An item response analysis of the pediatric PROMIS anxiety and depressive symptoms scales
Open accessAbstract
Purpose The Patient-Reported Outcomes Measurement Information System (PROMIS) aims to develop self-reported item banks for clinical research. The PROMIS pediatrics (aged 8-17) project focuses on the development of item banks across several health domains (physical function, pain, fatigue, emotional distress, social role relationships, and asthma symptoms). The psychometric properties of the anxiety and depressive symptom item banks are described. Methods Participants (n = 1,529) were recruited in public school settings, hospital-based outpatient and subspecialty pediatrics clinics. The anxiety (k = 18) and depressive symptoms (k = 21) items were split between two test administration forms. Hierarchical confirmatory factor-analytic models (CFA) were conducted to evaluate scale dimensionality and local dependence. IRT analyses were then used to finalize item banks and short forms. Results CFA results confirmed that anxiety and depressive symptoms are separate constructs and indicative of negative affect. Items with local dependence and DIF were removed resulting in 15 anxiety and 14 depressive symptoms items. The psychometric differences between short forms and simulated computer adaptive tests are presented. Conclusions PROMIS pediatric item banks were developed to provide efficient assessment of health-related quality of life domains. This sample provides initial calibrations of anxiety and depressive symptoms item banks and creates PROMIS pediatric instruments, version 1.0.
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Adolescents with symptomatic GJH aged 12-18 years have a moderate level of anxiety, with 12% scoring above the clinical cutoff for elevated anxiety.
“Adolescents with symptomatic GJH aged 12-18 years had a moderate level of anxiety, with 12% of the patients scoring above the clinical cutoff59 for elevated anxiety.55”
From Role of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review (2025) · cites this paper as [59]
The Results describe development and testing of pediatric anxiety items in a sample of 1,529 children, not anxiety outcomes in adolescents with symptomatic GJH. Searches for GJH or hypermobility, moderate anxiety, and the claimed 12% found no passage reporting that finding. The clinical-cutoff citation is separately numbered 59 in the citing sentence. (LLM, conf=0.78)
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MethodRole of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review
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“59,60 61-63 This preference to avoid mental support is also found in adolescents with chronic pain and GJH who tend to focus on the physical nature of their pain and even downplay their levels of psychological distress and anxiety themselves when seeking medical help.”
- Authors
- Irwin, D. E., Stucky, B., Langer, M. M., Thissen, D., DeWitt, E. M., Lai, J.-S., Varni, J. W., Yeatts, K., & DeWalt, D. A.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- National Board of Medical Examiners (US)
- Duke Medical Center (US)
- Northwestern University (US)
- Texas A&M University (US)
- Corresponding author
- Irwin, Debra E.
- Venue
- Quality of Life Research
- Published
- 2010-03-07
- Volume
- 19
- Issue
- 4
- Pages
- 595-607
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- PMC
- PMC3158603
- OpenAlex
- W2084427790
- Cited by
- 537
- References
- 7
- Citations by year
- 2026: 55 · 2025: 58 · 2024: 56 · 2023: 50 · 2022: 57 · 2021: 49 · 2020: 43 · 2019: 29 · 2018: 26 · 2017: 28 · 2016: 24 · 2015: 13 · 2014: 14 · 2013: 20 · 2012: 5
- FWCI
- 13.97
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Quality of Life Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR052181)
- Topics
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- PROMIS, childhood anxiety, depressive symptoms, item bank, item response theory, computerized adaptive testing, short form, local dependence, differential item functioning, health-related quality of life, negative affect, psychometric properties, children and adolescents
- MeSH terms
- Adaptation, Psychological, Adolescent, Anxiety, Child, Depression, Female, Humans, Male, North Carolina, Outpatients, Pediatrics, Psychometrics, Self Concept, Stress, Psychological, Texas
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