J., Sánchez‐Benavides, G., & Sigg-Alonso, J. (2024) · Cortex · doi:10.1016/j.cortex.2024.02.004 · Cited by 16

The neurobiological effects of senescence on dopaminergic system: A comprehensive review

Rocha, G. S., Freire, M. A. M., de Paiva, K. M., Oliveira, R. F., Morais, P. L. A. D. G., dos Santos, J. R., & Cavalcanti, J. R. L. D. P. (2024) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2024.102415 · Cited by 14

Rats Lacking the Dopamine Transporter Display Inflexibility in Innate and Learned Behavior

Belskaya, A. D., Kurzina, N. P., Savchenko, A. A., Sukhanov, I., Gromova, A. A., Gainetdinov, R. R., & Volnova, A. B. (2024) · Biomedicines · doi:10.3390/biomedicines12061270 · Cited by 15

Behavioral neuroscience in zebrafish: unravelling the complexity of brain-behavior relationships

Firdous, S. M., Pal, S., Khanam, S., & Zakir, F. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03275-5 · Cited by 14

Adenylyl cyclase 2 expression and function in neurological diseases

Gray, M., Nash, K. R., & Yao, Y. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14880 · Cited by 14

Severity of inattention symptoms, experiences of being bullied, and school anxiety as mediators in the association between excessive short-form video viewing and school refusal behaviors in adolescents

Du, Y., Wang, J., Wang, Z., Liu, J., Li, S., Lv, J., Peng, Y., Chang, S., Li, M., Liu, H., et al. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1450935 · Cited by 14

Signal-On Detection of Dopamine and Tyrosinase Using Tris(hydroxypropyl)phosphine as a New Lucigenin Chemiluminescence Coreactant

Mostafa, I. M., Abdussalam, A., Liu, H., Dong, Z., Xia, S., Alboull, A. M. A., Lou, B., & Xu, G. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c00748 · Cited by 14

The development of a disposable voltammetric sensor based on two-dimensional leaf-like ZIF-L (Zn) modified screen-printed graphite electrode for the simultaneous analysis of uric acid, dopamine and theophylline

Beitollahi, H., Tajik, S., Dourandish, Z., Mohammadi, S. Z., Nejad, F. G., & Zaimbashi, R. (2024) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2024.113158 · Cited by 14

CeO2 Nanocubes as an Electrochemical Sensing Platform for Simultaneous Detection of Dopamine and Acetaminophen

Kumar, A., Ali, M., Pathak, A., Guin, D., & Tripathi, C. S. P. (2025) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/adc2a4 · Cited by 14

Differential pulse voltametric detection of dopamine using polyaniline-functionalized graphene oxide/silica nanocomposite for point-of-care diagnostics

Tejwani, A., Sonkar, U., Shrivas, K. K., Tandey, K., Karbhal, I., Deb, M. K., & Pervez, S. (2025) · RSC Advances · doi:10.1039/d5ra00714c · Cited by 14

Role of Nuclear Imaging to Understand the Neural Substrates of Brain Disorders in Laboratory Animals: Current Status and Future Prospects

D’Elia, A., Schiavi, S., Soluri, A., Massari, R., Soluri, A., & Trezza, V. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.596509 · Cited by 14

Lab-In-A-Syringe: A Novel Electrochemical Biosensor for On-Site and Real-Time Monitoring of Dopamine in Freely Behaving Mice

Alachkar, A., Alhassan, S., & Şenel, M. (2022) · ACS Sensors · doi:10.1021/acssensors.1c02525 · Cited by 14

Development of Prodrugs for Treatment of Parkinson‘s Disease: New Inorganic Scaffolds for Blood–Brain Barrier Permeation

Battista, V. D., & Hey‐Hawkins, E. (2022) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2022.02.005 · Cited by 14

Effect of Ionic Liquid Structure on the Electrochemical Response of Dopamine at Room Temperature Ionic Liquid‐modified Carbon Paste Electrodes (IL–CPE)

Hernández‐Vargas, S. G., Cevallos‐Morillo, C. A., & Aguilar, J. C. (2020) · Electroanalysis · doi:10.1002/elan.201900701 · Cited by 14

Long-lasting behavioral effects of quinpirole exposure on zebrafish

Nabinger, D. D., Altenhofen, S., Peixoto, J. V., da Silva, J. M. K., & Bonan, C. D. (2021) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2021.107034 · Cited by 14

Kraft-Based Femtosecond Laser-Induced Graphene for Electrochemical Dopamine Sensing

Gao, S., Bian, X., Bi, H., Xing, W. Q., Su, R., Liang, M., Li, T., & You, R. (2025) · Langmuir · doi:10.1021/acs.langmuir.4c04568 · Cited by 13

The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder

Guo, Q., Li, Z.-F., Hu, D., Li, P., Wu, K.-N., Fan, H.-H., Deng, J. F., Wu, H., Zhang, X., & Zhu, J. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00430-3 · Cited by 14

Dopamine: The Amazing Molecule

Genç, M. E., & Özdamar, E. N. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.95444 · Cited by 1

The physiology, signaling, and pharmacology of dopamine receptors

Beaulieu, J.-M., & Gainetdinov, R. R. (2011) · Pharmacological Reviews · doi:10.1124/pr.110.002642 · Cited by 2,763

Dopamine: the rewarding years

Marsden, C. A. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706473 · Cited by 140

Perspective Chapter: The Role of Dopamine Receptors in Neuropsychiatric Diseases

Yaman, B. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.112320 · Cited by 4

Current Concepts on the Physiopathological Relevance of Dopaminergic Receptors

Ledonne, A., & Mercuri, N. B. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00027 · Cited by 86