Gut Microbiota and Autism Spectrum Disorder: A Neuroinflammatory Mediated Mechanism of Pathogenesis?

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Koh, A., De Vadder, F., Kovatcheva-Datchary, P., & Bäckhed, F. (2016) · Cell · doi:10.1016/j.cell.2016.05.041 · Cited by 7,070 · see citing works

Gut microbiota in human metabolic health and disease

Fan, Y., & Pedersen, O. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0433-9 · Cited by 4,724 · see citing works

Functional interactions between the gut microbiota and host metabolism

Tremaroli, V., & Bäckhed, F. (2012) · Nature · doi:10.1038/nature11552 · Cited by 4,387 · see citing works

Formation of propionate and butyrate by the human colonic microbiota

Louis, P., & Flint, H. J. (2017) · Environmental Microbiology · doi:10.1111/1462-2920.13589 · Cited by 3,028 · see citing works

The gut microbiota, bacterial metabolites and colorectal cancer

Louis, P., Hold, G. L., & Flint, H. J. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3344 · Cited by 2,836 · see citing works

Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X., Kubo, C., & Koga, Y. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.063388 · Cited by 2,735 · see citing works

The gut microbiota–brain axis in behaviour and brain disorders

Morais, L. H., Schreiber, H. L., & Mazmanian, S. K. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-00460-0 · Cited by 2,149 · see citing works

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

Elinav, E., Strowig, T., Kau, A. L., Henao-Mejia, J., Thaiss, C. A., Booth, C. J., Peaper, D. R., Bertin, J., Eisenbarth, S. C., Gordon, J. I., et al. (2011) · Cell · doi:10.1016/j.cell.2011.04.022 · Cited by 2,024 · see citing works

Functions of S100 Proteins

Donato, R., Cannon, B. R., Sorci, G., Riuzzi, F., Hsu, K., Weber, D. J., & Geczy, C. L. (2012) · Current Molecular Medicine · doi:10.2174/156652413804486214 · Cited by 1,319 · see citing works

Psychobiotics: A novel class of psychotropic

Dinan, T. G., Stanton, C., & Cryan, J. F. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.05.001 · Cited by 1,287 · see citing works

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Sharon, G., Cruz, N. J., Kang, D.-W., Gandal, M. J., Wang, B., Kim, Y.-M., Zink, E. M., Casey, C. P., Taylor, B. C., Lane, C. J., et al. (2019) · Cell · doi:10.1016/j.cell.2019.05.004 · Cited by 1,182 · see citing works

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D., & Rubin, R. A. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-22 · Cited by 1,076 · see citing works

New evidences on the altered gut microbiota in autism spectrum disorders

Strati, F., Cavalieri, D., Albanese, D., De Felice, C., Donati, C., Hayek, J., Jousson, O., Leoncini, S., Renzi, D., Calabrò, A., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0242-1 · Cited by 1,040 · see citing works

HMGB1 in health and disease

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.05.001 · Cited by 956 · see citing works

BDNF and Activity-Dependent Synaptic Modulation: Figure 1.

Lu, B. (2003) · Learning & Memory · doi:10.1101/lm.54603 · Cited by 945 · see citing works

Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified

De Angelis, M., Piccolo, M., Vannini, L., Siragusa, S., De Giacomo, A., Serrazzanetti, D. I., Cristofori, F., Guerzoni, M. E., Gobbetti, M., & Francavilla, R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076993 · Cited by 887 · see citing works

The Gut Microbiota and Inflammation: An Overview

Bander, Z. A., Nitert, M. D., Mousa, A., & Naderpoor, N. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17207618 · Cited by 783 · see citing works

The role of short-chain fatty acids in immunity, inflammation and metabolism

Yao, Y., Cai, X. T., Fei, W., Ye, Y., Zhao, M., & Zheng, C. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1854675 · Cited by 776 · see citing works

Gastrointestinal microbiota in children with autism in Slovakia

Tomova, A., Husarova, V., Lakatosova, S., Bakos, J., Vlkova, B., Babinska, K., & Ostatnikova, D. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.10.033 · Cited by 632 · see citing works

BDNF in schizophrenia, depression and corresponding animal models

Angelucci, F., Brené, S., & Mathé, A. A. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001637 · Cited by 548 · see citing works

Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First‐degree Relatives

de Magistris, L., Familiari, V., Pascotto, A., Sapone, A., Frolli, A., Iardino, P., Carteni, M., De Rosa, M., Francavilla, R., Riegler, G., et al. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181dcc4a5 · Cited by 546 · see citing works

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

Calabrese, F., Rossetti, A. C., Racagni, G., Gass, P., Riva, M. A., & Molteni, R. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00430 · Cited by 482 · see citing works

Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis

Masi, A., Quintana, D. S., Glozier, N., Lloyd, A. R., Hickie, I. B., & Guastella, A. J. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.59 · Cited by 467 · see citing works

Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review

Zhao, M., Chu, J., Feng, S., Guo, C., Xue, B., He, K., & Li, L. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114985 · Cited by 466 · see citing works

Altered gut microbiota and short chain fatty acids in Chinese children with autism spectrum disorder

Liu, S., Li, E., Sun, Z., Fu, D., Duan, G., Jiang, M., Yu, Y., Mei, L., Yang, P., Tang, Y., et al. (2019) · Scientific Reports · doi:10.1038/s41598-018-36430-z · Cited by 457 · see citing works

Short-chain fatty acid fermentation products of the gut microbiome: implications in autism spectrum disorders

MacFabe, D. F. (2012) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v23i0.19260 · Cited by 432 · see citing works

Elevated fecal short chain fatty acid and ammonia concentrations in children with autism spectrum disorder

Wang, L., Christophersen, C. T., Sorich, M. J., Gerber, J. P., Angley, M. T., & Conlon, M. A. (2012) · Digestive Diseases and Sciences · doi:10.1007/s10620-012-2167-7 · Cited by 412 · see citing works

Differences in fecal microbial metabolites and microbiota of children with autism spectrum disorders

Kang, D.-W., Ilhan, Z. E., Isern, N. G., Hoyt, D. W., Howsmon, D. P., Shaffer, M., Lozupone, C. A., Hahn, J., Adams, J. B., & Krajmalnik-Brown, R. (2018) · Anaerobe · doi:10.1016/j.anaerobe.2017.12.007 · Cited by 381 · see citing works

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

Parker, A., Romano, S., Ansorge, R., Aboelnour, A., Le Gall, G., Savva, G. M., Pontifex, M. G., Telatin, A., Baker, D., Jones, E., et al. (2022) · Microbiome · doi:10.1186/s40168-022-01243-w · Cited by 368 · see citing works

The role of inflammation in irritable bowel syndrome (IBS)

Ng, Q. X., Soh, A. Y. S., Loke, W., Lim, D. Y., & Yeo, W. S. (2018) · Journal of Inflammation Research · doi:10.2147/jir.s174982 · Cited by 360 · see citing works

Composition of gut microbiota in children with autism spectrum disorder: a systematic review and meta-analysis

Iglesias-Vázquez, L., Van Ginkel Riba, G., Arija, V., & Canals, J. (2020) · Nutrients · doi:10.3390/nu12030792 · Cited by 352 · see citing works

Seminars in cell and developmental biology

Smyth, I., & Bertram, J. F. (2018) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2018.11.003 · Cited by 351 · see citing works

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

Hu, B., Elinav, E., Huber, S., Strowig, T., Hao, L., Hafemann, A., Jin, C., Wunderlich, C. M., Wunderlich, T., Eisenbarth, S. C., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307575110 · Cited by 325 · see citing works

Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder

Wang, Y., Li, N., Yang, J.-J., Zhao, D.-M., Chen, B., Zhang, G.-Q., Chen, S., Cao, R.-F., Yu, H., Zhao, C.-Y., et al. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104784 · Cited by 324 · see citing works

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

Virtue, A. T., McCright, S. J., Wright, J. M., Jimenez, M. T., Mowel, W. K., Kotzin, J. J., Joannas, L., Basavappa, M. G., Spencer, S. P., Clark, M. L., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aav1892 · Cited by 317 · see citing works

Inflammation and Neuro-Immune Dysregulations in Autism Spectrum Disorders

Siniscalco, D., Schultz, S. T., Brigida, A. L., & Antonucci, N. (2018) · Pharmaceuticals · doi:10.3390/ph11020056 · Cited by 306 · see citing works

Osteopontin Is a Critical Inhibitor of Calcium Oxalate Crystal Formation and Retention in Renal Tubules

Wesson, J. A., Johnson, R. J., Mazzali, M., Beshensky, A. M., Stietz, S., Giachelli, C. M., Liaw, L., Alpers, C. E., Couser, W. G., Kleinman, J. G., et al. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000040593.93815.9d · Cited by 295 · see citing works

Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1)

Durrenberger, P. F., Ettorre, A., Kamel, F. O., Webb, L. V., Sim, M. J. W., Nicholas, R. S., Malik, O., Reynolds, R., Boyton, R. J., & Altmann, D. M. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-1 · Cited by 286 · see citing works

Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.10.025 · Cited by 279 · see citing works

miR-146 and miR-155: Two Key Modulators of Immune Response and Tumor Development

Testa, U., Pelosi, E., Castelli, G., & Labbaye, C. (2017) · Non-Coding RNA · doi:10.3390/ncrna3030022 · Cited by 270 · see citing works

Neuroinflammation and Oxidative Stress in the Pathogenesis of Autism Spectrum Disorder

Usui, N., Kobayashi, H., & Shimada, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065487 · Cited by 267 · see citing works

Gut Microbiota Features in Young Children With Autism Spectrum Disorders

Coretti, L., Paparo, L., Riccio, M. P., Amato, F., Cuomo, M., Natale, A., Borrelli, L., Corrado, G., De Caro, C., Comegna, M., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03146 · Cited by 266 · see citing works

Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms

Sanctuary, M. R., Kain, J. N., Chen, S. Y., Kalanetra, K., Lemay, D. G., Rose, D. R., Yang, H. T., Tancredi, D. J., German, J. B., Slupsky, C. M., et al. (2019) · PLOS ONE · doi:10.1371/journal.pone.0210064 · Cited by 255 · see citing works

Evidence for miR‐181 involvement in neuroinflammatory responses of astrocytes

Hutchison, E. R., Kawamoto, E. M., Taub, D. D., Lal, A., Abdelmohsen, K., Zhang, Y., Wood, W. H., Lehrmann, E., Camandola, S., Becker, K. G., et al. (2013) · Glia · doi:10.1002/glia.22483 · Cited by 246 · see citing works

Cold Spring Harbor Symposia on Quantitative Biology

(1937) · PROTOPLASMA · doi:10.1007/bf01625030 · Cited by 244 · see citing works

Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model

Kratsman, N., Getselter, D., & Elliott, E. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.11.003 · Cited by 239 · see citing works

Inflammatory Cytokines: Potential Biomarkers of Immunologic Dysfunction in Autism Spectrum Disorders

Xu, N., Li, X., & Zhong, Y. (2015) · Mediators of Inflammation · doi:10.1155/2015/531518 · Cited by 223 · see citing works

The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

Maqsood, R., & Stone, T. W. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2039-1 · Cited by 223 · see citing works

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

Goyal, D., Ali, S. A., & Singh, R. K. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110112 · Cited by 205 · see citing works

Effects of Probiotic Supplementation on Gastrointestinal, Sensory and Core Symptoms in Autism Spectrum Disorders: A Randomized Controlled Trial

Santocchi, E., Guiducci, L., Prosperi, M., Calderoni, S., Gaggini, M., Apicella, F., Tancredi, R., Billeci, L., Mastromarino, P., Grossi, E., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.550593 · Cited by 198 · see citing works

The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders

Anand, N., Gorantla, V. R., & Chidambaram, S. B. (2022) · Cells · doi:10.3390/cells12010054 · Cited by 185 · see citing works

Intestinal Dysbiosis and Yeast Isolation in Stool of Subjects with Autism Spectrum Disorders

Iovene, M. R., Bombace, F., Maresca, R., Sapone, A., Iardino, P., Picardi, A., Marotta, R., Schiraldi, C., Siniscalco, D., Serra, N., et al. (2017) · Mycopathologia · doi:10.1007/s11046-016-0068-6 · Cited by 184 · see citing works

Gene and miRNA expression profiles in autism spectrum disorders

Seno, M. M. G., Hu, P., Gwadry, F. G., Pinto, D., Marshall, C. R., Casallo, G., & Scherer, S. W. (2010) · Brain Research · doi:10.1016/j.brainres.2010.09.046 · Cited by 175 · see citing works

Brain-derived neurotrophic factor and inflammation in depression: Pathogenic partners in crime?

Porter, G., & O'Connor, J. (2022) · World Journal of Psychiatry · doi:10.5498/wjp.v12.i1.77 · Cited by 167 · see citing works

Study effect of probiotics and prebiotics on treatment of OVA-LPS-induced of allergic asthma inflammation and pneumonia by regulating the TLR4/NF-kB signaling pathway

Wu, Z., Nasab, E. M., Arora, P., & Athari, S. S. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03337-3 · Cited by 157 · see citing works

Fecal S100A12 and fecal calprotectin as noninvasive markers for inflammatory bowel disease in children

Sidler, M. A., Leach, S. T., & Day, A. S. (2007) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20336 · Cited by 154 · see citing works

Probiotic and Oxytocin Combination Therapy in Patients with Autism Spectrum Disorder: A Randomized, Double-Blinded, Placebo-Controlled Pilot Trial

Kong, X.-J., Liu, J., Liu, K., Koh, M., Sherman, H., Liu, S., Tian, R., Sukijthamapan, P., Wang, J., Fong, M., et al. (2021) · Nutrients · doi:10.3390/nu13051552 · Cited by 150 · see citing works

Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis

Chen, W., Jiang, J., Gong, L., Shu, Z., Xiang, D., Zhang, X., Bi, K., & Diao, H. (2021) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01803-8 · Cited by 149 · see citing works

Microbiome and nutrition in autism spectrum disorder: Current knowledge and research needs

Berding, K., & Donovan, S. M. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw048 · Cited by 146 · see citing works

Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder

Abdelli, L. S., Samsam, A., & Naser, S. A. (2019) · Scientific Reports · doi:10.1038/s41598-019-45348-z · Cited by 145 · see citing works

Immune Endophenotypes in Children With Autism Spectrum Disorder

Careaga, M., Rogers, S. J., Hansen, R. L., Amaral, D. G., de Water, J. V., & Ashwood, P. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.08.036 · Cited by 143 · see citing works

Immune Abnormalities in Autism Spectrum Disorder—Could They Hold Promise for Causative Treatment?

Gładysz, D., Krzywdzińska, A., & Hozyasz, K. K. (2018) · Molecular Neurobiology · doi:10.1007/s12035-017-0822-x · Cited by 130 · see citing works

Exploring the wound healing, anti-inflammatory, anti-pathogenic and proteomic effects of lactic acid bacteria on keratinocytes

Brandi, J., Cheri, S., Manfredi, M., Carlo, C. D., Vanella, V. V., Federici, F., Bombiero, E., Bazaj, A., Rizzi, E., Manna, L., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-68483-4 · Cited by 127 · see citing works

Biomarkers in autism spectrum disorders: Current progress

Shen, L., Liu, X., Zhang, H., Lin, J., Feng, C., & Iqbal, J. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.12.009 · Cited by 124 · see citing works

Gut Microbiota, Inflammation, and Probiotics on Neural Development in Autism Spectrum Disorder

Doenyas, C. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.01.060 · Cited by 121 · see citing works

A Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat Brain

MacFabe, D. F., Rodríguez-Capote, K., Hoffman, J. E., Franklin, A. E., Mohammad-A, Y., Taylor, A. R., Boon, F. H., Cain, D. P., Kavaliers, M., Possmayer, F., et al. (2008) · American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology · doi:10.3844/ajbbsp.2008.146.166 · Cited by 114 · see citing works

The roles of the gut microbiota–miRNA interaction in the host pathophysiology

Li, M., Chen, W., & Wang, Y. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00234-7 · Cited by 110 · see citing works

Oral probiotic administration during pregnancy prevents autism‐related behaviors in offspring induced by maternal immune activation via anti‐inflammation in mice

Wang, X., Yang, J., Zhang, H., Yu, J., & Yao, Z. (2019) · Autism Research · doi:10.1002/aur.2079 · Cited by 107 · see citing works

Gut microbiota and Autism Spectrum Disorder: From pathogenesis to potential therapeutic perspectives

Mehra, A., Arora, G., Sahni, G., Kaur, M., Singh, H. B., Singh, B., & Kaur, S. (2022) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2022.03.001 · Cited by 106 · see citing works

Multiple inflammasome complexes are activated in autistic spectrum disorders

Saresella, M., Piancone, F., Marventano, I., Zoppis, M., Hernis, A., Zanette, M., Trabattoni, D., Chiappedi, M. A., Ghezzo, A., Canevini, M. P., et al. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.03.009 · Cited by 102 · see citing works

The Gut Microbiota, Kynurenine Pathway, and Immune System Interaction in the Development of Brain Cancer

Dehhaghi, M., Panahi, H. K. S., Heng, B., & Guillemin, G. J. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.562812 · Cited by 101 · see citing works

Dysbiotic Gut Microbiota and Dysregulation of Cytokine Profile in Children and Teens With Autism Spectrum Disorder

Cao, X., Liu, K., Liu, J., Liu, Y.-W., Li, X., Wang, H., Zhu, Y., Wang, P., Li, Z., Wen, J., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.635925 · Cited by 99 · see citing works

Intestinal Barrier Dysfunction and Microbiota–Gut–Brain Axis: Possible Implications in the Pathogenesis and Treatment of Autism Spectrum Disorder

Dargenio, V. N., Dargenio, C., Castellaneta, S., De Giacomo, A., Laguardia, M., Schettini, F., Francavilla, R., & Cristofori, F. (2023) · Nutrients · doi:10.3390/nu15071620 · Cited by 98 · see citing works

Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders

Nguyen, L. S., Fregeac, J., Bôle‐Feysot, C., Cagnard, N., Iyer, A. M., Anink, J. J., Aronica, E., Alibeu, O., Nitschké, P., & Colleaux, L. (2018) · Molecular Autism · doi:10.1186/s13229-018-0219-3 · Cited by 93 · see citing works

Osteopontin as two-sided mediator of intestinal inflammation

Heilmann, K., Hoffmann, U., Witte, E., Loddenkemper, C., Sina, C., Schreiber, S., Hayford, C., Holzlbhner, P., Wolk, K., Tchatchou, E., et al. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00428.x · Cited by 92 · see citing works

Plasma cytokine levels in children with autistic disorder and unrelated siblings

Manzardo, A. M., Henkhaus, R. S., Dhillon, S., & Butler, M. G. (2011) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2011.12.003 · Cited by 81 · see citing works

Brain-Derived Neurotrophic Factor in children with Autism Spectrum Disorder

Kasarpalkar, N. J., Kothari, S., & Dave, U. (2014) · Annals of Neurosciences · doi:10.5214/ans.0972.7531.210403 · Cited by 77 · see citing works

Inflammatory mediators drive neuroinflammation in autism spectrum disorder and cerebral palsy

Than, U. T. T., Liêm, N. T., Nguyen, H.-P., Nguyen, X., Trinh, D. P., Hoang, D. H., Nguyen, P. A. T., & Dang, V. D. (2023) · Scientific Reports · doi:10.1038/s41598-023-49902-8 · Cited by 77 · see citing works

Lipopolysaccharide-stimulated, NF-kB-, miRNA-146a- and miRNA-155-mediated molecular-genetic communication between the human gastrointestinal tract microbiome and the brain

Alexandrov, P. N., Zhai, Y., Li, W., & Lukiw, W. J. (2019) · Folia Neuropathologica · doi:10.5114/fn.2019.88449 · Cited by 73 · see citing works

HMGB1 in nervous system diseases: A common biomarker and potential therapeutic target

Mao, D., Yuan, Z., Xu, F., Han, X., & Zhao, H. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.1029891 · Cited by 70 · see citing works

A lack of association between elevated serum levels of S100B protein and autoimmunity in autistic children

AL-Ayadhi, L. Y., & Mostafa, G. A. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-54 · Cited by 68 · see citing works

Effects of therapeutic probiotics on modulation of microRNAs

Davoodvandi, A., Marzban, H., Goleij, P., Sahebkar, A., Morshedi, K., Rezaei, S., Mahjoubin‐Tehran, M., Tarrahimofrad, H., Hamblin, M. R., & Mirzaei, H. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-020-00668-w · Cited by 66 · see citing works

Alterations in plasma cytokine levels in chinese children with autism spectrum disorder

Hu, C., Xu, X., Xiong, G., Xu, Q., Zhou, B., Li, C., Qin, Q., Liu, C., Li, H., Sun, Y., et al. (2018) · Autism Research · doi:10.1002/aur.1940 · Cited by 65 · see citing works

Assessment of BDNF serum levels as a diagnostic marker in children with autism spectrum disorder

Barbosa, A. G., Pratesi, R., Paz, G. S. C., dos Santos, M. A. A. L., Uenishi, R. H., Nakano, E. Y., Gandolfi, L., & Pratesi, C. B. (2020) · Scientific Reports · doi:10.1038/s41598-020-74239-x · Cited by 65 · see citing works

Probiotics supplementation and brain-derived neurotrophic factor (BDNF): a systematic review and meta-analysis of randomized controlled trials

Dehghani, F., Abdollahi, S., Shidfar, F., Clark, C. C. T., & Soltani, S. (2022) · Nutritional Neuroscience · doi:10.1080/1028415x.2022.2110664 · Cited by 65 · see citing works

The Impact of Gut Microbiota-Derived Metabolites in Autism Spectrum Disorders

Marzal, L. N. P., Prince, N., Bajić, D., Roussin, L., Naudon, L., Rabot, S., Garssen, J., Kraneveld, A. D., & Perez‐Pardo, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221810052 · Cited by 63 · see citing works

The Effect of Osteopontin on Microglia

Yu, H., Liu, X., & Zhong, Y. (2017) · BioMed Research International · doi:10.1155/2017/1879437 · Cited by 62 · see citing works

Functional analysis of gut microbiota and immunoinflammation in children with autism spectrum disorders

Carissimi, C., Laudadio, I., Palone, F., Fulci, V., Cesi, V., Cardona, F., Alfonsi, C., Cucchiara, S., Isoldi, S., & Stronati, L. (2019) · Digestive and Liver Disease · doi:10.1016/j.dld.2019.06.006 · Cited by 62 · see citing works

A heritable profile of six miRNAs in autistic patients and mouse models

Özkul, Y., Taheri, S., Bayram, K. K., Şener, E. F., Mehmetbeyoğlu, E., Öztop, D. B., Aybuga, F., Tufan, E., Bayramov, R., Dolu, N., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-65847-8 · Cited by 62 · see citing works

The importance of interaction between MicroRNAs and gut microbiota in several pathways

Behrouzi, A., Ashrafian, F., Mazaheri, H., Lari, A., Nouri, M., Riazi‐Rad, F., Tavassol, Z. H., & Siadat, S. D. (2020) · Microbial Pathogenesis · doi:10.1016/j.micpath.2020.104200 · Cited by 59 · see citing works

Fecal Transplant and Bifidobacterium Treatments Modulate Gut Clostridium Bacteria and Rescue Social Impairment and Hippocampal BDNF Expression in a Rodent Model of Autism

Abuaish, S., Al-Otaibi, N. M., Abujamel, T. S., Alzahrani, S. A., Alotaibi, S. M., Alshawakir, Y. A., Aabed, K., & El-Ansary, A. K. (2021) · Brain Sciences · doi:10.3390/brainsci11081038 · Cited by 59 · see citing works

TNF-α mRNA is negatively regulated by microRNA-181a-5p in maturation of dendritic cells induced by high mobility group box-1 protein

Zhu, J., Wang, F., Wang, H., Dong, N., Zhu, X., Wu, Y., Wang, Y.-T., & Yao, Y.-M. (2017) · Scientific Reports · doi:10.1038/s41598-017-12492-3 · Cited by 58 · see citing works

An interplay between non-coding RNAs and gut microbiota in human health

Fardi, F., Khasraghi, L. B., Shahbakhti, N., Naseriyan, A. S., Najafi, S., Sanaaee, S., Alipourfard, I., Zamany, M., Karamipour, S., Jahani, M., et al. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110739 · Cited by 58 · see citing works

Distinct Cytokine and Chemokine Profiles in Autism Spectrum Disorders

Han, Y. M. Y., Cheung, W. K., Wong, C. K., Sze, S. L., Cheng, T. W. S., Yeung, M. K.-C., & Chan, A. S.-Y. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00011 · Cited by 55 · see citing works

Probiotic Supplementation During Human Pregnancy Affects the Gut Microbiota and Immune Status

Chen, Y., Li, Z., Tye, K. D., Luo, H., Tang, X., Liao, Y., Wang, D., Zhou, J., Yang, P., Li, Y., et al. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00254 · Cited by 54 · see citing works

Randomized Double-Blind Crossover Study for Evaluating a Probiotic Mixture on Gastrointestinal and Behavioral Symptoms of Autistic Children

Guidetti, C., Salvini, E., Viri, M., Deidda, F., Amoruso, A., Visciglia, A., Drago, L., Calgaro, M., Vitulo, N., Pane, M., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11185263 · Cited by 53 · see citing works

Therapeutic Effects of the In Vitro Cultured Human Gut Microbiota as Transplants on Altering Gut Microbiota and Improving Symptoms Associated with Autism Spectrum Disorder

Chen, K., Fu, Y., Wang, Y., Liao, L., Xu, H., Zhang, A., Zhang, J., Fan, L., Ren, J., & Fang, B. (2020) · Microbial Ecology · doi:10.1007/s00248-020-01494-w · Cited by 51 · see citing works

Probiotics and Prebiotics Alleviate Behavioral Deficits, Inflammatory Response and Gut Dysbiosis in Prenatal VPA-Induced Rodent Model of Autism

Adıgüzel, E., Çiçek, B., Ünal, G., Aydın, M. F., & Keti, D. B. (2022) · Physiology & Behavior · doi:10.1016/j.physbeh.2022.113961 · Cited by 51 · see citing works

Altered plasma levels of chemokines in autism and their association with social behaviors

Shen, Y., Ou, J., Liu, M., Shi, L., Li, Y., Xiao, L., Dong, H., Zhang, F., Xia, K., & Zhao, J. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.07.057 · Cited by 50 · see citing works

Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice

Osman, A., Mervosh, N. L., Strat, A. N., Euston, T. J., Zipursky, G., Pollak, R. M., Meckel, K. R., Tyler, S. R., Chan, K. L., Grice, A. B., et al. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.08.020 · Cited by 50 · see citing works

Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder

Schmitt, L., Smith, E. G., Pedapati, E. V., Horn, P. S., Will, M., Lamy, M., Barber, L., Trebley, J., Meyer, K., Heiman, M. L., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-30909-0 · Cited by 49 · see citing works

CCL11 (Eotaxin-1) Levels Predict Long-Term Functional Outcomes in Patients Following Ischemic Stroke

Roy-O’Reilly, M. A., Ritzel, R. M., Conway, S. E., Staff, I., Fortunato, G., & McCullough, L. D. (2017) · Translational Stroke Research · doi:10.1007/s12975-017-0545-3 · Cited by 48 · see citing works

Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis

Shahi, S. K., Ghimire, S., Lehman, P., & Mangalam, A. K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.966417 · Cited by 47 · see citing works

Gut Microbiota–MicroRNA Interactions in Intestinal Homeostasis and Cancer Development

Nikolaieva, N., Ševčíková, A., Omelka, R., Martiniaková, M., Mego, M., & Čierniková, S. (2022) · Microorganisms · doi:10.3390/microorganisms11010107 · Cited by 47 · see citing works

miRNAs as biomarkers of autism spectrum disorder: a systematic review and meta-analysis

Torres, N. G., Guzmán-Torres, K., García-Cerro, S., Pinilla, G., Baquero, C. A. C., Mora-Ochoa, H., García‐González, D., Canal‐Rivero, M., Crespo‐Facorro, B., & Ruíz-Veguilla, M. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02138-3 · Cited by 47 · see citing works

The Contribution of Inflammation to Autism Spectrum Disorders: Recent Clinical Evidence

Prata, J., Machado, A. S., von Doellinger, O., Almeida, M. I., Barbosa, M. A., Coelho, R. C., & Santos, S. G. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9554-7_29 · Cited by 46 · see citing works

Autism Spectrum Disorders: A Recent Update on Targeting Inflammatory Pathways with Natural Anti-Inflammatory Agents

Singh, R., Kisku, A., Kungumaraj, H. J., Nagaraj, V., Pal, A., Kumar, S., & Sulakhiya, K. (2023) · Biomedicines · doi:10.3390/biomedicines11010115 · Cited by 45 · see citing works

Alterations in the MicroRNA of the Blood of Autism Spectrum Disorder Patients: Effects on Epigenetic Regulation and Potential Biomarkers

Vaccaro, T. D. S., Sorrentino, J. M., Salvador, S., Veit, T. D., Souza, D. O., & Almeida, R. F. (2018) · Behavioral Sciences · doi:10.3390/bs8080075 · Cited by 44 · see citing works

Gastrointestinal symptoms have a minor impact on autism spectrum disorder and associations with gut microbiota and short-chain fatty acids

Deng, W., Wang, S., Li, F., Wang, F., Xing, Y. P., Li, Y., Lv, Y. H., Ke, H., Li, Z., Lv, P., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1000419 · Cited by 44 · see citing works

Microbiome-Gut-Mucosal-Immune-Brain Axis and Autism Spectrum Disorder (ASD): A Novel Proposal of the Role of Gut Microbiome in ASD Aetiology

De Sales-Millán, A., Aguirre-Garrido, J. F., González-Cervantes, R. M., & Velázquez-Aragón, J. A. (2023) · doi:10.20944/preprints202305.1223.v1 · Cited by 44 · see citing works

No evidence for a clear link between active intestinal inflammation and autism based on analyses of faecal calprotectin and rectal nitric oxide

Fernell, E., Fagerberg, U. L., & Hellström, P. M. (2007) · Acta Paediatrica · doi:10.1111/j.1651-2227.2007.00298.x · Cited by 43 · see citing works

Specificity of gut microbiota in children with autism spectrum disorder in Slovakia and its correlation with astrocytes activity marker and specific behavioural patterns

Tomova, A., Šoltýs, K., Repiská, G., Pálková, L., Filcikova, D., Minárik, G., Turna, J., Prochotska, K., Babinská, K., & Ostatníková, D. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112745 · Cited by 41 · see citing works

Functional contribution of the intestinal microbiome in autism spectrum disorder, attention deficit hyperactivity disorder, and Rett syndrome: a systematic review of pediatric and adult studies

Caputi, V., Hill, L., Figueiredo, M., Popov, J., Hartung, E., Margolis, K. G., Baskaran, K., Joharapurkar, P., Moshkovich, M., & Pai, N. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1341656 · Cited by 41 · see citing works

Increased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism Spectrum Disorders (ASDs)

Russo, A. J. (2014) · Journal of Central Nervous System Disease · doi:10.4137/jcnsd.s13767 · Cited by 40 · see citing works

Evaluation of serum Neuron‐specific enolase, S100B, myelin basic protein and glial fibrilliary acidic protein as brain specific proteins in children with autism spectrum disorder

Esnafoğlu, E., Ayyıldız, S. N., Cırrık, S., Ertürk, E. Y., Erdil, A., Dağlı, A., & Noyan, T. (2017) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2017.06.011 · Cited by 40 · see citing works

Increased serum osteopontin levels in autistic children: relation to the disease severity.

Al-Ayadhi, L., & Mostafa, G. (2011) · Brain, behavior, and immunity · doi:10.1016/j.bbi.2011.04.006 · Cited by 39 · see citing works

Decoding microRNAs in autism spectrum disorder

Li, J., Xu, X., Liu, J., Zhang, S., Tan, X., Li, Z., Zhang, J., & Wang, Z. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.11.005 · Cited by 38 · see citing works

Maladaptive Behavior and Gastrointestinal Disorders in Children with Autism Spectrum Disorder

Pusponegoro, H. D., Ismael, S., Sastroasmoro, S., Firmansyah, A., & Vandenplas, Y. (2015) · Pediatric Gastroenterology Hepatology & Nutrition · doi:10.5223/pghn.2015.18.4.230 · Cited by 36 · see citing works

mTOR Signaling Pathway Regulates the Release of Proinflammatory Molecule CCL5 Implicated in the Pathogenesis of Autism Spectrum Disorder

Wang, B., Qin, Y., Wu, Q., Li, X., Xie, D., Zhao, Z., & Duan, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.818518 · Cited by 36 · see citing works

Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition

Wang, X., Sun, Z., Yang, T., Lin, F. H., Ye, S., Yan, J., Li, T., & Chen, J. (2023) · mSystems · doi:10.1128/msystems.00415-23 · Cited by 36 · see citing works

Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults

Lopes, K. D. P., Yu, L., Shen, X., Qiu, Y., Tasaki, S., Iatrou, A., Beeri, M. S., Seyfried, N. T., Menon, V., Wang, Y., et al. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13474 · Cited by 36 · see citing works

Potential Cytokine Biomarkers in Autism Spectrum Disorders

Rose, D. R., & Ashwood, P. (2014) · Biomarkers in Medicine · doi:10.2217/bmm.14.39 · Cited by 35 · see citing works

Altered Cytokine and BDNF Levels in Individuals with Autism Spectrum Disorders

Han, Y. M. Y., Yau, S., Chan, M. M. Y., Wong, C. K., & Chan, A. S.-Y. (2022) · Brain Sciences · doi:10.3390/brainsci12040460 · Cited by 34 · see citing works

Increased serum levels of high mobility group box 1 protein in patients with autistic disorder

Emanuele, E., Boso, M., Brondino, N., Pietra, S., Barale, F., Nemi, S. U. D., & Politi, P. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.03.020 · Cited by 33 · see citing works

Autism Spectrum Disorder and miRNA: An Overview of Experimental Models

Schepici, G., Cavalli, E., Bramanti, P., & Mazzon, E. (2019) · Brain Sciences · doi:10.3390/brainsci9100265 · Cited by 33 · see citing works

Lactobacillus rhamnosus and Lactobacillus delbrueckii ameliorate the expression of miR-155 and miR-181a in SLE patients

Vahidi, Z., Samadi, M., Mahmoudi, M., Rezaieyazdi, Z., Sahebari, M., Tabasi, N. S., Esmaeili, S., Sahebkar, A., & Rastin, M. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.07.025 · Cited by 32 · see citing works

de novo Blood Biomarkers in Autism: Autoantibodies against Neuronal and Glial Proteins

Abou-Donia, M. B., Suliman, H. B., Siniscalco, D., Antonucci, N., Elkafrawy, P., & Brahmajothi, M. V. (2019) · Behavioral Sciences · doi:10.3390/bs9050047 · Cited by 32 · see citing works

Analysis of Faecal Microbiota and Small ncRNAs in Autism: Detection of miRNAs and piRNAs with Possible Implications in Host–Gut Microbiota Cross-Talk

Chiappori, F., Cupaioli, F. A., Consiglio, A., Nanni, N. D., Mosca, E., Licciulli, F., & Mezzelani, A. (2022) · Nutrients · doi:10.3390/nu14071340 · Cited by 32 · see citing works

High Serum Levels of Serum 100 Beta Protein, Neuron-specific Enolase, Tau, Active Caspase-3, M30 and M65 in Children with Autism Spectrum Disorders

Ayaydın, H., Kirmit, A., Çelık, H., Akaltun, İ., Koyuncu, İ., & Ulgar, Ş. B. (2020) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2020.18.2.270 · Cited by 31 · see citing works

Biological Psychiatry, 2nd ed.

Janicak, P. G. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.4.568a · Cited by 29 · see citing works

Fecal Short-Chain Fatty Acids Levels Were Not Associated With Autism Spectrum Disorders in Chinese Children: A Case–Control Study

Wang, J., Pan, J., Chen, H., Li, Y., Amakye, W. K., Liang, J., Ma, B., Chu, X., Mao, L., & Zhang, Z. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01216 · Cited by 29 · see citing works

Maternal treatment with sodium butyrate reduces the development of autism-like traits in mice offspring

Cristiano, C., Hoxha, E., Lippiello, P., Balbo, I., Russo, R., Tempia, F., & Miniaci, M. C. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113870 · Cited by 29 · see citing works

microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice

Zhao, W., Spiers, J. G., Vassileff, N., Khadka, A., Jaehne, E. J., van den Buuse, M., & Hill, A. F. (2023) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2023.103820 · Cited by 29 · see citing works

Decreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism

Russo, A. J. (2013) · Biomarker Insights · doi:10.4137/bmi.s11270 · Cited by 27 · see citing works

Fecal Calprotectin Levels Correlate With Main Domains of the Autism Diagnostic Interview-Revised (ADI-R) in a Sample of Individuals With Autism Spectrum Disorders From Slovakia

Babinská, K., Tomova, A., Celušáková, H., Babková, J., Repiská, G., Kubranská, A., Filcikova, D., Siklenkova, L., & Ostatníková, D. (2017) · Physiological Research · doi:10.33549/physiolres.933801 · Cited by 27 · see citing works

Involvement of CD45 cells in the development of autism spectrum disorder through dysregulation of granulocyte-macrophage colony-stimulating factor, key inflammatory cytokines, and transcription factors

Ahmad, S. F., Ansari, M. A., Nadeem, A., Bakheet, S. A., AL-Ayadhi, L. Y., Alasmari, A. F., Alanazi, M. M., Al‐Mazroua, H. A., & Attia, S. M. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106466 · Cited by 26 · see citing works

Fecal microbiota transplantation as tool to study the interrelation between microbiota composition and miRNA expression

Wortelboer, K., Bakker, G. J., Winkelmeijer, M., van Riel, N. A. W., Levin, E., Nieuwdorp, M., Herrema, H., & Davids, M. (2022) · Microbiological Research · doi:10.1016/j.micres.2022.126972 · Cited by 25 · see citing works

Age and severity-dependent gut microbiota alterations in Tunisian children with autism spectrum disorder

Chamtouri, M., Gaddour, N., Merghni, A., Mastouri, M., Arboleya, S., & Reyes‐Gavilán, C. G. D. L. (2023) · Scientific Reports · doi:10.1038/s41598-023-45534-0 · Cited by 25 · see citing works

Maternal separation stress through triggering of the neuro‐immune response in the hippocampus induces autistic‐like behaviors in male mice

Reisi‐Vanani, V., Lorigooini, Z., Bijad, E., & Amini-Khoei, H. (2023) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10310 · Cited by 25 · see citing works

MicroRNA-mediated epigenetic regulation of inflammasomes in inflammatory responses and immunopathologies

Yi, Y. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.11.006 · Cited by 23 · see citing works

MicroRNA Expression Profiles in Autism Spectrum Disorder: Role for miR-181 in Immunomodulation

Frye, R. E., Rose, S., McCullough, S. S., Bennuri, S. C., Porter-Gill, P. A., Dweep, H., & Gill, P. S. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11090922 · Cited by 22 · see citing works

The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder

Farmer, C., Thurm, A. E., Honnekeri, B., Kim, P., Swedo, S. E., & Han, J. C. (2021) · Scientific Reports · doi:10.1038/s41598-021-97367-4 · Cited by 22 · see citing works

Are Fecal Metabolome and Microbiota Profiles Correlated with Autism Severity? A Cross-Sectional Study on ASD Preschoolers

Laghi, L., Mastromarino, P., Prosperi, M., Morales, M. A., Calderoni, S., Santocchi, E., Muratori, F., & Guiducci, L. (2021) · Metabolites · doi:10.3390/metabo11100654 · Cited by 22 · see citing works

Increased Plasma Levels of the High Mobility Group Box 1 Protein (HMGB1) Are Associated With a Higher Score of Gastrointestinal Dysfunction in Individuals With Autism

Babinská, K., Bucová, M., Ďurmanová, V., Lakatošová, S., Jánošíková, D., Bakoš, J., Hlavatá, A., & Ostatníková, D. (2014) · Physiological Research · doi:10.33549/physiolres.932932 · Cited by 20 · see citing works

Plasma Levels of Glial Cell Marker S100B in Children With Autism

Tomova, A., Keményová, P., Filcikova, D., Szapuova, Z. J., Kováč, A., Babinská, K., & Ostatníková, D. (2019) · Physiological Research · doi:10.33549/physiolres.934350 · Cited by 19 · see citing works

The progress of chemokines and chemokine receptors in autism spectrum disorders

Ye, J.-R., Wang, H., Cui, L., Chu, S., & Chen, N. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.05.024 · Cited by 19 · see citing works

Gastrointestinal manifestations and their relation to faecal calprotectin in children with autism

Azouz, H. G., Zakaria, N. H., Khalil, A. F., Naguib, S. M., & Khalil, M. (2021) · Gastroenterology Review · doi:10.5114/pg.2021.111420 · Cited by 19 · see citing works

Granulocyte-macrophage colony-stimulating factor protects mice against hepatocellular carcinoma by ameliorating intestinal dysbiosis and attenuating inflammation

Wu, Y.-N., Zhang, L., Chen, T., Li, X., He, L., & Liu, G. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i36.5420 · Cited by 18 · see citing works

Increased Serum Concentrations of High Mobility Group Box 1 (HMGB1) Protein in Children with Autism Spectrum Disorder

Makris, G., Chouliaras, G. L., Apostolakou, F., Papageorgiou, C., Chrousos, G. P., Papassotiriou, I., & Pervanidou, P. (2021) · Children · doi:10.3390/children8060478 · Cited by 18 · see citing works

Global trends in research on miRNA–microbiome interaction from 2011 to 2021: A bibliometric analysis

Yan, X., Yao, J., Li, Y., Zhang, W., Xi, M., Chen, M., & Li, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.974741 · Cited by 18 · see citing works

Biomarker prediction in autism spectrum disorder using a network-based approach

Rastegari, M., Salehi, N., & Zare‐Mirakabad, F. (2023) · BMC Medical Genomics · doi:10.1186/s12920-023-01439-5 · Cited by 18 · see citing works

Microbiota in organ transplantation: An immunological and therapeutic conundrum?

Dery, K. J., Kadono, K., Hirao, H., Górski, A., & Kupiec‐Weglinski, J. W. (2020) · Cellular Immunology · doi:10.1016/j.cellimm.2020.104080 · Cited by 17 · see citing works

Fungi

Alookaran, J., Liu, Y., Auchtung, T. A., Tahanan, A., Hessabi, M., Asgarisabet, P., Rahbar, M. H., Fatheree, N. Y., Pearson, D. A., Mansour, R., et al. (2021) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000003349 · Cited by 16 · see citing works

Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner

Chen, J., Zeng, P., Gong, L., Zhang, X., Ling, Z., Bi, K., Shi, F., Wang, K., Zhang, Q., Jiang, J., et al. (2022) · mBio · doi:10.1128/mbio.02531-22 · Cited by 15 · see citing works

S100B Affects Gut Microbiota Biodiversity

Spica, V. R., Valeriani, F., Orsini, M., Clementi, M. E., Seguella, L., Gianfranceschi, G., Liddo, R. D., Sante, G. D., Ubaldi, F., Ria, F., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032248 · Cited by 15 · see citing works

A potent and selective CXCR2 antagonist improves neuroimmune dysregulation through the inhibition of NF-κB and notch inflammatory signaling in the BTBR mouse model of autism

Alomar, H. A., Ansari, M. A., Nadeem, A., Attia, S. M., Bakheet, S. A., Al‐Mazroua, H. A., Hussein, M. H., Alqarni, S. A., & Ahmad, S. F. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578069 · Cited by 15 · see citing works

Increased expression of BDNF mRNA in the frontal cortex of autistic patients

Maussion, G., Moalic, J., Simonneau, M., Gorwood, P. A. P. M., & Ramoz, N. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.06.023 · Cited by 14 · see citing works

Supplementation of Lactobacillus Probiotic Strains Supports Gut- Brain-Axis and Defends Autistic Deficits Occurred by Valproic Acid-Induced Prenatal Model of Autism

Katta, S., Mohan, G. K., & Bakshi, V. (2020) · Pharmacognosy Journal · doi:10.5530/pj.2020.12.226 · Cited by 14 · see citing works

EVALUATION OF BLOOD ZONULIN LEVELS, INFLAMMATORY PROCESSES AND NEURONAL CHANGES IN CHILDREN WITH AUTISM SPECTRUM DISORDER

Kartalcı, G., Demir, A. Ç., Kartalcı, Ş., Üremiş, N., & Türköz, Y. (2022) · Psychiatria Danubina · doi:10.24869/psyd.2022.279 · Cited by 14 · see citing works

Preliminary Findings of Elevated Inflammatory Plasma Cytokines in Children with Autism Who Have Co-Morbid Gastrointestinal Symptoms

Ashwood, P. (2023) · Biomedicines · doi:10.3390/biomedicines11020436 · Cited by 14 · see citing works

The Role of the Gut Microbiota and the Immune System in the Development of Autism

Lungba, R. M., Khan, S. Z. A., Ajibawo-Aganbi, U., Bastidas, M. V. P., Veliginti, S., Saleem, S., & Cancarevic, I. (2020) · Cureus · doi:10.7759/cureus.11226 · Cited by 13 · see citing works

Gut Microbiota Dysbiosis Aggravates Mycoplasma gallisepticum Colonization in the Chicken Lung

Wang, J., Chen, X., Li, J., & Ishfaq, M. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.788811 · Cited by 12 · see citing works

MicroRNA sensing and regulating microbiota-host crosstalk via diet motivation

Fan, Y., Qin, M., Zhu, J., Chen, X., Luo, J., Chen, T., Sun, J., Zhang, Y., & Xi, Q. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2139220 · Cited by 12 · see citing works

Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines

Takada, R., Toritsuka, M., Yamauchi, T., Ishida, R., Kayashima, Y., Nishi, Y., Ishikawa, M., Yamamuro, K., Ikehara, M., Komori, T., et al. (2024) · Molecular Autism · doi:10.1186/s13229-024-00589-2 · Cited by 12 · see citing works

Regulation of Gene Expression through Gut Microbiota-Dependent DNA Methylation in Colonic Epithelial Cells

Takahashi, K., Sugi, Y., Nakano, K., Kobayakawa, T., Nakanishi, Y., Tsuda, M., Hosono, A., & Kaminogawa, S. (2020) · ImmunoHorizons · doi:10.4049/immunohorizons.1900086 · Cited by 11 · see citing works

Host fecal DNA specific methylation signatures mark gut dysbiosis and inflammation in children affected by autism spectrum disorder

Cuomo, M., Coretti, L., Costabile, D., Monica, R. D., Riso, G. D., Buonaiuto, M., Trio, F., Bravaccio, C., Visconti, R., Canani, R. B., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-45132-0 · Cited by 11 · see citing works

From Data to Insights: Machine Learning Empowers Prognostic Biomarker Prediction in Autism

Mehmetbeyoğlu, E., Duman, A., Taheri, S., Özkul, Y., & Rassoulzadegan, M. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13121713 · Cited by 10 · see citing works

Serum brain-derived neurotrophic factor concentration is different between autism spectrum disorders and intellectual disability children and adolescents

Cui, T., Liu, Z., Li, Z., Han, Y., Xiong, W., Qu, Z., & Zhang, X. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.01.001 · Cited by 9 · see citing works

HMGB1 mediates microbiome-immune axis dysregulation underlying reduced neutralization capacity in obesity-related post-acute sequelae of SARS-CoV-2

Rubas, N. C., Peres, R., Kunihiro, B. P., Allan, N. P., Phankitnirundorn, K., Wells, R. K., McCracken, T., Lee, R. H., Umeda, L., Conching, A., et al. (2024) · Scientific Reports · doi:10.1038/s41598-023-50027-1 · Cited by 8 · see citing works

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Pan, M., Roe, J. M., Nudel, R., Schork, A. J., Iakunchykova, O. P., Fjell, A. M., Walhovd, K. B., Werge, T. M., Chen, C., Benros, M. E., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02478-3 · Cited by 7 · see citing works

Comparison of HMGB1, RAGE, TLR4, and NF-κB levels in children and adolescents diagnosed with autism spectrum disorder with healthy controls

Kıyat, E., Aktepe, E., Doğuç, D. K., Bedir, M., Ertürk, E., & Işık, Ü. (2024) · International Journal of Developmental Disabilities · doi:10.1080/20473869.2023.2301185 · Cited by 7 · see citing works

Assessment of brain-derived neurotrophic factor levels in serum of children with autism spectrum disorders

Elhamid, S. A. A., Alkherkhisy, M. M., & Kasem, R. E. (2024) · Middle East Current Psychiatry · doi:10.1186/s43045-024-00403-y · Cited by 7 · see citing works

Fungi: Friend or Foe? A Mycobiome Evaluation in Children With Autism and Gastrointestinal Symptoms

Alookaran, J. J., Liu, Y., Auchtung, T. A., Tahanan, A., Hessabi, M., Asgarisabet, P., Rahbar, M. H., Fatheree, N. Y., Pearson, D. A., Mansour, R., et al. (2022) · Digital Commons-TMC (Texas Medical Center) · Cited by 6 · see citing works

Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient micePreprint

Osman, A., Mervosh, N. L., Strat, A. N., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.29.065821 · Cited by 5 · see citing works

The Gut–Brain–Microbiota Connection and Its Role in Autism Spectrum Disorders

Młynarska, E., Barszcz, E., Budny, E., Gajewska, A., Kopeć, K., Wasiak, J., Rysz, J., & Franczyk, B. (2025) · Nutrients · doi:10.3390/nu17071135 · Cited by 44 · see citing works

CRISPR-Assisted Probiotic and In Situ Engineering of Gut Microbiota: A Prospect to Modification of Metabolic Disorders

Rahmati, R., Zarimeidani, F., Boroujeni, M. R. G., Sadighbathi, S., Kashaniasl, Z., Saleh, M., & Alipourfard, I. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10561-y · Cited by 32 · see citing works

Role of the microbiota in inflammation-related related psychiatric disorders

Zhou, L., Wu, Q. J., Jiang, L., Rao, J., Gao, J., Zhao, F., & Wang, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1613027 · Cited by 30 · see citing works

The Role of Nutrition, Oxidative Stress, and Trace Elements in the Pathophysiology of Autism Spectrum Disorders

Długosz, A., Wróblewski, M., Błaszak, B., & Szulc, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020808 · Cited by 29 · see citing works

Mechanistic Links Between Gut Dysbiosis, Insulin Resistance, and Autism Spectrum Disorder

Guevara‐Ramírez, P., Tamayo‐Trujillo, R., Ruiz‐Pozo, V. A., Cadena-Ullauri, S., Paz‐Cruz, E., & Zambrano, A. K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136537 · Cited by 20 · see citing works

Anti-Inflammatory Diet and Probiotic Supplementation as Strategies to Modulate Immune Dysregulation in Autism Spectrum Disorder

Galvis, C. A. N., Trejos-Gallego, D. M., Correa-Salazar, C., Triviño-Valencia, J., Buitrago, M. V., Ruiz-Pulecio, A. F., Méndez-Ramírez, L. F., Zabaleta, J., Meñaca-Puentes, M. A., Villa, C. A. R., et al. (2025) · Nutrients · doi:10.3390/nu17162664 · Cited by 13 · see citing works

Gut microbiota diversity and composition in children with autism spectrum disorder: associations with symptom severity

Zeng, Q., Hu, Y., Xie, L., Zhang, X., Huang, Y., Ye, J., Wang, S., & Xu, J. X. (2025) · PeerJ · doi:10.7717/peerj.19528 · Cited by 10 · see citing works

Probiotics as a Complementary Medicine in Neurologic Disorders

Jafari, M., Alipour, M., Zamani, S., Amiri, A. M., Pourabbas, P., & Bibalan, M. H. (2025) · Health Science Reports · doi:10.1002/hsr2.71422 · Cited by 11 · see citing works

Importance of Fecal Microbiota Transplantation and Molecular Regulation as Therapeutic Strategies in Inflammatory Bowel Diseases

Brusnic, O., Boicean, A., Fleacă, R. S., GRAMA, B. G., Sofonea, F., Roman-Filip, C., Roman-Filip, I., Solomon, A., Bîrsan, S., Dura, H., et al. (2024) · Nutrients · doi:10.3390/nu16244411 · Cited by 10 · see citing works

Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism

Zhang, Y., Li, H., Li, B., Li, Y., Chai, X., Li, S., Xia, X., Li, H., Zhao, Y., Tang, Y., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1535451 · Cited by 7 · see citing works

Efficacy of gut microbiota-based therapy for autism Spectrum Disorder and attention Deficit Hyperactivity Disorder: a systematic review and meta-analysis

Sun, W., Ma, L., Feng, X., Fan, Y., Cai, Y., & Li, X. (2025) · Psychology Health & Medicine · doi:10.1080/13548506.2025.2565181 · Cited by 8 · see citing works

Gut dysbiosis in neurodevelopmental disorders: linking microbiota signatures to cognitive rigidity in autism spectrum disorder

Sivamaruthi, B. S., Kesika, P., Chaiyasut, C., & Varman, D. R. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1760635 · Cited by 6 · see citing works

Biomarkers for autism spectrum disorder: a short review

Barbosa, M. G. D. S., de Souza, R. L. V., Cherain, L. G. G., Ferreira, L. H. S., Peixoto, M. E. S. A., Passos, M. L., Piza, L. M., Carneiro, R. A., Rabelo, N. N., & Chaurasia, B. K. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000002689 · Cited by 5 · see citing works

Applications and potential mechanisms of transcranial magnetic stimulation in autism spectrum disorders

Liao, X., Li, H., Han, K., Long, J., Liu, Y., Tang, Z., Chen, J., Liu, H., & Zhang, H. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07754-6 · Cited by 4 · see citing works

Decoding the gut microbiota-immune dialogue: from bidirectional axis to therapeutic applications

Liu, Y., Chen, C., Liu, H., Wang, W., Zhou, X., Guo, M., Zhao, J., Zeng, Z., & Xu, L. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04376-4 · Cited by 4 · see citing works

Multiomics analysis reveals the exacerbating effect of constipation on autism-related symptoms in children with autism spectrum disorder

Li, H. B., Li, X., Wang, X., Lin, L., Cao, M., Pan, S., Ou, X., Gu, T., Shen, S., Li, H. B., et al. (2026) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00894-5 · Cited by 5 · see citing works

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Hacıoğlu, Ö. (2026) · Progress in molecular and subcellular biology · doi:10.1007/978-3-032-11438-9_9 · Cited by 3 · see citing works

Faecal microbiota transplantation as a novel approach for autism-associated anxiety: A critical therapeutic appraisal

Malode, T. D., Chandurkar, P. A., Taksande, B. G., Tatode, A., Qutub, M., Premchandani, T., Umekar, M. J., & Taksande, J. (2025) · Medicine in Microecology · doi:10.1016/j.medmic.2025.100138 · Cited by 3 · see citing works

Oxidative Stress and Low-Grade Endotoxemia in Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): Insights from a Cross-Sectional Study

Totè, C. M., Capponi, M., Salvatori, F., Zicari, A. M., Guido, C. A., Brindisi, G., Iantorno, L., Bartimoccia, S., Baratta, F., Forte, M., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136336 · Cited by 2 · see citing works

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Mishra, A. P., Marrelli, L. M., Bonner-Reid, F. T., Shekhawat, P., Toney, R., Benipal, I. K., Dias, H. A., Kandi, A., & Siddiqui, H. F. (2025) · Cureus · doi:10.7759/cureus.88579 · Cited by 1 · see citing works

Fundus Peripapillary Vascular Changes in Autism Spectrum Disorder: A Cross‐Sectional Study

Wang, Y., Wang, Y., Zhu, Z., Xia, Z., Wang, N., Li, M., Jiao, Z., Pan, N., Zhang, Y., Chen, Q., et al. (2025) · Autism Research · doi:10.1002/aur.70094 · Cited by 1 · see citing works

Microbiota-gut-brain axis and neuroendocrine pathways underlie divergent mechanisms of intermittent and continuous theta-burst stimulation in autism spectrum disorder

Long, J., Liao, X., Han, K., Chen, J., Tang, Z., Wang, W., Wang, X., Qianqian, C., Zhang, X., & Zhang, H. (2026) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-026-06096-2 · Cited by 2 · see citing works

Serum calprotectin levels and other inflammation biomarkers in manic episode of bipolar disorder: A comparative study

Ayhan, M. G., INANLI, I., & Erdal, H. (2026) · Journal of Investigative Medicine · doi:10.1177/10815589261448844 · Cited by 1 · see citing works

Neuronutrition in ASD: Involvement of gut microbiota, oxidative stress and inflammatory markers

Avolio, E., Olivito, I., Minervini, D., Soda, T., Bartolo, A. D., Rocca, C., Alò, R., & Facciolo, R. M. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106775 · Cited by 1 · see citing works

A Developmental Neuroimmune Cascade Model of Autism Spectrum Disorder

Leisman, G., Melillo, R. J., & Alfasi, R. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27125185 · Cited by 1 · see citing works

FATORES ASSOCIADOS AO ESTADO NUTRICIONAL EM CRIANÇAS E ADOLESCENTES COM TRANSTORNO DO ESPECTRO AUTISTA

Anjos, C. M. D., Santos, T. D. O. C. G., Moraes, Y. D. F. B. D. O., Costa, S. V., Fernandez, R. D., de Oliveira, V. V., Maciel, M. J. D. S., & Pereira, D. Q. (2025) · Revista Multidisciplinar do Nordeste Mineiro · doi:10.61164/rmnm.v8i1.3805

Gut–Brain axis in neurological diseases

Roy, A., Chauhan, K., Parkash, J., Yadav, M., & Iyer, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-29932-2.00002-5

Biomarkers in Autism Spectrum Disorder: From Traditional Constraints to AI-Driven Horizons in Precision Medicine

Şahin, B., & Osmanlı, C. Ç. (2025) · European Journal of Therapeutics · doi:10.58600/eurjther2832

Insights on gut microbiota in autism spectrum disorder: a review

Adhikary, S., Rajak, P., Ganguly, A., & Bhattacharya, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27622-4.00023-7

Gut Microbiota and Mitochondrial Dysfunction in Autism: Clinical Correlations and Future Directions

Bhalla, S., & Srivastava, R. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05702-5

Gut Microbial Alteration in Pediatric Autism Spectrum Disorder Based on 16S rRNA Sequence Analysis

Zou, Y., Zou, Q., & Huang, G. (2026) · Current Bioinformatics · doi:10.2174/0115748936421910251128193659

Perinatal exposure to gaseous pollutants and autism spectrum disorder in children: A nested case–control study in the nurses’ health study ii cohort

Choi, H. M., Cardona, B., Kioumourtzoglou, M. A., Laden, F., Hart, J. E., & Weisskopf, M. G. (2026) · Environmental Science and Pollution Research · doi:10.1007/s11356-026-37583-5

Integrating genomics with the gut-brain axis: current evidence in autism spectrum disorder, epilepsy, schizophrenia, and emerging future challenges

Loza-López, E. C., Cano-Herrera, G., Gonzalez, M. F. B., Vionet, A. M., van Tienhoven, X. A., Aldaba, E. S., Argüelles, E. D. J. G., Pérez, R. M., Pérez, P. C. M., Vela, D. D. L., et al. (2026) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2026.1004146

The Microbiome-Body Connection: Unraveling the Gut-Brain Axis

Islam, M. M., Mahbub, N. U., & Islam, M. A. (2026) · Springer eBooks · doi:10.1007/978-981-95-7494-0_1

The Role of Inflammation in the Brain: A Gut-Driven Phenomenon

Mahbub, N. U., Islam, M. M., & Hong, S. T. (2026) · Springer eBooks · doi:10.1007/978-981-95-7494-0_9

Microbial dial: How the gut microbiome tunes the severity of autism spectrum disorder

Nagamine, T. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.116755

Longitudinal Adaptive Functioning Outcomes in Children with Autism Spectrum Disorder During a 180 Day Open-Label Extension of K11-Tmax, a Consortium Probiotic Mix with Multivitamins

Guimaraes, D. O., Silva, R. S., Ferreira, L. A., Martinelli, L., Werly, R. M. M., Amorim, R. F., Holzbach, L. B. S. S., Badaró, R. J. S., Santos, A. A. B., Vasquez, E. C., et al. (2026) · Life · doi:10.3390/life16060940

Immune-related mechanisms of fecal microbiota transplantation in the intestinal microenvironment as a potential intervention for autism spectrum disorder patients

de Azevedo, O. G. R., de Vasconcelos, P. R. L., Rosa, P. N. S., Ciurleo, G. C. V., Warren, C. A., & Oriá, R. B. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1775104

Altered Stool Cytokine Profiles and Pro-Inflammatory/Anti-Inflammatory Imbalance in Children with Autism Spectrum Disorder: A Developmental Analysis

Finderle, P., Vrhovšek, M. J., Zmrzljak, U. P., Osredkar, D., Avguštin, G., & Osredkar, J. (2026) · Biomedicines · doi:10.3390/biomedicines14071559

Clinical Improvement and Taxonomic–Functional Gut Microbiome Remodeling After Six Months of Multi-Strain Synbiotic Supplementation in Mexican Children with Autism Spectrum Disorder

Sales-Millán, A. D., Reyes-Ferreira, P., González‐Cervantes, R. M., Luna-Alvarez, M., López, S. G., Cobo-Díaz, J. F., Ramos, S., Garrido, J. F. A., & Velázquez-Aragón, J. A. (2026) · Nutrients · doi:10.3390/nu18152441

Neuroinflammatory Response to Postnatal Administration of Valproic Acid in Wistar Rats as a Mechanism for the Development of Autism Spectrum Disorders: The Role of Neutrophils

Стаханова, А. А., Zozulya, S. A., Kost, N., VOSKRESENSKAYA, O., Pozdnyakova, A., Черемных, Е., Chaika, Y. A., & Semina, E. V. (2026) · Brain Sciences · doi:10.3390/brainsci16080831

The brain-gut axis in autism spectrum disorder: from gastrointestinal dysfunction to neuroimmune mechanisms

Fan, F., Wang, B., & Han, F. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1907757

Pre- and probiotics for gastrointestinal and behavioral symptoms in autism spectrum disorder: a systematic review

Dias, M. F., Nogueira, Y. J. D. A., Júnior, A. M. D. Á., Silva, M. C. F., Romano‐Silva, M. A., & de Miranda, D. M. (2026) · Nutritional Neuroscience · doi:10.1080/1028415x.2026.2723173

Electrochemical and optical nanosensors for autism-related biomarkers

Seifi, P., Behmardi, A., Mobed, A., Charsouei, S., & Koohkansaadi, G. (2026) · Microchemical Journal · doi:10.1016/j.microc.2026.119953

Oral versus intranasal probiotics for nasal microbiome modulation: a comparative review of route-dependent mechanisms and clinical implications

Dezzaki, Z. S., Hematian, M., Panah, A. K., Boroujeni, M. R. G., Rahmati, R., & Alipourfard, I. (2026) · Folia Microbiologica · doi:10.1007/s12223-026-01614-y

Comparative Effectiveness of Probiotics, Prebiotics, and Synbiotics for Symptoms of Autism Spectrum Disorder: A Systematic Review and Network Meta-analysis

Zhang, S., Yan, Y., Wang, M., Wei, J., Ma, X., & Xiao, Y. (2026) · Nutrition Reviews · doi:10.1093/nutrit/nuag159

The Interaction Between Gut Microbiota and Neuroinflammation in the Gut-Brain Axis of Autism Spectrum Disorder

Hu, C., Li, H., Li, Y., Huang, S., Wang, W., Zhang, F., Zhao, Y., & Hao, Y. (2026) · Current Neuropharmacology · doi:10.2174/011570159x478343260906114952

The microbiota-gut-brain axis and its potential therapeutic role in autism spectrum disorder

Li, Q., & Zhou, J.-M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.03.013 · Cited by 253 · see citing works

An anxious relationship between Autism Spectrum Disorder and Gut Microbiota: A tangled chemistry?

Vellingiri, B., Aishwarya, S. Y., Jancy, S. B., Abhishek, G. S., Babu, H. W. S., Vijayakumar, P., Narayanasamy, A., Mariappan, S., Sangeetha, R., Gopalakrishnan, A. V., et al. (2022) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2022.03.003 · Cited by 23 · see citing works

Microbiota, Immune System and Autism Spectrum Disorders: An Integrative Model towards Novel Treatment Options

Carpita, B., Marazziti, D., Palego, L., Giannaccini, G., Betti, L., & Dell’Osso, L. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190328151539 · Cited by 40 · see citing works

Neurogastroenterological Dysregulation in Autism Spectrum Disorder: Barrier Function and Neural Communication

dogan, B., & Özdengül, F. (2026) · Medical Research Archives · doi:10.18103/mra.v14i5.7573