Personality traits as risk factors for stroke and coronary heart disease mortality: pooled analysis of three cohort studies
Abstract
We examined whether personality traits are differently associated with coronary heart disease and stroke mortality. Participants were pooled from three prospective cohort studies (Health and Retirement Study, Wisconsin Longitudinal Study graduate and sibling samples; n = 24,543 men and women, mean age 61.4 years, mortality follow-up between 3 and 15 years). There were 423 coronary heart disease deaths and 88 stroke deaths during 212,542 person-years at risk. Higher extraversion was associated with an increased risk of stroke (hazard ratio per each standard deviation increase in personality trait HR = 1.41, 95 % CI 1.10-1.80) but not with coronary heart disease mortality (HR = 0.93, 0.83-1.05). High neuroticism, in turn, was more strongly related to the risk of coronary heart disease (HR = 1.16, 1.04-1.29) than stroke deaths (HR = 0.95, 0.78-1.17). High conscientiousness was associated with lower mortality risk from both coronary heart disease (HR = 0.74, 0.67-0.81) and stroke (HR = 0.78, 0.63-0.97). Cardiovascular risk associated with personality traits appears to vary between main cardiac and cerebral disease endpoints.
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Conscientiousness and neuroticism consistently predict cardiovascular and all-cause mortality, among other outcomes.
“Conscientiousness (a tendency toward self-discipline, reliability, and orderliness) and neuroticism (proneness to negative emotionality) in particular consistently predict cardiovascular and all-cause mortality, among other outcomes (8,10-12).”
From Socioeconomic Status Interacts with Conscientiousness and Neuroticism to Predict Circulating Concentrations of Inflammatory Markers (2017) · cites this paper as [12]
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- Authors
- Jokela, M., Pulkki-Råback, L., Elovainio, M., & Kivimäki, M.
- Affiliations
- University of Helsinki (FI)
- Finnish Institute for Health and Welfare (FI)
- Corresponding author
- Jokela, Markus
- Venue
- Journal of Behavioral Medicine
- Published
- 2013-11-08
- Volume
- 37
- Issue
- 5
- Pages
- 881-889
- ISSN
- 0160-7715 (ISSN-L)
- 1573-3521
- OpenAlex
- W2023153771
- Cited by
- 269
- References
- 60
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 9 · 2023: 62 · 2022: 22 · 2021: 18 · 2020: 53 · 2019: 19 · 2018: 19 · 2017: 15 · 2016: 18 · 2015: 11 · 2014: 8 · 2012: 2
- FWCI
- 8.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Behavioral Medicine (publishedVersion)
- PubMed (publishedVersion)
- STM:n Hallinnonalan avoin julkaisuarkisto (Julkari) (submittedVersion)
- Funders
- British Heart Foundation (RG/13/2/30098)
- Juho Vainion Säätiö
- Medical Research Council (MR/K013351/1)
- Economic and Social Research Council (ES/J023299/1)
- National Institute on Aging (R01AG034454)
- National Heart, Lung, and Blood Institute (R01HL036310)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- personality traits, stroke mortality, coronary heart disease mortality, extraversion, neuroticism, conscientiousness, Big Five personality traits, cardiovascular risk, older adults
- MeSH terms
- Neuroticism, Aged, Anxiety Disorders, Coronary Disease, Extraversion, Psychological, Female, Humans, Male, Middle Aged, Personality, Personality Assessment, Risk Factors, Cohort Studies, Stroke
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