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The Autism Diagnostic Observation Schedule—Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders
Open accessAbstract
The Autism Diagnostic Observation Schedule (ADOS; Lord et al., J Autism Dev Disord, 30(3):205-223, 2000) is widely accepted as a "gold standard" diagnostic instrument, but it is of restricted utility with very young children. The purpose of the current project was to modify the ADOS for use in children under 30 months of age. A modified ADOS, the ADOS Toddler Module (or Module T), was used in 360 evaluations. Participants included 182 children with best estimate diagnoses of ASD, non-spectrum developmental delay or typical development. A final set of protocol and algorithm items was selected based on their ability to discriminate the diagnostic groups. The traditional algorithm "cutoffs" approach yielded high sensitivity and specificity, and a new range of concern approach was proposed.
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“Such developmental trajectories might be a more meaningful phenotype on which to map aetiological mechanisms than a static case-control dichotomy 70,139,140”
From Autism spectrum disorder (2020) · cites this paper as [139]
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“Third, although deficits and delays in children who will develop autism can be documented on a group level, diagnosing individual children with ASD prior to age 15-18 months is very difficult (Luyster et al. 2009, Zwaigenbaum et al. 2005).”
From Recent Advances in Autism Research as Reflected in DSM-5 Criteria for Autism Spectrum Disorder (2015) · cites this paper as Luyster et al. 2009
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Items 101–200 of 470
Prince, E. B., Kim, E. S., Wall, C. A., Gisin, E., Goodwin, M. S., Simmons, E. S., Chawarska, K., & Shic, F. (2016) · Autism · doi:10.1177/1362361316648816 · Cited by 65
“All toddlers received a developmental assessment, the Mullen Scales of Early Learning (Mullen, 1995), and an assessment of nonverbal communication skills, the CSBS. Toddlers with ASD also received the Autism Diagnostic Observation Schedule (ADOS-G, Toddler Module; Luyster et al., 2009) from research-reliable clinician…”
MethodInfluentialKnowledge and Attitudes toward Autism Spectrum Disorder in Saudi Arabia
Alyami, H. S., Naser, A. Y., Alyami, M. H., Alharethi, S. H., & Alyami, A. M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063648 · Cited by 59
“It is a semi-structured, standardized examination of social interaction, play, and imaginative material used for people suspected of having ASDs, ranging in age from 12 months to adulthood [11].”
BackgroundMultivariate Neural Connectivity Patterns in Early Infancy Predict Later Autism Symptoms
Dickinson, A. H., Daniel, M., Marin, A., Gaonkar, B., Dapretto, M., McDonald, N. M., & Jeste, S. (2020) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.06.003 · Cited by 66
“A trained clinician administered the Toddler Module of the Autism Diagnostic Observation Schedule-Second Edition (ADOS-T) at 18 months (53,54).”
MethodFrigaux, A., Évrard, R., & Lighezzolo‐Alnot, J. (2019) · L Encéphale · doi:10.1016/j.encep.2019.07.002 · Cited by 75
Al-Qazzaz, N. K., Aldoori, A. A., Buniya, A. K., Ali, S. H. M., & Ahmad, S. A. (2024) · IEEE Access · doi:10.1109/access.2024.3396869 · Cited by 58
“Several widely used clinical procedures for assessing autism spectrum disorder include the Childhood Autism Rating Scale (CARS) [10], Autism Diagnostic Observation Schedule (ADOS) [11] and Autism Diagnostic Interview-Revised (ADI-R) [12].”
MethodDiagnosing autism in neurobiological research studies
Jones, R. M., & Lord, C. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.10.037 · Cited by 56
“The toddler module is intended for children up to 30–36 months of age with a nonverbal ability of 12 months [9, 15].”
BackgroundSelf-citationJanvier, D., Choi, Y. B., Klein, C. B., Lord, C., & Kim, S. H. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-04952-7 · Cited by 57
Self-citationSocial Interaction Test in Home Cage as a Novel and Ethological Measure of Social Behavior in Mice
Kim, D. G., Gonzales, E. L., Kim, S., Kim, Y., Adil, K. J., Jeon, S. J., Cho, K. S., Kwon, K. J., & Shin, C. Y. (2019) · Experimental Neurobiology · doi:10.5607/en.2019.28.2.247 · Cited by 63
Comparison of DSM-IV and DSM-5 Factor Structure Models for Toddlers With Autism Spectrum Disorder
Guthrie, W., Swineford, L. B., Wetherby, A. M., & Lord, C. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2013.05.004 · Cited by 58
“40 Thus, data were missing on Unusual Intonation for 25% of the sample, Immediate Echolalia for 68%, and Stereotyped Language for 81%.”
Self-citationVernon, T. W., Holden, A. N., Barrett, A. C., Bradshaw, J. L., Ko, J. A., McGarry, E. S., Horowitz, E. J., Tagavi, D. M., & German, T. C. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03909-1 · Cited by 56
Riddiford, J. A., Enticott, P. G., Lavale, A., & Gurvich, C. (2022) · Autism Research · doi:10.1002/aur.2729 · Cited by 65
Manelis, L., Meiri, G., Ilan, M., Faroy, M., Michaelovski, A., Flusser, H., Menashe, I., & Dinstein, I. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-04973-2 · Cited by 57
Are the diagnostic rates of autistic females increasing? An examination of state‐wide trends
Harrop, C., Tomaszewski, B. R., Putnam, O. C., Klein, C. B., Lamarche, E., & Klinger, L. G. (2024) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13939 · Cited by 65
Parent Telegraphic Speech Use and Spoken Language in Preschoolers With ASD
Venker, C. E., Bolt, D. M., Meyer, A. T., Sindberg, H. A., Weismer, S. E., & Tager-Flusberg, H. B. (2015) · Journal of Speech Language and Hearing Research · doi:10.1044/2015_jslhr-l-14-0291 · Cited by 52
“…findings from the Autism Diagnostic Observation Schedule (Lord, Rutter, DiLavore, & Risi, 2002) or the Autism Diagnostic Observation Schedule-Toddler Module (ADOS-T; Luyster et al., 2009), and a toddler research version of the Autism Diagnostic Interview-Revised (Rutter, LeCouteur, & Lord, 2003).”
BackgroundMethodde Bildt, A. A., Sytema, S., Zander, E., Bölte, S., Sturm, H., Yirmiya, N., Yaari, M., Charman, T., Salomone, E., Couteur, A. S. L., et al. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2372-2 · Cited by 51
“For the ADOS-2, the revised algorithms for modules 1 and 2 and the algorithms for the Toddler module have shown significant value in the early diagnosis of ASD (Gotham et al. 2007, 2008; Luyster et al. 2009; Molloy et al. 2011; Oosterling et al. 2010b, Overton et al. 2008).”
MethodCharacterization of autism spectrum disorder with spontaneous hemodynamic activity
Li, J., Qiu, L., Xu, L., Pedapati, E. V., Erickson, C. A., & Sunar, U. (2016) · Biomedical Optics Express · doi:10.1364/boe.7.003871 · Cited by 53
on behalf of the TACERN Study Group, Prohl, A. K., Scherrer, B., Tomas-Fernandez, X., Davis, P. E., Filip‐Dhima, R., Prabhu, S. P., Peters, J. M., Bebin, E. M., Krueger, D. A., et al. (2019) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-019-9293-x · Cited by 51
“First, the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) is a semi-structured, interactive observation schedule designed to assess individuals who may have an ASD and consists of 5 modules [35, 36].”
BackgroundVisual attention and autistic behavior in infants with fragile X syndrome
Roberts, J. E., Hatton, D. D., Long, A. C. J., Anello, V., & Colombo, J. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1316-8 · Cited by 50
Early alterations of social brain networks in young children with autism
Sperdin, H. F., Coito, A. L., Kojovic, N., Rihs, T. A., Jan, R. K., Franchini, M., Plomp, G., Vulliémoz, S., Eliez, S., Michel, C. M., et al. (2018) · eLife · doi:10.7554/elife.31670 · Cited by 51
The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults
Bal, V. H., Maye, M. P., Salzman, E., Huerta, M., Pepa, L., Risi, S., & Lord, C. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-04302-8 · Cited by 53
“Analyses to derive A-ADOS algorithms followed a similar procedure to what was used to develop the ADOS-2 Toddler Module (Luyster et al. 2009) and derive ADOS-2 (Gotham et al.”
MethodSelf-citationCraig, F., Crippa, A., Ruggiero, M., Rizzato, V., Russo, L., Fanizza, I., & Trabacca, A. (2021) · Human Movement Science · doi:10.1016/j.humov.2021.102802 · Cited by 52
Hampton, L. H., & Rodriguez, E. (2021) · Autism · doi:10.1177/13623613211050433 · Cited by 48
“Because the opportunity to provide a diagnosis in toddlerhood changed following the introduction of the scoring conventions for toddlers in 2009 (Luyster et al., 2009), we restricted our inclusion criteria to studies after 2009.”
MethodBehavioral interventions for children with autism spectrum disorders
LeBlanc, L. A., & Gillis, J. M. (2012) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2011.10.006 · Cited by 48
“ings suggest that a referral for a comprehensive evaluation is warranted, clinicians have psychometrically sound tools to assist with diagnosing a growing number of children with ASDs at early ages (see the article by Huerta and Lord elsewhere in this issue).(3) Early identification is critically important to ensure t…”
Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder
Constable, P. A., RITVO, E. R., Ritvo, A. R., Lee, I., McNair, M. L., Stahl, D. S., Sowden, J. C., Quinn, S. J., Skuse, D., Thompson, D., et al. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04396-5 · Cited by 48
and the BASIS/STAARS Team, Ali, J. B., Charman, T., Johnson, M. H., & Jones, E. J. H. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04489-1 · Cited by 52
“Further, trained researchers in the BASIS/STAARS teams administered the Autism Diagnostic Observation Schedule Toddler Module (ADOS-T; Luyster et al. 2009) at the 24-month time point.”
Özcan, B., Caligiore, D., Sperati, V., Moretta, T., & Baldassarre, G. (2016) · International Journal of Social Robotics · doi:10.1007/s12369-016-0373-8 · Cited by 46
“Children with autism seem to show a preference in establishing a relationship with these artificial agents [14] and often improve their skills after a therapeutic session based on their use.”
BackgroundRecent developments in neuropathology of autism spectrum disorders
Polšek, D., Jagatic, T., Cepanec, M., Hof, P. R., & Šimić, G. (2011) · Translational Neuroscience · doi:10.2478/s13380-011-0024-3 · Cited by 49
Intellectual functioning and behavioural features associated with mosaicism in fragile X syndrome
Baker, E. K., Arpone, M., Aliaga, S., Bretherton, L., Ure, A. M., Kraan, C. M., Bui, M., Ling, L., Francis, D. I., Hunter, M. F., et al. (2019) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-019-9288-7 · Cited by 48
Exploring Complexity of Facial Dynamics in Autism Spectrum Disorder
Babu, P. R. K., Martino, J. M. D., Chang, Z., Perochon, S., Carpenter, K. L. H., Compton, S. N., Espinosa, S., Dawson, G., & Sapiro, G. (2021) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2021.3113876 · Cited by 47
“If a child screened positive on the M-CHAT-R/F, or a caregiver/clinician expressed any developmental concern, the child was evaluated by a child psychologist based on the Autism Diagnostic Observation Schedule – Toddler (ADOS-T) module [24].”
MethodBarbaro, J., & Yaari, M. (2020) · BMC Pediatrics · doi:10.1186/s12887-019-1888-6 · Cited by 49
Barbaresi, W. J., Cacia, J., Friedman, S., Fussell, J. J., Hansen, R. L., Hofer, J., Roizen, N., Stein, R. E. K., Vanderbilt, D. L., & Sideridis, G. D. (2022) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2022.3605 · Cited by 44
Davidson, M. M., & Weismer, S. E. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3135-z · Cited by 42
“2002), or the ADOS, toddler version (ADOS-T; Luyster et al. 2009) and expert clinical judgment in line with the Diagnostics Statistical Manual of Mental Disorders, Fourth Edition, Text Revised (DSMIV-TR) criteria (American Psychiatric Association 2000).”
ResultDiagnosing Autism Spectrum Disorder in Children with Low Mental Age
Miller, L. E., Burke, J. D., Robins, D. L., & FEIN, D. A. (2018) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-018-3810-8 · Cited by 42
Paolucci, C., Giorgini, F., Scheda, R., Alessi, F. V., & Diciotti, S. (2023) · Computers in Human Behavior · doi:10.1016/j.chb.2023.107877 · Cited by 43
Autism: From research to practice.
Lord, C. (2010) · American Psychologist · doi:10.1037/0003-066x.65.8.815 · Cited by 50
“A research version of a Toddler ADOS Module, intended for toddlers between about 12 and 30 months of age who are walking is now complete (Luyster et al., 2009) and will be available clinically soon.”
InfluentialSelf-citationFranchini, M., Glaser, B., Gentaz, É., de Wilde, H. W., D, S. E. M., & Schaer, M. (2016) · Research in Autism · doi:10.1016/j.rasd.2016.11.010 · Cited by 42
Beaudoin, A. J., Sébire, G., & Couture, M. M. (2019) · Research in Autism · doi:10.1016/j.rasd.2019.101416 · Cited by 39
Talbott, M. R., Young, G. S., MUNSON, J. A., Estes, A. M., Vismara, L. A., & Rogers, S. J. (2018) · Child Development · doi:10.1111/cdev.13203 · Cited by 39
Assessing Communication in Autism Spectrum Disorders
Paul, R., & Fahim, D. (2014) · Wiley eBooks · doi:10.1002/9781118911389.hautc27 · Cited by 36
Brief Report: Autism Symptoms in Infants with Fragile X Syndrome
Roberts, J. E., Tonnsen, B. L., McCary, L. M., Caravella, K. E., & Shinkareva, S. V. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2903-5 · Cited by 37
“The Autism Diagnostic Observation Schedule (ADOS-2; Luyster et al. 2009) is a semi-structured play based measure designed to elicit social interaction.”
Barokova, M. D., Valle, C. L., Hassan, S., Lee, C., Xu, M., McKechnie, R., Johnston, E., Krol, M. A., Leano, J., & Tager-Flusberg, H. B. (2020) · Autism Research · doi:10.1002/aur.2380 · Cited by 42
“Participants were administered a battery of standardized assessments, including the ADOS-2 [Lord et al., 2012] or ADOS — Toddler Module [Luyster et al., 2009] and Mullen Scales of Early Learning (MSEL) [Mullen, 1995], and their parents completed the VABS-3 questionnaire [Sparrow, Cicchetti, & Saulnier, 2016].”
Pierce, K., Glatt, S. J., Liptak, G. S., & McIntyre, L. L. (2009) · Annals of Clinical Psychiatry · doi:10.1177/104012370902100302 · Cited by 37
Self-citationOchoa‐Lubinoff, C., Makol, B. A., & Dillon, E. F. (2023) · Neurologic Clinics · doi:10.1016/j.ncl.2022.10.006 · Cited by 65
Prenatal Tetanus, Diphtheria, Acellular Pertussis Vaccination and Autism Spectrum Disorder
Becerra-Culqui, T. A., Getahun, D. T., Chiu, V. Y., Sy, L. S., & Tseng, H. F. (2018) · PEDIATRICS · doi:10.1542/peds.2018-0120 · Cited by 35
Naheed, A., Islam, M. S., Hossain, S. W., Ahmed, H. U., Uddin, M. J., Tofail, F., Hamadani, J. D., Hussain, A., & Münir, K. (2019) · Autism Research · doi:10.1002/aur.2227 · Cited by 34
“The Modified Checklist for Autism in Toddlers was used for the initial screening of ASD [Robins et al., 2014] and the Autism Diagnostic Observation Schedule was used for diagnosing and assessing the severity of autism in the special schools [Luyster et al., 2009].”
MethodCorona, L. L., Wagner, L., Hooper, M. A., Weitlauf, A. S., Foster, T. E., Hine, J. F., Miceli, A., Nicholson, A. G., Stone, C., Vehorn, A. C., et al. (2023) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-023-05908-9 · Cited by 33
“All psychological providers had achieved research reliability on the ADOS-2 and completed training on the STAT.”
InfluentialPurpura, G., Costanzo, V., Chericoni, N., Puopolo, M., Scattoni, M. L., Muratori, F., & Apicella, F. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01168 · Cited by 34
“In particular, repetitive movements with hands and fingers could represent highly sensitive target behaviors, not only in the administration of the ADOS-2 Toddler Module (Luyster et al., 2009) but also in early risk screening instruments, such as the AOSI (Bryson et al., 2008).”
BackgroundToward Novel Tools for Autism Identification: Fusing Computational and Clinical Expertise
Corona, L. L., Wagner, L., Wade, J. W., Weitlauf, A. S., Hine, J. F., Nicholson, A. G., Stone, C., Vehorn, A. C., & Warren, Z. E. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04857-x · Cited by 33
Stronach, S. T., & Wetherby, A. M. (2017) · American Journal of Speech-Language Pathology · doi:10.1044/2016_ajslp-15-0089 · Cited by 36
“Participants received Module 1, 2, 3, or the Toddler Module (Luyster et al., 2009) on the basis of age and expressive language level.”
Hedley, D., Nevill, R. E. A., Monroy-Moreno, Y., Fields, N., Wilkins, J. W., Butter, E. M., & Mulick, J. A. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2398-5 · Cited by 35
“48) with a confirmed nonverbal developmental level of at least 12 (Toddler module) or 15 months (Module 1 or 2), the minimum recommended developmental age levels for the respective ADOS-2 modules (Luyster et al. 2009).”
BackgroundEapen, V., Woolfenden, S. R., Williams, K. J., Jalaludin, B. B., Dissanayake, C., Axelsson, E. L., Murphy, E., Eastwood, J. G., Descallar, J., Beasley, D., et al. (2014) · BMC Pediatrics · doi:10.1186/1471-2431-14-234 · Cited by 32
“From the remaining 1200 PEDS negative children, every 12th child (n = 100) will also be invited to participate in all the additional assessments (ASQ, ASQ:SE, Modified Checklist for Autism in Toddlers, Mullen Scales of Early Learning, ADOS).”
BackgroundInfluentialCapal, J. K., Horn, P. S., Murray, D. S., Byars, A. W., Bing, N. M., Kent, B., Bucher, L. A., Williams, M. E., O’Kelley, S. E., Pearson, D. A., et al. (2017) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2017.06.010 · Cited by 32
Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners
STURNER, R. A., Howard, B. J., Bergmann, P. E., Attar, S. M., Stewart, L., Bet, K., Allison, C. L., & Baron‐Cohen, S. (2022) · Molecular Autism · doi:10.1186/s13229-021-00480-4 · Cited by 32
“Children were excluded if their parents reported that they were exposed to English at home less than 50% of the time or if they were not yet walking or scooting as required to complete the ADOS-2 Toddler Module [32] for autism diagnostic testing.”
BackgroundMethodInfluentialThe neurobehavioral and molecular phenotype of Angelman Syndrome
Wink, L. K., Fitzpatrick, S. E., Shaffer, R. C., Melnyk, S., Begtrup, A. H., Fox, E., Schaefer, T. L., Mathieu-Frasier, L., Ray, B., Lahiri, D. K., et al. (2015) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.37254 · Cited by 35
“, 2007], and can be over-inclusive in classifying individuals as having ASD when their primary deficit is intellectual or language disability [Luyster et al., 2009].”
BackgroundBishop, S. L., Huerta, M., Gotham, K. O., Havdahl, A., Pickles, A. R., Duncan, A. W., Bal, V. H., Croen, L., & Lord, C. (2016) · Autism Research · doi:10.1002/aur.1645 · Cited by 32
“Children were divided into six age by language groups (see Table 1) on the basis of previous literature about developmental differences in ASD symptom manifestation [Gotham, Risi, Pickles, & Lord, 2007; Lord & Pickles, INSAR Bishop et al./The autism symptom interview 79 1996; Luyster et al., 2009].”
Self-citationTorres, E. B., Nguyen, J., Mistry, S., Whyatt, C. P., Kalampratsidou, V., & Kolevzon, A. (2016) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2016.00022 · Cited by 31
Benedetto, L., Cucinotta, F., Maggio, R., Germanò, E., Raco, R. D., Alquino, A., Impallomeni, C., Siracusano, R., Vetri, L., Roccella, M., et al. (2021) · Brain Sciences · doi:10.3390/brainsci11010037 · Cited by 32
“, Autism Diagnostic Observation Schedule-Toddler—ADOS-T; [30]) and expert clinical opinion [31].”
BackgroundHorvath, S., McDermott, E., Reilly, K. F., & Arunachalam, S. (2018) · Language Speech and Hearing Services in Schools · doi:10.1044/2018_lshss-stlt1-17-0126 · Cited by 36
“Second Edition (ADOS-2; Lord et al., 2012) or ADOS–Toddler Module (Luyster et al., 2009), depending on age, either as part of this study’s protocol or within 12 months as part of a related project.”
MethodParent–Child Interaction Synchrony for Infants At-Risk for Autism Spectrum Disorder
Steiner, A. M., Gengoux, G. W., Smith, A. M., & Chawarska, K. (2018) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-018-3624-8 · Cited by 36
The Behavioral Manifestations of Autism Spectrum Disorders
Kim, S. H., & Lord, C. (2013) · The Neuroscience of Autism Spectrum Disorders · doi:10.1016/b978-0-12-391924-3.00002-8 · Cited by 31
Self-citationRaza, S., Zwaigenbaum, L., Sacrey, L.-A. R., Bryson, S., Brian, J., Smith, I. M., Reid, K., Roberts, W., Szatmari, P., Vaillancourt, T., et al. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03897-2 · Cited by 29
Assessing Gestures in Young Children With Autism Spectrum Disorder
Ellawadi, A. B., & Weismer, S. E. (2013) · Journal of Speech Language and Hearing Research · doi:10.1044/2013_jslhr-l-12-0244 · Cited by 29
“The evaluation included a toddler research version of the Autism Diagnostic Interview—Revised (Rutter, Le Couteur, & Lord, 2003) and the ADOS or ADOS Toddler Module (Luyster et al., 2009).”
MethodSTURNER, R. A., Howard, B. J., Bergmann, P. E., Morrel, T. M., Landa, R. J., Walton, K., & Marks, D. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3231-0 · Cited by 28
Okada, N. J., Liu, J., Tsang, T., Nosco, E., McDonald, N. M., Cummings, K. K., Jung, J., Patterson, G., Bookheimer, S. Y., Green, S. A., et al. (2021) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13555 · Cited by 31
Conti, E., Calderoni, S., Gaglianese, A., Pannek, K., Mazzotti, S., Rose, S., Scelfo, D., Tosetti, M., Muratori, F., Cioni, G., et al. (2015) · Autism Research · doi:10.1002/aur.1533 · Cited by 29
“Also, it has to be noted that it was not possible for us to use the ADOS toddler [Luyster et al., 2009], which is currently considered a more age-appropriate tool, due to the mismatch between time of recruitment and availability of the Italian version of the tool.”
BackgroundRaza, S., Sacrey, L.-A. R., Zwaigenbaum, L., Bryson, S. E., Brian, J. A., Smith, I. M., Roberts, W., Szatmári, P., Vaillancourt, T., Roncadin, C., et al. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03977-3 · Cited by 30
Diagnosis of Autism Spectrum Disorder Across the Lifespan
Shulman, C., Esler, A., Morrier, M. J., & Rice, C. E. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.01.001 · Cited by 32
Self-citationRiva, V., Caruso, A., Apicella, F., Valeri, G., Vicari, S., Molteni, M., & Scattoni, M. L. (2021) · Autism Research · doi:10.1002/aur.2493 · Cited by 27
“At 24 months of age, we used the ADOS Toddler module (Lord et al., 2012; Luyster et al., 2009) to evaluate the symptom severity of ASD.”
MethodEstes, A. M., Yoder, P. J., McEachin, J. J., Hellemann, G., MUNSON, J. A., Greenson, J., Rocha, M., Gardner, E., & Rogers, S. J. (2021) · Autism · doi:10.1177/13623613211005613 · Cited by 32
“We randomized 87 children (21 female and 66 male) age 13–30 months (mean (M) = 22.9; standard deviation (SD) = 4.0) in a multi-site, randomized controlled trial (Intervention Effects of Intensity and Delivery Style for Toddlers With Autism: https://clinicaltrials.gov/; NCT02272192) with an independent data coordinatin…”
MethodInfluentialComplexity analysis of head movements in autistic toddlers
Babu, P. R. K., Martino, J. M. D., Chang, Z., Perochon, S., Aiello, R. E., Carpenter, K. L. H., Compton, S. N., Davis, N. O., Franz, L., Espinosa, S., et al. (2022) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13681 · Cited by 29
Interventions for Toddlers With Autism Spectrum Disorders
Schertz, H. H., Reichow, B., Tan, P., Vaıoulı, P., & Yıldırım, E. (2012) · Journal of Early Intervention · doi:10.1177/1053815112470721 · Cited by 27
Rolison, M. J., Lacadie, C., Chawarska, K., Spann, M. N., & Scheinost, D. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab284 · Cited by 26
“While these two criteria show good convergence (Luyster et al. 2009), incongruent classification between the measures can exist and limit interpretations (especially between the HR-nonASD and ASD groups).”
BackgroundEllawadi, A. B., & Weismer, S. E. (2015) · American Journal of Speech-Language Pathology · doi:10.1044/2015_ajslp-14-0190 · Cited by 30
“The ADOS or Autism Diagnostic Observation Schedule–Toddler Module (ADOS-T; Luyster et al. 2009) were administered.”
MethodRisk for ASD in Preterm Infants: A Three-Year Follow-Up Study
Harel‐Gadassi, A., Friedlander, E., Yaari, M., Bar‐Oz, B., Eventov‐Friedman, S., Mankuta, D., & Yirmiya, N. (2018) · Autism Research and Treatment · doi:10.1155/2018/8316212 · Cited by 28
Dababnah, S., & Parish, S. (2016) · Journal of Evidence-Informed Social Work · doi:10.1080/23761407.2015.1052909 · Cited by 24
“, 1989), Autism Diagnostic Interview—Revised (Rutter, Le Couteur, & Lord, 2003), or Autism Diagnostic Observation Schedule—Toddler Module (Luyster et al., 2009).”
BackgroundMethodCrais, E. R., & Watson, L. R. (2013) · International Journal of Speech-Language Pathology · doi:10.3109/17549507.2013.862860 · Cited by 26
“Although this type of labour-intensive evaluation process may not be practical for community use, there are tools and techniques that can be utilized to gain perspectives of the child at home (e.g., MacArthur-Bates Communicative Development Inventory, Fenson, Marchman, Thal, Dale, Reznick, & Bates, 2007; VABS-2); as s…”
MethodInfluentialGarofoli, F., Lombardi, G., Orcesi, S., Pisoni, C., Mazzucchelli, I., Angelini, M., Balottin, U., & Stronati, M. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3050-3 · Cited by 25
Bruno, J. L., Romano, D., Mazaika, P. K., Lightbody, A. A., Hazlett, H. C., Piven, J., & Reiss, A. L. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1620994114 · Cited by 26
“However, since completion of our data collection, toddler (28) and infant (29) versions of the ADOS have been introduced.”
BackgroundDiagnostic instruments for autism spectrum disorder (ASD)
Vllasaliu, L., Jensen, K., Hoss, S., Landenberger, M., Menze, M., Schütz, M., Ufniarz, K., Kieser, M., & Freitag, C. M. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012036 · Cited by 23
RetractedPsychometric evaluation of the revised child and family quality of life questionnaire (CFQL-2)
Frazier, T. W., Hyland, A. C., Markowitz, L. A., Speer, L. L., & Diekroger, E. A. (2019) · Research in Autism · doi:10.1016/j.rasd.2019.101474 · Cited by 24
Nowell, S. W., Watson, L. R., Crais, E. R., Baranek, G. T., Faldowski, R. A., & Turner‐Brown, L. (2020) · Journal of Speech Language and Hearing Research · doi:10.1044/2020_jslhr-20-00036 · Cited by 24
Hong, J. S., Singh, V., Kalb, L. G., Ashkar, A., & Landa, R. J. (2021) · Autism Research · doi:10.1002/aur.2496 · Cited by 24
“While Luyster et al. (2009) advised that if a child does not have nonverbal mental age of 12 months Toddler Module result may be elevated, our clinical sample showed that Algorithm 1 worked well for those children.”
BackgroundMethodResultInfluentialNarrowband Resting-State fNIRS Functional Connectivity in Autism Spectrum Disorder
Sun, W., Wu, X., Zhang, T., Lin, F., Sun, H., & Li, J. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.643410 · Cited by 23
“, via the Autism Diagnostic Observation Schedule (Luyster et al., 2009).”
MethodAutism spectrum disorder research: knowledge mapping of progress and focus between 2011 and 2022
Jiang, M., Lu, T., Yang, K., Li, X., Zhao, L., Zhang, D., Li, J., & Wang, L. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1096769 · Cited by 26
“Professor Catherine Lord, the top rank for h-index, m-index analysis conducted by the author, and who developed the two gold standards for autism diagnosis (32, 33), are the most influencing factors in the field.”
BackgroundAutomatic recognition of therapy progress among children with autism
Kołakowska, A., Landowska, A., Anzulewicz, A., & Sobota, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-14209-y · Cited by 24
“This is a widely accepted method for analysing therapy progress 20 and as criteria in autism diagnosis–e.g. according to DSM-V 21 .”
MethodCheng, H., Yu, J., Xu, L., & Li, J. (2019) · Biomedical Optics Express · doi:10.1364/boe.10.001383 · Cited by 23
Al-Salehi, S. M., & Alhifthy, E. H. (2020) · Springer eBooks · doi:10.1007/978-3-319-43153-6_10 · Cited by 23
Social attention as a cross‐cultural transdiagnostic neurodevelopmental risk marker
Frazier, T. W., Uljarević, M., Ghazal, I., Klingemier, E. W., Langfus, J. A., Youngstrom, E. A., Aldosari, M., Al‐Shammari, H., Elhag, S. F., Tolefat, M., et al. (2021) · Autism Research · doi:10.1002/aur.2532 · Cited by 23
“The ADOS-2 considered the gold-standard clinical observation measures for assessing autism symptom severity was used (Lord et al., 2012; Luyster et al., 2009).”
MethodReplication study for ADOS ‐2 cut‐offs to assist evaluation of autism spectrum disorder
Hong, J. S., Singh, V., Kalb, L. G., Reetzke, R., Ludwig, N. N., Pfeiffer, D. L., Holingue, C., Menon, D. U., Lu, Q., Ashkar, A., et al. (2022) · Autism Research · doi:10.1002/aur.2801 · Cited by 24
Liu, J., Chen, L., Chang, H., Rudoler, J., Al-Zughoul, A. B., Kang, J. B., Abrams, D. A., & Menon, V. (2023) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2023.05.002 · Cited by 23
“The diagnosis of ASD was con fi rmed by an experienced clinical psychologist using the standard criteria based on the Autism Diagnostic Interview-Revised (28) and/or the Autism Diagnostic Observation Schedule (29).”
MethodOlaguez-Gonzalez, J. M., Chaírez, I., Bretón‐Deval, L., & Alfaro-Ponce, M. (2023) · Biomedicines · doi:10.3390/biomedicines11102633 · Cited by 26
Tran, X. A., McDonald, N. M., Dickinson, A. H., Scheffler, A., Frohlich, J., Marin, A., Liu, C. K., Nosco, E., Şentürk, D., Dapretto, M., et al. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.15005 · Cited by 22
“Autism spectrum disorder symptomatology was measured using the Autism Diagnostic Observation Scale Toddler Module (ADOS-T; Luyster et al., 2009).”
MethodInfluentialDSM-5 Diagnostic Criteria for Autism Spectrum Disorder With Implications for School Psychologists
Esler, A., & Ruble, L. A. (2015) · International Journal of School & Educational Psychology · doi:10.1080/21683603.2014.890148 · Cited by 29
Self-citationHeart rate-defined sustained attention in infants at risk for autism
Tonnsen, B. L., Richards, J. E., & Roberts, J. E. (2018) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-018-9224-2 · Cited by 24
“The Autism Diagnostic Observation Schedule—Toddler Module (ADOS-T) [53] is a well-established diagnostic”
InfluentialSocial endophenotypes in autism spectrum disorder: A scoping review
Tiede, G., & Walton, K. M. (2020) · Development and Psychopathology · doi:10.1017/s0954579420000577 · Cited by 21
“Joint attention skills are compromised in young children with ASD (Mundy, 2018), to the degree that they are central to diagnosis in young children (Lord et al., 2012; Luyster et al., 2009) (G&G 1).”
BackgroundBieneck, V., Bletsch, A., Mann, C., Schäfer, T., Seelemeyer, H., Herøy, N., Zimmermann, J., Pretzsch, C. M., Hattingen, E., & Ecker, C. (2021) · Genes · doi:10.3390/genes12122024 · Cited by 25
“, the German version of the Autism Diagnostic Interview-Revised (ADI-R; [29,30]) and the second edition of the Autism Diagnostic Observation Schedule (ADOS-2; [31,32]).”
Autistische Störungen – State-of-the-Art und neuere Entwicklungen
Freitag, C. M. (2012) · Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie · doi:10.1024/1422-4917/a000164 · Cited by 22
The course and prognostic capability of motor difficulties in infants showing early signs of autism
Licari, M. K., Varcin, K. J., Hudry, K., Leonard, H. C., Alvares, G. A., Pillar, S. V., Stevenson, P. G., Cooper, M. N., Whitehouse, A., & the AICES Team (2021) · Autism Research · doi:10.1002/aur.2545 · Cited by 22
“The Autism Diagnostic Observation Schedule – Toddler Module (ADOS-T, 37) is a semi-structured assessment designed to elicit behaviors relevant to ASD in toddlers aged 12–30 months (Luyster et al., 2009).”
BackgroundProsperi, M., Santocchi, E., Muratori, F., Narducci, C., Calderoni, S., Tancredi, R., Morales, M. A., & Guiducci, L. (2019) · BMC Pediatrics · doi:10.1186/s12887-019-1841-8 · Cited by 22
Latrèche, K., Godel, M., Franchini, M., Journal, F., Kojovic, N., & Schaer, M. (2024) · Autism · doi:10.1177/13623613241253015 · Cited by 34
“To compare scores across modules we used calibrated severity scores (Gotham et al., 2009; Hus et al., 2014) to obtain SA and RRB severity scores.”
Metadata
- Authors
- Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., Pierce, K., Bishop, S., Esler, A., Hus, V., Oti, R., Richler, J., Risi, S., & Lord, C.
- Affiliations
- Harvard University (US)
- University of Michigan (US)
- University of California San Diego (US)
- University of Wisconsin System (US)
- University of Minnesota (US)
- Corresponding author
- Luyster, Rhiannon
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2009-05-05
- Volume
- 39
- Issue
- 9
- Pages
- 1305-1320
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- PMC
- PMC2893552
- OpenAlex
- W2022345199
- Cited by
- 468
- References
- 39
- Citations by year
- 2026: 16 · 2025: 19 · 2024: 32 · 2023: 30 · 2022: 42 · 2021: 47 · 2020: 36 · 2019: 33 · 2018: 25 · 2017: 22 · 2016: 24 · 2015: 31 · 2014: 18 · 2013: 23 · 2012: 36
- FWCI
- 11.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Funders
- Simons Foundation
- National Institutes of Health
- National Institute of Mental Health (R01MH066496, F31MH73210-02, R25MH057167, R01MH078165, F32MH066469, R01MH080134, MH066469, F31MH073210, MH57167)
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U19HD035482, HD-35482-01, P01HD035482)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- Autism Diagnostic Observation Schedule, autism spectrum disorder, toddlers, diagnostic assessment, diagnostic algorithm, cut-off values, sensitivity and specificity, developmental delay, young children
- MeSH terms
- Affect, Algorithms, Attention, Autistic Disorder, Awareness, Developmental Disabilities, Child, Preschool, Diagnosis, Differential, Female, Humans, Infant, Language Development Disorders, Male, Personality Assessment, Pilot Projects, Play and Playthings, Psychometrics, Reference Standards, Social Behavior, Verbal Behavior, Reproducibility of Results
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