Cited by 399Privacy-Preserving Technologies in DataArtificial Intelligence in Healthcare and EducationInternet of Things and AI

The DOI matches its Crossref record; 241 of the 241 references it cites were found in a registry or an index; none of the 112 sources its claims cite is checked for support yet.

Federated learning-based AI approaches in smart healthcare: concepts, taxonomies, challenges and open issues

Open access

Abstract

Federated Learning (FL), Artificial Intelligence (AI), and Explainable Artificial Intelligence (XAI) are the most trending and exciting technology in the intelligent healthcare field. Traditionally, the healthcare system works based on centralized agents sharing their raw data. Therefore, huge vulnerabilities and challenges are still existing in this system. However, integrating with AI, the system would be multiple agent collaborators who are capable of communicating with their desired host efficiently. Again, FL is another interesting feature, which works decentralized manner; it maintains the communication based on a model in the preferred system without transferring the raw data. The combination of FL, AI, and XAI techniques can be capable of minimizing several limitations and challenges in the healthcare system. This paper presents a complete analysis of FL using AI for smart healthcare applications. Initially, we discuss contemporary concepts of emerging technologies such as FL, AI, XAI, and the healthcare system. We integrate and classify the FL-AI with healthcare technologies in different domains. Further, we address the existing problems, including security, privacy, stability, and reliability in the healthcare field. In addition, we guide the readers to solving strategies of healthcare using FL and AI. Finally, we address extensive research areas as well as future potential prospects regarding FL-based AI research in the healthcare management system.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

This survey reviews federated learning (FL), artificial intelligence (AI), and explainable AI (XAI) for smart healthcare, proposing taxonomies and discussing integration benefits, challenges, and future directions. It reports performance metrics from prior studies and identifies open issues in security, privacy, reliability, scalability, and dataset availability.

Key findings

  • The paper presents a comprehensive FL-AI-healthcare taxonomy and classifies applications including EHR management, remote health monitoring, biomedical image analytics, and COVID-19 detection.
  • It identifies major existing healthcare challenges—security/privacy, reliability, confidentiality, and scalability—and discusses FL, FL+AI, and FL+XAI as solution strategies.
  • Table 7 reports accuracy/AUC from reviewed works: e.g., BlockFL on Pima Indians diabetes accuracy 0.84; Naïve Bayes on Abalone 0.98 and Random Forest on Wine 0.99; FL(Lasso) AUC 0.693–0.805 across NYC hospital datasets; FL without noise (MLP) AUC 0.796–0.834; Fed-Align-CL AUC 0.70–0.84; Unet 0.94 accuracy; ST-CNN-GAP-6 0.95 accuracy and 0.99 AUC; VGG16 0.97 accuracy and AUC; Random Forest 0.919 accuracy; Random Forest 87.76 accuracy and 0.953 AUC.
  • Future directions include FL in data science, AI with blockchain for security, controlling robots using FL-AI, FL with big data analytics, FL-blockchain in Industry 5.0, and FL-blockchain for accessing medical data.

Methods

  • Design: a narrative survey/review that integrates concepts, taxonomies, motivations, challenges, and open issues for FL-based AI in smart healthcare.
  • Data or sample: no primary dataset or experiment; it analyzes existing literature and summarizes prior works in Tables 2–8, including datasets used in FL, AI, XAI, and healthcare.
  • Main analysis: conceptual and taxonomic synthesis, comparative tables of related works, and a performance-metric analysis using accuracy and AUC values extracted from previously published studies.

Limitations

  • Paper-stated: healthcare is not limited to AI and FL techniques, and various problems and challenges still need to be addressed; open issues include suitable dataset scarcity, non-IID data and outliers, expensive and time-consuming training, and unsatisfactory generalization of current ML models in the medical sector.
  • Evident from the text: the work is a survey without primary data collection, systematic review protocol, or meta-analysis, so its performance comparisons rely on heterogeneous prior studies.
  • Evident from the text: Table 7 mixes different datasets, methods, and tasks, so the reported accuracy/AUC values are not directly comparable across studies.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1007/s10586-022-03658-4

Cites

241 of 241 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

81 Not checked yet · 31 Own interpretation · 11 No basis given

Verify all 112 references — free account

Show all 31 claims

  • It may state two separate claims as one. 45
  • Probably not a substantial claim. 70
92 of 92
  • The authors state this as an assumption.

    The global model is after an assignment is completed, and the associated learning model is after data aggregation.

    “Assume the global model is after an assignment is completed, and associated learning model is after data aggregation.”
  • The authors state this as an assumption.

    There is a fiduciary physician-patient connection in eHealth.

    “Assuming that there is a fiduciary physician-patient connection in eHealth, the ethical obligations for the treatment of patient data in general and EHRs in particular that arise from the fiduciary relationship in standard health care also apply in eHealth [143].”
  • The paper relies on this without support.

    The primary criterion of FL is privacy protection.

    “However, because the primary criterion of FL is privacy protection, the aggregation model cannot be realized in practice.”
  • The paper relies on this without support.

    Healthcare data is dispersed, not in the same format, and susceptible in nature.

    “However, the data on the healthcare sector is dispersed. They are not in the same format, and the data is susceptible in nature, as it includes information from the medical industry.”
  • The paper relies on this without support.

    Insurance sector data cannot be transmitted from one sector to another.

    “The most sensitive of them are insurance sector data, which cannot be transmitted from one sector to another.”
  • The paper relies on this without support.

    Without data transfer, processing with traditional learning and training methodologies is impossible.

    “Without data transfer, processing with traditional learning and training methodologies is impossible, resulting in a significant gap in data analysis.”
  • The paper relies on this without support.

    The linking sectors are vast and data production is vast, making it difficult to identify malicious users among thousands of connected clients.

    “As the linking sectors are vast in this era, and data production is also vast, it is difficult to identify malicious users among the thousands of connected clients; therefore, by leveraging the benefits of FL, the clients’ data is preserved safely with their own model, and data leakage is prevented to avoid any malicious data modification in the system.”
  • The paper relies on this without support.

    Traditional or statistically based prediction for the medical sector is problematic with expanding amount of data because it involves human data collection.

    “Traditional or statistically based prediction for the medical sector is problematic with the expanding amount of data because it involves human data collection.”
  • The paper relies on this without support.

    There is a significant demand for automation throughout data gathering, processing, and result creation processes.

    “There is a significant demand for automation throughout the data gathering, processing, and result creation processes.”
  • The paper relies on this without support.

    A system that can receive information from multiple sources and perform a task, solve crucial problems, or make a decision without human intervention would be extremely valuable to the healthcare business.

    “Again, a system that can receive information from multiple sources and perform a task, solve crucial problems, or make a decision without human intervention would be extremely valuable to the healthcare business.”
  • The paper relies on this without support.

    Deep learning algorithms are typically black-box models, so there is no acceptable explanation for a given prediction.

    “Because deep learning algorithms are typically black-box models, there is no acceptable explanation for a given prediction.”
  • The paper relies on this without support.

    Explainability is vital in healthcare because a given prediction must be explained to persuade a clinical healthcare practitioner and a patient.

    “Explainability is vital in healthcare since we need to explain why a given prediction for sample input is made to persuade a clinical healthcare practitioner and a patient.”
  • The paper relies on this without support.

    Some deep-learning-based diagnosis jobs are even more accurate than human medical specialists.

    “Some deep-learning-based diagnosis jobs are even more accurate than human medical specialists.”
  • The paper relies on this without support.

    Artificial intelligence approaches such as deep learning with the integration of FL have recently played a revolutionary role in healthcare, particularly in terms of diagnosis and surgery.

    “Artificial intelligence approaches such as deep learning with the integration of FL have recently played a revolutionary role in healthcare, particularly in terms of diagnosis and surgery.”
  • The paper relies on this without support.

    In these fields, these strategies have been proven to be beneficial.

    “In these fields, these strategies have been proven to be beneficial.”
  • The paper relies on this without support.

    Health-related data is more susceptible to privacy and security risks than other data.

    “The health-related data is susceptible compared to the others.”
  • The paper relies on this without support.

    The performance obtained from health data is not satisfactory because the domain of the information is not the same and the data contains outliers.

    “Apart from this, the performance obtained from the health data is not satisfactory because the domain of the information is not the same and also contains outliers into the data points.”
  • The paper relies on this without support.

    Processing health data and training machine learning models is expensive and time-consuming.

    “Processing the health data and training machine learning models is expensive and time-consuming.”
  • The paper relies on this without support.

    The generalization power of current machine learning models is not satisfactory in the medical sector.

    “The generalization power of the current machine learning models is not satisfactory when it comes to the medical sector.”
  • The paper relies on this without support.

    IoT sensors have less memory.

    “the sensors that are associated with the IoT-based mechanism have less memory”
  • The paper relies on this without support.

    IoT sensors generate a massive amount of data every nanosecond.

    “They do, however, generate a massive amount of data for every nanosecond.”
  • The paper relies on this without support.

    AI applications need a secured platform to continue their activities.

    “AI applications need a secured platform to continue its activities in the applications environments.”
  • The paper relies on this without support.

    Training an agent necessitates the collection of large amounts of data from many sources, making secure data collection vital.

    “However, because training an agent necessitates the collection of large amounts of data from many sources, it is vital to provide secure data collection for training.”
  • The paper relies on this without support.

    Medical data is extremely sensitive, and any changes could result in a massive loss for the entire system.

    “However, medical data is extremely sensitive, and any changes could result in a massive loss for the entire system.”
  • The paper relies on this without support.

    There is a high demand for standardization throughout data collection, processing, and result generation processes in healthcare.

    “There is a high demand for standardization throughout the data collection, processing, and result generation processes.”
  • The paper relies on this without support.

    Healthcare is not limited to only AI and FL techniques.

    “healthcare is not limited to only AI and FL techniques”
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Self-check

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Each contradiction between two passages listed here was confirmed by an independent check.

5 of 5

Citations

Cites

1 retracted

Show all 228 references

Research works printed but not linked: 13

  1. Chakrobartty, S., El-Gayar, O.: Explainable artificial intelligence in the medical domain: A systematic review (2021)
  2. Dhuri, U., Jain, N.: Teaching assessment tool: using ai and secure techniques. Int. J. Education Manag. Eng. 6(08), 12–21 (2020)
  3. Zhou, X., Chai, C., Li, G., Sun, J.: Database meets artificial intelligence: A survey. IEEE Transactions on Knowledge and Data Engineering (2020)
  4. Pawar, U., O’Shea, D., Rea, S., O’Reilly, R.: Incorporating explainable artificial intelligence (xai) to aid the understanding of machine learning in the healthcare domain. In: AICS, pp. 169–180 (2020)
  5. Deshpande, N.M., Gite, S.S.: A brief bibliometric survey of explainable ai in medical field. Lib. Philo. Pract pp. 1–27 (2021)
  6. McMahan, B., Moore, E., Ramage, D., Hampson, S., y Arcas, B.A.: Communication-efficient learning of deep networks from decentralized data. In: Artificial intelligence and statistics, pp. 1273–1282. PMLR (2017)
  7. Smith, V., Forte, S., Chenxin, M., Takáč, M., Jordan, M.I., Jaggi, M.: Cocoa: A general framework for communication-efficient distributed optimization. J. Machine Learning Res. 18, 230 (2018)
  8. Yang, Q., Liu, Y.: Federated learning: the last on kilometer of artificial intelligence. J. Intelligent Sys. 15(1), 183–186 (2020)
  9. Li, Q., Wen, Z., Wu, Z., Hu, S., Wang, N., Li, Y., Liu, X., He, B.: A survey on federated learning systems: vision, hype and reality for data privacy and protection. arXiv preprint arXiv:1907.09693 (2019) · arXiv
  10. Muhammad, G., Hossain, M.S., Guizani, N.: Explainable ai and mass surveillance system-based healthcare framework to combat covid-19 like pandemics. IEEE Network 34(4), 126–132 (2020) · DOI · Paper page
  11. Xu, X., Peng, H., Sun, L., Bhuiyan, M.Z.A., Liu, L., He, L.: Fedmood: Federated learning on mobile health data for mood detection. arXiv preprint arXiv:2102.09342 (2021) · arXiv
  12. Vaid, A., Jaladanki, S.K., Xu, J., Teng, S., Kumar, A., Lee, S., Somani, S., Paranjpe, I., De Freitas, J.K., Wanyan, T., et al.: Federated learning of electronic health records improves mortality prediction in patients hospitalized with covid-19. medRxiv (2020) · DOI · Paper page
  13. Xianjia, Y., Queralta, J.P., Heikkonen, J., Westerlund, T.: Federated learning in robotic and autonomous systems. arXiv preprint arXiv:2104.10141 (2021) · DOI · Paper page

Cited by

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Items 101–200 of 399

Metadata

Authors
Rahman, A., Hossain, M. S., Muhammad, G., Kundu, D., Debnath, T., Rahman, M., Khan, M. S. I., Tiwari, P., & Band, S. S.
Affiliations
  • University of Dhaka (BD)
  • Mawlana Bhashani Science and Technology University (BD)
  • King Saud University (SA)
  • Aalto University (FI)
  • National Yunlin University of Science and Technology (TW)
Corresponding author
  • Muhammad, Ghulam
  • Band, Shahab S.
Venue
Cluster Computing
Published
2022-08-17
Volume
26
Issue
4
Pages
2271-2311
ISSN
  • 1386-7857 (ISSN-L)
  • 1573-7543
OpenAlex
W4292148537
Cited by
399
References
228
Citations by year
2026: 93 · 2025: 149 · 2024: 99 · 2023: 53 · 2022: 5
FWCI
25.17
Type
journal article
Language
en
Open access
Locations
  • Cluster Computing (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
King Saud University (RSP-2021/34, RSP-2021)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Privacy-Preserving Technologies in Data
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Information Systems › Internet of Things and AI
Keywords
federated learning, artificial intelligence in healthcare, explainable AI, smart healthcare, decentralized data processing, privacy preservation, healthcare security, healthcare management systems

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